lonidamine has been researched along with Brain Neoplasms in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (28.57) | 18.7374 |
| 1990's | 5 (35.71) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 2 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, AC; Chen, G; Cheng, G; Hardy, M; Kalyanaraman, B; Kresty, L; Lee, Y; Myers, CR; Ouari, O; Pan, J; Weh, K; You, M; Zhang, Q; Zielonka, J; Zielonka, M | 1 |
| Bartha, R; Li, AX; McVicar, N; Meakin, SO | 1 |
| Kalia, VK; Prabhakara, S | 1 |
| Kalia, VK; Narayanan, V; Prabhakara, S | 1 |
| Andrieu, JM; Banu, E; Carpentier, A; Celerier, D; Delattre, JY; Dutrillaux, B; Fauchon, F; Oudard, S; Poupon, MF | 1 |
| Carapella, CM; Delle Chiaie, S; Iandolo, B; Riccio, A | 1 |
| Eapen, L; Evans, WK; Genest, P; Girard, A; Stewart, DJ; Verma, S | 1 |
| Ben-Yoseph, O; Lyons, JC; Ross, BD; Song, CW | 1 |
| Bourgeois, Y; Bras Gonçalves, R; Dutrillaux, B; Miccoli, L; Oudard, S; Poirson-Bichat, F; Poupon, MF; Sureau, F | 1 |
| Dutrillaux, B; Miccoli, L; Oudard, S; Poupon, MF | 1 |
| Sales, S; Schiffer, D; Soffietti, R | 1 |
| Caputo, A; Carapella, CM; Cattani, F; Ciottoli, GB; Floridi, A; Iandolo, B; Paggi, MG; Raus, L; Riccio, A | 1 |
| Currie, VE; DeAngelis, LM; Farag, FM; Kim, JH; Krol, G; O'Hehir, MA; Posner, JB; Young, CW | 1 |
| Caputo, A; Del Carlo, C; Fanciulli, M; Floridi, A; Giorno, S; Laudonio, N; Paggi, MG; Silvestrini, B; Zupi, G | 1 |
2 review(s) available for lonidamine and Brain Neoplasms
| Article | Year |
|---|---|
[Targeting the gene of glucose metabolism for the treatment of advanced gliomas].
Topics: Antineoplastic Agents; Brain; Brain Neoplasms; Chromosome Deletion; Diazepam; Glioma; Glucose; Glycolysis; Hexokinase; Humans; Indazoles; Mitochondria; Neoplasm Proteins; Porins; Tumor Cells, Cultured | 1998 |
Lonidamine in malignant brain tumors.
Topics: Antineoplastic Agents; Brain Neoplasms; Glioma; Humans; Indazoles | 1991 |
4 trial(s) available for lonidamine and Brain Neoplasms
| Article | Year |
|---|---|
Phase II study of lonidamine and diazepam in the treatment of recurrent glioblastoma multiforme.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Diazepam; Female; Glioblastoma; Humans; Indazoles; Male; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Survival Rate | 2003 |
Phase II study of lonidamine plus radiotherapy in the treatment of brain metastases.
Topics: Adult; Aged; Brain Neoplasms; Combined Modality Therapy; Cranial Irradiation; Dexamethasone; Female; Humans; Indazoles; Male; Middle Aged; Muscular Diseases; Pain; Survival Analysis; Treatment Outcome | 1993 |
The potential role of lonidamine (LND) in the treatment of malignant glioma. Phase II study.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Clinical Trials as Topic; Dose-Response Relationship, Drug; Female; Glioma; Humans; Indazoles; Male; Middle Aged; Neoplasm Recurrence, Local; Pyrazoles | 1989 |
The combined use of radiation therapy and lonidamine in the treatment of brain metastases.
Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Female; Humans; Indazoles; Male; Middle Aged; Prospective Studies; Pyrazoles; Randomized Controlled Trials as Topic | 1989 |
8 other study(ies) available for lonidamine and Brain Neoplasms
| Article | Year |
|---|---|
Targeting lonidamine to mitochondria mitigates lung tumorigenesis and brain metastasis.
Topics: Animals; Antineoplastic Agents; Autophagy; Brain Neoplasms; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Drug Delivery Systems; Electron Transport Complex I; Electron Transport Complex II; Female; Humans; Indazoles; Lung Neoplasms; Mice; Mice, Inbred NOD; Mice, Nude; Mice, SCID; Mitochondria; Reactive Oxygen Species; Xenograft Model Antitumor Assays | 2019 |
Imaging chemical exchange saturation transfer (CEST) effects following tumor-selective acidification using lonidamine.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Contrast Media; Humans; Hydrogen-Ion Concentration; Image Interpretation, Computer-Assisted; Indazoles; Magnetic Resonance Imaging; Mice; Mice, Nude; Molecular Imaging; Reproducibility of Results; Sensitivity and Specificity; Tumor Cells, Cultured | 2015 |
Optimizing radiotherapy of brain tumours by a combination of temozolomide & lonidamine.
Topics: Acridine Orange; Analysis of Variance; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Gamma Rays; Humans; Indazoles; Radiation-Sensitizing Agents; Radiotherapy; Temozolomide | 2008 |
Modulation of cellular radiation responses by 2-deoxy-D-glucose and other glycolytic inhibitors: implications for cancer therapy.
Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Deoxyglucose; Glioma; Humans; Indazoles; Micronucleus Tests; Radiation-Sensitizing Agents | 2009 |
Lonidamine in primary malignant brain tumors. Preliminary report.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Electrocardiography; Electromyography; Female; Glioma; Humans; Indazoles; Male; Middle Aged; Pyrazoles; Tomography, X-Ray Computed | 1984 |
Mechanism of action of lonidamine in the 9L brain tumor model involves inhibition of lactate efflux and intracellular acidification.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Gliosarcoma; Hydrogen-Ion Concentration; Indazoles; Injections, Subcutaneous; Intracellular Fluid; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Muscle Neoplasms; Neoplasm Transplantation; Phosphorus Radioisotopes; Rats; Rats, Inbred F344; Thigh | 1998 |
Potentiation of lonidamine and diazepam, two agents acting on mitochondria, in human glioblastoma treatment.
Topics: Animals; Anti-Anxiety Agents; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Division; Diazepam; Drug Synergism; Flow Cytometry; Fluorescence; Glioblastoma; Humans; Indazoles; Mice; Mice, Nude; Mitochondria; Thymidine; Treatment Outcome; Tumor Cells, Cultured | 1998 |
Effect of lonidamine on the utilization of 14C-labeled glucose by human astrocytoma cells.
Topics: Antineoplastic Agents; Brain Neoplasms; Carbon Radioisotopes; Deoxyglucose; Glioblastoma; Glucose; Glycolysis; Humans; Indazoles; Pentose Phosphate Pathway; Pyrazoles; Tumor Cells, Cultured | 1987 |