lomustine has been researched along with Arachnoidal Cerebellar Sarcoma, Circumscribed in 62 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Vincristine and lomustine are two important chemotherapeutic drugs used for the treatment of different types of neoplasms, including medulloblastomas." | 7.77 | Response of medulloblastoma cells to vincristine and lomustine: role of TRKC, CTNNB1 and STK15. ( Aboussekhra, A; Al-Hindi, H; Al-Kofide, A; Al-Shail, E; El-Kum, N; Khafaga, Y; Shinwari, Z, 2011) |
| "The survival of 20 children with medulloblastoma who received adjuvant chemotherapy with procarbazine, vincristine and prednisone after resection and craniospinal irradiation is compared with the preliminary results of the Children's Cancer Study Group (CCSG) and the international Society of Pediatric Oncology (SIOP) medulloblastoma studies." | 7.66 | Adjuvant chemotherapy with procarbazine, vincristine and prednisone for medulloblastomas. A preliminary report. ( Berchtold, W; Bernasconi, S; Feldges, A; Imbach, P; Lüthi, A; Plüss, HJ; Seiler, RW; Vassella, F; Wagner, HP; Wyss, M, 1981) |
| "Seven patients were treated with a combination of intraventricular methotrexate (MTX) and oral CCNU after resection and whole CNS irradiation of medulloblastomas." | 7.66 | Adjuvant chemotherapy with intraventricular methotrexate and CCNU after surgery and radiotherapy of medulloblastomas. ( Imbach, P; Seiler, RW; Vassella, F; Wagner, HP, 1978) |
| "Seventeen patients with recurrent medulloblastoma were treated with a combination of three drugs: procarbazine, CCNU, and vincristine (PCV)." | 7.66 | Chemotherapy of recurrent medulloblastoma with combined procarbazine, CCNU, and vincristine. ( Crafts, DC; Edwards, MS; Levin, VA; Pischer, TL; Wilson, CB, 1978) |
| " To improve treatment, voriconazole dosage was adapted to reach drug concentrations in cerebrospinal fluid (CSF) above the minimal fungicidal concentration and plasma specimens." | 5.34 | Successful treatment with voriconazole of Aspergillus brain abscess in a boy with medulloblastoma. ( Burhenne, J; Foell, JL; Reiss, T; Rengelshausen, J; Staege, MS; Stiefel, M; Wawer, A, 2007) |
| " All patients required dosage modification for toxicity." | 5.28 | Results of treatment of children with recurrent medulloblastoma/primitive neuroectodermal tumors with lomustine, cisplatin, and vincristine. ( Evans, AE; Lefkowitz, IB; Packer, RJ; Schut, L; Siegel, KR; Sutton, LN, 1990) |
| "Vincristine and lomustine are two important chemotherapeutic drugs used for the treatment of different types of neoplasms, including medulloblastomas." | 3.77 | Response of medulloblastoma cells to vincristine and lomustine: role of TRKC, CTNNB1 and STK15. ( Aboussekhra, A; Al-Hindi, H; Al-Kofide, A; Al-Shail, E; El-Kum, N; Khafaga, Y; Shinwari, Z, 2011) |
| "The aim of this study was to examine the range of sensitivity of a panel of short-term cultures derived from different types of malignant childhood brain tumours including medulloblastoma, ependymoma and glioblastoma multiforme to three cytotoxic drugs, lomustine (CCNU), vincristine (VCR) and procarbazine (PCB)." | 3.70 | Chemosensitivity in childhood brain tumours in vitro: evidence of differential sensitivity to lomustine (CCNU) and vincristine. ( Darling, JL; Harding, B; Harkness, W; Hayward, R; Lewandowicz, GM; Thomas, DG, 2000) |
