lomustine has been researched along with Leukemia L 1210 in 37 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "The methylnitrosoureas 3a and 3b were not significantly cytotoxic to H." | 1.27 | Nitrosoureido nucleosides as potential inhibitors of nucleotide biosynthesis. ( Adamson, DJ; Brockman, RW; Elliott, RD; Montgomery, JA; Riordan, JM; Shaddix, SC; Thomas, HJ, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 35 (94.59) | 18.7374 |
| 1990's | 1 (2.70) | 18.2507 |
| 2000's | 1 (2.70) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Johnston, TP | 3 |
| McCaleb, GS | 3 |
| Clayton, SD | 1 |
| Frye, JL | 1 |
| Krauth, CA | 1 |
| Montgomery, JA | 6 |
| Mayo, JG | 1 |
| Laster, WR | 1 |
| Elliott, RD | 1 |
| Thomas, HJ | 1 |
| Shaddix, SC | 1 |
| Adamson, DJ | 1 |
| Brockman, RW | 1 |
| Riordan, JM | 1 |
| Weinkam, RJ | 1 |
| Dolan, ME | 1 |
| Rodriguez, M | 1 |
| Imbach, JL | 2 |
| Martinez, J | 2 |
| Tsujihara, K | 1 |
| Ozeki, M | 1 |
| Morikawa, T | 1 |
| Kawamori, M | 1 |
| Akaike, Y | 1 |
| Arai, Y | 1 |
| Hansch, C | 1 |
| Leo, A | 1 |
| Schmidt, C | 1 |
| Jow, PY | 1 |
| Foster, AB | 1 |
| Jarman, M | 1 |
| Coe, PL | 1 |
| Sleigh, J | 1 |
| Tatlow, JC | 1 |
| Perjési, P | 1 |
| Das, U | 1 |
| De Clercq, E | 1 |
| Balzarini, J | 1 |
| Kawase, M | 1 |
| Sakagami, H | 1 |
| Stables, JP | 1 |
| Lorand, T | 1 |
| Rozmer, Z | 1 |
| Dimmock, JR | 1 |
| Ahlgren, JD | 1 |
| Green, DC | 1 |
| Tew, KD | 2 |
| Schein, PS | 5 |
| Lazarus, P | 1 |
| Germina, JS | 1 |
| Dufour, M | 1 |
| Palmer, G | 1 |
| Wallace, D | 1 |
| Panasci, LC | 2 |
| Kann, HE | 2 |
| Schott, MA | 1 |
| Petkas, A | 1 |
| Macdonald, JS | 1 |
| Hoth, D | 1 |
| Oiry, J | 1 |
| Winternitz, F | 1 |
| Valeriote, F | 1 |
| Medoff, G | 1 |
| Tolen, S | 1 |
| Dieckman, J | 1 |
| Oguro, M | 1 |
| Yanagawa, T | 1 |
| Takenaga, K | 1 |
| Mulcahy, RT | 1 |
| Siemann, DW | 1 |
| Bello, JL | 1 |
| Kariev, NI | 1 |
| Mainardi, JV | 1 |
| Betancourt, M | 1 |
| Lage, A | 1 |
| Barroso, MC | 1 |
| Alfonso, L | 1 |
| Gibson, NW | 1 |
| Hickman, JA | 1 |
| Woolley, PV | 1 |
| Dion, RL | 1 |
| Kohn, KW | 3 |
| Bono, VH | 1 |
| Bhuyan, BK | 1 |
| Fraser, TJ | 1 |
| Day, KJ | 1 |
| Green, D | 1 |
| Nagourney, R | 1 |
| Fox, P | 1 |
| Heal, JM | 1 |
| Fox, PA | 1 |
| Doukas, D | 1 |
| Ewig, RA | 2 |
| Goldin, A | 1 |
| Schabel, FM | 1 |
| Hilton, J | 1 |
| Bowie, DL | 1 |
| Gutin, PH | 1 |
| Zito, DM | 1 |
| Walker, MD | 1 |
| Colvin, M | 1 |
| Brundrett, RB | 1 |
| Cowens, W | 1 |
| Jardine, I | 1 |
| Ludlum, DB | 1 |
| Shimizu, F | 1 |
| Arakawa, M | 1 |
| Osswald, H | 1 |
| Frank, N | 1 |
| Dean, SW | 1 |
| Clark, AE | 1 |
| Beljanski, M | 1 |
| Beljanski, MS | 1 |
| Pouillart, R | 1 |
| Huong, TH | 1 |
| Brugerie, E | 1 |
| Lheritier, J | 1 |
1 review available for lomustine and Leukemia L 1210
| Article | Year |
|---|---|
Nitrosoureas: a review of experimental antitumor activity.
