lomefloxacin has been researched along with Kidney Failure, Chronic in 4 studies
lomefloxacin: structure given in first source
lomefloxacin : A fluoroquinolone antibiotic, used (generally as the hydrochloride salt) to treat bacterial infections including bronchitis and urinary tract infections. It is also used to prevent urinary tract infections prior to surgery.
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fluoroquinolones have similar chemical structures but wide differences in their pharmacokinetic profiles." | 2.38 | Influence of renal function on the pharmacokinetics of lomefloxacin compared with other fluoroquinolones. ( Blum, RA, 1992) |
| " For the other new quinolones, a decrease in glomerular filtration rate below 20-30 ml/min induces an increase in terminal half-life and a decrease in plasma and renal clearance, related to the degree of renal impairment." | 2.38 | Pharmacokinetics of quinolones in renal insufficiency. ( Borsa-Lebas, F; Dhib, M; Fillastre, JP; Humbert, G; Leroy, A; Moulin, B, 1990) |
| "Lomefloxacin was administered orally in a dose of 400 mg at an interval of 48 hours 24 hours prior to the hemodialysis application." | 1.29 | [Lomefloxacin pharmacokinetics in patients in the terminal stage of chronic renal insufficiency, undergoing treatment with programmed hemodialysis]. ( Dvoretskiĭ, LI; Iakovlev, SV; Izotova, GN; Kolendo, SE; Miagkov, AV; Shvyreva, GS; Vorob'ev, PA, 1995) |
| " The terminal half-life was 7." | 1.28 | Lomefloxacin pharmacokinetics in subjects with normal and impaired renal function. ( Fillastre, JP; Humbert, G; Leroy, A, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kolendo, SE | 1 |
| Vorob'ev, PA | 1 |
| Dvoretskiĭ, LI | 1 |
| Izotova, GN | 1 |
| Miagkov, AV | 1 |
| Shvyreva, GS | 1 |
| Iakovlev, SV | 1 |
| Blum, RA | 1 |
| Fillastre, JP | 2 |
| Leroy, A | 2 |
| Moulin, B | 1 |
| Dhib, M | 1 |
| Borsa-Lebas, F | 1 |
| Humbert, G | 2 |
2 reviews available for lomefloxacin and Kidney Failure, Chronic
| Article | Year |
|---|---|
Influence of renal function on the pharmacokinetics of lomefloxacin compared with other fluoroquinolones.
Topics: Anti-Infective Agents; Creatinine; Fluoroquinolones; Humans; Kidney Failure, Chronic; Meta-Analysis | 1992 |
Pharmacokinetics of quinolones in renal insufficiency.
Topics: Anti-Infective Agents; Ciprofloxacin; Enoxacin; Fleroxacin; Fluoroquinolones; Glomerular Filtration | 1990 |
2 other studies available for lomefloxacin and Kidney Failure, Chronic
| Article | Year |
|---|---|
[Lomefloxacin pharmacokinetics in patients in the terminal stage of chronic renal insufficiency, undergoing treatment with programmed hemodialysis].
Topics: Anti-Infective Agents; Combined Modality Therapy; Fluoroquinolones; Humans; Kidney Failure, Chronic; | 1995 |
Lomefloxacin pharmacokinetics in subjects with normal and impaired renal function.
Topics: 4-Quinolones; Adult; Anti-Infective Agents; Female; Fluoroquinolones; Half-Life; Humans; Kidney Fail | 1990 |