| "The survival of 20 children with medulloblastoma who received adjuvant chemotherapy with procarbazine, vincristine and prednisone after resection and craniospinal irradiation is compared with the preliminary results of the Children's Cancer Study Group (CCSG) and the international Society of Pediatric Oncology (SIOP) medulloblastoma studies." | 3.66 | Adjuvant chemotherapy with procarbazine, vincristine and prednisone for medulloblastomas. A preliminary report. ( Berchtold, W; Bernasconi, S; Feldges, A; Imbach, P; Lüthi, A; Plüss, HJ; Seiler, RW; Vassella, F; Wagner, HP; Wyss, M, 1981) |
| "Seven patients were treated with a combination of intraventricular methotrexate (MTX) and oral CCNU after resection and whole CNS irradiation of medulloblastomas." | 3.66 | Adjuvant chemotherapy with intraventricular methotrexate and CCNU after surgery and radiotherapy of medulloblastomas. ( Imbach, P; Seiler, RW; Vassella, F; Wagner, HP, 1978) |
| "Seventeen patients with recurrent medulloblastoma were treated with a combination of three drugs: procarbazine, CCNU, and vincristine (PCV)." | 3.66 | Chemotherapy of recurrent medulloblastoma with combined procarbazine, CCNU, and vincristine. ( Crafts, DC; Edwards, MS; Levin, VA; Pischer, TL; Wilson, CB, 1978) |
| "Supratentorial PNET (sPNET) are rare CNS tumors of embryonal origin arising in children and adults." | 2.74 | Non-pineal supratentorial primitive neuro-ectodermal tumors (sPNET) in teenagers and young adults: Time to reconsider cisplatin based chemotherapy after cranio-spinal irradiation? ( Biswas, S; Burke, A; Burnet, NG; Cherian, S; Earl, HM; Hatcher, H; Horan, G; Jefferies, S; Nicholson, J; Williams, D; Williams, M, 2009) |
| "Medulloblastoma is the most common malignant brain tumor of childhood." | 2.69 | Treatment of children with medulloblastomas with reduced-dose craniospinal radiation therapy and adjuvant chemotherapy: A Children's Cancer Group Study. ( Allen, JC; Boyett, JM; Cohen, BH; Goldwein, J; Muraszko, K; Nicholson, HS; Packer, RJ; Ris, MD; Rorke, LB; Vezina, LG; Wara, WM, 1999) |
| "Significant advances in the treatment of medulloblastoma and primitive neuroectodermal tumors have been made in the past three decades." | 2.42 | Medulloblastomas and central nervous system primitive neuroectodermal tumors. ( McLean, TW, 2003) |
| "Patients with desmoplastic medulloblastoma and lateral tumour location (n=19) had a lower EFS compared to patients with centrally located desmoplastic tumours (n=10) (p=0." | 1.39 | Treatment of adult nonmetastatic medulloblastoma patients according to the paediatric HIT 2000 protocol: a prospective observational multicentre study. ( Deinlein, F; Friedrich, C; Hau, P; Kortmann, RD; Kuehl, J; Kwiecien, R; Pietsch, T; Rutkowski, S; von Bueren, AO; von Hoff, K; Warmuth-Metz, M, 2013) |
| "In seven MB/PNET cell lines investigated, MGMT promoter methylation was detected only in D425 human MB cells as assayed by the qualitative methylation-specific PCR and the more quantitative pyrosequencing assay." | 1.37 | Expression of O⁶-methylguanine-DNA methyltransferase in childhood medulloblastoma. ( Arnold, L; Faoro, D; Gerber, NU; Grotzer, MA; Haybaeck, J; Hegi, M; Hürlimann, ML; Mittelbronn, M; Rutkowski, S; Sciuscio, D; Shalaby, T; von Bueren, AO, 2011) |