Topics: Animals; Carmustine; Colonic Neoplasms; Drug Evaluation, Preclinical; Drug Resistance; Drug Therapy, | 1976 |
36 other studies available for lomustine and Leukemia L 1210
| Article | Year |
|---|---|
Synthesis of analogues of N-(2-chloroethyl)-N'-(trans-4-methylcyclohexyl)-N-nitrosourea for evaluation as anticancer agents.
Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Isomerism; Leukemia L1210; Mice; Mice | 1977 |
Inhibition of solid tumors by nitrosoureas. 1. Lewis lung carcinoma.
Topics: Animals; Carcinoma; Leukemia L1210; Lung Neoplasms; Mice; Mice, Inbred Strains; Neoplasms, Experimen | 1977 |
Nitrosoureido nucleosides as potential inhibitors of nucleotide biosynthesis.
Topics: Animals; Carmustine; Cell Division; DNA Replication; Drug Stability; Indicators and Reagents; Leukem | 1988 |
An analysis of 1-(2-chloroethyl)-1-nitrosourea activity at the cellular level.
Topics: Animals; Antineoplastic Agents; Carmustine; Cell Survival; Drug Evaluation, Preclinical; Ethylnitros | 1983 |
Synthesis and antitumor evaluation of some nitrosourea and nitrogen mustard amino acid derivatives.
Topics: Animals; Antineoplastic Agents; Leukemia L1210; Mice; Nitrogen Mustard Compounds; Nitrosourea Compou | 1984 |
A new class of nitrosoureas. 4. Synthesis and antitumor activity of disaccharide derivatives of 3,3-disubstituted 1-(2-chloroethyl)-1-nitrosoureas.
Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Chemical Phenomena; Chemistry; Leukemia L1 | 1982 |
Antitumor structure-activity relations. Nitrosoureas vs. L-1210 leukemia.
Topics: Animals; Antineoplastic Agents; Leukemia L1210; Mice; Models, Theoretical; Nitrosourea Compounds; So | 1980 |
Fluorinated analogues of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea: an attempt to control metabolism.
Topics: Animals; Antineoplastic Agents; Female; Leukemia L1210; Lomustine; Lymphoma; Mice; Neoplasms, Experi | 1980 |
Design, synthesis and antiproliferative activity of some 3-benzylidene-2,3-dihydro-1-benzopyran-4-ones which display selective toxicity for malignant cells.
Topics: Animals; Antineoplastic Agents; Benzopyrans; Cell Survival; Drug Design; Drug Screening Assays, Anti | 2008 |
Repair of DNA alkylation induced in L1210 leukemia and murine bone marrow by three chloroethylnitrosoureas.
Topics: Alkylation; Animals; Bone Marrow; DNA; DNA Repair; DNA, Neoplasm; In Vitro Techniques; Leukemia L121 | 1982 |
Comparison of the transport of chlorozotocin and CCNU in L1210 leukemia and murine bone marrow cells in vitro.
Topics: Animals; Biological Transport; Bone Marrow; In Vitro Techniques; Leukemia L1210; Lomustine; Male; Mi | 1983 |
Effects of structure and chemical activity on the ability of nitrosoureas to inhibit DNA repair.
Topics: Animals; Carmustine; Cells, Cultured; DNA Repair; Leukemia L1210; Lomustine; Mice; Nitrosourea Compo | 1980 |
Preclinical and clinical studies on chlorozotocin, a new nitrosourea with decreased bone marrow toxicity.
Topics: Animals; Bone Marrow; Carmustine; Drug Evaluation; Drug Evaluation, Preclinical; Female; Humans; Leu | 1980 |
Activated N-nitrosocarbamates for regioselective synthesis of N-nitrosoureas.
Topics: Animals; Antineoplastic Agents; Leukemia L1210; Lomustine; Mice; Nitrosourea Compounds; Streptozocin | 1982 |
Amphotericin B potentiation of the cytotoxicity of anticancer agents against both normal hematopoietic and leukemia cells in mice.
Topics: Amphotericin B; Animals; Antineoplastic Agents; Cell Survival; Doxorubicin; Drug Synergism; Hematopo | 1984 |
[Antitumor activity of a new nitrosourea, MCNU, on a cellular morphological basis evaluated by a new in vitro antitumor sensitivity assay].
Topics: Animals; Antineoplastic Agents; Carmustine; Cell Survival; Dose-Response Relationship, Drug; Drug Re | 1984 |
In vivo chemosensitization by misonidazole in sensitive and resistant tumor lines.
Topics: Animals; Carmustine; Cell Line; Drug Resistance; Drug Synergism; Humans; Leukemia L1210; Lomustine; | 1983 |
Experimental approach for the search of effective drug combination in cancer chemotherapy.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cyclophosphamide; Drug Therapy, Combination; Leukemi | 1982 |
The role of isocyanates in the toxicity of antitumour haloalkylnitrosoureas.
