Page last updated: 2024-10-30

lomustine and Histiocytic Sarcoma

lomustine has been researched along with Histiocytic Sarcoma in 12 studies

Histiocytic Sarcoma: Malignant neoplasms composed of MACROPHAGES or DENDRITIC CELLS. Most histiocytic sarcomas present as localized tumor masses without a leukemic phase. Though the biological behavior of these neoplasms resemble lymphomas, their cell lineage is histiocytic not lymphoid.

Research Excerpts

ExcerptRelevanceReference
"The aims of this study were to report treatment outcomes for dogs with histiocytic sarcoma (HS) treated with both lomustine and epirubicin, and to report response rates to epirubicin as a rescue therapy in dogs previously treated with lomustine."7.88Epirubicin in the treatment of canine histiocytic sarcoma: sequential, alternating and rescue chemotherapy. ( Blackwood, L; Finotello, R; Mason, SL, 2018)
"To describe a chemotherapy protocol combining lomustine and doxorubicin in canine histiocytic sarcoma, including outcomes and toxicity."7.81Evaluation of a combination chemotherapy protocol including lomustine and doxorubicin in canine histiocytic sarcoma. ( Borgatti, A; Cannon, C; Henson, M; Husbands, B, 2015)
"Lomustine is a well-accepted, first-line chemotherapy for dogs with HS, but its specific utility in dogs with HPHS has not been previously reported."5.48Lomustine chemotherapy for the treatment of presumptive haemophagocytic histiocytic sarcoma in Flat-coated Retrievers. ( Elliott, J, 2018)
"The aims of this study were to report treatment outcomes for dogs with histiocytic sarcoma (HS) treated with both lomustine and epirubicin, and to report response rates to epirubicin as a rescue therapy in dogs previously treated with lomustine."3.88Epirubicin in the treatment of canine histiocytic sarcoma: sequential, alternating and rescue chemotherapy. ( Blackwood, L; Finotello, R; Mason, SL, 2018)
"To describe a chemotherapy protocol combining lomustine and doxorubicin in canine histiocytic sarcoma, including outcomes and toxicity."3.81Evaluation of a combination chemotherapy protocol including lomustine and doxorubicin in canine histiocytic sarcoma. ( Borgatti, A; Cannon, C; Henson, M; Husbands, B, 2015)
"Primary pulmonary histiocytic sarcoma (PHS) is a rare form of dendritic cell or macrophage neoplasia originating within the pulmonary parenchyma."1.72Outcome in dogs with curative-intent treatment of localized primary pulmonary histiocytic sarcoma. ( Al-Nadaf, S; Clifford, C; Cook, MR; De Mello Souza, CH; Herrera, CL; Husbands, B; Krick, E; Leeper, H; McMillan, S; Murray, CA; Pellin, M; Richardson, D; Skorupski, KA; Willcox, JL, 2022)
"Lomustine is a well-accepted, first-line chemotherapy for dogs with HS, but its specific utility in dogs with HPHS has not been previously reported."1.48Lomustine chemotherapy for the treatment of presumptive haemophagocytic histiocytic sarcoma in Flat-coated Retrievers. ( Elliott, J, 2018)
"Multifocal histiocytic sarcoma with a spindle-cell pattern was diagnosed based on morphologic features and intense expression of CD18."1.38Multifocal cutaneous histiocytic sarcoma in a young dog and review of histiocytic cell immunophenotyping. ( Aubry, OA; Christopherson, PW; Kennis, RA; Mastrorilli, C; Moore, PF; Newton, JC; Smith, AN; Spangler, EA; Weismann, JL, 2012)
"This is the first case of histiocytic sarcoma in a cat to be reported in Japan."1.35Disseminated histiocytic sarcoma with excessive hemophagocytosis in a cat. ( Fujino, Y; Ide, K; Nakagawa, T; Nakayama, H; Ohno, K; Setoguchi-Mukai, A; Tsujimoto, H; Uetsuka, K, 2009)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (16.67)29.6817
2010's6 (50.00)24.3611
2020's4 (33.33)2.80

