Page last updated: 2024-10-30

lomustine and Pulmonary Fibrosis

lomustine has been researched along with Pulmonary Fibrosis in 9 studies

Pulmonary Fibrosis: A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death.

Research Excerpts

ExcerptRelevanceReference
"Diffuse pulmonary diseases seen in patients receiving chemotherapy have a wide variety of etiologies including infection, involvement with the underlying disease, injury from radiation or diagnostic agents, and toxicity from chemotherapeutic drugs."2.36Review: diagnosis of chemotherapy lung. ( Gamsu, G; Putman, CE; Sostman, HD, 1981)
"Necropsy identified severe diffuse pulmonary fibrosis and no signs of lymphoma."1.35Pulmonary fibrosis after high cumulative dose nitrosourea chemotherapy in a cat. ( Duda, L; Durham, AC; Skorupski, KA; Sørenmo, KU, 2008)
"Two patients treated for chronic myeloid leukemia with high doses of CCNU (1100 mg/m2 and 1240 mg/m2, respectively) developed a fatal pulmonary fibrosis."1.27Pulmonary fibrosis subsequent to high doses of CCNU for chronic myeloid leukemia. ( Bernaudin, JF; Cordonnier, C; Lange, F; Mital, P; Rochant, H; Vernant, JP, 1983)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19906 (66.67)18.7374
1990's2 (22.22)18.2507
2000's1 (11.11)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Skorupski, KA1
Durham, AC1
Duda, L1
Sørenmo, KU1
Sostman, HD1
Putman, CE1
Gamsu, G1
Cordonnier, C1
Vernant, JP1
Mital, P1
Lange, F1
Bernaudin, JF1
Rochant, H1
Vats, TS1
Trueworthy, RC1
Langston, CM1
Massin, F1
Coudert, B1
Foucher, P1
Lombard, JN1
Reybet-Degat, O1
Jeannin, L1
Camus, P1
Twohig, KJ1
Matthay, RA1
Brooks, BJ1
Seifter, EJ1
Walsh, TE1
Lichter, AS1
Bunn, PA1
Zabell, A1
Johnston-Early, A1
Edison, M1
Makuch, RW1
Cohen, MH1
Phillips, GL1
Reece, DE1
Tucci, E1
Verdiani, P1
Di Carlo, S1
Sforza, V1

Reviews

4 reviews available for lomustine and Pulmonary Fibrosis

ArticleYear
Review: diagnosis of chemotherapy lung.
    AJR. American journal of roentgenology, 1981, Volume: 136, Issue:1

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Bleomycin; Busulfan; Carmustine; Cy

1981
[Nitrosourea-induced lung diseases].
    Revue des maladies respiratoires, 1992, Volume: 9, Issue:6

    Topics: Adult; Brain Neoplasms; Carmustine; Child; Drug Therapy, Combination; Female; Humans; Iatrogenic Dis

1992
Pulmonary effects of cytotoxic agents other than bleomycin.
    Clinics in chest medicine, 1990, Volume: 11, Issue:1

    Topics: Antineoplastic Agents; Bleomycin; Busulfan; Carmustine; Cyclophosphamide; Humans; Lomustine; Methotr

1990
Clinical studies of autologous bone marrow transplantation in Hodgkin's disease.
    Clinics in haematology, 1986, Volume: 15, Issue:1

    Topics: Alkylating Agents; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marro

1986

Trials

1 trial available for lomustine and Pulmonary Fibrosis

ArticleYear
Pulmonary toxicity with combined modality therapy for limited stage small-cell lung cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1986, Volume: 4, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modalit

1986

Other Studies

4 other studies available for lomustine and Pulmonary Fibrosis

ArticleYear
Pulmonary fibrosis after high cumulative dose nitrosourea chemotherapy in a cat.
    Veterinary and comparative oncology, 2008, Volume: 6, Issue:2

    Topics: Adrenal Cortex Hormones; Animals; Antineoplastic Agents, Alkylating; Cat Diseases; Cats; Fatal Outco

2008
Pulmonary fibrosis subsequent to high doses of CCNU for chronic myeloid leukemia.
    Cancer, 1983, May-15, Volume: 51, Issue:10

    Topics: Adult; Carmustine; Female; Humans; Leukemia, Myeloid; Lomustine; Male; Nitrosourea Compounds; Pulmon

1983
Pulmonary fibrosis associated with lomustine (CCNU): a case report.
    Cancer treatment reports, 1982, Volume: 66, Issue:10

    Topics: Astrocytoma; Brain; Brain Neoplasms; Child; Humans; Lomustine; Male; Nitrosourea Compounds; Pulmonar

1982
Lomustine (CCNU)-induced pulmonary fibrosis.
    Tumori, 1986, Feb-28, Volume: 72, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Lomustine; Male; Pulmon

1986