Topics: Animals; Antineoplastic Agents; Carmustine; Cyanates; Female; Leukemia L1210; Lomustine; Lymphoma; M | 1982 |
Binding of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea to L1210 cell nuclear proteins.
Topics: Animals; Cell Nucleus; Cell Survival; Cells, Cultured; DNA, Neoplasm; Histones; Hydrogen-Ion Concent | 1976 |
Cell proliferation kinetics and drug sensitivity of exponential and stationary populations of cultured L1210 cells.
Topics: Amino Acids; Animals; Antineoplastic Agents; Carmustine; Cell Division; Cell Survival; Cells, Cultur | 1977 |
A structure-activity analysis of chemical and biological parameters of chloroethylnitrosoureas in mice.
Topics: Alkylation; Animals; Bone Marrow; Carmustine; Ethyl Chloride; Ethylnitrosourea; Half-Life; Leukemia | 1977 |
Biological and biochemical properties of the 2-hydroxyl metabolites of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea.
Topics: Alkylation; Animals; Bone Marrow; Dose-Response Relationship, Drug; Hematopoiesis; Humans; In Vitro | 1978 |
Comparison of biochemical and biological effects of four nitrosoureas with differing carbamoylating activities.
Topics: Animals; Carmustine; Cell Survival; Cells, Cultured; Chemical Phenomena; Chemistry; DNA, Neoplasm; E | 1978 |
DNA-protein cross-linking and DNA interstrand cross-linking by haloethylnitrosoureas in L1210 cells.
Topics: Animals; Carmustine; Cells, Cultured; Chemical Phenomena; Chemistry; DNA, Neoplasm; Endopeptidases; | 1978 |
DNA damage and repair in mouse leukemia L1210 cells treated with nitrogen mustard, 1,3-bis(2-chloroethyl)-1-nitrosourea, and other nitrosoureas.
Topics: Animals; Carmustine; Cell Survival; Cells, Cultured; Chemical Phenomena; Chemistry; DNA Repair; DNA, | 1977 |
Rationale of chemotherapeutic adjuvant treatment.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Carmustine; Cyclophosphamide; Drug Admi | 1978 |
DNA damage and repair in L1210 cells exposed to 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea.
Topics: Animals; Cells, Cultured; Centrifugation, Density Gradient; DNA Repair; DNA, Neoplasm; DNA, Single-S | 1977 |
A chemical basis for the antitumor activity of chloroethylnitrosoureas.
Topics: Animals; Antineoplastic Agents; Buffers; Carmustine; Chemical Phenomena; Chemistry; Ethylnitrosourea | 1976 |
Chemistry and structure-activity studies of the nitrosoureas.
Topics: Adenocarcinoma; Animals; Leukemia L1210; Lomustine; Lung Neoplasms; Mice; Neoplasms, Experimental; N | 1976 |
Effect of 3-[4-amino-2-methyl-5-pyrimidinyl)ethyl[-1(2-chloroethyl)-1-nitrosourea hydrochloride on lymphoid leukemia L-1210.
Topics: Administration, Oral; Animals; Carbazilquinone; Cyclophosphamide; Daunorubicin; Dose-Response Relati | 1975 |
Synthesis and biologic evaluation of major metabolites of N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosourea.
Topics: Animals; Leukemia L1210; Lomustine; Mice; Nitrosourea Compounds; Stereoisomerism; Structure-Activity | 1975 |
Sacrosine- and prolinedithiocarbamate pretreatment increases the therapeutic efficacy of doxorubicin, methotrexate, teniposide, mitoxantrone or cyclohexylchloroethylnitrosourea in leukemia L1210.
Topics: Animals; Antineoplastic Agents; Cysteine; Doxorubicin; Drug Synergism; Female; Leukemia L1210; Lomus | 1990 |
DNA repeat length in chromatin from murine bone marrow and L1210 leukaemia cells.
Topics: Animals; Bone Marrow; Cells, Cultured; Chromatin; DNA; DNA, Neoplasm; Electrophoresis, Agar Gel; Ele | 1985 |
Three alkaloids as selective destroyers of cancer cells in mice. Synergy with classic anticancer drugs.
Topics: Alkaloids; Animals; Antineoplastic Combined Chemotherapy Protocols; Daunorubicin; Drug Synergism; Fl | 1986 |
Sequential administration of two oncostatic drugs: study of modalities for pharmacodynamic potentiation.
Topics: Animals; Antineoplastic Agents; Carmustine; Cyclophosphamide; Cytarabine; Dactinomycin; Drug Synergi | 1974 |