lomustine has been researched along with Lymphoma, Non-Hodgkin in 34 studies
Lymphoma, Non-Hodgkin: Any of a group of malignant tumors of lymphoid tissue that differ from HODGKIN DISEASE, being more heterogeneous with respect to malignant cell lineage, clinical course, prognosis, and therapy. The only common feature among these tumors is the absence of giant REED-STERNBERG CELLS, a characteristic of Hodgkin's disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To improve survival of elderly patients with primary central nervous system lymphoma (PCNSL), we conducted a phase II study with high-dose methotrexate (MTX) combined with procarbazine and CCNU." | 2.74 | High-dose methotrexate combined with procarbazine and CCNU for primary CNS lymphoma in the elderly: results of a prospective pilot and phase II study. ( Deckert, M; Feuerhake, F; Finke, J; Ihorst, G; Illerhaus, G; Marks, R; Müller, F; Ostertag, C, 2009) |
| "A decreased incidence of interstitial pneumonitis as well as a possible benefit in efficacy has been reported with lomustine (CCNU) compared to BCNU in the standard dose setting." | 2.70 | Efficacy and toxicity of a CCNU-containing high-dose chemotherapy regimen followed by autologous hematopoietic cell transplantation in relapsed or refractory Hodgkin's disease. ( Blume, KG; Chao, NS; Horning, SJ; Johnston, LJ; Long, GD; Negrin, RS; Shizuru, JA; Stockerl-Goldstein, KE; Stuart, MJ; Wong, RM, 2001) |
| "Neutropenia was documented in 20 dogs (57%): 12 grade I to II, 8 grade III to IV." | 1.48 | Evaluation of a multi-agent chemotherapy protocol combining lomustine, procarbazine and prednisolone (LPP) for the treatment of relapsed canine non-Hodgkin high-grade lymphomas. ( Amores-Fuster, I; Blackwood, L; Finotello, R; Harper, A; Killick, DR; Maddox, TW; Mason, SL; Tanis, JB, 2018) |
| "Ninety-two patients with Hodgkin lymphoma and 47 with non-Hodgkin lymphoma were enrolled." | 1.43 | LACE versus BEAM conditioning in relapsed and refractory lymphoma transplant: retrospective multicenter analysis of toxicity and efficacy. ( Gore, A; Gupta, A; Jain, R; Jeevangi, N; Kannan, S; Khattry, N; Nair, R; Saikia, T; Thippeswamy, R, 2016) |
| "SHR mice with intracranial transplanted lymphosarcoma LIO-1 received a single intraperitoneal gemcitabine injection in maximal tolerated dose of 25 mg/kg or single maximal tolerated oral dose of lomustine, 50 mg/kg." | 1.38 | [Combined effect of gemcitabine and lomustine in mice with intracranial transplanted lymphosarcoma LIO-1]. ( Filatova, LV; Gershanovich, ML; Latinova, DKh; Semiglazova, TIu; Stukov, AN; Tarasenkova, AA; Vershinina, SF; Zargarova, NI, 2012) |
| " Data were analysed using noncompartmental pharmacokinetic methods." | 1.29 | Pharmacokinetics of high-dose oral CCNU in bone marrow transplant patients. ( Blaschke, TF; Chao, NJ; Kastrissios, H, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (14.71) | 18.7374 |
| 1990's | 14 (41.18) | 18.2507 |
| 2000's | 8 (23.53) | 29.6817 |
| 2010's | 6 (17.65) | 24.3611 |
| 2020's | 1 (2.94) | 2.80 |
| Authors | Studies |
|---|---|
| Russler-Germain, DA | 1 |
| Watkins, MP | 1 |
| Bartlett, NL | 1 |
| Tanis, JB | 1 |
| Mason, SL | 1 |
| Maddox, TW | 1 |
| Blackwood, L | 1 |
| Killick, DR | 1 |
| Amores-Fuster, I | 1 |
| Harper, A | 1 |
| Finotello, R | 1 |
| Khattry, N | 1 |
| Gupta, A | 1 |
| Jain, R | 1 |
