lomustine has been researched along with Neuroectodermal Tumors, Primitive in 11 studies
Neuroectodermal Tumors, Primitive: A group of malignant tumors of the nervous system that feature primitive cells with elements of neuronal and/or glial differentiation. Use of this term is limited by some authors to central nervous system tumors and others include neoplasms of similar origin which arise extracranially (i.e., NEUROECTODERMAL TUMORS, PRIMITIVE, PERIPHERAL). This term is also occasionally used as a synonym for MEDULLOBLASTOMA. In general, these tumors arise in the first decade of life and tend to be highly malignant. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2059)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Supratentorial PNET (sPNET) are rare CNS tumors of embryonal origin arising in children and adults." | 2.74 | Non-pineal supratentorial primitive neuro-ectodermal tumors (sPNET) in teenagers and young adults: Time to reconsider cisplatin based chemotherapy after cranio-spinal irradiation? ( Biswas, S; Burke, A; Burnet, NG; Cherian, S; Earl, HM; Hatcher, H; Horan, G; Jefferies, S; Nicholson, J; Williams, D; Williams, M, 2009) |
| "Significant advances in the treatment of medulloblastoma and primitive neuroectodermal tumors have been made in the past three decades." | 2.42 | Medulloblastomas and central nervous system primitive neuroectodermal tumors. ( McLean, TW, 2003) |
| "Lomustine was administered, but 1 year after surgery, the dog exhibited cluster seizures and died." | 1.43 | Case of a miniature dachshund with a primitive neuroectodermal tumor confined to the forebrain region treated with a combination of surgery and chemotherapy. ( Matsunaga, S; Nakamoto, Y; Ozawa, T; Uchida, K; Yamada, A, 2016) |
| "In seven MB/PNET cell lines investigated, MGMT promoter methylation was detected only in D425 human MB cells as assayed by the qualitative methylation-specific PCR and the more quantitative pyrosequencing assay." | 1.37 | Expression of O⁶-methylguanine-DNA methyltransferase in childhood medulloblastoma. ( Arnold, L; Faoro, D; Gerber, NU; Grotzer, MA; Haybaeck, J; Hegi, M; Hürlimann, ML; Mittelbronn, M; Rutkowski, S; Sciuscio, D; Shalaby, T; von Bueren, AO, 2011) |
| "Identification of synchronous brain tumors prompted genetic testing for predisposition to malignancy." | 1.35 | De novo germline TP53 mutation presenting with synchronous malignancies of the central nervous system. ( Brat, DJ; Esiashvili, N; Janss, AJ; Schniederjan, MJ; Shehata, B, 2009) |
| "Supratentorial primitive neuroectodermal tumors (S-PNET) are rare and have a grim prognosis, frequently taking an aggressive course with local relapse and metastatic spread." | 1.33 | Supratentorial primitive neuroectodermal tumors (S-PNET) in children: A prospective experience with adjuvant intensive chemotherapy and hyperfractionated accelerated radiotherapy. ( Casanova, M; Cefalo, G; Collini, P; Ferrari, A; Fossati-Bellani, F; Gandola, L; Giangaspero, F; Luksch, R; Massimino, M; Meazza, C; Pignoli, E; Podda, M; Poggi, G; Polastri, D; Ravagnani, F; Simonetti, F; Spreafico, F; Terenziani, M, 2006) |
| "Much rarer are PNETs apparently arising in the leptomeninges." | 1.32 | Primary leptomeningeal primitive neuroectodermal tumor. ( Antunes, NL; Begemann, M; Dunkel, IJ; Lis, E; Lyden, D; Rosenblum, MK; Wolden, S, 2003) |
| "The outcome of a child with a primitive neuroectodermal tumors arising supratentorially (SPNET) is not well characterized and may differ from the outcome of a patient with a histologically similar cerebellar tumor (medulloblastoma [MB])." | 1.31 | Outcome for children with supratentorial primitive neuroectodermal tumors treated with surgery, radiation, and chemotherapy. ( Janss, AJ; Packer, RJ; Phillips, PC; Reddy, AT; Weiss, HL, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 6 (54.55) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Belcher, SM | 1 |
| Burton, CC | 1 |
| Cookman, CJ | 1 |
| Kirby, M | 1 |
| Miranda, GL | 1 |
| Saeed, FO | 1 |
| Wray, KE | 1 |
| Nakamoto, Y | 1 |
| Yamada, A | 1 |
| Uchida, K | 1 |
| Matsunaga, S | 1 |
| Ozawa, T | 1 |
| Biswas, S | 1 |
| Burke, A | 1 |
| Cherian, S | 1 |
