Page last updated: 2024-08-23

lonidamine and Lung Neoplasms

lonidamine has been researched along with Lung Neoplasms in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19908 (27.59)18.7374
1990's17 (58.62)18.2507
2000's2 (6.90)29.6817
2010's2 (6.90)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Biemans, R; Bussink, J; Dubois, LJ; Meijer, TWH; Peeters, WJM; Span, PN; van Gisbergen, MW; Venhuizen, JH1
Chang, AC; Chen, G; Cheng, G; Hardy, M; Kalyanaraman, B; Kresty, L; Lee, Y; Myers, CR; Ouari, O; Pan, J; Weh, K; You, M; Zhang, Q; Zielonka, J; Zielonka, M1
Carlini, P; Cognetti, F; Di Cosimo, S; Fabi, A; Ferretti, G; Papaldo, P1
Konovalova, NP1
Caputo, A; Silvestrini, B1
Brunner, KW; Cavalli, F; Goldhirsch, A; Joss, RA; Mermillod, B1
Ciottoli, GB; De Gregorio, M; Kokron, O; Maca, S; Scheiner, W1
Buccheri, G; Ferrigno, D1
Nardini, S1
Evans, G; McCunniff, AJ; Paggiarino, DA; Scarantino, CW; Young, CW1
Berni, F; Calzavara, MP; Cattaneo, MT; D'Adda, D; Filipazzi, V; Frontini, L; Isa, L; Legnani, W; Rho, B; Scapaticci, R1
Buccheri, G; Ferrigno, D; Rosso, A1
Brancaccio, L; Carnicelli, P; Cioffi, R; Comella, P; De Cataldis, G; Ianniello, GP; Lombardi, A; Maiorino, A; Scarpati, MD; Tinessa, V1
Bianco, A; Bilancia, D; Carpagnano, F; Cioffi, R; Comella, G; Comella, P; De Cataldis, G; De Lena, M; Di Rienzo, G; Frasci, G; Lorusso, V; Maiorino, L; Manzione, L; Natale, M; Nicolella, G; Pacilio, C; Panza, N1
Kimura, I; Kiura, K; Ohnoshi, T; Segawa, Y; Shibayama, T; Tabata, M; Takigawa, N; Ueoka, H1
Christoffel, V; Gatzemeier, U; Lücker, PW; Picollo, R; Toomes, H; Ulmer, J1
Eble, M; Flentje, M; Hör, A; Latz, D; Wannenmacher, M1
Contu, A; Deriu, A; Olmeo, NA; Ortu, S; Paga, C; Pani, P1
Cionini, L1
Cavalli, F; Gatzemeier, U; Häussinger, K; Kaukel, E; Koschel, G; Martinelli, G; Neuhauss, R; von Pawel, J1
Hardy, JR; Jones, AL; Newell, DR; Smith, IE1
Canova, N; Casadio, M; Guaraldi, M; Lelli, G; Pannuti, F1
Button, D; Catanese, B; Hardy, J; Jenns, K; Mansi, J; Newell, DR; Picollo, R; Smith, IE1
Ciottoli, GB; De Gregorio, M; Kokron, O; Maca, S1
Bagatella, M; Bonardi, G; Calciati, A; Donadio, M; Giaccone, G; Maestroni, F1
Albera, C; Gozzelino, F; Pescetti, G; Scagliotti, GV1
Band, P; Murray, N; Shah, A1
Ambesi Impiombato, F; Antilli, A; Ciottoli, GB; De Gregorio, M; Del Vecchio, MR; Gallo-Curcio, C; Rinaldi, M; Tonachella, R; Tropea, F; Verturo, I1
Ciottoli, GB; De Gregorio, M; De Luca, B; Greco, S; Magnani, F; Marletta, F; Palmucci, T; Patanè, C; Privitera, G; Tafuri, G1

Reviews

5 review(s) available for lonidamine and Lung Neoplasms

ArticleYear
Lonidamine: efficacy and safety in clinical trials for the treatment of solid tumors.
    Drugs of today (Barcelona, Spain : 1998), 2003, Volume: 39, Issue:3

    Topics: Aged; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Clinical Trials as Topic; Female; Humans; Indazoles; Lung Neoplasms; Male; Ovarian Neoplasms; Safety

2003
Lonidamine, a new approach to cancer therapy.
    Oncology, 1984, Volume: 41 Suppl 1

    Topics: Abnormalities, Drug-Induced; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cell Division; Diuresis; Female; Indazoles; Kidney; Leukemia P388; Lung Neoplasms; Male; Mitochondria; Oxygen Consumption; Pregnancy; Pyrazoles; Sarcoma 180; Spermatogenesis

1984
New agents in non-small cell lung cancer.
    Cancer treatment reviews, 1984, Volume: 11, Issue:3

    Topics: Adenocarcinoma; Adult; Alkylating Agents; Animals; Anthraquinones; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Carcinoma; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Drug Evaluation; Etoposide; Female; Humans; Ifosfamide; Indazoles; Lung Neoplasms; Male; Mice; Mitoxantrone; Triazines; Vinblastine; Vindesine