| Gore, A | 1 |
| Thippeswamy, R | 1 |
| Jeevangi, N | 1 |
| Kannan, S | 1 |
| Nair, R | 1 |
| Saikia, T | 1 |
| Illerhaus, G | 2 |
| Marks, R | 1 |
| Müller, F | 1 |
| Ihorst, G | 2 |
| Feuerhake, F | 1 |
| Deckert, M | 1 |
| Ostertag, C | 1 |
| Finke, J | 2 |
| Mwanda, WO | 1 |
| Orem, J | 1 |
| Fu, P | 1 |
| Banura, C | 1 |
| Kakembo, J | 1 |
| Onyango, CA | 1 |
| Ness, A | 1 |
| Reynolds, S | 1 |
| Johnson, JL | 1 |
| Subbiah, V | 1 |
| Bako, J | 1 |
| Wabinga, H | 1 |
| Abdallah, FK | 1 |
| Meyerson, HJ | 1 |
| Whalen, CC | 1 |
| Lederman, MM | 1 |
| Black, J | 1 |
| Ayers, LW | 1 |
| Katongole-Mbidde, E | 1 |
| Remick, SC | 2 |
| Fritsch, K | 1 |
| Kasenda, B | 1 |
| Hader, C | 1 |
| Nikkhah, G | 1 |
| Prinz, M | 1 |
| Haug, V | 1 |
| Haug, S | 1 |
| Stukov, AN | 2 |
| Tarasenkova, AA | 2 |
| Gershanovich, ML | 3 |
| Filatova, LV | 2 |
| Semiglazova, TIu | 2 |
| Latipova, DKh | 1 |
| Vershinina, SF | 2 |
| Latinova, DKh | 1 |
| Zargarova, NI | 1 |
| Hallack Neto, AE | 1 |
| Borges dos Santos, K | 1 |
| Atalla, A | 1 |
| Stewart, AJ | 1 |
| Southcott, BM | 1 |
| Musolino, A | 1 |
| Perrone, MA | 1 |
| Michiara, M | 1 |
| Delnevo, D | 1 |
| Franciosi, V | 1 |
| Di Blasio, B | 1 |
| Ceci, G | 1 |
| Camisa, R | 1 |
| Ardizzoni, A | 1 |
| Cocconi, G | 1 |
| Alexandrescu, DT | 1 |
| Karri, S | 1 |
| Wiernik, PH | 1 |
| Dutcher, JP | 1 |
| Rusk, A | 1 |
| Cozzi, E | 1 |
| Stebbins, M | 1 |
| Vail, D | 1 |
| Graham, J | 1 |
| Valli, V | 1 |
| Henkin, J | 1 |
| Sharpee, R | 1 |
| Khanna, C | 1 |
| Lishner, M | 1 |
| Slingerland, J | 1 |
| Theresa, C | 1 |
| Sutcliffe, SB | 1 |
| Sardaş, S | 1 |
| Erdoğan, F | 1 |
| Sardaş, OS | 1 |
| Cengel, M | 1 |
| Karakaya, AE | 1 |
| Da, WM | 1 |
| Zhong, JT | 1 |
| Liu, Y | 1 |
| Huang, YS | 1 |
| Bai, H | 1 |
| Wu, XX | 1 |
| Ou, YX | 1 |
| Wang, CB | 1 |
| Xu, SF | 1 |
| McSharry, JJ | 1 |
| Wolf, BC | 1 |
| Blanchard, CG | 1 |
| Eastman, AY | 1 |
| Wagner, H | 1 |
| Portuese, E | 1 |
| Wighton, T | 1 |
| Powell, D | 1 |
| Pearce, T | 1 |
| Sweetenham, JW | 1 |
| McKendrick, JJ | 1 |
| Mead, GM | 1 |
| Whitehouse, JM | 1 |
| Dorigo, A | 1 |
| Mansberg, R | 1 |
| Kwan, YL | 1 |
| Kastrissios, H | 1 |
| Chao, NJ | 1 |
| Blaschke, TF | 1 |
| Palmieri, G | 1 |
| Morabito, A | 1 |
| Rea, A | 1 |
| Biondi, E | 1 |
| Lauria, R | 1 |
| Matano, E | 1 |
| Pagliarulo, C | 1 |
| Montesarchio, V | 1 |
| Tagliaferri, P | 1 |
| Bianco, AR | 1 |
| Akimov, MA | 1 |
| Shamash, J | 1 |
| Walewski, J | 1 |
| Apostolidis, J | 1 |
| Wilson, AM | 1 |
| Foran, JM | 1 |
| Gupta, RK | 1 |
| Rohatiner, AZ | 1 |
| Kelsey, SM | 1 |
| Lister, TA | 1 |
| Stuart, MJ | 1 |
| Chao, NS | 1 |
| Horning, SJ | 1 |
| Wong, RM | 1 |
| Negrin, RS | 1 |
| Johnston, LJ | 1 |
| Shizuru, JA | 1 |
| Long, GD | 1 |
| Blume, KG | 1 |
| Stockerl-Goldstein, KE | 1 |
| Nissen, NI | 2 |
| Pajak, T | 1 |
| Glidewell, O | 2 |
| Blom, H | 1 |
| Flaherty, M | 1 |
| Hayes, D | 1 |
| McIntyre, R | 1 |
| Holland, JF | 2 |
| Maurice, P | 1 |
| Jacquillat, C | 1 |
| Silver, RT | 1 |
| Carey, R | 1 |
| Pas, AT | 1 |
| Cornell, CJ | 1 |
| Burningham, RA | 1 |
| Chamberlain, MC | 2 |
| Levin, VA | 2 |
| Fouillard, L | 1 |
| Gorin, NC | 1 |
| Laporte, JP | 1 |
| Douay, L | 1 |
| Lopez, M | 1 |
| Isnard, F | 1 |
| Jouet, JP | 1 |
| Walter, MP | 1 |
| Morel, P | 1 |
| Fenaux, P | 1 |
| Jackson, DV | 1 |
| Craig, JB | 1 |
| Spurr, CL | 1 |
