lomefloxacin has been researched along with Chronic Disease in 11 studies
lomefloxacin: structure given in first source
lomefloxacin : A fluoroquinolone antibiotic, used (generally as the hydrochloride salt) to treat bacterial infections including bronchitis and urinary tract infections. It is also used to prevent urinary tract infections prior to surgery.
Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The efficacy and safety of three oral fluoroquinolones (lomefloxacin, levofloxacin, and ciprofloxacin) for the treatment of chronic osteomyelitis were analyzed." | 9.09 | Ciprofloxacin, lomefloxacin, or levofloxacin as treatment for chronic osteomyelitis. ( Greenberg, RN; Newman, MT; Pectol, RW; Shariaty, S, 2000) |
| "Comparative efficacy of lomefloxacin (400 mg daily for 5 days) and roxithromycin (150 mg daily for 5 days) was studied in the treatment of 24 patients (12 males and 12 females) at the age of 39 to 83 years (the average age of 59 years) with exacerbation of chronic obstructive bronchitis." | 9.08 | [Efficacy of lomefloxacin in treatment of patients with chronic bronchitis]. ( Bykova, AV; Emel'ianov, AV; Fedoseev, GB; Rudinskiĭ, KA; Shevelev, SE, 1998) |
| "Nine centers in Italy participated in a worldwide, multicenter study comparing the effectiveness and safety of lomefloxacin and amoxicillin in patients with acute exacerbations of chronic bronchitis caused mainly by gram-negative pathogens." | 9.07 | Lomefloxacin versus amoxicillin in the treatment of acute exacerbations of chronic bronchitis: an Italian multicenter study. ( Albera, C; Grassi, C; Pozzi, E, 1992) |
| "In two multicenter trials, lomefloxacin and cefaclor were compared as treatments for acute bacterial exacerbations of chronic bronchitis." | 9.07 | Safety and efficacy of lomefloxacin versus cefaclor in the treatment of acute exacerbations of chronic bronchitis. ( Ellison, WT; Gotfried, MH, 1992) |
| "Lomefloxacin has been shown to produce high and sustained concentrations in serum and bronchial mucosa after once-daily administration." | 6.67 | A double-blind study of two dosage regimens of lomefloxacin in bacteriologically proven exacerbations of chronic bronchitis of gram-negative etiology. ( Kemper, P; Köhler, D, 1992) |
| " Compared with the data reported for young adults, the elimination half-life (12." | 5.28 | Steady-state pharmacokinetics and sputum penetration of lomefloxacin in patients with chronic obstructive pulmonary disease and acute respiratory tract infections. ( Glerum, JH; Hoepelman, AI; Kovarik, JM; Rozenberg-Arska, M; Sips, PA; Smit, JM; Verhoef, J, 1992) |
| "The efficacy and safety of three oral fluoroquinolones (lomefloxacin, levofloxacin, and ciprofloxacin) for the treatment of chronic osteomyelitis were analyzed." | 5.09 | Ciprofloxacin, lomefloxacin, or levofloxacin as treatment for chronic osteomyelitis. ( Greenberg, RN; Newman, MT; Pectol, RW; Shariaty, S, 2000) |
| "Comparative efficacy of lomefloxacin (400 mg daily for 5 days) and roxithromycin (150 mg daily for 5 days) was studied in the treatment of 24 patients (12 males and 12 females) at the age of 39 to 83 years (the average age of 59 years) with exacerbation of chronic obstructive bronchitis." | 5.08 | [Efficacy of lomefloxacin in treatment of patients with chronic bronchitis]. ( Bykova, AV; Emel'ianov, AV; Fedoseev, GB; Rudinskiĭ, KA; Shevelev, SE, 1998) |
