Page last updated: 2024-10-30

lomerizine and Cranial Nerve II Injuries

lomerizine has been researched along with Cranial Nerve II Injuries in 8 studies

lomerizine: used to treat migraines

Research Excerpts

ExcerptRelevanceReference
"Following partial optic nerve transection, hyper-phosphorylation of Tau and acetylated tubulin immunoreactivity were increased, and Nogo-A immunoreactivity was decreased, indicating that axonal changes occurred acutely."1.46Specific ion channels contribute to key elements of pathology during secondary degeneration following neurotrauma. ( Bartlett, CA; Chiha, W; Fitzgerald, M; Giacci, MK; Harvey, AR; Hodgetts, SI; O'Hare Doig, RL; Smith, NM; Yates, NJ, 2017)
"Partial optic nerve transection is an excellent model in which to unequivocally differentiate events occurring during secondary degeneration from those resulting from primary CNS injury."1.35Secondary degeneration of the optic nerve following partial transection: the benefits of lomerizine. ( Bartlett, CA; Dunlop, SA; Evill, L; Fitzgerald, M; Harvey, AR; Rodger, J, 2009)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (37.50)29.6817
2010's5 (62.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Toomey, LM2
Bartlett, CA7
Gavriel, N1
McGonigle, T1
Majimbi, M2
Gopalasingam, G2
Rodger, J3
Fitzgerald, M7
O'Hare Doig, RL2
Chiha, W1
Giacci, MK1
Yates, NJ1
Smith, NM2
Hodgetts, SI1
Harvey, AR4
Savigni, DL1
Szymanski, CR1
Lozić, I1
Evill, L2
Dunlop, SA3
Payne, SC1
Selt, M1
Karim, Z1
Sawada, A1
Kawakami, H1
Yamamoto, T1
Taniguchi, T1

Other Studies

8 other studies available for lomerizine and Cranial Nerve II Injuries

ArticleYear
Comparing modes of delivery of a combination of ion channel inhibitors for limiting secondary degeneration following partial optic nerve transection.
    Scientific reports, 2019, 10-25, Volume: 9, Issue:1

    Topics: Animals; Calcium Channel Blockers; Calcium Channels; Drug Therapy, Combination; Female; Imidazoles;

2019
Specific ion channels contribute to key elements of pathology during secondary degeneration following neurotrauma.
    BMC neuroscience, 2017, 08-14, Volume: 18, Issue:1

    Topics: Animals; Calcium Channel Blockers; Calcium Channels; Disease Models, Animal; Female; Imidazoles; Mac

2017
Comparison of ion channel inhibitor combinations for limiting secondary degeneration following partial optic nerve transection.
    Experimental brain research, 2019, Volume: 237, Issue:1

    Topics: Animals; Calcium Channel Blockers; Calcium-Binding Proteins; Cell Adhesion Molecules, Neuronal; Dise

2019
Three Ca2+ channel inhibitors in combination limit chronic secondary degeneration following neurotrauma.
    Neuropharmacology, 2013, Volume: 75

    Topics: Adenosine Triphosphate; Animals; Basic Helix-Loop-Helix Transcription Factors; Calcium Channel Block

2013
Secondary degeneration of the optic nerve following partial transection: the benefits of lomerizine.
    Experimental neurology, 2009, Volume: 216, Issue:1

    Topics: Animals; Axons; Calcium Channel Blockers; Calcium Channels, L-Type; Disease Models, Animal; Female;

2009
Secondary retinal ganglion cell death and the neuroprotective effects of the calcium channel blocker lomerizine.
    Investigative ophthalmology & visual science, 2009, Volume: 50, Issue:11

    Topics: Animals; Calcium Channel Blockers; Carbocyanines; Caspase 3; Cell Count; Cell Death; Cell Survival;

2009
Limited restoration of visual function after partial optic nerve injury; a time course study using the calcium channel blocker lomerizine.
    Brain research bulletin, 2010, Mar-16, Volume: 81, Issue:4-5

    Topics: Animals; Calcium Channel Blockers; Cell Count; Cell Survival; Female; Immunohistochemistry; Macropha

2010
A new calcium channel antagonist, lomerizine, alleviates secondary retinal ganglion cell death after optic nerve injury in the rat.
    Current eye research, 2006, Volume: 31, Issue:3

    Topics: Animals; Calcium Channel Blockers; Cell Count; Cell Death; Cell Survival; Male; Optic Nerve Injuries

2006