| " To improve treatment, voriconazole dosage was adapted to reach drug concentrations in cerebrospinal fluid (CSF) above the minimal fungicidal concentration and plasma specimens." | 1.34 | Successful treatment with voriconazole of Aspergillus brain abscess in a boy with medulloblastoma. ( Burhenne, J; Foell, JL; Reiss, T; Rengelshausen, J; Staege, MS; Stiefel, M; Wawer, A, 2007) |
| "Primary hypothyroidism is a common sequela of craniospinal radiotherapy in the treatment of childhood medulloblastoma." | 1.31 | Thyroid dysfunction as a late effect in childhood medulloblastoma: a comparison of hyperfractionated versus conventionally fractionated craniospinal radiotherapy. ( Besenzon, L; Corrias, A; di Montezemolo, LC; Einaudi, S; Genitori, L; Madon, E; Ricardi, U; Sandri, A; Urgesi, A, 2001) |
| " All patients required dosage modification for toxicity." | 1.28 | Results of treatment of children with recurrent medulloblastoma/primitive neuroectodermal tumors with lomustine, cisplatin, and vincristine. ( Evans, AE; Lefkowitz, IB; Packer, RJ; Schut, L; Siegel, KR; Sutton, LN, 1990) |
| "Six of them had tumor metastasis with in 6 months after the initial treatment(s)." | 1.27 | [Brain tumors in infants and children--factors affecting prognosis, (Part-3). Mode of metastasis and prognosis in medulloblastoma]. ( Matsumoto, S; Oi, S; Raimondi, AJ, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (40.32) | 18.7374 |
| 1990's | 9 (14.52) | 18.2507 |
| 2000's | 18 (29.03) | 29.6817 |
| 2010's | 10 (16.13) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Belcher, SM | 1 |
| Burton, CC | 1 |
| Cookman, CJ | 1 |
| Kirby, M | 1 |
| Miranda, GL | 1 |
| Saeed, FO | 1 |
| Wray, KE | 1 |
| Beier, D | 1 |
| Proescholdt, M | 1 |
| Reinert, C | 1 |
| Pietsch, T | 2 |
| Jones, DTW | 1 |
| Pfister, SM | 1 |
| Hattingen, E | 1 |
| Seidel, C | 1 |
| Dirven, L | 1 |
| Luerding, R | 1 |
| Reijneveld, J | 1 |
| Warmuth-Metz, M | 2 |
| Bonsanto, M | 1 |
| Bremer, M | 1 |
| Combs, SE | 1 |
| Rieken, S | 1 |
| Herrlinger, U | 2 |
| Kuntze, H | 1 |
| Mayer-Steinacker, R | 1 |
| Moskopp, D | 1 |
| Schneider, T | 1 |
| Beringer, A | 1 |
| Schlegel, U | 1 |
| Stummer, W | 1 |
| Welker, H | 1 |
| Weyerbrock, A | 1 |
| Paulsen, F | 1 |
| Rutkowski, S | 4 |
| Weller, M | 1 |
| Wick, W | 1 |
| Kortmann, RD | 3 |
| Bogdahn, U | 2 |
| Hau, P | 3 |
| Bernstock, JD | 1 |
| Cohen, JL | 1 |
| Singh, S | 1 |
| Schlappi, CW | 1 |
| Fiveash, JB | 1 |
| Johnston, JM | 1 |
| Fequiere, P | 1 |
| Orr, BA | 1 |
| Li, R | 1 |
| Friedman, GK | 1 |
| Taylor, RE | 1 |
| Howman, AJ | 1 |
| Wheatley, K | 1 |
| Brogden, EE | 1 |
| Large, B | 1 |
| Gibson, MJ | 1 |
| Robson, K | 1 |
| Mitra, D | 1 |
| Saran, F | 1 |
| Michalski, A | 1 |
| Pizer, BL | 1 |
| Câmara-Costa, H | 1 |
| Resch, A | 1 |
| Kieffer, V | 1 |
| Lalande, C | 1 |
| Poggi, G | 2 |
| Kennedy, C | 1 |
| Bull, K | 1 |
| Calaminus, G | 1 |
| Grill, J | 1 |
| Doz, F | 1 |
| Massimino, M | 2 |
| Lannering, B | 1 |
| Dellatolas, G | 1 |
| Chevignard, M | 1 |
| Biswas, S | 1 |
| Burke, A | 1 |
| Cherian, S | 1 |
| Williams, D | 1 |
| Nicholson, J | 1 |
| Horan, G | 1 |
| Jefferies, S | 1 |
| Williams, M | 1 |
| Earl, HM | 1 |
| Burnet, NG | 1 |
| Hatcher, H | 1 |
| Faoro, D | 1 |
| von Bueren, AO | 2 |
| Shalaby, T | 1 |
| Sciuscio, D | 1 |
| Hürlimann, ML | 1 |
| Arnold, L | 1 |
| Gerber, NU | 1 |
| Haybaeck, J | 1 |
| Mittelbronn, M | 1 |
| Hegi, M | 1 |
| Grotzer, MA | 1 |
| Shinwari, Z | 2 |
