Page last updated: 2024-10-30

lomustine and Carcinoma

lomustine has been researched along with Carcinoma in 23 studies

Carcinoma: A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for cancer.

Research Excerpts

ExcerptRelevanceReference
"A combination chemotherapy (MACC) consisting of methotrexate, doxorubicin hydrochloride (Adriamycin), cyclophosphamide, and lomustine (CCNU) was given to 41 patients with stage III bronchogenic carcinoma, 34 of whom had disseminated disease."7.65Chemotherapy for bronchogenic carcinoma. Methotrexate, doxorubicin, cyclophosphamide, and lomustine. ( Arnold, DJ; Chahinian, PA; Cohen, JM; Holland, JF; Jaffrey, IS; Kirschner, PA; Purpora, DP; Teirstein, AS, 1977)
"In a prospective, randomized study the effect of cyclophosphamide, methotrexate and 5-fluorouracil combination chemotherapy was compared to the single agent, chloroethyl-cyclohexy-nitrosourea, in the treatment of hormonally refractive metastatic prostatic carcinoma."5.05Cyclophosphamide, methotrexate and 5-fluorouracil combination chemotherapy versus chloroethyl-cyclohexy-nitrosourea in the treatment of metastatic prostatic cancer. ( Herr, HW, 1982)
"The national Prostatic Cancer Project has evaluated single and combination chemotherapeutic agents for the treatment of patients with advanced prostatic cancer that has been unresponsive to hormonal therapy."3.75Chemotherapy of hormonally unresponsive prostatic carcinoma. ( deKernion, JB; Lindner, A, 1984)
"A combination chemotherapy (MACC) consisting of methotrexate, doxorubicin hydrochloride (Adriamycin), cyclophosphamide, and lomustine (CCNU) was given to 41 patients with stage III bronchogenic carcinoma, 34 of whom had disseminated disease."3.65Chemotherapy for bronchogenic carcinoma. Methotrexate, doxorubicin, cyclophosphamide, and lomustine. ( Arnold, DJ; Chahinian, PA; Cohen, JM; Holland, JF; Jaffrey, IS; Kirschner, PA; Purpora, DP; Teirstein, AS, 1977)
"Brain metastasis occurred in 0/14 patients in the PCI and 4/15 in the non-PCI (P less than or equal to ."2.64Prophylactic cranial irradiation in small cell carcinoma of the lung. A randomized study. ( Cooper, MR; Ferree, C; Jackson, DV; Muss, HB; Richards, F; Spurr, CL; White, DR, 1977)
"Identification of synchronous brain tumors prompted genetic testing for predisposition to malignancy."1.35De novo germline TP53 mutation presenting with synchronous malignancies of the central nervous system. ( Brat, DJ; Esiashvili, N; Janss, AJ; Schniederjan, MJ; Shehata, B, 2009)
" The exposure to O6-alkylguanines gave a greater enhancement of the toxic effects of ClEtSoSo than of CCNU."1.27Effect of O6-alkylguanine pretreatment on the sensitivity of human colon tumor cells to the cytotoxic effects of chloroethylating agents. ( Dolan, ME; Pegg, AE; Young, GS, 1986)
"Untreated meningeal carcinomatosis is a uniformly fatal type of metastatic disease presenting with many protean signs and symptoms."1.26Meningeal carcinomatosis. Case report and review of the literature. ( Bender, J; Bramlet, D; Giliberti, J, 1976)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199019 (82.61)18.7374
1990's3 (13.04)18.2507
2000's1 (4.35)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Montgomery, JA1
McCaleb, GS1
Johnston, TP1
Mayo, JG1
Laster, WR1
Schniederjan, MJ1
Shehata, B1
Brat, DJ1
Esiashvili, N1
Janss, AJ1
Soukop, M1
deKernion, JB1
Lindner, A1
Dalgleish, AG1
Shields, TW1
Higgins, GA1
Humphrey, EW1
Matthews, MJ1
Keehn, RJ1
Herr, HW1
Pierga, JY1
Kalifa, C1
Terrier-Lacombe, MJ1
Habrand, JL1
Lemerle, J1
Strojan, P1
Benedik, MD1
Kragelj, B1
Jereb, B1
Israel, L2
Depierre, A1
Osieka, R1
Houchens, DP1
Goldin, A1
Johnson, RK1
Panettiere, FJ1
Takita, H1
Marabella, PC1
Edgerton, F1
Rizzo, D1
Chahinian, PA1
Arnold, DJ1
Cohen, JM1
Purpora, DP1
Jaffrey, IS1
Teirstein, AS1
Kirschner, PA1
Holland, JF1
Jackson, DV1
Richards, F1
Cooper, MR1
Ferree, C1
Muss, HB1
White, DR1
Spurr, CL1
Bramlet, D1
Giliberti, J1
Bender, J1
Edmonson, JH1
Lagakos, SW1
Selawry, OS1
Perlia, CP1
Bennett, JM1
Muggia, FM1
Wampler, G1
Brodovsky, HS1
Horton, J1
Colsky, J1
Mansour, EG1
Creech, R1
Stolbach, L1
Greenspan, EM1
Levitt, M1
Ezdinli, EZ1
Carbone, PP1
Siemann, DW1
Sutherland, RM1
Wright, JC1
Dolan, ME2
Larkin, GL1
English, HF1
Pegg, AE2
Young, GS1
de Graeff, A1
de Groot, JA1
Schornagel, JH1
Chlebowski, RT1
Chlebowski, JS1
Herrold, J1
Richardson, B1
Ali, I1
Block, JB1
Oktay, E1

