Page last updated: 2024-10-30

lomustine and Cognition Disorders

lomustine has been researched along with Cognition Disorders in 3 studies

Cognition Disorders: Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment.

Research Excerpts

ExcerptRelevanceReference
"The addition of PCV (procarbazine, lomustine, and vincristine) chemotherapy to radiotherapy (RT) for patients with WHO grade 2 glioma improves progression-free survival (PFS)."5.19Effect of the addition of chemotherapy to radiotherapy on cognitive function in patients with low-grade glioma: secondary analysis of RTOG 98-02. ( Barger, GR; Brachman, DG; Brown, PD; Buckner, JC; Gilbert, MR; Hu, C; Mehta, MP; Prabhu, RS; Shaw, EG; Stelzer, KJ; Won, M, 2014)
"The purpose of this prospective phase II/III trial was to study the effect of therapy intensification when combining procarbazine, lomustine, and vincristine (PCV) chemotherapy with a standard course of radiation therapy (RT) on cognitive functioning for patients with World Health Organization grade 2 low-grade gliomas (LGGs)."5.19Patients with primary brain tumors. ( Behrend, SW, 2014)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Prabhu, RS1
Won, M1
Shaw, EG1
Hu, C1
Brachman, DG1
Buckner, JC1
Stelzer, KJ1
Barger, GR1
Brown, PD1
Gilbert, MR1
Mehta, MP1
Behrend, SW1
Câmara-Costa, H1
Resch, A1
Kieffer, V1
Lalande, C1
Poggi, G1
Kennedy, C1
Bull, K1
Calaminus, G1
Grill, J1
Doz, F1
Rutkowski, S1
Massimino, M1
Kortmann, RD1
Lannering, B1
Dellatolas, G1
Chevignard, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase II Study of Observation in Favorable Low-Grade Glioma and a Phase II Study of Radiation With or Without PCV Chemotherapy in Unfavorable Low-Grade Glioma[NCT00003375]Phase 2/Phase 3370 participants (Actual)Interventional1998-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for lomustine and Cognition Disorders

ArticleYear
Effect of the addition of chemotherapy to radiotherapy on cognitive function in patients with low-grade glioma: secondary analysis of RTOG 98-02.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014, Feb-20, Volume: 32, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy, Adjuvant;

2014
Patients with primary brain tumors.
    Oncology nursing forum, 2014, Volume: 41, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Che

2014
Neuropsychological Outcome of Children Treated for Standard Risk Medulloblastoma in the PNET4 European Randomized Controlled Trial of Hyperfractionated Versus Standard Radiation Therapy and Maintenance Chemotherapy.
    International journal of radiation oncology, biology, physics, 2015, Aug-01, Volume: 92, Issue:5

    Topics: Adolescent; Age Factors; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Cereb

2015