1984
Non small cell lung cancer and chemotherapy.
    Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace, 1994, Volume: 49, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Fluorouracil; Humans; Indazoles; Lomustine; Lung Neoplasms; Methotrexate; Neoplasm Staging; Treatment Outcome

1994
Radiotherapy plus lonidamine in non-small cell lung cancer.
    Seminars in oncology, 1991, Volume: 18, Issue:2 Suppl 4

    Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Humans; Indazoles; Lung Neoplasms

1991

Trials

11 trial(s) available for lonidamine and Lung Neoplasms

ArticleYear
New agents in non-small cell lung cancer.
    Cancer treatment reviews, 1984, Volume: 11, Issue:3

    Topics: Adenocarcinoma; Adult; Alkylating Agents; Animals; Anthraquinones; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Carcinoma; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Drug Evaluation; Etoposide; Female; Humans; Ifosfamide; Indazoles; Lung Neoplasms; Male; Mice; Mitoxantrone; Triazines; Vinblastine; Vindesine

1984
A randomised trial of MACC chemotherapy with or without lonidamine in advanced non-small cell lung cancer. Cuneo Lung Cancer Study Group (CuLCaSG)
    European journal of cancer (Oxford, England : 1990), 1994, Volume: 30A, Issue:10

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Humans; Indazoles; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Survival Analysis

1994
A prospective randomized comparison of radiation therapy plus lonidamine versus radiation therapy plus placebo as initial treatment of clinically localized but nonresectable nonsmall cell lung cancer.
    International journal of radiation oncology, biology, physics, 1994, Jul-30, Volume: 29, Issue:5

    Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Combined Modality Therapy; Double-Blind Method; Humans; Indazoles; Lung Neoplasms; Male; Prospective Studies; Radiation-Sensitizing Agents

1994
A phase II study of methotrexate, doxorubicin, cyclophosphamide, and lomustine chemotherapy and lonidamine in advanced non-small cell lung cancer.
    Cancer, 1993, Sep-01, Volume: 72, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Tolerance; Female; Follow-Up Studies; Humans; Indazoles; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Staging; Pilot Projects; Remission Induction; Survival Rate

1993
Cisplatin, epirubicin, and vindesine with or without lonidamine in the treatment of inoperable nonsmall cell lung carcinoma: a multicenter randomized clinical trial.
    Cancer, 1996, Jul-01, Volume: 78, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplatin; Disease Progression; Epirubicin; Female; Humans; Indazoles; Lung Neoplasms; Male; Middle Aged; Survival Analysis; Vindesine

1996
Cisplatin, gemcitabine, and vinorelbine combination therapy in advanced non-small-cell lung cancer: a phase II randomized study of the Southern Italy Cooperative Oncology Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1999, Volume: 17, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplatin; Deoxycytidine; Disease-Free Survival; Epirubicin; Female; Follow-Up Studies; Gemcitabine; Humans; Indazoles; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Proportional Hazards Models; Quality of Life; Vinblastine; Vindesine; Vinorelbine

1999
Lonidamine in non-small-cell lung cancer: a phase II study.
    Tumori, 1991, Feb-28, Volume: 77, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Drug Evaluation; Humans; Indazoles; Liver; Lung Neoplasms; Male; Middle Aged

1991
Phase III trial with and without lonidamine in non-small cell lung cancer.
    Seminars in oncology, 1991, Volume: 18, Issue:2 Suppl 4

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Clinical Trials as Topic; Female; Humans; Indazoles; Lung Neoplasms; Male; Middle Aged; Mitomycin; Mitomycins; Neoplasm Staging; Prospective Studies; Remission Induction; Survival Rate; Time Factors; Vindesine

1991
Lonidamine versus polychemotherapy in advanced non-small-cell lung cancer. A preliminary analysis.
    Tumori, 1989, Feb-28, Volume: 75, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplatin; Female; Humans; Indazoles; Lung Neoplasms; Male; Middle Aged; Mitomycins; Pyrazoles; Vinblastine

1989
Chemotherapy/radiation therapy plus/minus lonidamine in the treatment of non-small cell lung cancer (limited disease): preliminary results.
    Seminars in oncology, 1988, Volume: 15, Issue:6 Suppl 7

    Topics: Adult; Aged; Carcinoma, Non-Small-Cell Lung; Combined Modality Therapy; Female; Humans; Indazoles; Lung Neoplasms; Male; Middle Aged; Prospective Studies; Pyrazoles; Random Allocation; Time Factors

1988
Phase II double-blind randomized study of lonidamine and radiotherapy in epidermoid carcinoma of the lung.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1987, Volume: 10, Issue:4

    Topics: Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Combined Modality Therapy; Double-Blind Method; Drug Evaluation; Female; Humans; Indazoles; Lung Neoplasms; Male; Middle Aged; Pyrazoles

1987

Other Studies

14 other study(ies) available for lonidamine and Lung Neoplasms

ArticleYear
Targeting glucose and glutamine metabolism combined with radiation therapy in non-small cell lung cancer.
    Lung cancer (Amsterdam, Netherlands), 2018, Volume: 126