Reviews

5 reviews available for lomustine and Carcinoma

ArticleYear
Management of non-small-cell cancer.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1984, Volume: 92

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma; Carcinoma, Squ

1984
Chemotherapy of hormonally unresponsive prostatic carcinoma.
    The Urologic clinics of North America, 1984, Volume: 11, Issue:2

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Carmustine; Cispla

1984
Carcinoma of the choroid plexus: a pediatric experience.
    Medical and pediatric oncology, 1993, Volume: 21, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma; Chemotherapy, Adjuvant; Chil

1993
The current management of malignancy. IV.-Cancer of the lung.
    Alaska medicine, 1975, Volume: 17, Issue:3

    Topics: Adenocarcinoma; Adrenocorticotropic Hormone; Adult; Carcinoma; Carcinoma, Bronchogenic; Carcinoma, S

1975
Update in cancer chemotherapy, Part III: Lung cancer, Part 1.
    Journal of the National Medical Association, 1985, Volume: 77, Issue:10

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Bleomycin; Carcinoma; C

1985

Trials

7 trials available for lomustine and Carcinoma

ArticleYear
Chemotherapy of hormonally unresponsive prostatic carcinoma.
    The Urologic clinics of North America, 1984, Volume: 11, Issue:2

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Carmustine; Cispla

1984
Prolonged intermittent adjuvant chemotherapy with CCNU and hydroxyurea after resection of carcinoma of the lung.
    Cancer, 1982, Nov-01, Volume: 50, Issue:9

    Topics: Carcinoma; Clinical Trials as Topic; Humans; Hydroxyurea; Lomustine; Lung Neoplasms; Male; Neoplasm

1982
Cyclophosphamide, methotrexate and 5-fluorouracil combination chemotherapy versus chloroethyl-cyclohexy-nitrosourea in the treatment of metastatic prostatic cancer.
    The Journal of urology, 1982, Volume: 127, Issue:3

    Topics: Aged; Antineoplastic Agents; Carcinoma; Cyclophosphamide; Drug Therapy, Combination; Fluorouracil; F

1982
cis-Dichlorodiammineplatinum(II), adriamycin, cyclophosphamide, CCNU, and vincristine in non-small cell lung carcinoma: a preliminary report.
    Cancer treatment reports, 1979, Volume: 63, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Carcinoma; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topi

1979
Prophylactic cranial irradiation in small cell carcinoma of the lung. A randomized study.
    JAMA, 1977, Jun-20, Volume: 237, Issue:25

    Topics: Adult; Aged; Brain; Brain Neoplasms; Carcinoma; Cyclophosphamide; Doxorubicin; Drug Therapy, Combina

