lonafarnib has been researched along with Astrocytoma, Grade IV in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Edney, B; Kim, Y; Kondapaneni, RV; Nakod, PS; Rao, SS | 1 |
| Colman, H; Conrad, C; Gilbert, MR; Groves, M; Hsu, S; Kang, S; Levin, V; Liu, D; Liu, V; Puduvalli, V; Yuan, Y; Yung, WK; Yust-Katz, S | 1 |
| Glass, TL; Liu, TJ; Yung, WK | 1 |
| Feldkamp, MM; Guha, A; Lau, N; Roncari, L | 1 |
1 trial(s) available for lonafarnib and Astrocytoma, Grade IV
| Article | Year |
|---|---|
Phase 1/1b study of lonafarnib and temozolomide in patients with recurrent or temozolomide refractory glioblastoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Disease-Free Survival; Female; Glioblastoma; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Piperidines; Pyridines; Supratentorial Neoplasms; Temozolomide | 2013 |
3 other study(ies) available for lonafarnib and Astrocytoma, Grade IV
| Article | Year |
|---|---|
The impact of temozolomide and lonafarnib on the stemness marker expression of glioblastoma cells in multicellular spheroids.
Topics: Cell Line, Tumor; Dibenzocycloheptenes; Drug Resistance, Neoplasm; Endothelial Cells; Glioblastoma; Humans; Nestin; Piperidines; Pyridines; Spheroids, Cellular; Temozolomide; Tumor Microenvironment | 2022 |
Inhibition of cell growth in human glioblastoma cell lines by farnesyltransferase inhibitor SCH66336.
Topics: Alkyl and Aryl Transferases; Cell Division; Cell Survival; Enzyme Inhibitors; Farnesyltranstransferase; G2 Phase; Glioblastoma; Humans; Mitogen-Activated Protein Kinases; Piperidines; Pyridines; Tumor Cells, Cultured | 2000 |
Isotype-specific Ras.GTP-levels predict the efficacy of farnesyl transferase inhibitors against human astrocytomas regardless of Ras mutational status.
Topics: Alkyl and Aryl Transferases; Animals; Astrocytoma; Brain Neoplasms; Cell Division; Enzyme Inhibitors; Farnesyltranstransferase; Genes, ras; Glioblastoma; Guanosine Triphosphate; Humans; Immunohistochemistry; Mice; Mice, Inbred BALB C; Mice, Inbred NOD; Mice, Nude; Mice, SCID; Monomeric GTP-Binding Proteins; Mutation; Piperidines; Pyridines; ras Proteins; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2001 |