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lomefloxacin and Keratitis

lomefloxacin has been researched along with Keratitis in 4 studies

lomefloxacin: structure given in first source
lomefloxacin : A fluoroquinolone antibiotic, used (generally as the hydrochloride salt) to treat bacterial infections including bronchitis and urinary tract infections. It is also used to prevent urinary tract infections prior to surgery.

Keratitis: Inflammation of the cornea.

Research Excerpts

ExcerptRelevanceReference
"3% lomefloxacin single agent solution, by comparing to a combination of fortified ophthalmic solutions of cefazolin sodium 50 mg/ml and gentamicin sulfate 14 mg/ml, in the treatment of acute bacterial keratitis."9.11Clinical evaluation of ophthalmic lomefloxacin 0.3% in comparison with fortified cefazolin and gentamicin ophthalmic solutions in the treatment of presumed bacterial keratitis. ( Erjongmanee, S; Kasetsuwan, N; Pariyakanok, L; Phusitphoykai, N; Puangsricharern, V, 2004)
"Lomefloxacin was compared with ciprofloxacin in different rabbit keratitis models."7.71Lomefloxacin is an effective treatment of experimental bacterial keratitis. ( Gordon, YJ; Kowalski, RP; Romanowski, EG; Yates, KA, 2001)
" This finding may be due to the somewhat lower initial degree of corneal inflammation in this group and suggests that the course of corneal recovery is predominately dependent on the initial degree of infection with both dosage regimens of lomefloxacin capable of eradicating corneal organisms."5.29Bacterial keratitis therapy in guinea pigs with lomefloxacin by initially high-followed by low-dosage regimen. ( Abalain, ML; Colin, J; Jauch, A; Malet, F, 1995)
"3% lomefloxacin single agent solution, by comparing to a combination of fortified ophthalmic solutions of cefazolin sodium 50 mg/ml and gentamicin sulfate 14 mg/ml, in the treatment of acute bacterial keratitis."5.11Clinical evaluation of ophthalmic lomefloxacin 0.3% in comparison with fortified cefazolin and gentamicin ophthalmic solutions in the treatment of presumed bacterial keratitis. ( Erjongmanee, S; Kasetsuwan, N; Pariyakanok, L; Phusitphoykai, N; Puangsricharern, V, 2004)
"The data on the use of the difluoroquinolone lomefloxacin in the treatment of ocular infections such as bacterial conjunctivitis and keratitis, ulcer of the cornea, uveitis, gonococcal and chlamydial conjunctivitis are presented."5.08[Lomefloxacin in treatment of infectious eye diseases]. ( Kononenko, LA; Maĭchuk, IuF; Vakhova, ES, 1998)
"Lomefloxacin was compared with ciprofloxacin in different rabbit keratitis models."3.71Lomefloxacin is an effective treatment of experimental bacterial keratitis. ( Gordon, YJ; Kowalski, RP; Romanowski, EG; Yates, KA, 2001)
" This finding may be due to the somewhat lower initial degree of corneal inflammation in this group and suggests that the course of corneal recovery is predominately dependent on the initial degree of infection with both dosage regimens of lomefloxacin capable of eradicating corneal organisms."1.29Bacterial keratitis therapy in guinea pigs with lomefloxacin by initially high-followed by low-dosage regimen. ( Abalain, ML; Colin, J; Jauch, A; Malet, F, 1995)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Erjongmanee, S1
Kasetsuwan, N1
Phusitphoykai, N1
Puangsricharern, V1
Pariyakanok, L1
Malet, F1
Colin, J1
Jauch, A1
Abalain, ML1
Maĭchuk, IuF1
Vakhova, ES1
Kononenko, LA1
Kowalski, RP1
Romanowski, EG1
Yates, KA1
Gordon, YJ1

Trials

2 trials available for lomefloxacin and Keratitis

ArticleYear
Clinical evaluation of ophthalmic lomefloxacin 0.3% in comparison with fortified cefazolin and gentamicin ophthalmic solutions in the treatment of presumed bacterial keratitis.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2004, Volume: 87 Suppl 2

    Topics: Acute Disease; Adolescent; Adult; Anti-Bacterial Agents; Cefazolin; Double-Blind Method; Female; Flu

2004
[Lomefloxacin in treatment of infectious eye diseases].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 1998, Volume: 43, Issue:10

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Conjuncti

1998

Other Studies

2 other studies available for lomefloxacin and Keratitis

ArticleYear
Bacterial keratitis therapy in guinea pigs with lomefloxacin by initially high-followed by low-dosage regimen.
    Ophthalmic research, 1995, Volume: 27, Issue:6

    Topics: Animals; Anti-Infective Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Fluo

1995
Lomefloxacin is an effective treatment of experimental bacterial keratitis.
    Cornea, 2001, Volume: 20, Issue:3

    Topics: Administration, Topical; Animals; Anti-Infective Agents; Bacteria; Ciprofloxacin; Colony Count, Micr

2001