| Al-Hindi, H | 1 |
| Al-Shail, E | 1 |
| Khafaga, Y | 1 |
| Al-Kofide, A | 1 |
| El-Kum, N | 1 |
| Aboussekhra, A | 2 |
| Smith, RL | 1 |
| Shi, X | 1 |
| Estlin, EJ | 1 |
| Packer, RJ | 6 |
| Zhou, T | 1 |
| Holmes, E | 1 |
| Vezina, G | 2 |
| Gajjar, A | 2 |
| Friedrich, C | 1 |
| von Hoff, K | 1 |
| Kwiecien, R | 1 |
| Deinlein, F | 1 |
| Kuehl, J | 1 |
| Sachivko, NV | 1 |
| Konoplia, NE | 1 |
| Petrovich, SV | 1 |
| Sharak, EV | 1 |
| Xu, W | 1 |
| Janss, A | 1 |
| Moshang, T | 1 |
| McLean, TW | 1 |
| Spreafico, F | 1 |
| Gandola, L | 1 |
| Cefalo, G | 1 |
| Mazza, E | 1 |
| Landonio, G | 1 |
| Pignoli, E | 1 |
| Terenziani, M | 1 |
| Pedrazzoli, P | 1 |
| Siena, S | 1 |
| Fossati-Bellani, F | 1 |
| Cakar, M | 1 |
| Aksoy, S | 1 |
| Kilickap, S | 1 |
| Harputluoglu, H | 1 |
| Erman, M | 1 |
| Stiefel, M | 1 |
| Reiss, T | 1 |
| Staege, MS | 1 |
| Rengelshausen, J | 1 |
| Burhenne, J | 1 |
| Wawer, A | 1 |
| Foell, JL | 1 |
| Rutkauskiene, G | 1 |
| Labanauskas, L | 1 |
| Rorke-Adams, L | 1 |
| Burger, PC | 1 |
| Robertson, PL | 1 |
| Bayer, L | 1 |
| LaFond, D | 1 |
| Donahue, BR | 1 |
| Marymont, MH | 1 |
| Muraszko, K | 2 |
| Langston, J | 1 |
| Sposto, R | 2 |
| Santos, MA | 1 |
| Viégas, CM | 1 |
| Servidoni, RA | 1 |
| Barros, MH | 1 |
| Pinel, MI | 1 |
| Araújo, CM | 1 |
| Glas, M | 1 |
| Hennemann, B | 1 |
| Hirschmann, B | 1 |
| Marienhagen, J | 1 |
| Schmidt-Wolf, I | 1 |
| Manogaran, PS | 1 |
| Alrokayan, SA | 1 |
| Al-Hussein, KA | 1 |
| Gill, P | 1 |
| Litzow, M | 1 |
| Buckner, J | 1 |
| Arndt, C | 1 |
| Moynihan, T | 1 |
| Christianson, T | 1 |
| Ansell, S | 1 |
| Galanis, E | 1 |
| Bellani, FF | 1 |
| Gasparini, M | 1 |
| Lombardi, F | 1 |
| Zucali, R | 1 |
| Luccarelli, G | 1 |
| Migliavacca, F | 1 |
| Moise, S | 1 |
| Nicola, G | 1 |
| Cibinel, G | 1 |
| Cordero di Montezemolo, L | 1 |
| Soffietti, R | 1 |
| Pastore, G | 1 |
| Sciolla, R | 1 |
| Mosso, ML | 1 |
| Schiffer, D | 1 |
| Sicuro, L | 1 |
| Madon, E | 2 |
| Gerosa, MA | 1 |
| di Stefano, E | 1 |
| Olivi, A | 1 |
| Carteri, A | 1 |
| Pezzotta, S | 2 |
| Knerich, R | 1 |
| Butti, G | 1 |
| Casotto, A | 1 |
| Buoncristiani, P | 1 |
| Jereb, B | 1 |
| Reid, A | 1 |
| Ahuja, RK | 1 |
| Dent, RG | 1 |
| Seiler, RW | 2 |
| Bernasconi, S | 1 |
| Berchtold, W | 1 |
| Feldges, A | 1 |
| Imbach, P | 2 |
| Lüthi, A | 1 |
| Plüss, HJ | 1 |
| Vassella, F | 2 |
| Wyss, M | 1 |
| Wagner, HP | 2 |
| Sutton, LN | 3 |
| Elterman, R | 1 |
| Lange, B | 1 |
| Goldwein, J | 2 |
| Nicholson, HS | 2 |
| Mulne, L | 1 |
| Boyett, J | 1 |
| D'Angio, G | 2 |
| Wechsler-Jentzsch, K | 1 |
| Grabenbauer, GG | 1 |
| Löhnert, C | 1 |
| Erhardt, J | 1 |
| Buchfelder, M | 1 |
| Neubauer, U | 1 |
| Beck, JD | 1 |
| Reitz, S | 1 |
| Seyer, H | 1 |
| Thierauf, P | 1 |
| Fietkau, R | 1 |
| Urban, C | 1 |
| Benesch, M | 1 |
| Pakisch, B | 1 |
| Lackner, H | 1 |
| Kerbl, R | 1 |
| Schwinger, W | 1 |
| Oberbauer, R | 1 |
| Bethune, C | 1 |
| Blum, A | 1 |
| Geyer, JR | 2 |
| Silber, JR | 1 |
| Ho, RJ | 1 |
| Vezina, LG | 1 |
| Allen, JC | 1 |
| Ris, MD | 1 |
| Rorke, LB | 2 |
| Wara, WM | 1 |
| Cohen, BH | 1 |
| Boyett, JM | 1 |
| Lewandowicz, GM | 1 |
| Harding, B | 1 |
| Harkness, W | 1 |
| Hayward, R | 1 |
| Thomas, DG | 1 |
| Darling, JL | 1 |
| Greenberg, HS | 1 |
| Chamberlain, MC | 1 |
| Glantz, MJ | 1 |
| Wang, S | 1 |
| Noël, G | 1 |
| Mazeron, JJ | 1 |
