lonafarnib has been researched along with Acute Myelogenous Leukemia in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (83.33) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aguilar-Garrido, P; Balabasquer, M; Campillo, M; Cushman, I; Gajate, C; Gallardo, M; Gil-Ordóñez, A; López-Rodríguez, ML; Marcos-Ramiro, B; Marín-Ramos, NI; Martín-Fontecha, M; Medrano, FJ; Mollinedo, F; Ortega-Gutiérrez, S; Ortega-Nogales, FJ; Philips, MR; Romero, A; Torrecillas, IR | 1 |
| André, M; Bosly, A; Bron, D; Debusscher, L; El Housni, H; Martiat, P; Mineur, P; Ravoet, C; Robin, V; Soree, A | 1 |
| Bishop, WR; Nakajima, A; Ohyashiki, K; Sumi, M; Tauchi, T | 1 |
| Druker, BJ | 1 |
| Cortes, J | 1 |
| Elhamri, M; Thomas, X | 1 |
1 review(s) available for lonafarnib and Acute Myelogenous Leukemia
| Article | Year |
|---|---|
[Farnesyltransferase inhibitors: preliminary results in acute myeloid leukemia].
Topics: Alkyl and Aryl Transferases; Benzodiazepines; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Drug Resistance, Neoplasm; Enzyme Inhibitors; Farnesyltranstransferase; Humans; Imidazoles; Leukemia, Myeloid, Acute; Mitogen-Activated Protein Kinase 1; Myeloproliferative Disorders; Piperidines; Protein Prenylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyridines; Quinolones; ras Proteins; rho GTP-Binding Proteins | 2005 |
1 trial(s) available for lonafarnib and Acute Myelogenous Leukemia
| Article | Year |
|---|---|
Farnesyl transferase inhibitor (lonafarnib) in patients with myelodysplastic syndrome or secondary acute myeloid leukaemia: a phase II study.
Topics: Aged; Farnesyltranstransferase; Female; Gastrointestinal Diseases; Genes, ras; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Piperidines; Pyridines | 2008 |
4 other study(ies) available for lonafarnib and Acute Myelogenous Leukemia
| Article | Year |
|---|---|
A Potent Isoprenylcysteine Carboxylmethyltransferase (ICMT) Inhibitor Improves Survival in Ras-Driven Acute Myeloid Leukemia.
Topics: Alanine; Amides; Animals; Antineoplastic Agents; Apoptosis; Autophagy; Cell Line, Tumor; Enzyme Inhibitors; Humans; Leukemia, Myeloid, Acute; Mice; Protein Methyltransferases; Xenograft Model Antitumor Assays | 2019 |
Efficacy of SCH66336, a farnesyl transferase inhibitor, in conjunction with imatinib against BCR-ABL-positive cells.
Topics: Alkyl and Aryl Transferases; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzamides; Cell Division; Colony-Forming Units Assay; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Farnesyltranstransferase; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Interleukin-3; Leukemia, Myeloid, Acute; Piperazines; Piperidines; Protein-Tyrosine Kinases; Pyridines; Pyrimidines; Transfection; Treatment Outcome; Tumor Cells, Cultured | 2003 |
Overcoming resistance to imatinib by combining targeted agents.
Topics: Alkyl and Aryl Transferases; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzamides; Cell Division; Drug Resistance, Neoplasm; Enzyme Inhibitors; Farnesyltranstransferase; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Leukemia, Myeloid, Acute; Piperazines; Piperidines; Pyridines; Pyrimidines | 2003 |
Farnesyltransferase inhibitors in acute myeloid leukemia and myelodysplastic syndromes.
Topics: Alkyl and Aryl Transferases; Antineoplastic Agents; Benzodiazepines; Clinical Trials as Topic; Farnesyltranstransferase; Humans; Imidazoles; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Piperidines; Pyridines; Quinolones | 2003 |