Compounds > lonidamine
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lonidamine and Astrocytoma, Grade IV

lonidamine has been researched along with Astrocytoma, Grade IV in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's2 (33.33)18.2507
2000's1 (16.67)29.6817
2010's1 (16.67)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Dong, Y; Huang, X; Ma, N; Qiao, H; Ren, K; Song, Y; Yang, L; Ye, Y; Yuan, Z; Zhang, D1
Castigli, E; Corazzi, L; Corcelli, A; Cristina Marchetti, M; Davidescu, M; Macchioni, L; Migliorati, G; Roberti, R; Scaramozzino, G; Vitale, R1
Andrieu, JM; Banu, E; Carpentier, A; Celerier, D; Delattre, JY; Dutrillaux, B; Fauchon, F; Oudard, S; Poupon, MF1
Biroccio, A; D'Angelo, C; Del Bufalo, D; Laudonio, N; Sacchi, A; Soddu, S; Zupi, G1
Bourgeois, Y; Bras Gonçalves, R; Dutrillaux, B; Miccoli, L; Oudard, S; Poirson-Bichat, F; Poupon, MF; Sureau, F1
Caputo, A; Del Carlo, C; Fanciulli, M; Floridi, A; Giorno, S; Laudonio, N; Paggi, MG; Silvestrini, B; Zupi, G1

Trials

1 trial(s) available for lonidamine and Astrocytoma, Grade IV

ArticleYear
Phase II study of lonidamine and diazepam in the treatment of recurrent glioblastoma multiforme.
    Journal of neuro-oncology, 2003, Volume: 63, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Diazepam; Female; Glioblastoma; Humans; Indazoles; Male; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Survival Rate

2003

Other Studies

5 other study(ies) available for lonidamine and Astrocytoma, Grade IV

ArticleYear
Mitochondria-Targeting Pyroptosis Amplifier of Lonidamine-Modified Black Phosphorus Nanosheets for Glioblastoma Treatments.
    ACS applied materials & interfaces, 2023, Jun-07, Volume: 15, Issue:22

    Topics: Animals; Glioblastoma; Mice; Mitochondria; Phosphorus; Pyroptosis; Tumor Microenvironment

2023
The energy blockers bromopyruvate and lonidamine lead GL15 glioblastoma cells to death by different p53-dependent routes.
    Scientific reports, 2015, Sep-21, Volume: 5

    Topics: Apoptosis; Autophagy; Cell Line, Tumor; Energy Metabolism; Enzyme Inhibitors; Glioblastoma; Humans; Indazoles; Mitochondria; Pyruvates; Tumor Suppressor Protein p53

2015
Lonidamine induces apoptosis in drug-resistant cells independently of the p53 gene.
    The Journal of clinical investigation, 1996, Sep-01, Volume: 98, Issue:5

    Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Carmustine; Cell Line; Doxorubicin; Drug Resistance; Female; Glioblastoma; Humans; Indazoles; Treatment Failure; Tumor Cells, Cultured; Tumor Suppressor Protein p53

1996
Potentiation of lonidamine and diazepam, two agents acting on mitochondria, in human glioblastoma treatment.
    Journal of the National Cancer Institute, 1998, Sep-16, Volume: 90, Issue:18

    Topics: Animals; Anti-Anxiety Agents; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Division; Diazepam; Drug Synergism; Flow Cytometry; Fluorescence; Glioblastoma; Humans; Indazoles; Mice; Mice, Nude; Mitochondria; Thymidine; Treatment Outcome; Tumor Cells, Cultured

1998
Effect of lonidamine on the utilization of 14C-labeled glucose by human astrocytoma cells.
    Experimental and molecular pathology, 1987, Volume: 47, Issue:2

    Topics: Antineoplastic Agents; Brain Neoplasms; Carbon Radioisotopes; Deoxyglucose; Glioblastoma; Glucose; Glycolysis; Humans; Indazoles; Pentose Phosphate Pathway; Pyrazoles; Tumor Cells, Cultured

1987