Authors

AuthorsStudies
Murray, CA1
Willcox, JL1
De Mello Souza, CH1
Husbands, B2
Cook, MR1
Clifford, C1
Leeper, H1
Pellin, M1
Richardson, D1
Herrera, CL1
Krick, E1
McMillan, S1
Al-Nadaf, S1
Skorupski, KA2
Patten, S1
MacKenzie, S1
Soileau, AM1
Neto, RLALT1
Jimenez, PT1
Hamersky, J1
Smith, AA1
Purzycka, K1
Peters, LM1
Elliott, J2
Lamb, CR1
Priestnall, SL1
Hardas, A1
Johnston, CA1
Rodriguez-Piza, I1
Mason, SL1
Finotello, R1
Blackwood, L1
Jackson, AE1
Cannon, C1
Borgatti, A1
Henson, M1
Yamazaki, H1
Takagi, S1
Hosoya, K1
Okumura, M1
Rodriguez, CO1
Krick, EL1
Clifford, CA1
Ward, R1
Kent, MS1
Ide, K1
Setoguchi-Mukai, A1
Nakagawa, T1
Uetsuka, K1
Nakayama, H1
Fujino, Y1
Ohno, K1
Tsujimoto, H1
Mastrorilli, C1
Spangler, EA1
Christopherson, PW1
Aubry, OA1
Newton, JC1
Smith, AN1
Kennis, RA1
Weismann, JL1
Moore, PF1

Other Studies

12 other studies available for lomustine and Histiocytic Sarcoma

ArticleYear
Outcome in dogs with curative-intent treatment of localized primary pulmonary histiocytic sarcoma.
    Veterinary and comparative oncology, 2022, Volume: 20, Issue:2

    Topics: Animals; Dog Diseases; Dogs; Histiocytic Sarcoma; Lomustine; Lung; Lung Neoplasms; Retrospective Stu

2022
Prolonged Survival Following Treatment of Histiocytic Sarcoma of the Canine Urinary Bladder.
    Journal of the American Animal Hospital Association, 2022, May-01, Volume: 58, Issue:3

    Topics: Animals; Dog Diseases; Dogs; Doxorubicin; Histiocytic Sarcoma; Lomustine; Male; Urinary Bladder

2022
Doxorubicin and zoledronate treatment in a dog with hemophagocytic histiocytic sarcoma.
    The Canadian veterinary journal = La revue veterinaire canadienne, 2023, Volume: 64, Issue:12

    Topics: Animals; Dog Diseases; Dogs; Doxorubicin; Histiocytic Sarcoma; Hyperbilirubinemia; Hypoalbuminemia;

2023
Histiocytic sarcoma in miniature schnauzers: 30 cases.
    The Journal of small animal practice, 2020, Volume: 61, Issue:6

    Topics: Animals; Dog Diseases; Dogs; Histiocytic Sarcoma; Lomustine; Retrospective Studies

2020
Epirubicin in the treatment of canine histiocytic sarcoma: sequential, alternating and rescue chemotherapy.
    Veterinary and comparative oncology, 2018, Volume: 16, Issue:1

    Topics: Animals; Antineoplastic Agents; Dog Diseases; Dogs; Epirubicin; Female; Histiocytic Sarcoma; Lomusti

2018
Lomustine chemotherapy for the treatment of presumptive haemophagocytic histiocytic sarcoma in Flat-coated Retrievers.
    Australian veterinary journal, 2018, Volume: 96, Issue:12

    Topics: Animals; Antineoplastic Agents, Alkylating; Dog Diseases; Dogs; Histiocytic Sarcoma; Lomustine; Lymp

2018
In this issue - December 2018: Pro bono wildlife work in Australian veterinary practices · Roaming owned dogs in Northern Australia · Snake stomach recovers after gastrectomy · Metronidazole-induced neurotoxicity in 26 dogs · Lomustine ineffective for hae
    Australian veterinary journal, 2018, Volume: 96, Issue:12

    Topics: Animal Welfare; Animals; Australia; Dogs; Gastrectomy; Histiocytic Sarcoma; Lomustine; Metronidazole

2018
Evaluation of a combination chemotherapy protocol including lomustine and doxorubicin in canine histiocytic sarcoma.
    The Journal of small animal practice, 2015, Volume: 56, Issue:7

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Dog Diseases; Dogs;

2015
Influence of a survivin suppressor YM155 on the chemoresistance of canine histiocytic sarcoma cells.
    Veterinary journal (London, England : 1997), 2015, Volume: 205, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Cell Line, Tumor; Dog Diseases; Dogs; Drug Resistance, N

2015
Long-term survival in dogs with localized histiocytic sarcoma treated with CCNU as an adjuvant to local therapy.
    Veterinary and comparative oncology, 2009, Volume: 7, Issue:2

    Topics: Animals; Antineoplastic Agents; Chemotherapy, Adjuvant; Cohort Studies; Disease-Free Survival; Dog D

2009
Disseminated histiocytic sarcoma with excessive hemophagocytosis in a cat.
    The Journal of veterinary medical science, 2009, Volume: 71, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Cat Diseases; Cats; Fatal Outcome; Female; Histiocytic S

2009
Multifocal cutaneous histiocytic sarcoma in a young dog and review of histiocytic cell immunophenotyping.
    Veterinary clinical pathology, 2012, Volume: 41, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Antigens, CD; Antineoplastic Agents; Biopsy, Fine-Needle; Cephalexin

2012