lomustine has been researched along with Nausea in 15 studies
Nausea: An unpleasant sensation in the stomach usually accompanied by the urge to vomit. Common causes are early pregnancy, sea and motion sickness, emotional stress, intense pain, food poisoning, and various enteroviruses.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thirty-seven consecutive patients with disseminated malignant melanoma and previously untreated with chemotherapy were randomly allocated to receive vindesine, cis-platinum, and etoposide (Regimen A) or vindesine, cis-platinum, and lomustine (Regimen B)." | 9.05 | Prospective randomized trial in advanced malignant melanoma with cis-platinum, vindesine, and etoposide vs. cis-platinum, vindesine, and lomustine. ( Bajetta, E; Bonadonna, G; Buzzoni, R; Nava, M; Vaglini, M; Viviani, S, 1985) |
| "One hundred and six patients with advanced adenocarcinoma and large cell carcinoma of the lung with no prior chemotherapy were entered in a prospectively randomized trial comparing cyclophosphamide, doxorubicin, and cisplatin versus methotrexate, doxorubicin, cyclophosphamide, and lomustine." | 5.05 | Comparison of combination chemotherapy programs in advanced adenocarcinoma-large cell carcinoma of the lung: a North Central Cancer Treatment Group study. ( Cullinan, S; Eagan, RT; Elliott, T; Etzell, P; Fleming, TR; Krook, JE; Pfeifle, D, 1984) |
| "Thirty-seven consecutive patients with disseminated malignant melanoma and previously untreated with chemotherapy were randomly allocated to receive vindesine, cis-platinum, and etoposide (Regimen A) or vindesine, cis-platinum, and lomustine (Regimen B)." | 5.05 | Prospective randomized trial in advanced malignant melanoma with cis-platinum, vindesine, and etoposide vs. cis-platinum, vindesine, and lomustine. ( Bajetta, E; Bonadonna, G; Buzzoni, R; Nava, M; Vaglini, M; Viviani, S, 1985) |
| "Forty-three patients with inoperable or recurring malignant gliomas, and 30 patients with multiple recurring brain metastases were treated with a combination of Adriamycin (45 mg/m2) and 4-dimethyl-epipodophyllotoxin D-thenylidene (VM 26) (60 mg/m2 for 2 days) with 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) (60 mg/m2 for 2 days)." | 3.65 | Treatment of malignant gliomas and brain metastases in adults with a combination of adriamycin, VM 26, and CCNU. Results of a phase II trail. ( Gauthier, H; Huguenin, P; Lheritier, J; Mathe, G; Morin, P; Parrot, R; Poisson, M; Pouillart, P; Thy, TH, 1976) |
| "Lomustine is a commercially available chloroethyl nitrosourea compound whose antitumor activity in vitro and in animal tumor models exceeds its activity in humans." | 2.67 | A phase I trial of weekly lomustine in patients with advanced cancer. ( Benjamin, RS; Gorski, CC; Koller, CA; Legha, SS; Papadopoulos, NE; Plager, C, 1994) |
| "Thirty-five patients with advanced breast cancer refractory to initial chemotherapy were randomized to receive two-drug doxorubicin-CCNU or three-drug doxorubicin-CCNU-vincristine (VCR) treatment." | 2.65 | Doxorubicin and CCNU with or without vincristine in patients with advanced refractory breast cancer. A randomized trial. ( Bateman, JR; Block, JB; Chlebowski, RT; Pugh, R; Weiner, JM, 1983) |
| " The dosage of CCNU was 100 mg/m2 p." | 2.65 | The superiority of CCNU in the treatment of advanced Hodgkin's disease: Cancer and Leukemia Group B Study. ( Brunner, K; Cuttner, J; Falkson, G; Hansen, HH; Holland, JF; Nissen, NI; Pajak, TF; Selawry, OS; Spurr, CL, 1981) |
| "It is an effective drug in the treatment of malignant melanoma with better response rates in women than in men." | 2.64 | Phase I evaluation of DTIC (NSC-45388) and other studies in malignant melanoma in the Central Oncology Group. ( Hill, G; Johnson, RO; Krementz, E; Metter, G; Wilson, W, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (93.33) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Diggs, CH | 1 |
| Wiernik, PH | 1 |
| Sutherland, JC | 1 |
| Krook, JE | 1 |
| Fleming, TR | 1 |
| Eagan, RT | 1 |
| Cullinan, S | 1 |
| Pfeifle, D | 1 |
| Elliott, T | 1 |
| Etzell, P | 1 |
| Chlebowski, RT | 2 |
| Pugh, R | 1 |
| Weiner, JM | 1 |
| Block, JB | 2 |
| Bateman, JR | 2 |
| Whitehead, RP | 1 |
| Rosenbaum, PR | 1 |
| Carbone, PP | 1 |
| Hansen, HH | 1 |
| Selawry, OS | 1 |
| Pajak, TF | 2 |
| Spurr, CL | 1 |
| Falkson, G | 1 |
| Brunner, K | 1 |
| Cuttner, J | 1 |
| Nissen, NI | 1 |
| Holland, JF | 1 |
