lomustine has been researched along with Spinal Cord Neoplasms in 8 studies
Spinal Cord Neoplasms: Benign and malignant neoplasms which occur within the substance of the spinal cord (intramedullary neoplasms) or in the space between the dura and spinal cord (intradural extramedullary neoplasms). The majority of intramedullary spinal tumors are primary CNS neoplasms including ASTROCYTOMA; EPENDYMOMA; and LIPOMA. Intramedullary neoplasms are often associated with SYRINGOMYELIA. The most frequent histologic types of intradural-extramedullary tumors are MENINGIOMA and NEUROFIBROMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twenty-one patients with recurrent malignant central nervous system gliomas were treated with a combination of 5-fluorouracil, CCNU, hydroxyurea, and 6-mercaptopurine." | 7.67 | Treatment of recurrent brain stem gliomas and other central nervous system tumors with 5-fluorouracil, CCNU, hydroxyurea, and 6-mercaptopurine. ( Edwards, MS; Fulton, D; Levin, V; Prados, M; Rodriguez, LA; Silver, P, 1988) |
| "Twenty-one patients with recurrent malignant central nervous system gliomas were treated with a combination of 5-fluorouracil, CCNU, hydroxyurea, and 6-mercaptopurine." | 3.67 | Treatment of recurrent brain stem gliomas and other central nervous system tumors with 5-fluorouracil, CCNU, hydroxyurea, and 6-mercaptopurine. ( Edwards, MS; Fulton, D; Levin, V; Prados, M; Rodriguez, LA; Silver, P, 1988) |
| "Forty ependymomas were grade I and 13 were grades II to IV (in five patients there was insufficient material for grading)." | 1.28 | Postoperative radiotherapy in the management of spinal cord ependymoma. ( Ashley, SE; Bell, BA; Bessell, EM; Bloom, HJ; Brada, M; Whitaker, SJ, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (62.50) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ater, JL | 1 |
| Zhou, T | 1 |
| Holmes, E | 1 |
| Mazewski, CM | 1 |
| Booth, TN | 1 |
| Freyer, DR | 1 |
| Lazarus, KH | 1 |
| Packer, RJ | 1 |
| Prados, M | 2 |
| Sposto, R | 1 |
| Vezina, G | 1 |
| Wisoff, JH | 1 |
| Pollack, IF | 1 |
| Henson, JW | 1 |
| Thornton, AF | 1 |
| Louis, DN | 1 |
| Ziegler, JL | 1 |
| Magrath, IT | 1 |
| Bluming, AZ | 1 |
| Whitaker, SJ | 1 |
| Bessell, EM | 1 |
| Ashley, SE | 1 |
| Bloom, HJ | 1 |
| Bell, BA | 1 |
| Brada, M | 1 |
| Rodriguez, LA | 1 |
| Fulton, D | 1 |
| Edwards, MS | 1 |
| Silver, P | 1 |
| Levin, V | 1 |
| Gershanovich, ML | 1 |
| Arkhipov, AI | 1 |
| Vilenskiĭ, BS | 1 |
| Mennel, HD | 1 |
| Hellwig, D | 1 |
| Simon, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Chemotherapy for Progressive Low Grade Astrocytoma in Children Less Than Ten Years Old[NCT00002944] | Phase 3 | 428 participants (Actual) | Interventional | 1997-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for lomustine and Spinal Cord Neoplasms
| Article | Year |
|---|---|
Randomized study of two chemotherapy regimens for treatment of low-grade glioma in young children: a report from the Children's Oncology Group.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Central Nervous System | 2012 |
7 other studies available for lomustine and Spinal Cord Neoplasms
| Article | Year |
|---|---|
Spinal cord astrocytoma: response to PCV chemotherapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Biopsy; Fatal Outcome; Humans; L | 2000 |
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 44-1978.
Topics: Astrocytoma; Carcinoma, Squamous Cell; Ependymoma; Female; Glioma; Hemangioma, Cavernous; Humans; Li | 1978 |
Management of Burkitt's lymphoma involving the central nervous system.
Topics: Antineoplastic Agents; Brain Neoplasms; Burkitt Lymphoma; Child; Cyclophosphamide; Cytarabine; Human | 1976 |
Postoperative radiotherapy in the management of spinal cord ependymoma.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Co | 1991 |
Treatment of recurrent brain stem gliomas and other central nervous system tumors with 5-fluorouracil, CCNU, hydroxyurea, and 6-mercaptopurine.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Brain Stem; Chil | 1988 |
[Use of nitrosourea derivatives in the treatment of patients with Hodgkin's disease with lesions of the central nervous system].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Drug Evaluation; | 1988 |
Chemotherapy in intracerebrally transplanted tumors induced with transplacental administration of ethylnitrosourea in rats.
Topics: Animals; Brain Neoplasms; Drug Administration Schedule; Ethylnitrosourea; Female; Lomustine; Methyln | 1986 |