    Topics: Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Radiation; Enzyme Inhibitors; Glucose; Glutaminase; Glutamine; Glycolysis; Humans; Indazoles; Lung Neoplasms; Radiation Tolerance; X-Rays

2018
Targeting lonidamine to mitochondria mitigates lung tumorigenesis and brain metastasis.
    Nature communications, 2019, 05-17, Volume: 10, Issue:1

    Topics: Animals; Antineoplastic Agents; Autophagy; Brain Neoplasms; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Drug Delivery Systems; Electron Transport Complex I; Electron Transport Complex II; Female; Humans; Indazoles; Lung Neoplasms; Mice; Mice, Inbred NOD; Mice, Nude; Mice, SCID; Mitochondria; Reactive Oxygen Species; Xenograft Model Antitumor Assays

2019
Ultralow doses of various drugs in chemotherapy of experimental tumors.
    Bulletin of experimental biology and medicine, 2003, Volume: 135 Suppl 7

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Indazoles; Leukemia P388; Lung Neoplasms; Melanoma; Mice; Mitomycin; Neoplasm Metastasis; Neoplasms, Experimental; Triazoles; Xenograft Model Antitumor Assays

2003
Phase II study of lonidamine in inoperable non-small-cell lung cancer.
    Oncology, 1984, Volume: 41 Suppl 1

    Topics: Aged; Antineoplastic Agents; Digestive System; Drug Evaluation; Female; Humans; Indazoles; Lung Neoplasms; Male; Middle Aged; Muscles; Pyrazoles

1984
Cisplatin plus epirubicin and etoposide followed by irradiation plus lonidamine in stage III nonsmall cell lung cancer.
    Oncology, 1993, Volume: 50, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Humans; Indazoles; Lung Neoplasms; Male; Middle Aged

1993
An adriamycin-resistant subline is more sensitive than the parent human small cell lung cancer cell line to lonidamine.
    Anti-cancer drug design, 1992, Volume: 7, Issue:6

    Topics: Antineoplastic Agents; Carcinoma, Small Cell; Cisplatin; Doxorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Etoposide; Humans; Indazoles; Lung Neoplasms; Tumor Cells, Cultured

1992
Single- and multiple dose pharmacokinetics of lonidamine in patients suffering from non-small-cell lung cancer.
    Arzneimittel-Forschung, 1991, Volume: 41, Issue:4

    Topics: Adult; Aged; Aging; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Chromatography, Gas; Chromatography, High Pressure Liquid; Female; Humans; Indazoles; Liver; Lung Neoplasms; Male; Middle Aged

1991
[Effects of lonidamine alone or in combination with radiotherapy on survival and metabolism in human and rodent cell lines].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1991, Volume: 167, Issue:12

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Line; Cell Survival; Combined Modality Therapy; Cricetinae; Cricetulus; Humans; Hydrogen-Ion Concentration; Indazoles; Lung Neoplasms; Mice; Mitochondria; Oxidoreductases; Radiotherapy Dosage; Tetrazolium Salts; Tumor Cells, Cultured

1991
Clinical study and pharmacokinetics of lonidamine in advanced non-small cell lung cancer.
    European journal of cancer (Oxford, England : 1990), 1991, Volume: 27, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Drug Evaluation; Female; Humans; Indazoles; Lung Neoplasms; Male; Middle Aged

1991
A phase II study on lonidamine combined with cisplatin and etoposide in the treatment of advanced non-small cell bronchogenic carcinoma (NSCBC).
    Journal of chemotherapy (Florence, Italy), 1990, Volume: 2, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Bronchogenic; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cisplatin; Drug Evaluation; Etoposide; Female; Humans; Indazoles; Lung Neoplasms; Male; Middle Aged; Remission Induction

1990
The pharmacokinetics of oral lonidamine in breast and lung cancer patients.
    Seminars in oncology, 1991, Volume: 18, Issue:2 Suppl 4

    Topics: Absorption; Administration, Oral; Aged; Antineoplastic Agents; Breast Neoplasms; Chromatography, High Pressure Liquid; Drug Administration Schedule; Drug Tolerance; Female; Fluorescence; Humans; Indazoles; Lung Neoplasms; Male; Middle Aged; Tablets; Time Factors

1991
Phase II study of lonidamine in non-small cell lung cancer: final report.
    British journal of cancer, 1990, Volume: 61, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Drug Evaluation; Female; Humans; Indazoles; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Pyrazoles

1990
Chronic administration of lonidamine in untreated non-small cell lung cancer of stage III M0-1.
    Chemotherapy, 1989, Volume: 35, Issue:1

    Topics: Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Female; Humans; Indazoles; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Pyrazoles

1989
Phase II study of lonidamine in patients with small cell carcinoma of the lung.
    Cancer treatment reports, 1987, Volume: 71, Issue:12

    Topics: Adult; Aged; Carcinoma, Small Cell; Drug Evaluation; Female; Humans; Indazoles; Lung Neoplasms; Male; Middle Aged; Pyrazoles

1987