| Ricardi, U | 1 |
| Corrias, A | 1 |
| Einaudi, S | 1 |
| Genitori, L | 1 |
| Sandri, A | 1 |
| di Montezemolo, LC | 1 |
| Besenzon, L | 1 |
| Urgesi, A | 1 |
| Kochi, M | 1 |
| Ushio, Y | 1 |
| Wilson, CB | 4 |
| Gutin, P | 1 |
| Boldrey, EB | 1 |
| Drafts, D | 1 |
| Levin, VA | 4 |
| Enot, KJ | 1 |
| Ertel, IJ | 2 |
| Boesel, C | 1 |
| Paoletti, P | 1 |
| Fumagalli, R | 1 |
| Weiss, JF | 1 |
| Crafts, DC | 1 |
| Edwards, MS | 1 |
| Pischer, TL | 1 |
| Ward, HW | 1 |
| Pompili, A | 1 |
| Cianfriglia, F | 1 |
| Occhipinti, E | 1 |
| Bloom, HJ | 2 |
| Neidhardt, MK | 1 |
| Terheggen, HG | 1 |
| Garrett, MJ | 1 |
| Hughes, HJ | 1 |
| Ryall, RD | 1 |
| Boratyński, W | 1 |
| Tait, DM | 1 |
| Thornton-Jones, H | 1 |
| Lemerle, J | 1 |
| Morris-Jones, P | 1 |
| Lefkowitz, IB | 1 |
| Siegel, KR | 2 |
| Schut, L | 2 |
| Evans, AE | 3 |
| Jenkin, RD | 1 |
| Ortega, JA | 1 |
| Wara, W | 1 |
| Kramer, S | 1 |
| Chang, CH | 1 |
| Leikin, SL | 1 |
| Pendergrass, TW | 1 |
| Milstein, JM | 1 |
| Mulne, AF | 1 |
| Kosnik, EJ | 1 |
| Morris, JD | 1 |
| Heideman, RL | 1 |
| Ruymann, FB | 1 |
| Stuntz, JT | 1 |
| Bleyer, WA | 1 |
| Hughes, EN | 1 |
| Shillito, J | 1 |
| Sallan, SE | 1 |
| Loeffler, JS | 1 |
| Cassady, JR | 1 |
| Tarbell, NJ | 1 |
| Bunin, GR | 1 |
| Chastagner, P | 1 |
| Olive, D | 1 |
| Philip, T | 1 |
| Zucker, JM | 1 |
| Czorny, A | 1 |
| Lapras, C | 1 |
| Brunat-Mentigny, M | 1 |
| Oi, S | 1 |
| Matsumoto, S | 1 |
| Raimondi, AJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Multi-Institutional Pilot Study of Allogeneic Hematopoietic Stem Cell Transplantation for Patients With Malignant Neuro-Epithelial and Other Solid Tumors[NCT02653196] | Early Phase 1 | 1 participants (Actual) | Interventional | 2015-09-30 | Terminated (stopped due to The Principal Investigator left the institution.) | ||
| An International, Randomized, Open-label Phase I/II Study of Vismodegib in Combination With Temozolomide Versus Temozolomide Alone in Adult Patients With Recurrent or Refractory Medulloblastomas Presenting an Activation of the Sonic Hedgehog (SHH) Pathway[NCT01601184] | Phase 1/Phase 2 | 24 participants (Actual) | Interventional | 2012-06-30 | Terminated (stopped due to The number of successes is not reached at the end of first stage of the phase II. The study is stopped.) | ||
| Phase III Prospective Randomized Study of Craniospinal RT Followed by One of Two Adjuvant Chemotherapy Regimens (CCNU, CDDP, VCR OR CPM, CDDP, VCR) for Newly-Diagnosed Average Risk MedulloblastomaMEDULLOBLASTOMA[NCT00002875] | Phase 3 | 421 participants (Actual) | Interventional | 1996-12-31 | Completed | ||
| Phase I/II Study of Lutathera in Pediatric and Young Adult Patients With Recurrent and/or Progressive High-Grade Central Nervous System Tumors and Meningiomas That Express Somatostatin Type2A Receptors and Demonstrate Uptake on DOTATATE PET[NCT05278208] | Phase 1/Phase 2 | 65 participants (Anticipated) | Interventional | 2022-11-21 | Recruiting | ||
| Does Varenicline Influence Alcohol Consumption in Alcohol Dependent Individuals?[NCT00846859] | Phase 2 | 162 participants (Actual) | Interventional | 2009-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for lomustine and Arachnoidal Cerebellar Sarcoma, Circumscribed
| Article | Year |
|---|---|
Medulloblastomas and central nervous system primitive neuroectodermal tumors.