| Gagliano, RG | 1 |
| Panettiere, FJ | 1 |
| Haas, CD | 1 |
| Baker, L | 1 |
| Hewlett, J | 1 |
| Stuckey, WJ | 1 |
| O'Bryan, RM | 1 |
| Bottomley, R | 1 |
| Heilburn, LK | 1 |
| Koller, CA | 1 |
| Gorski, CC | 1 |
| Benjamin, RS | 1 |
| Legha, SS | 1 |
| Papadopoulos, NE | 1 |
| Plager, C | 1 |
| Reagan, TJ | 1 |
| Bisel, HF | 1 |
| Childs, DS | 1 |
| Layton, DD | 1 |
| Rhoton, AL | 1 |
| Taylor, WF | 1 |
| Stolinsky, DC | 1 |
| Bull, FE | 1 |
| Johnson, RO | 1 |
| Metter, G | 1 |
| Wilson, W | 1 |
| Hill, G | 1 |
| Krementz, E | 1 |
| Wasserman, TH | 1 |
| Pouillart, P | 1 |
| Mathe, G | 1 |
| Thy, TH | 1 |
| Lheritier, J | 1 |
| Poisson, M | 1 |
| Huguenin, P | 1 |
| Gauthier, H | 1 |
| Morin, P | 1 |
| Parrot, R | 1 |
| Page, JP | 1 |
| Levi, JA | 1 |
| Woods, RL | 1 |
| Tattersall, MN | 1 |
| Fox, RM | 1 |
| Coates, AS | 1 |
| Bajetta, E | 1 |
| Buzzoni, R | 1 |
| Viviani, S | 1 |
| Vaglini, M | 1 |
| Nava, M | 1 |
| Bonadonna, G | 1 |
| Chlebowski, JS | 1 |
| Herrold, J | 1 |
| Richardson, B | 1 |
| Ali, I | 1 |
| Oktay, E | 1 |
10 trials available for lomustine and Nausea
| Article | Year |
|---|---|
Treatment of advanced untreated Hodgkin's disease with SCAB--an alternative to MOPP.
Topics: Adult; Bleomycin; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Hodg | 1981 |
Comparison of combination chemotherapy programs in advanced adenocarcinoma-large cell carcinoma of the lung: a North Central Cancer Treatment Group study.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; | 1984 |
Doxorubicin and CCNU with or without vincristine in patients with advanced refractory breast cancer. A randomized trial.
Topics: Breast Neoplasms; Clinical Trials as Topic; Doxorubicin; Drug Therapy, Combination; Female; Humans; | 1983 |
The superiority of CCNU in the treatment of advanced Hodgkin's disease: Cancer and Leukemia Group B Study.
Topics: Adult; Carmustine; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Administration S | 1981 |
A phase I trial of weekly lomustine in patients with advanced cancer.
Topics: Administration, Oral; Adult; Aged; Capsules; Carcinoma, Renal Cell; Drug Administration Schedule; Dr | 1994 |
Controlled study of CCNU and radiation therapy in malignant astrocytoma.
Topics: Adult; Aged; Brain Neoplasms; Digestive System; Drug Evaluation; Glioblastoma; Hematopoiesis; Humans | 1976 |
Phase I evaluation of DTIC (NSC-45388) and other studies in malignant melanoma in the Central Oncology Group.
Topics: Carmustine; Clinical Trials as Topic; Dacarbazine; Drug Evaluation; Drug Therapy, Combination; Femal | 1976 |
Randomized trial of combination chemotherapy in hormone-resistant metastatic prostate carcinoma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cyclophosphamide; Do | 1985 |
Prospective randomized trial in advanced malignant melanoma with cis-platinum, vindesine, and etoposide vs. cis-platinum, vindesine, and lomustine.
Topics: Adult; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic | 1985 |
Doxorubicin, cyclophosphamide, CCNU, and vincristine with or without cisplatinum in non-small cell lung cancer.
Topics: Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Carcinoma; Cisplati | 1985 |
5 other studies available for lomustine and Nausea
| Article | Year |
|---|---|
Cisplatin, doxorubicin, cyclophosphamide, lomustine, and vincristine (PACCO) in the treatment of non-small cell bronchogenic carcinoma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Bronchogenic; Cisplatin; Cyclophosp | 1984 |
Evaluation of beta-2'-deoxythioguanosine combined with methyl-CCNU or mitomycin in advanced colorectal cancer. A Southwest Oncology Group study.
Topics: Adenocarcinoma; Colonic Neoplasms; Deoxyguanosine; Drug Evaluation; Drug Therapy, Combination; Human | 1981 |
Trial of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU; NSC-79037) in advanced bronchogenic carcinoma 1,2,3.
Topics: Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Carcinoma, Bronchogenic; Carcinoma, Small Cell; | 1975 |
The nitrosoureas: an outline of clinical schedules and toxic effects.
Topics: Administration, Oral; Bone Marrow; Capsules; Carmustine; Humans; Injections, Intravenous; Lomustine; | 1976 |
Treatment of malignant gliomas and brain metastases in adults with a combination of adriamycin, VM 26, and CCNU. Results of a phase II trail.
Topics: Adult; Aged; Brain Neoplasms; Doxorubicin; Drug Therapy, Combination; Drug Tolerance; Female; Glioma | 1976 |