Page last updated: 2024-10-30

lomustine and Invasiveness, Neoplasm

lomustine has been researched along with Invasiveness, Neoplasm in 11 studies

Research Excerpts

ExcerptRelevanceReference
" Adult patients (≥18 years of age) with a first recurrence of a glioblastoma after temozolomide chemoradiotherapy were randomly allocated by a web-based program to treatment with oral lomustine 110 mg/m(2) once every 6 weeks, intravenous bevacizumab 10 mg/kg once every 2 weeks, or combination treatment with lomustine 110 mg/m(2) every 6 weeks and bevacizumab 10 mg/kg every 2 weeks."9.19Single-agent bevacizumab or lomustine versus a combination of bevacizumab plus lomustine in patients with recurrent glioblastoma (BELOB trial): a randomised controlled phase 2 trial. ( Beerepoot, LV; Boerman, D; Brandsma, D; Bromberg, JE; Buter, J; de Vos, FY; Dinjens, WN; Dubbink, HJ; Enting, RH; Hanse, MC; Honkoop, AH; Jansen, RL; Oosterkamp, HM; Taal, W; Taphoorn, MJ; van den Bent, MJ; van den Berkmortel, FW; van der Holt, B; van Heuvel, I; Vernhout, RM; Walenkamp, AM, 2014)
" Adult patients (≥18 years of age) with a first recurrence of a glioblastoma after temozolomide chemoradiotherapy were randomly allocated by a web-based program to treatment with oral lomustine 110 mg/m(2) once every 6 weeks, intravenous bevacizumab 10 mg/kg once every 2 weeks, or combination treatment with lomustine 110 mg/m(2) every 6 weeks and bevacizumab 10 mg/kg every 2 weeks."5.19Single-agent bevacizumab or lomustine versus a combination of bevacizumab plus lomustine in patients with recurrent glioblastoma (BELOB trial): a randomised controlled phase 2 trial. ( Beerepoot, LV; Boerman, D; Brandsma, D; Bromberg, JE; Buter, J; de Vos, FY; Dinjens, WN; Dubbink, HJ; Enting, RH; Hanse, MC; Honkoop, AH; Jansen, RL; Oosterkamp, HM; Taal, W; Taphoorn, MJ; van den Bent, MJ; van den Berkmortel, FW; van der Holt, B; van Heuvel, I; Vernhout, RM; Walenkamp, AM, 2014)
"Nine patients with stage III and stage IV thymoma were treated with cisplatin, vincristine, lomustine, cyclophosphamide and prednisolone."3.69Combination chemotherapy with a five-drug regimen for invasive thymoma. ( Bjerrum, OW; Daugaard, G; Kiss, K, 1996)
"Forty patients with invasive bladder tumors were consecutively treated and followed between June 1986 and February 1993."2.67Combined immunochemotherapy (CEP, M-VEP + BCG) in the treatment of invasive bladder tumors. ( Chuchkova, M; Damianov, C; Koleva, P; Terziev, T, 1994)
"Malignant gliomas are the most common primary intrinsic brain tumors and are highly lethal."1.35Nitrosoureas inhibit the stathmin-mediated migration and invasion of malignant glioma cells. ( Choi, Y; Liang, XJ; Park, JK; Sackett, DL, 2008)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19901 (9.09)18.7374
1990's4 (36.36)18.2507
2000's3 (27.27)29.6817
2010's3 (27.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shih, JL1
Brenn, S1
Schrope, DP1
Taal, W1
Oosterkamp, HM1
Walenkamp, AM1
Dubbink, HJ1
Beerepoot, LV1
Hanse, MC1
Buter, J1
Honkoop, AH1
Boerman, D1
de Vos, FY1
Dinjens, WN1
Enting, RH1
Taphoorn, MJ1
van den Berkmortel, FW1
Jansen, RL1
Brandsma, D1
Bromberg, JE1
van Heuvel, I1
Vernhout, RM1
van der Holt, B1
van den Bent, MJ1
Liang, XJ1
Choi, Y1
Sackett, DL1
Park, JK1
Agha, CA1
Ibrahim, S1
Hassan, A1
Elias, DA1
Fathallah-Shaykh, HM1
Chamberlain, MC2
Damianov, C1
Terziev, T1
Koleva, P1
Chuchkova, M1
Packer, RJ1
Sutton, LN1
Elterman, R1
Lange, B1
Goldwein, J1
Nicholson, HS1
Mulne, L1
Boyett, J1
D'Angio, G1
Wechsler-Jentzsch, K1
Bjerrum, OW1
Kiss, K1
Daugaard, G1
Greenberg, HS1
Glantz, MJ1
Wang, S1
Barth, RJ1
Venzon, DJ1
Baker, AR1
Albers, GW1
Hoyt, WF1
Forno, LS1
Shratter, LA1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase II Study of Bevacizumab and Nimustine in Patients With Recurrent High Grade Glioma[NCT02698280]Phase 223 participants (Actual)Interventional2015-07-31Completed
Temozolomide Plus Bevacizumab Chemotherapy in Supratentorial Glioblastoma in 70 Years and Older Patients With an Impaired Functional Status (KPS<70)[NCT02898012]Phase 270 participants (Actual)Interventional2010-10-31Completed
An International, Randomized, Open-label Phase I/II Study of Vismodegib in Combination With Temozolomide Versus Temozolomide Alone in Adult Patients With Recurrent or Refractory Medulloblastomas Presenting an Activation of the Sonic Hedgehog (SHH) Pathway[NCT01601184]Phase 1/Phase 224 participants (Actual)Interventional2012-06-30Terminated (stopped due to The number of successes is not reached at the end of first stage of the phase II. The study is stopped.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for lomustine and Invasiveness, Neoplasm

