lomustine has been researched along with Acute Liver Injury, Drug-Induced in 13 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " No association between dosing frequency, cumulative dose, initial starting dose or concurrent medications, and increases in ALT were found." | 1.38 | Low apparent risk of CCNU (lomustine)-associated clinical hepatotoxicity in cats. ( Chretin, JD; Musser, ML; Quinn, HT, 2012) |
| "In 4 years (1993-1996) 206 pts." | 1.31 | Venoocclusive liver disease (VOD) as a complication of Wilms' tumour management in the series of consecutive 206 patients. ( Czauderna, P; Godziński, J; Katski, K; Kowalczyk, J; Kurylak, A; Lopatka, B; Sawicz-Birkowska, K; Skotnicka-Klonowicz, G, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (30.77) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 5 (38.46) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fourches, D | 1 |
| Barnes, JC | 1 |
| Day, NC | 1 |
| Bradley, P | 1 |
| Reed, JZ | 1 |
| Tropsha, A | 1 |
| Liu, Z | 1 |
| Shi, Q | 1 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Fang, H | 1 |
| Tong, W | 2 |
| Morgan, RE | 1 |
| van Staden, CJ | 1 |
| Chen, Y | 1 |
| Kalyanaraman, N | 1 |
| Kalanzi, J | 1 |
| Dunn, RT | 1 |
| Afshari, CA | 1 |
| Hamadeh, HK | 1 |
| Chen, M | 1 |
| Suzuki, A | 1 |
| Thakkar, S | 1 |
| Yu, K | 1 |
| Hu, C | 1 |
| Hosoya, K | 1 |
| Lord, LK | 1 |
| Lara-Garcia, A | 1 |
| Kisseberth, WC | 1 |
| London, CA | 1 |
| Couto, CG | 1 |
| Musser, ML | 1 |
| Quinn, HT | 1 |
| Chretin, JD | 1 |
| Gadjeva, V | 1 |
| Tolekova, A | 1 |
| Vasileva, M | 1 |
| Urban, C | 1 |
| Benesch, M | 1 |
| Pakisch, B | 1 |
| Lackner, H | 1 |
| Kerbl, R | 1 |
| Schwinger, W | 1 |
| Oberbauer, R | 1 |
| Czauderna, P | 1 |
| Katski, K | 1 |
| Kowalczyk, J | 1 |
| Kurylak, A | 1 |
| Lopatka, B | 1 |
| Skotnicka-Klonowicz, G | 1 |
| Sawicz-Birkowska, K | 1 |
| Godziński, J | 1 |
| Ahmed, AE | 2 |
| Grissom, M | 1 |
| el-Azhary, R | 1 |
| Haque, A | 1 |
| Boor, PJ | 2 |
| Costanzi, J | 1 |
| Viotte, G | 2 |
| Lahouel, M | 2 |
| Ducastelle, T | 2 |
| Sumereau, E | 1 |
| Morin, JP | 1 |
| Hemet, J | 2 |
| Fillastre, JP | 2 |
| Kretschmer, NW | 1 |
| el Azhary, RA | 1 |
| Reynolds, ES | 1 |
1 review available for lomustine and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr | 2016 |
1 trial available for lomustine and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Synchronous radiochemotherapy in unfavorable brain tumors of children and young adults.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Che | 1998 |
11 other studies available for lomustine and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI | 2010 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily | 2013 |
Prevalence of elevated alanine transaminase activity in dogs treated with CCNU (Lomustine)*.
Topics: Alanine Transaminase; Animals; Antineoplastic Agents; Chemical and Drug Induced Liver Injury; Dog Di | 2009 |
Low apparent risk of CCNU (lomustine)-associated clinical hepatotoxicity in cats.
Topics: Alanine Transaminase; Animals; Antineoplastic Agents, Alkylating; Cat Diseases; Cats; Chemical and D | 2012 |
Effect of the spin-labelled 1-ethyl-1-nitrosourea on CCNU-induced oxidative liver injury.
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Antioxidants; Catalase; Chemical and Drug Induced | 2007 |
Venoocclusive liver disease (VOD) as a complication of Wilms' tumour management in the series of consecutive 206 patients.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cause of Death; Chemical and Drug Induce | 2000 |
Studies on the mechanism of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU)-induced hepatotoxicity. II. Biochemical and morphological characterization of the injury and its prevention by phenobarbital.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bile; Chemical and Drug Induced Liver In | 1987 |
[Hepatotoxicity of (chloro-2-ethyl)-1-cyclohexyl-3-nitroso-1-urea (CCNU) in the rat].
Topics: Alkaline Phosphatase; Animals; Bilirubin; Body Weight; Chemical and Drug Induced Liver Injury; Edema | 1986 |
[Hepatopathy with a progressive course after one-time administration of (chloro-2-ethyl)-1-cyclohexyl-3-nitroso-1-uréa (CCNU) in rats].
Topics: Animals; Chemical and Drug Induced Liver Injury; Female; Liver; Lomustine; Rats; Rats, Inbred Strain | 1987 |
Studies on the mechanism of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU)-induced hepatotoxicity. III. Ultrastructural characterization of bile duct injury.
Topics: Animals; Bile Ducts; Bile Ducts, Intrahepatic; Chemical and Drug Induced Liver Injury; Liver Disease | 1987 |