1977
Cyclophosphamide and CCNU in the treatment of inoperable small cell carcinoma and adenocarcinoma of the lung.
    Cancer treatment reports, 1976, Volume: 60, Issue:7

    Topics: Adenocarcinoma; Adult; Aged; Carcinoma; Cyclophosphamide; Drug Therapy, Combination; Female; Humans;

1976
Doxorubicin, cyclophosphamide, CCNU, and vincristine with or without cisplatinum in non-small cell lung cancer.
    American journal of clinical oncology, 1985, Volume: 8, Issue:2

    Topics: Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Carcinoma; Cisplati

1985

Other Studies

12 other studies available for lomustine and Carcinoma

ArticleYear
Inhibition of solid tumors by nitrosoureas. 1. Lewis lung carcinoma.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:2

    Topics: Animals; Carcinoma; Leukemia L1210; Lung Neoplasms; Mice; Mice, Inbred Strains; Neoplasms, Experimen

1977
De novo germline TP53 mutation presenting with synchronous malignancies of the central nervous system.
    Pediatric blood & cancer, 2009, Dec-15, Volume: 53, Issue:7

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma; Choroid Plex

2009
Hypertrophic pulmonary osteoarthropathy: response to chemotherapy without documented tumour response.
    Australian and New Zealand journal of medicine, 1983, Volume: 13, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bronchial Neoplasms; Carcinoma; Cyclophosphamide; Do

1983
Combined radiation and chemotherapy for advanced undifferentiated nasopharyngeal carcinoma in children.
    Medical and pediatric oncology, 1997, Volume: 28, Issue:5

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma; Chemotherapy, Adju

1997
[Recent personal results in advanced bronchial cancer. Palliative immuno-chemotherapy. 63 cases].
    Annales de medecine interne, 1976, Volume: 127, Issue:1

    Topics: Adenocarcinoma; Antineoplastic Agents; Bleomycin; Bronchial Neoplasms; Carcinoma; Carcinoma, Squamou

1976
Chemotherapy of human colon cancer xenografts in athymic nude mice.
    Cancer, 1977, Volume: 40, Issue:5 Suppl

    Topics: Acridines; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Aspartic Acid; Carcinoma

1977
Chemotherapy for bronchogenic carcinoma. Methotrexate, doxorubicin, cyclophosphamide, and lomustine.
    JAMA, 1977, May-30, Volume: 237, Issue:22

    Topics: Adenocarcinoma; Adult; Aged; Carcinoma; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Cyclophos

1977
Meningeal carcinomatosis. Case report and review of the literature.
    Neurology, 1976, Volume: 26, Issue:3

    Topics: Adult; Brain Neoplasms; Breast Neoplasms; Carcinoma; Female; Humans; Lomustine; Meninges; Methotrexa

1976
Potentiation of alkylating chemotherapy by dual function nitrofurans in multi-cell spheroids and solid tumors.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1992, Volume: 24, Issue:4

    Topics: Animals; Antineoplastic Agents; Aziridines; Bone Marrow; Carcinoma; Cell Survival; Dose-Response Rel

1992
Depletion of O6-alkylguanine-DNA alkyltransferase activity in mammalian tissues and human tumor xenografts in nude mice by treatment with O6-methylguanine.
    Cancer chemotherapy and pharmacology, 1989, Volume: 25, Issue:2

    Topics: Animals; Antineoplastic Agents; Carcinoma; Cell Line; Colonic Neoplasms; Dose-Response Relationship,

1989
Effect of O6-alkylguanine pretreatment on the sensitivity of human colon tumor cells to the cytotoxic effects of chloroethylating agents.
    Cancer research, 1986, Volume: 46, Issue:9

    Topics: Carcinoma; Cell Cycle; Cell Line; Cell Survival; Colonic Neoplasms; Humans; Lomustine; Mesylates; Me

1986
Chemotherapy with doxorubicin and CCNU in advanced undifferentiated carcinoma of the nasopharynx. A retrospective report on five patients.
    The Netherlands journal of medicine, 1987, Volume: 31, Issue:3-4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Doxorubicin; Female; H

1987