ArticleYear
Adult medulloblastoma: multiagent chemotherapy.
    Neuro-oncology, 2001, Volume: 3, Issue:1

    Topics: Abdominal Pain; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cerebrospinal Flu

2001

Trials

3 trials available for lomustine and Invasiveness, Neoplasm

ArticleYear
Single-agent bevacizumab or lomustine versus a combination of bevacizumab plus lomustine in patients with recurrent glioblastoma (BELOB trial): a randomised controlled phase 2 trial.
    The Lancet. Oncology, 2014, Volume: 15, Issue:9

    Topics: Administration, Oral; Adolescent; Adult; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neopl

2014
Single-agent bevacizumab or lomustine versus a combination of bevacizumab plus lomustine in patients with recurrent glioblastoma (BELOB trial): a randomised controlled phase 2 trial.
    The Lancet. Oncology, 2014, Volume: 15, Issue:9

    Topics: Administration, Oral; Adolescent; Adult; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neopl

2014
Single-agent bevacizumab or lomustine versus a combination of bevacizumab plus lomustine in patients with recurrent glioblastoma (BELOB trial): a randomised controlled phase 2 trial.
    The Lancet. Oncology, 2014, Volume: 15, Issue:9

    Topics: Administration, Oral; Adolescent; Adult; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neopl

2014
Single-agent bevacizumab or lomustine versus a combination of bevacizumab plus lomustine in patients with recurrent glioblastoma (BELOB trial): a randomised controlled phase 2 trial.
    The Lancet. Oncology, 2014, Volume: 15, Issue:9

    Topics: Administration, Oral; Adolescent; Adult; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neopl

2014
Combined immunochemotherapy (CEP, M-VEP + BCG) in the treatment of invasive bladder tumors.
    Anti-cancer drugs, 1994, Volume: 5, Issue:3

    Topics: Administration, Intravesical; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; BCG Vacci

1994
Outcome for children with medulloblastoma treated with radiation and cisplatin, CCNU, and vincristine chemotherapy.
    Journal of neurosurgery, 1994, Volume: 81, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Neoplasms; Chemotherap

1994

Other Studies

7 other studies available for lomustine and Invasiveness, Neoplasm

ArticleYear
Cardiac involvement secondary to mediastinal lymphoma in a cat: regression with chemotherapy.
    Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology, 2014, Volume: 16, Issue:2

    Topics: Animals; Anticonvulsants; Antineoplastic Agents; Asparaginase; Cat Diseases; Cats; Drug Therapy, Com

2014
Nitrosoureas inhibit the stathmin-mediated migration and invasion of malignant glioma cells.
    Cancer research, 2008, Jul-01, Volume: 68, Issue:13

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Movement; Glioma; Lomustine; Mice;

2008
Bevacizumab is active as a single agent against recurrent malignant gliomas.
    Anticancer research, 2010, Volume: 30, Issue:2

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chem

2010
Gliomatosis cerebri: better definition, better treatment.
    Neurology, 2004, Jul-27, Volume: 63, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Astrocyt

2004
Combination chemotherapy with a five-drug regimen for invasive thymoma.
    Acta oncologica (Stockholm, Sweden), 1996, Volume: 35, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormon

1996
The prognosis of melanoma patients with metastases to two or more lymph node areas.
    Annals of surgery, 1991, Volume: 214, Issue:2

    Topics: Adolescent; Adult; BCG Vaccine; Combined Modality Therapy; Dacarbazine; Female; Humans; Immunotherap

1991
Treatment response in malignant optic glioma of adulthood.
    Neurology, 1988, Volume: 38, Issue:7

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bromodeoxyuridine; Cranial Nerve Neoplasms; F

1988