Topics: Antineoplastic Agents; Central Nervous System Neoplasms; Cerebellar Neoplasms; Cisplatin; Cyclophosp | 2003 |
Adult medulloblastoma: multiagent chemotherapy.
Topics: Abdominal Pain; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cerebrospinal Flu | 2001 |
[Chemo-radiotherapy for malignant brain tumors].
Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Central Nervous System | 2002 |
Chemotherapy: the agents in current use.
Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Dacarbazine; Drug Therapy, Combination; Glioma; | 1975 |
Chemotherapy of primary brain tumors.
Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Brain Stem; Child; Efl | 1985 |
13 trials available for lomustine and Arachnoidal Cerebellar Sarcoma, Circumscribed
| Article | Year |
|---|---|
Multicenter pilot study of radiochemotherapy as first-line treatment for adults with medulloblastoma (NOA-07).
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Neoplasms; Chemoradiotherapy; Chem | 2018 |
Hyperfractionated Accelerated Radiotherapy (HART) with maintenance chemotherapy for metastatic (M1-3) Medulloblastoma--a safety/feasibility study.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Neoplasms; Chemoradiotherapy; | 2014 |
Neuropsychological Outcome of Children Treated for Standard Risk Medulloblastoma in the PNET4 European Randomized Controlled Trial of Hyperfractionated Versus Standard Radiation Therapy and Maintenance Chemotherapy.
Topics: Adolescent; Age Factors; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Cereb | 2015 |
Non-pineal supratentorial primitive neuro-ectodermal tumors (sPNET) in teenagers and young adults: Time to reconsider cisplatin based chemotherapy after cranio-spinal irradiation?
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Neoplasms; Child; Cisp | 2009 |
Survival and secondary tumors in children with medulloblastoma receiving radiotherapy and adjuvant chemotherapy: results of Children's Oncology Group trial A9961.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Neoplasms; Chemoradiot | 2013 |
Phase III study of craniospinal radiation therapy followed by adjuvant chemotherapy for newly diagnosed average-risk medulloblastoma.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Neoplasms; Chemotherap | 2006 |
Phase III study of craniospinal radiation therapy followed by adjuvant chemotherapy for newly diagnosed average-risk medulloblastoma.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Neoplasms; Chemotherap | 2006 |
Phase III study of craniospinal radiation therapy followed by adjuvant chemotherapy for newly diagnosed average-risk medulloblastoma.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Neoplasms; Chemotherap | 2006 |
Phase III study of craniospinal radiation therapy followed by adjuvant chemotherapy for newly diagnosed average-risk medulloblastoma.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Neoplasms; Chemotherap | 2006 |
Phase III study of craniospinal radiation therapy followed by adjuvant chemotherapy for newly diagnosed average-risk medulloblastoma.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Neoplasms; Chemotherap | 2006 |
Phase III study of craniospinal radiation therapy followed by adjuvant chemotherapy for newly diagnosed average-risk medulloblastoma.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Neoplasms; Chemotherap | 2006 |
Phase III study of craniospinal radiation therapy followed by adjuvant chemotherapy for newly diagnosed average-risk medulloblastoma.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Neoplasms; Chemotherap | 2006 |
Phase III study of craniospinal radiation therapy followed by adjuvant chemotherapy for newly diagnosed average-risk medulloblastoma.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Neoplasms; Chemotherap | 2006 |
Phase III study of craniospinal radiation therapy followed by adjuvant chemotherapy for newly diagnosed average-risk medulloblastoma.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Neoplasms; Chemotherap | 2006 |
Multidisciplinary treatment of medulloblastoma: a 5-year experience with the SIOP trial.
Topics: Adolescent; Cerebellar Neoplasms; Child; Child, Preschool; Clinical Trials as Topic; Drug Therapy, C | 1981 |
Chemotherapy for medulloblastoma in children. Current status and future prospects.
Topics: Adolescent; Cerebellar Neoplasms; Child; Child, Preschool; Clinical Trials as Topic; Drug Therapy, C | 1982 |
Outcome for children with medulloblastoma treated with radiation and cisplatin, CCNU, and vincristine chemotherapy.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Neoplasms; Chemotherap | 1994 |
Synchronous radiochemotherapy in unfavorable brain tumors of children and young adults.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Che | 1998 |
Treatment of children with medulloblastomas with reduced-dose craniospinal radiation therapy and adjuvant chemotherapy: A Children's Cancer Group Study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cerebellar Neoplasms; Chemotherapy, Adjuvant; Child; | 1999 |
Adjuvant chemotherapy for medulloblastoma: the first multi-centre control trial of the International Society of Paediatric Oncology (SIOP I).
