lomefloxacin has been researched along with Chronic Kidney Failure in 4 studies
lomefloxacin: structure given in first source
lomefloxacin : A fluoroquinolone antibiotic, used (generally as the hydrochloride salt) to treat bacterial infections including bronchitis and urinary tract infections. It is also used to prevent urinary tract infections prior to surgery.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fluoroquinolones have similar chemical structures but wide differences in their pharmacokinetic profiles." | 2.38 | Influence of renal function on the pharmacokinetics of lomefloxacin compared with other fluoroquinolones. ( Blum, RA, 1992) |
| " For the other new quinolones, a decrease in glomerular filtration rate below 20-30 ml/min induces an increase in terminal half-life and a decrease in plasma and renal clearance, related to the degree of renal impairment." | 2.38 | Pharmacokinetics of quinolones in renal insufficiency. ( Borsa-Lebas, F; Dhib, M; Fillastre, JP; Humbert, G; Leroy, A; Moulin, B, 1990) |
| "Lomefloxacin was administered orally in a dose of 400 mg at an interval of 48 hours 24 hours prior to the hemodialysis application." | 1.29 | [Lomefloxacin pharmacokinetics in patients in the terminal stage of chronic renal insufficiency, undergoing treatment with programmed hemodialysis]. ( Dvoretskiĭ, LI; Iakovlev, SV; Izotova, GN; Kolendo, SE; Miagkov, AV; Shvyreva, GS; Vorob'ev, PA, 1995) |
| " The terminal half-life was 7." | 1.28 | Lomefloxacin pharmacokinetics in subjects with normal and impaired renal function. ( Fillastre, JP; Humbert, G; Leroy, A, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kolendo, SE | 1 |
| Vorob'ev, PA | 1 |
| Dvoretskiĭ, LI | 1 |
| Izotova, GN | 1 |
| Miagkov, AV | 1 |
| Shvyreva, GS | 1 |
| Iakovlev, SV | 1 |
| Blum, RA | 1 |
| Fillastre, JP | 2 |
| Leroy, A | 2 |
| Moulin, B | 1 |
| Dhib, M | 1 |
| Borsa-Lebas, F | 1 |
| Humbert, G | 2 |
2 reviews available for lomefloxacin and Chronic Kidney Failure
| Article | Year |
|---|---|
Influence of renal function on the pharmacokinetics of lomefloxacin compared with other fluoroquinolones.
Topics: Anti-Infective Agents; Creatinine; Fluoroquinolones; Humans; Kidney Failure, Chronic; Meta-Analysis | 1992 |
Pharmacokinetics of quinolones in renal insufficiency.
Topics: Anti-Infective Agents; Ciprofloxacin; Enoxacin; Fleroxacin; Fluoroquinolones; Glomerular Filtration | 1990 |
2 other studies available for lomefloxacin and Chronic Kidney Failure
| Article | Year |
|---|---|
[Lomefloxacin pharmacokinetics in patients in the terminal stage of chronic renal insufficiency, undergoing treatment with programmed hemodialysis].
Topics: Anti-Infective Agents; Combined Modality Therapy; Fluoroquinolones; Humans; Kidney Failure, Chronic; | 1995 |
Lomefloxacin pharmacokinetics in subjects with normal and impaired renal function.
Topics: 4-Quinolones; Adult; Anti-Infective Agents; Female; Fluoroquinolones; Half-Life; Humans; Kidney Fail | 1990 |