| Williams, D | 1 |
| Nicholson, J | 1 |
| Horan, G | 1 |
| Jefferies, S | 1 |
| Williams, M | 1 |
| Earl, HM | 1 |
| Burnet, NG | 1 |
| Hatcher, H | 1 |
| Schniederjan, MJ | 1 |
| Shehata, B | 1 |
| Brat, DJ | 1 |
| Esiashvili, N | 1 |
| Janss, AJ | 2 |
| Faoro, D | 1 |
| von Bueren, AO | 1 |
| Shalaby, T | 1 |
| Sciuscio, D | 1 |
| Hürlimann, ML | 1 |
| Arnold, L | 1 |
| Gerber, NU | 1 |
| Haybaeck, J | 1 |
| Mittelbronn, M | 1 |
| Rutkowski, S | 1 |
| Hegi, M | 1 |
| Grotzer, MA | 1 |
| Begemann, M | 1 |
| Lyden, D | 1 |
| Rosenblum, MK | 1 |
| Lis, E | 1 |
| Wolden, S | 1 |
| Antunes, NL | 1 |
| Dunkel, IJ | 1 |
| McLean, TW | 1 |
| Massimino, M | 1 |
| Gandola, L | 1 |
| Spreafico, F | 1 |
| Luksch, R | 1 |
| Collini, P | 1 |
| Giangaspero, F | 1 |
| Simonetti, F | 1 |
| Casanova, M | 1 |
| Cefalo, G | 1 |
| Pignoli, E | 1 |
| Ferrari, A | 1 |
| Terenziani, M | 1 |
| Podda, M | 1 |
| Meazza, C | 1 |
| Polastri, D | 1 |
| Poggi, G | 1 |
| Ravagnani, F | 1 |
| Fossati-Bellani, F | 1 |
| Cohen, BH | 1 |
| Zeltzer, PM | 1 |
| Boyett, JM | 1 |
| Geyer, JR | 1 |
| Allen, JC | 1 |
| Finlay, JL | 1 |
| McGuire-Cullen, P | 1 |
| Milstein, JM | 1 |
| Rorke, LB | 2 |
| Stanley, P | 1 |
| Goldwein, JW | 1 |
| Radcliffe, J | 1 |
| Johnson, J | 1 |
| Moshang, T | 1 |
| Packer, RJ | 2 |
| Sutton, LN | 1 |
| D'Angio, GJ | 1 |
| Reddy, AT | 1 |
| Phillips, PC | 1 |
| Weiss, HL | 1 |
1 review available for lomustine and Neuroectodermal Tumors, Primitive
| Article | Year |
|---|---|
Medulloblastomas and central nervous system primitive neuroectodermal tumors.
Topics: Antineoplastic Agents; Central Nervous System Neoplasms; Cerebellar Neoplasms; Cisplatin; Cyclophosp | 2003 |
2 trials available for lomustine and Neuroectodermal Tumors, Primitive
| Article | Year |
|---|---|
Non-pineal supratentorial primitive neuro-ectodermal tumors (sPNET) in teenagers and young adults: Time to reconsider cisplatin based chemotherapy after cranio-spinal irradiation?
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Neoplasms; Child; Cisp | 2009 |
Prognostic factors and treatment results for supratentorial primitive neuroectodermal tumors in children using radiation and chemotherapy: a Childrens Cancer Group randomized trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child; Child, Preschool; Combined M | 1995 |
8 other studies available for lomustine and Neuroectodermal Tumors, Primitive
| Article | Year |
|---|---|
Estrogen and soy isoflavonoids decrease sensitivity of medulloblastoma and central nervous system primitive neuroectodermal tumor cells to chemotherapeutic cytotoxicity.
Topics: Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Cisplatin; Equol; Estradiol | 2017 |
Case of a miniature dachshund with a primitive neuroectodermal tumor confined to the forebrain region treated with a combination of surgery and chemotherapy.
Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dog Diseases | 2016 |
De novo germline TP53 mutation presenting with synchronous malignancies of the central nervous system.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma; Choroid Plex | 2009 |
Expression of O⁶-methylguanine-DNA methyltransferase in childhood medulloblastoma.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Cell Proliferation; C | 2011 |
Primary leptomeningeal primitive neuroectodermal tumor.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Combined Modality Therapy; Crani | 2003 |
Supratentorial primitive neuroectodermal tumors (S-PNET) in children: A prospective experience with adjuvant intensive chemotherapy and hyperfractionated accelerated radiotherapy.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Chemotherapy, Adjuvant; Chi | 2006 |
Updated results of a pilot study of low dose craniospinal irradiation plus chemotherapy for children under five with cerebellar primitive neuroectodermal tumors (medulloblastoma).
Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Neoplasms; Child, Preschool; | 1996 |
Outcome for children with supratentorial primitive neuroectodermal tumors treated with surgery, radiation, and chemotherapy.
Topics: Adolescent; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytoge | 2000 |