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Neoplasms; Child; Child, Pres | 1990 |
The treatment of medulloblastoma. Results of a prospective randomized trial of radiation therapy with and without CCNU, vincristine, and prednisone.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Neoplasms; Child; Child, Pres | 1990 |
44 other studies available for lomustine and Arachnoidal Cerebellar Sarcoma, Circumscribed
| Article | Year |
|---|---|
Estrogen and soy isoflavonoids decrease sensitivity of medulloblastoma and central nervous system primitive neuroectodermal tumor cells to chemotherapeutic cytotoxicity.
Topics: Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Cisplatin; Equol; Estradiol | 2017 |
Treatment-induced remission of medulloblastoma using a chemotherapeutic regimen devoid of vincristine in a child with Charcot-Marie-Tooth disease.
Topics: Antineoplastic Agents; Carboplatin; Cerebellar Neoplasms; Charcot-Marie-Tooth Disease; Chemoradiothe | 2019 |
Expression of O⁶-methylguanine-DNA methyltransferase in childhood medulloblastoma.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Cell Proliferation; C | 2011 |
Response of medulloblastoma cells to vincristine and lomustine: role of TRKC, CTNNB1 and STK15.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Aurora Kinase A; Aurora Kinases; b | 2011 |
Chemotherapy dose-intensity and survival for childhood medulloblastoma.
Topics: Adolescent; Antineoplastic Agents; Cerebellar Neoplasms; Child; Child, Preschool; Cisplatin; Clinica | 2012 |
Treatment of adult nonmetastatic medulloblastoma patients according to the paediatric HIT 2000 protocol: a prospective observational multicentre study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Neoplasms; Chemotherapy, Adj | 2013 |
[Role of adjuvant chemotherapy in the treatment of medulloblastoma in children].
Topics: Adolescent; Age Factors; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Carboplatin; Cere | 2002 |
Adult height and adult sitting height in childhood medulloblastoma survivors.
Topics: Adolescent; Adult; Age of Onset; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogeni | 2003 |
Survival of adults treated for medulloblastoma using paediatric protocols.
Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cerebellar | 2005 |
Procarbazine, lomustine, vincristine combination may be effective in adult medulloblastoma patients with systemic metastases.
Topics: Adult; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; | 2005 |
Successful treatment with voriconazole of Aspergillus brain abscess in a boy with medulloblastoma.
Topics: Administration, Oral; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Aspergillus | 2007 |
Treatment of patients of high-risk group of medulloblastoma with the adjuvant lomustine, cisplatin, and vincristine chemotherapy.
Topics: Adolescent; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytoge | 2005 |
Timing of radiation in children with medulloblastoma/PNET.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Neoplasms; Child; Child, Pres | 2007 |
Complete response after treatment with a somatostatin analogue in an adult patient with recurrent medulloblastoma.
Topics: Adult; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Brain Stem N | 2008 |
Vincristine and lomustine induce apoptosis and p21(WAF1) up-regulation in medulloblastoma and normal human epithelial and fibroblast cells.
Topics: Antineoplastic Agents; Apoptosis; bcl-X Protein; Cell Cycle; Cell Line; Cerebellar Neoplasms; Cyclin | 2008 |
High-dose chemotherapy with autologous stem cell transplantation in adults with recurrent embryonal tumors of the central nervous system.
Topics: Adult; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; | 2008 |
Medulloblastoma. Results of a sequential combined treatment.
Topics: Adolescent; Adult; Cerebellar Neoplasms; Child; Child, Preschool; Combined Modality Therapy; Female; | 1984 |
[Long-term results of the treatment of infantile medulloblastoma].
Topics: Cerebellar Neoplasms; Child; Child, Preschool; Cobalt Radioisotopes; Female; Follow-Up Studies; Huma | 1983 |
Medulloblastoma in childhood. Multidisciplinary treatment.
Topics: Adolescent; Carmustine; Cerebellar Neoplasms; Cerebellum; Child; Child, Preschool; Female; Humans; I | 1982 |
Patterns of failure in patients with medulloblastoma.
Topics: Adolescent; Adult; Aged; Cerebellar Neoplasms; Child; Child, Preschool; Cyclophosphamide; Dose-Respo | 1982 |
Fatal pulmonary toxic effects of lomustine.
Topics: Cerebellar Neoplasms; Humans; Lomustine; Lung Diseases; Male; Medulloblastoma; Middle Aged; Nitrosou | 1982 |
Adjuvant chemotherapy with procarbazine, vincristine and prednisone for medulloblastomas. A preliminary report.
