Page last updated: 2024-10-30

lomustine and Ovarian Neoplasms

lomustine has been researched along with Ovarian Neoplasms in 7 studies

Ovarian Neoplasms: Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.

Research Excerpts

ExcerptRelevanceReference
"Thrombocytopenia was the primary toxic reaction."2.64A clinical trial of CCNU (1-(2 chloroethyl)-3-cyclohexyl-1-nitrosourea) (NSC 79037) in advanced ovarian carcinoma. ( Fletcher, WS; McConnell, DB; Merhoff, GC; Moseley, HS; Sasaki, TM, 1975)
"A new therapeutic strategy for advanced ovarian cancer is to administer ultra-high doses of anticancerous drugs, followed by peripheral blood stem cell transplantation (PBSCT) to recover normal marrow functions."1.29[Study on peripheral blood stem cells mobilized by different chemotherapies with granulocyte-colony stimulating factor in ovarian cancer]. ( Chiba, T; Fujioka, T; Hiura, M; Murakami, J; Nogawa, T; Shigemasa, K; Shimokawa, T; Yokoyama, T, 1995)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19904 (57.14)18.7374
1990's2 (28.57)18.2507
2000's1 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jones, AC1
Stratford, IJ1
Wilson, PA1
Peckham, MJ1
Hiura, M1
Murakami, J1
Shigemasa, K1
Fujioka, T1
Yokoyama, T1
Nogawa, T1
Chiba, T1
Shimokawa, T1
Aquilina, G1
Ceccotti, S1
Martinelli, S1
Soddu, S1
Crescenzi, M1
Branch, P1
Karran, P1
Bignami, M1
Omura, G1
DiSaia, P1
Blessing, J1
Boronow, R1
Hreshchyshyn, M1
Park, R1
Sasaki, TM1
McConnell, DB1
Moseley, HS1
Merhoff, GC1
Fletcher, WS1
Garrett, MJ1
Hughes, HJ1
Ryall, RD1
Krommer, K1
Keller, G1
Csaba, I1
Garadnay, B1
Göcze, P1

Trials

2 trials available for lomustine and Ovarian Neoplasms

ArticleYear
Chemotherapy for mustard-resistant ovarian adenocarcinoma: a randomized trial for CCNU and methyl-CCNU.
    Cancer treatment reports, 1977, Volume: 61, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Drug Administration Schedule; Drug Evaluation; Female; Humans; Lomustin

1977
A clinical trial of CCNU (1-(2 chloroethyl)-3-cyclohexyl-1-nitrosourea) (NSC 79037) in advanced ovarian carcinoma.
    Journal of surgical oncology, 1975, Volume: 7, Issue:5

    Topics: Alkylating Agents; Clinical Trials as Topic; Female; Humans; Lomustine; Nitrosourea Compounds; Ovari

1975

Other Studies

5 other studies available for lomustine and Ovarian Neoplasms

ArticleYear
In vitro cytotoxic drug sensitivity testing of human tumour xenografts grown as multicellular tumour spheroids.
    British journal of cancer, 1982, Volume: 46, Issue:6

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Aggregation; Cell Division; Cell Line; Cispla

1982
[Study on peripheral blood stem cells mobilized by different chemotherapies with granulocyte-colony stimulating factor in ovarian cancer].
    Nihon Sanka Fujinka Gakkai zasshi, 1995, Volume: 47, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Separation; Cisplatin; Cyclophosphamide; Epirub

1995
Mismatch repair and p53 independently affect sensitivity to N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosourea.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:2

    Topics: Adaptor Proteins, Signal Transducing; Amino Acid Substitution; Apoptosis; Base Pair Mismatch; bcl-2-

2000
CCNU in brain tumours.
    Clinical radiology, 1975, Volume: 26, Issue:2

    Topics: Adolescent; Adult; Brain Neoplasms; Bronchial Neoplasms; Cerebellar Neoplasms; Child, Preschool; Fem

1975
[Effect of 2 different forms of chemotherapy on remission in patients with advanced ovarian cancer].
    Zentralblatt fur Gynakologie, 1990, Volume: 112, Issue:17

    Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Doxorub

1990