Page last updated: 2024-10-30

lomustine and Leucocythaemia

lomustine has been researched along with Leucocythaemia in 15 studies

Research Excerpts

ExcerptRelevanceReference
"In addition to mechlorethamine, lomustine and teniposide combinations were also linked to an elevated risk of developing leukemia."3.69Leukemia risk following Hodgkin's disease: relation to cumulative dose of alkylating agents, treatment with teniposide combinations, number of episodes of chemotherapy, and bone marrow damage. ( Chorus, AM; Hagenbeek, A; Noyon, R; Pinedo, HM; Somers, R; van den Belt-Dusebout, AW; van Kerkhoff, EH; van Leeuwen, FE, 1994)
"2676 Patients entered into Hodgkin's disease studies between February 1970 and November 1986."2.67Leukaemia complicating treatment for Hodgkin's disease: the experience of the British National Lymphoma Investigation. ( Devereux, S; Linch, DC; Selassie, TG; Vaughan Hudson, B; Vaughan Hudson, G, 1990)
"Etoposide has also been tested in a wide range of combination regimens, but for many of these combinations, relatively few patients are included, and some combinations have only been tested in patients who have undergone autologous transplants."2.48High-dose etoposide in allogeneic stem cell transplantation. ( Ahmed, AB; Bruserud, O; Hatfield, KJ; Kittang, AO; Reikvam, H; Sjo, M; Tvedt, TH, 2012)
" Since no epidemiological data in man are available, extrapolation of animal data to man are important as well as dose-response studies in risk evaluations."2.37Carcinogenic N-nitroso compounds and their environmental significance. ( Preussmann, R, 1984)
"Risk of leukemia was 0."1.30The risk of acute leukemia in patients treated for Hodgkin's disease is significantly higher aft [see bined modality programs than after chemotherapy alone and is correlated with the extent of radiotherapy and type and duration of chemotherapy: a case-con ( Anselmo, AP; Baroni, CD; Bernasconi, C; Brusamolino, E; Klersy, C; Lazzarino, M; Lunghi, F; Mandelli, F; Maurizi-Enrici, R; Orlandi, E; Pagnucco, G; Santoro, M, 1998)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-199010 (66.67)18.7374
1990's4 (26.67)18.2507
2000's0 (0.00)29.6817
2010's1 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bruserud, O1
Reikvam, H1
Kittang, AO1
Ahmed, AB1
Tvedt, TH1
Sjo, M1
Hatfield, KJ1
Robustelli della Cuna, G1
Paoletti, P1
Bernardo, G1
Knerich, R1
Butti, G1
Cuzzoni, Q1
Preussmann, R1
Grünewald, K1
Abbrederis, K1
Gorin, NC1
David, R1
Stachowiak, J1
Salmon, C1
Petit, JC1
Parlier, Y1
Najman, A1
Duhamel, G1
van Leeuwen, FE1
Chorus, AM1
van den Belt-Dusebout, AW1
Hagenbeek, A1
Noyon, R1
van Kerkhoff, EH1
Pinedo, HM1
Somers, R1
Brusamolino, E1
Anselmo, AP1
Klersy, C1
Santoro, M1
Orlandi, E1
Pagnucco, G1
Lunghi, F1
Maurizi-Enrici, R1
Baroni, CD1
Lazzarino, M1
Mandelli, F1
Bernasconi, C2
Massimo, L1
Comelli, A1
Garrett, MJ1
Das, S1
Smith, JD1
Freedman, LS1
Longo, DL1
Duffey, PL1
DeVita, VT1
Wiernik, PH2
Hubbard, SM1
Phares, JC1
Bastian, AW1
Jaffe, ES1
Young, RC1
Devereux, S1
Selassie, TG1
Vaughan Hudson, G1
Vaughan Hudson, B1
Linch, DC1
Dutcher, JP1
Straus, DJ1
Pedersen-Bjergaard, J1
Osterlind, K1
Hansen, M1
Philip, P1
Pedersen, AG1
Hansen, HH1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Intensive Conditioning Regimen With Thiotepa Combined With Busulfan, Fludarabine and Cytarabine for Allogeneic Hematopoietic Stem Cell Transplantation in the Treatment of Myeloid Malignancies With Extramedullary Involvement[NCT06111612]50 participants (Anticipated)Observational2024-01-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for lomustine and Leucocythaemia