Topics: Cerebellar Neoplasms; Child; Drug Therapy, Combination; Humans; Lomustine; Medulloblastoma; Postoper | 1981 |
[Medulloblastomas--the results after postoperative radiotherapy with and without adjuvant chemotherapy].
Topics: Actuarial Analysis; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Ne | 1993 |
Lipid association increases the potency against primary medulloblastoma cells and systemic exposure of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) in rats.
Topics: Animals; Antineoplastic Agents, Alkylating; Cell Division; Dimyristoylphosphatidylcholine; Drug Carr | 1999 |
Chemosensitivity in childhood brain tumours in vitro: evidence of differential sensitivity to lomustine (CCNU) and vincristine.
Topics: Adult; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Child; Dose-Response Relationship, Drug; | 2000 |
[Post-operative neoadjuvant chemotherapy before radiotherapy as compared to immediate radiotherapy followed by maintenance chemotherapy in the treatment of medulloblastoma in childhood: results of German prospective randomised trial HIT'91].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Adjuvant; | 2001 |
Thyroid dysfunction as a late effect in childhood medulloblastoma: a comparison of hyperfractionated versus conventionally fractionated craniospinal radiotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Child; Child, Preschool; Com | 2001 |
Single-agent chemotherapy of brain tumors. A five-year review.
Topics: Astrocytoma; Bone Marrow Diseases; Brain Neoplasms; Carmustine; Glioma; Humans; Imidazoles; Lomustin | 1976 |
Brain tumors in children.
Topics: Adolescent; Astrocytoma; Brain; Brain Neoplasms; Child; Diagnosis, Differential; Ependymoma; Female; | 1978 |
Adjuvant chemotherapy with intraventricular methotrexate and CCNU after surgery and radiotherapy of medulloblastomas.
Topics: Brain Neoplasms; Humans; Injections, Spinal; Lomustine; Medulloblastoma; Methotrexate; Nitrosourea C | 1978 |
Desmosterol: a biochemical marker of glioma growth.
Topics: Astrocytoma; Brain Neoplasms; Carmustine; Cholesterol; Chromatography, Gas; Desmosterol; Diagnosis, | 1977 |
Chemotherapy of recurrent medulloblastoma with combined procarbazine, CCNU, and vincristine.
Topics: Adolescent; Adult; Brain Neoplasms; Child; Child, Preschool; Drug Therapy, Combination; Humans; Lomu | 1978 |
Central nervous system tumors of childhood treated with CCNU, vincristine, and radiation.
Topics: Adolescent; Astrocytoma; Bone Marrow; Brain Neoplasms; Child; Child, Preschool; Drug Therapy, Combin | 1978 |
[Some preliminary observations on chemotherapy of infantile medulloblastomas with vincristine sulfate and 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU)].
Topics: Age Factors; Cerebellar Neoplasms; Child; Drug Evaluation; Drug Therapy, Combination; Female; Humans | 1978 |
[Interim results of the SIOP study (author's transl)].
Topics: Adolescent; Brain Neoplasms; Child; Ependymoma; Humans; Lomustine; Medulloblastoma; Methods; Vincris | 1978 |
[Therapy of medulloblastoma and ependymoma in childhood].
Topics: Age Factors; Brain Neoplasms; Child; Child, Preschool; Ependymoma; Humans; Infant; Lomustine; Medull | 1977 |
CCNU in brain tumours.
Topics: Adolescent; Adult; Brain Neoplasms; Bronchial Neoplasms; Cerebellar Neoplasms; Child, Preschool; Fem | 1975 |
[Results of combined treatment of neoplasms of the posterior cranial fossa in children].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Cerebellar Neoplasms; Child | 1992 |
Results of treatment of children with recurrent medulloblastoma/primitive neuroectodermal tumors with lomustine, cisplatin, and vincristine.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Neoplasms; Child; Child, Pres | 1990 |
Eight drugs in one day chemotherapy for brain tumors: experience in 107 children and rationale for preradiation chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Child; Cisplatin; Comb | 1987 |
Medulloblastoma at the joint center for radiation therapy between 1968 and 1984. The influence of radiation dose on the patterns of failure and survival.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cerebellar Neoplasms; | 1988 |
Efficacy of adjuvant chemotherapy for patients with poor-risk medulloblastoma: a preliminary report.
Topics: Adolescent; Adult; Brain Neoplasms; Child; Child, Preschool; Cisplatin; Combined Modality Therapy; D | 1988 |
[Efficacy of the "8 drugs in a day" protocol in brain tumors in children].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Cer | 1988 |
[Brain tumors in infants and children--factors affecting prognosis, (Part-3). Mode of metastasis and prognosis in medulloblastoma].
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Brain Stem; Cerebellar Neoplasms; C | 1985 |