Page last updated: 2024-10-30

lomustine and Pancreatic Neoplasms

lomustine has been researched along with Pancreatic Neoplasms in 15 studies

Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).

Research Excerpts

ExcerptRelevanceReference
"Forty-seven patients with unoperable pancreatic cancer were included in a controlled, prospective study of combination chemotherapy."2.65Treatment of unresectable pancreatic carcinoma with 5-fluorouracil, vincristine, and CCNU. ( Andrén-Sandberg, A; Holmberg, JT; Ihse, I, 1983)
"Although advanced gastrointestinal cancer is the most commonplace problem encountered by the medical oncologist, this group of diseases has proved exceedingly resistant to past chemotherapy efforts."1.25Clinical management of advanced gastrointestinal cancer. ( Moertel, CG, 1975)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-199013 (86.67)18.7374
1990's2 (13.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rhodes, EG1
Boesen, EA1
Corringham, RE1
Matthews, KB1
Tuddenham, EG1
Kernoff, PB1
Andrén-Sandberg, A1
Holmberg, JT1
Ihse, I1
Frey, C1
Twomey, P1
Keehn, R1
Elliott, D1
Higgins, G1
Vaughn, CB1
Chapman, JL1
Garland, M1
Pederson, B1
Demitrish, MM1
Chinn, B1
Ward, D1
Brady, PR1
Kokkinakis, DM1
Ahmed, MM1
Delgado, R1
Fruitwala, MM1
Mohiuddin, M3
Albores-Saavedra, J1
Moertel, CG5
Engstrom, P1
Lavin, PT1
Gelber, RD1
Carbone, PP1
Hill, GJ1
Johnson, RO1
Metter, G1
Wilson, WL1
Davis, HL1
Grage, T1
Fletcher, WS1
Golomb, FM1
Cruz, AB1
Rosato, F1
Barbot, D2
Schuricht, A1
Biermann, W2
Cantor, R1
Zimmermann, K1
Rapp, T1
Binder, J1
Frölich, J1
Bode, JC1
Khandekar, JD1
Sriratana, P1
Cantor, RJ1
Weiss, SM1
Rosato, FE1

Reviews

1 review available for lomustine and Pancreatic Neoplasms

ArticleYear
Chemotherapy of gastrointestinal cancer.
    The New England journal of medicine, 1978, Nov-09, Volume: 299, Issue:19

    Topics: Apudoma; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Gastrointestinal Neoplasms; Hum

1978

Trials

5 trials available for lomustine and Pancreatic Neoplasms

ArticleYear
Treatment of unresectable pancreatic carcinoma with 5-fluorouracil, vincristine, and CCNU.
    Scandinavian journal of gastroenterology, 1983, Volume: 18, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Female; Fluorouracil

1983
Randomized study of 5-FU and CCNU in pancreatic cancer: report of the Veterans Administration Surgical Adjuvant Cancer Chemotherapy Study Group.
    Cancer, 1981, Jan-01, Volume: 47, Issue:1

    Topics: Adenocarcinoma; Aged; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combinat

1981
The efficacy of 5-fluorouracil, mitomycin C, and methyl CCNU in advanced gastrointestinal malignancy.
    Oncology, 1981, Volume: 38, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Clinical Trials as Topic; Colonic Neoplasms; Dru

1981
Chemotherapy of gastric and pancreatic carcinoma: a controlled evaluation of combinations of 5-fluorouracil with nitrosoureas and "lactones".
    Surgery, 1979, Volume: 85, Issue:5

    Topics: Adenocarcinoma; Antineoplastic Agents; Drug Therapy, Combination; Fluorouracil; Humans; Lomustine; N

1979
Combined modality treatment of localized unresectable adenocarcinoma of the pancreas.
    International journal of radiation oncology, biology, physics, 1988, Volume: 14, Issue:1

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Clinical Trials as To

1988

Other Studies

9 other studies available for lomustine and Pancreatic Neoplasms

ArticleYear
Disappearance of antibodies to Factor VIII in a patient with acquired haemophilia and carcinoma of the pancreas during cytotoxic therapy with fluorouracil and CCNU.
    Thrombosis and haemostasis, 1984, Oct-31, Volume: 52, Issue:2

    Topics: Adenocarcinoma; Aged; Antibodies; Antineoplastic Combined Chemotherapy Protocols; Factor VIII; Femal

1984
Role of O6-methylguanine-DNA methyltransferase in the resistance of pancreatic tumors to DNA alkylating agents.
    Cancer research, 1997, Dec-01, Volume: 57, Issue:23

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents, Alkylating; Apoptosis; Carmustine; Cell Survival

1997
Clinical management of advanced gastrointestinal cancer.
    Cancer, 1975, Volume: 36, Issue:2

    Topics: Adenoma, Islet Cell; Carcinoma, Hepatocellular; Carmustine; Colonic Neoplasms; Cytarabine; Drug Ther

1975
Walter Hubert lecture Chemotherapy of upper gastrointestinal carcinoma.
    British journal of cancer, 1976, Volume: 34, Issue:3

    Topics: Adenoma, Islet Cell; Antineoplastic Agents; Carcinoid Tumor; Carcinoma, Hepatocellular; Carcinoma, S

1976
Multimodal surgical adjuvant therapy for a broad spectrum of tumors in humans.?
    Surgery, gynecology & obstetrics, 1976, Volume: 142, Issue:6

    Topics: Adult; Altretamine; Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Carmustine; Colonic Neo

1976
Gastrointestinal cancer. Treatment with fluorouracil-nitrosourea combinations.
    JAMA, 1976, May-10, Volume: 235, Issue:19

    Topics: Carmustine; Colonic Neoplasms; Drug Therapy, Combination; Female; Fluorouracil; Gastrointestinal Neo

1976
Long-term results of combined modality treatment with I-125 implantation for carcinoma of the pancreas.
    International journal of radiation oncology, biology, physics, 1992, Volume: 23, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Combined

1992
[Vipoma. 9-year observations using currently available therapy methods].
    Deutsche medizinische Wochenschrift (1946), 1986, Feb-21, Volume: 111, Issue:8

    Topics: Adenoma, Islet Cell; Antineoplastic Combined Chemotherapy Protocols; Drug Therapy, Combination; Fluo

1986
Response of glucagonoma syndrome to lomustine.
    Cancer treatment reports, 1986, Volume: 70, Issue:3

    Topics: Adenoma, Islet Cell; Glucagon; Glucagonoma; Humans; Lomustine; Male; Pancreatic Neoplasms

1986