lomerizine has been researched along with Nerve Degeneration in 7 studies
lomerizine: used to treat migraines
Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Following partial optic nerve transection, hyper-phosphorylation of Tau and acetylated tubulin immunoreactivity were increased, and Nogo-A immunoreactivity was decreased, indicating that axonal changes occurred acutely." | 1.46 | Specific ion channels contribute to key elements of pathology during secondary degeneration following neurotrauma. ( Bartlett, CA; Chiha, W; Fitzgerald, M; Giacci, MK; Harvey, AR; Hodgetts, SI; O'Hare Doig, RL; Smith, NM; Yates, NJ, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Toomey, LM | 3 |
| Bartlett, CA | 5 |
| Gavriel, N | 2 |
| McGonigle, T | 1 |
| Majimbi, M | 2 |
| Gopalasingam, G | 2 |
| Rodger, J | 2 |
| Fitzgerald, M | 6 |
| O'Hare Doig, RL | 2 |
| Chiha, W | 1 |
| Giacci, MK | 2 |
| Yates, NJ | 1 |
| Smith, NM | 2 |
| Hodgetts, SI | 1 |
| Harvey, AR | 2 |
| Milbourn, HR | 1 |
| Gray, CGG | 1 |
| Gough, AH | 1 |
| Fehily, B | 1 |
| Savigni, DL | 1 |
| Szymanski, CR | 1 |
| Lozić, I | 1 |
| Ito, Y | 1 |
| Nakamura, S | 1 |
| Tanaka, H | 1 |
| Tsuruma, K | 1 |
| Shimazawa, M | 1 |
| Araie, M | 1 |
| Hara, H | 1 |
| Selt, M | 1 |
| Dunlop, SA | 1 |
1 review available for lomerizine and Nerve Degeneration
| Article | Year |
|---|---|
Limiting oxidative stress following neurotrauma with a combination of ion channel inhibitors.
Topics: Animals; Calcium; Central Nervous System; Humans; Imidazoles; Myelin Sheath; Nerve Degeneration; Oxi | 2017 |
6 other studies available for lomerizine and Nerve Degeneration
| Article | Year |
|---|---|
Comparing modes of delivery of a combination of ion channel inhibitors for limiting secondary degeneration following partial optic nerve transection.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Drug Therapy, Combination; Female; Imidazoles; | 2019 |
Specific ion channels contribute to key elements of pathology during secondary degeneration following neurotrauma.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Disease Models, Animal; Female; Imidazoles; Mac | 2017 |
Comparison of ion channel inhibitor combinations for limiting secondary degeneration following partial optic nerve transection.
Topics: Animals; Calcium Channel Blockers; Calcium-Binding Proteins; Cell Adhesion Molecules, Neuronal; Dise | 2019 |
Three Ca2+ channel inhibitors in combination limit chronic secondary degeneration following neurotrauma.
Topics: Adenosine Triphosphate; Animals; Basic Helix-Loop-Helix Transcription Factors; Calcium Channel Block | 2013 |
Lomerizine, a Ca2+ channel blocker, protects against neuronal degeneration within the visual center of the brain after retinal damage in mice.
Topics: Animals; Calcium Channel Blockers; Disease Models, Animal; Geniculate Bodies; Male; Mice; Mice, Inbr | 2010 |
Limited restoration of visual function after partial optic nerve injury; a time course study using the calcium channel blocker lomerizine.
Topics: Animals; Calcium Channel Blockers; Cell Count; Cell Survival; Female; Immunohistochemistry; Macropha | 2010 |