lomefloxacin and Leprosy
lomefloxacin has been researched along with Leprosy in 2 studies
lomefloxacin: structure given in first source
lomefloxacin : A fluoroquinolone antibiotic, used (generally as the hydrochloride salt) to treat bacterial infections including bronchitis and urinary tract infections. It is also used to prevent urinary tract infections prior to surgery.
Leprosy: A chronic granulomatous infection caused by MYCOBACTERIUM LEPRAE. The granulomatous lesions are manifested in the skin, the mucous membranes, and the peripheral nerves. Two polar or principal types are lepromatous and tuberculoid.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Previously, pefloxacin and ofloxacin were found to be active against Mycobacterium leprae in vitro, in experimental animals, and in clinical trials of lepromatous leprosy patients." | 3.68 | Activities of various quinolone antibiotics against Mycobacterium leprae in infected mice. ( Gelber, RH; Iranmanesh, A; Murray, L; Siu, P; Tsang, M, 1992) |
| " In a dosage of 150 mg/kg administered daily, A-56619 is active and A-56620 is inactive against M." | 1.28 | Anti-Mycobacterium leprae activity of several quinolones studied in the mouse. ( Pattyn, SR, 1991) |
Research
Studies (2)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Gelber, RH | 1 |
| Iranmanesh, A | 1 |
| Murray, L | 1 |
| Siu, P | 1 |
| Tsang, M | 1 |
| Pattyn, SR | 1 |
Other Studies
2 other studies available for lomefloxacin and Leprosy
| Article | Year |
|---|---|
Activities of various quinolone antibiotics against Mycobacterium leprae in infected mice.
Topics: Animals; Anti-Infective Agents; Female; Fluoroquinolones; Leprosy; Mice; Mice, Inbred BALB C; Mycoba | 1992 |
Anti-Mycobacterium leprae activity of several quinolones studied in the mouse.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Fleroxacin; Fluoroquinolones; Leprosy; Mice; Mycobact | 1991 |