ArticleYear
High-dose etoposide in allogeneic stem cell transplantation.
    Cancer chemotherapy and pharmacology, 2012, Volume: 70, Issue:6

    Topics: Adenine Nucleotides; Anthracyclines; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chem

2012
Carcinogenic N-nitroso compounds and their environmental significance.
    Die Naturwissenschaften, 1984, Volume: 71, Issue:1

    Topics: Alkylation; Animals; Brain Neoplasms; Carcinogens; Carcinogens, Environmental; Carmustine; Dimethyln

1984
Treatment of advanced Hodgkin's disease.
    Hematology/oncology clinics of North America, 1989, Volume: 3, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Clinical Trials as Top

1989
Etoposide: fifteen years experience.
    Bone marrow transplantation, 1989, Volume: 4 Suppl 1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Evaluation; Etoposide; Hodgkin Dise

1989

Trials

3 trials available for lomustine and Leucocythaemia

ArticleYear
Treatment of advanced-stage Hodgkin's disease: alternating noncrossresistant MOPP/CABS is not superior to MOPP.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1991, Volume: 9, Issue:8

    Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Dose-Re

1991
Leukaemia complicating treatment for Hodgkin's disease: the experience of the British National Lymphoma Investigation.
    BMJ (Clinical research ed.), 1990, Nov-10, Volume: 301, Issue:6760

    Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Case-Control Studi

1990
Treatment of advanced Hodgkin's disease.
    Hematology/oncology clinics of North America, 1989, Volume: 3, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Clinical Trials as Top

1989

Other Studies

9 other studies available for lomustine and Leucocythaemia

ArticleYear
Clinical toxicity of combined modality treatment with nitrosourea derivatives for central nervous system tumors.
    Neurosurgery, 1982, Volume: 11, Issue:3

    Topics: Bone Marrow Diseases; Brain Neoplasms; Carmustine; Gastrointestinal Diseases; Glioblastoma; Glioma;

1982
[Long-term survival and fatal late relapse in acute leukaemia in adults].
    Wiener klinische Wochenschrift, 1983, May-13, Volume: 95, Issue:10

    Topics: Acute Disease; Adolescent; Adult; Cyclophosphamide; Female; Humans; Leukemia; Lomustine; Male; Metho

1983
High dose chemotherapy and autologous bone marrow transplantation in acute leukemias, malignant lymphomas and solid tumors. A study of 23 patients.
    European journal of cancer, 1981, Volume: 17, Issue:5

    Topics: Adolescent; Adult; Bone Marrow Transplantation; Cyclophosphamide; Cytarabine; Drug Therapy, Combinat

1981
Leukemia risk following Hodgkin's disease: relation to cumulative dose of alkylating agents, treatment with teniposide combinations, number of episodes of chemotherapy, and bone marrow damage.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1994, Volume: 12, Issue:5

    Topics: Adult; Aged; Alkylating Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Case-Co

1994
The risk of acute leukemia in patients treated for Hodgkin's disease is significantly higher aft [see bined modality programs than after chemotherapy alone and is correlated with the extent of radiotherapy and type and duration of chemotherapy: a case-con
    Haematologica, 1998, Volume: 83, Issue:9

    Topics: Abdomen; Actuarial Analysis; Acute Disease; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over;

1998
[New drugs for the therapy of acute leukemia].
    Minerva medica, 1975, Jul-28, Volume: 66, Issue:52

    Topics: Acute Disease; Antineoplastic Agents; Azacitidine; Cytarabine; Daunorubicin; Doxorubicin; Drug Thera

1975
Long term experience with combination chemotherapy in advanced Hodgkin's disease.
    Clinical oncology, 1977, Volume: 3, Issue:2

    Topics: Adult; Antineoplastic Agents; Bleomycin; Drug Therapy, Combination; Female; Hodgkin Disease; Humans;

1977
Acute leukemia in a patient cured of diffuse histiocytic lymphoma.
    Journal of cancer research and clinical oncology, 1986, Volume: 112, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chromosome Deletion; Chromosomes, Human,

1986
Acute nonlymphocytic leukemia, preleukemia, and solid tumors following intensive chemotherapy of small cell carcinoma of the lung.
    Blood, 1985, Volume: 66, Issue:6

    Topics: Acute Disease; Carcinoma, Small Cell; Chromosome Aberrations; Chromosome Disorders; Cyclophosphamide

1985