| White, DR | 1 |
| Muss, HB | 1 |
| Cruz, JM | 1 |
| Richards, F | 1 |
| Powell, BL | 1 |
| Ruit, JB | 1 |
| Löwenberg, B | 1 |
| Hagenbeek, A | 1 |
| Verhoef, GE | 1 |
| Wielenga, JJ | 1 |
| Michiels, J | 1 |
| Sizoo, W | 1 |
| Domingo Albós, A | 1 |
| Callís, M | 1 |
| Juliá, A | 1 |
| Vilá, J | 1 |
| Zuazu, J | 1 |
| Puig, J | 1 |
| Petit, J | 1 |
| Fernández-Sevilla, A | 1 |
| Kindzel'skiĭ, LP | 1 |
| Gubareva, AA | 1 |
| Haioun, C | 1 |
| Kuentz, M | 1 |
| Jouault, H | 1 |
| Gaulard, P | 1 |
| Divine, M | 1 |
| Farcet, JP | 1 |
| Reyes, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Treatment of Patients Over 65 Years With Primary CNS Lymphoma: High-dose Methotrexate Combined With Chemo-immunotherapy Followed by Maintenance Therapy[NCT00989352] | Phase 2 | 56 participants (Anticipated) | Interventional | 2009-09-30 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for lomustine and Lymphoma, Non-Hodgkin
| Article | Year |
|---|---|
Overview of four clinical studies of chemotherapy for stage III and IV non-Hodgkin's lymphomas by the Cancer and Leukemia Group B.
Topics: Adult; Bleomycin; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Drug The | 1977 |
9 trials available for lomustine and Lymphoma, Non-Hodgkin
| Article | Year |
|---|---|
High-dose methotrexate combined with procarbazine and CCNU for primary CNS lymphoma in the elderly: results of a prospective pilot and phase II study.
Topics: Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Comb | 2009 |
Immunochemotherapy with rituximab, methotrexate, procarbazine, and lomustine for primary CNS lymphoma (PCNSL) in the elderly.
Topics: Age Factors; Aged; Aged, 80 and over; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combine | 2011 |
Cooperative activity of cytotoxic chemotherapy with antiangiogenic thrombospondin-I peptides, ABT-526 in pet dogs with relapsed lymphoma.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Disease Progressio | 2006 |
Tailored therapy for aggressive non-Hodgkin's lymphoma: results of a phase II study with a long-term follow-up.
Topics: Adolescent; Adult; Aged; Antidotes; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogen | 1998 |
Low-dose continuous chemotherapy (LBCMVD-56) for refractory and relapsing lymphoma.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; De | 2000 |
Efficacy and toxicity of a CCNU-containing high-dose chemotherapy regimen followed by autologous hematopoietic cell transplantation in relapsed or refractory Hodgkin's disease.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Pro | 2001 |
Overview of four clinical studies of chemotherapy for stage III and IV non-Hodgkin's lymphomas by the Cancer and Leukemia Group B.
Topics: Adult; Bleomycin; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Drug The | 1977 |
Comparison of methyl-CCNU and CCNU in patients with advanced forms of Hodgkin's disease, lymphosarcoma nad reticulum cell sarcoma.
Topics: Clinical Trials as Topic; Female; Hodgkin Disease; Humans; Leukopenia; Lomustine; Lymphoma, Non-Hodg | 1978 |
Vincristine infusion with CHOP-CCNU in diffuse large-cell lymphoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cyclophospham | 1990 |
25 other studies available for lomustine and Lymphoma, Non-Hodgkin
| Article | Year |
|---|---|
A forgotten friend: CCNU as palliative monotherapy in relapsed Hodgkin lymphoma.
