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lomefloxacin and Leprosy

lomefloxacin has been researched along with Leprosy in 2 studies

lomefloxacin: structure given in first source
lomefloxacin : A fluoroquinolone antibiotic, used (generally as the hydrochloride salt) to treat bacterial infections including bronchitis and urinary tract infections. It is also used to prevent urinary tract infections prior to surgery.

Leprosy: A chronic granulomatous infection caused by MYCOBACTERIUM LEPRAE. The granulomatous lesions are manifested in the skin, the mucous membranes, and the peripheral nerves. Two polar or principal types are lepromatous and tuberculoid.

Research Excerpts

ExcerptRelevanceReference
"Previously, pefloxacin and ofloxacin were found to be active against Mycobacterium leprae in vitro, in experimental animals, and in clinical trials of lepromatous leprosy patients."3.68Activities of various quinolone antibiotics against Mycobacterium leprae in infected mice. ( Gelber, RH; Iranmanesh, A; Murray, L; Siu, P; Tsang, M, 1992)
" In a dosage of 150 mg/kg administered daily, A-56619 is active and A-56620 is inactive against M."1.28Anti-Mycobacterium leprae activity of several quinolones studied in the mouse. ( Pattyn, SR, 1991)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gelber, RH1
Iranmanesh, A1
Murray, L1
Siu, P1
Tsang, M1
Pattyn, SR1

Other Studies

2 other studies available for lomefloxacin and Leprosy

ArticleYear
Activities of various quinolone antibiotics against Mycobacterium leprae in infected mice.
    Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:11

    Topics: Animals; Anti-Infective Agents; Female; Fluoroquinolones; Leprosy; Mice; Mice, Inbred BALB C; Mycoba

1992
Anti-Mycobacterium leprae activity of several quinolones studied in the mouse.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1991, Volume: 59, Issue:4

    Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Fleroxacin; Fluoroquinolones; Leprosy; Mice; Mycobact

1991
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