Topics: Friends; Hodgkin Disease; Humans; Lomustine; Lymphoma, Non-Hodgkin; Palliative Care | 2021 |
Evaluation of a multi-agent chemotherapy protocol combining lomustine, procarbazine and prednisolone (LPP) for the treatment of relapsed canine non-Hodgkin high-grade lymphomas.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Dog Diseases; Dogs; Female; Lomustine; Lymp | 2018 |
LACE versus BEAM conditioning in relapsed and refractory lymphoma transplant: retrospective multicenter analysis of toxicity and efficacy.
Topics: Adolescent; Adult; Autografts; Carmustine; Child; Child, Preschool; Cohort Studies; Cyclophosphamide | 2016 |
Dose-modified oral chemotherapy in the treatment of AIDS-related non-Hodgkin's lymphoma in East Africa.
Topics: Administration, Oral; Adolescent; Adult; Africa South of the Sahara; Antineoplastic Combined Chemoth | 2009 |
[Investigation of gemcitabine plus lomustine treatment in mice with transplantable lymphosarcoma LIO-1].
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined | 2011 |
[Combined effect of gemcitabine and lomustine in mice with intracranial transplanted lymphosarcoma LIO-1].
Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; A | 2012 |
Modified BEAM conditioning regimen in patients with Hodgkin and non-Hodgkin lymphomas.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Hematopoietic Stem Cell Trans | 2012 |
Coeliac disease following high-dose chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Celiac Disease; Cisplatin; Cyclophosphami | 2002 |
Lomustine (chloroethylnitrosourea [CCNU]), ifosfamide, bleomycin, vincristine, and cisplatin (CIBO-P) is an effective regimen for patients with poor prognostic refractory or multiple disease recurrent aggressive non-Hodgkin lymphoma.
Topics: Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic A | 2005 |
Mitoxantrone, vinblastine and CCNU: long-term follow-up of patients treated for advanced and poor-prognosis Hodgkin's disease.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Female; Follow-Up Studies; Humans; Lomustine; Lympho | 2006 |
The response of diffuse large cell and other intermediate grade non-Hodgkin's lymphomas to adriamycin containing combination chemotherapy.
Topics: Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Cyclophosp | 1994 |
Sister chromatid exchange studies for monitoring DNA damage in lymphocytes of malignant lymphoma patients under cytostatic therapy.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosph | 1994 |
Prolonged disease-free survival after ablative chemoradiotherapy and autologous bone marrow transplantation in adult malignant lymphoma.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Purging; Bone Marrow | 1993 |
Novel oral combination chemotherapy in the treatment of intermediate-grade and high-grade AIDS-related non-Hodgkin's lymphoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Etoposide; Female; Flow Cyt | 1993 |
Prednisolone, cytosine arabinoside, lomustine (CCNU), etoposide and thioguanine (PACET) combination chemotherapy for relapsed or refractory non-Hodgkin lymphoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Female; Humans; | 1993 |
Lomustine, etoposide, methotrexate and prednisone (LEMP) therapy for relapsed and refractory non-Hodgkin's lymphoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Etoposide; Female; Humans; Lomustine; L | 1993 |
Pharmacokinetics of high-dose oral CCNU in bone marrow transplant patients.
Topics: Administration, Oral; Adult; Antineoplastic Agents; Biotransformation; Bone Marrow Transplantation; | 1996 |
[Evaluation of the CCNU-COP regimen for primary refractory and recurrent non-Hodgkin's lymphoma].
Topics: Adult; Aged; Anemia; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protoco | 1999 |
Primary central nervous system lymphoma: a role for adjuvant chemotherapy.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neop | 1992 |
Feasibility of autologous bone marrow transplantation for early consolidation of follicular non-Hodgkin's lymphoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cyclophosphamide | 1991 |
Adjuvant chemotherapy for primary lymphoma of the central nervous system.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Dise | 1990 |
Phase II study of lomustine, cytarabine, mitoxantrone, and prednisone (CAMP) combination chemotherapy for doxorubicin-resistant intermediate- and high-grade malignant non-Hodgkin's lymphoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Doxorubicin; | 1990 |
[Vindesine, CCNU, high-dosage ara-C, and prednisolone (VINAP regimen) in the treatment of relapsing or refractory non-Hodgkin's lymphomas].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Evaluation; Drug | 1989 |
[Indirect endolymphatic chemotherapy of patients with lymphoma].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Hodgkin Disease; Humans; Injection | 1989 |
Failure of combination chemotherapy of advanced follicular (low-grade) non-Hodgkin's lymphoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Drug Adm | 1987 |