| "Nine centers in Italy participated in a worldwide, multicenter study comparing the effectiveness and safety of lomefloxacin and amoxicillin in patients with acute exacerbations of chronic bronchitis caused mainly by gram-negative pathogens." | 5.07 | Lomefloxacin versus amoxicillin in the treatment of acute exacerbations of chronic bronchitis: an Italian multicenter study. ( Albera, C; Grassi, C; Pozzi, E, 1992) |
| "In two multicenter trials, lomefloxacin and cefaclor were compared as treatments for acute bacterial exacerbations of chronic bronchitis." | 5.07 | Safety and efficacy of lomefloxacin versus cefaclor in the treatment of acute exacerbations of chronic bronchitis. ( Ellison, WT; Gotfried, MH, 1992) |
| "Lomefloxacin has been shown to produce high and sustained concentrations in serum and bronchial mucosa after once-daily administration." | 2.67 | A double-blind study of two dosage regimens of lomefloxacin in bacteriologically proven exacerbations of chronic bronchitis of gram-negative etiology. ( Kemper, P; Köhler, D, 1992) |
| " Compared with the data reported for young adults, the elimination half-life (12." | 1.28 | Steady-state pharmacokinetics and sputum penetration of lomefloxacin in patients with chronic obstructive pulmonary disease and acute respiratory tract infections. ( Glerum, JH; Hoepelman, AI; Kovarik, JM; Rozenberg-Arska, M; Sips, PA; Smit, JM; Verhoef, J, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (72.73) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Naber, KG | 1 |
| Smelov, V | 1 |
| Perekalina, T | 1 |
| Artemenko, N | 1 |
| Smelova, N | 1 |
| Ukleeva, G | 1 |
| Gorelov, A | 1 |
| Fedoseev, GB | 1 |
| Emel'ianov, AV | 1 |
| Rudinskiĭ, KA | 1 |
| Shevelev, SE | 1 |
| Bykova, AV | 1 |
| Iakovlev, SV | 1 |
| El'kun, GB | 1 |
| Greenberg, RN | 1 |
| Newman, MT | 1 |
| Shariaty, S | 1 |
| Pectol, RW | 1 |
| Belousov, IuB | 1 |
| Efremenkova, OV | 1 |
| Sokolov, AV | 1 |
| Tishenkova, IF | 1 |
| Grassi, C | 1 |
| Albera, C | 1 |
| Pozzi, E | 1 |
| Gotfried, MH | 1 |
| Ellison, WT | 1 |
| Kemper, P | 1 |
| Köhler, D | 1 |
| Kovarik, JM | 1 |
| Hoepelman, AI | 1 |
| Smit, JM | 1 |
| Sips, PA | 1 |
| Rozenberg-Arska, M | 1 |
| Glerum, JH | 1 |
| Verhoef, J | 1 |
9 trials available for lomefloxacin and Chronic Disease
| Article | Year |
|---|---|
Lomefloxacin versus ciprofloxacin in the treatment of chronic bacterial prostatitis.
Topics: Administration, Oral; Adult; Anti-Infective Agents; Chronic Disease; Ciprofloxacin; Fluoroquinolones | 2002 |
[Efficacy of lomefloxacin in treatment of patients with chronic bronchitis].
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents; Bronchitis; Chronic Di | 1998 |
[Pharmacodynamic and pharmacokinetic approaches to optimization of lomefloxacin].
Topics: Age Factors; Aged; Anti-Infective Agents; Bronchitis; Chronic Disease; Escherichia coli; Fluoroquino | 1998 |
[Effectiveness of maxaquin and tarivid in combined therapy of patients with chronic sinusitis].
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Antitubercular Agents; Chronic Disease; Drug Therapy | 1999 |
Ciprofloxacin, lomefloxacin, or levofloxacin as treatment for chronic osteomyelitis.
Topics: Adult; Anti-Infective Agents; Chronic Disease; Ciprofloxacin; Female; Fluoroquinolones; Follow-Up St | 2000 |
[The importance of fluoroquinolones in treating pneumonia in the elderly].
Topics: Aged; Anti-Infective Agents; Bronchitis; Chronic Disease; Dose-Response Relationship, Drug; Fluoroqu | 1999 |
Lomefloxacin versus amoxicillin in the treatment of acute exacerbations of chronic bronchitis: an Italian multicenter study.
Topics: Acute Disease; Aged; Amoxicillin; Anti-Infective Agents; Bronchitis; Chi-Square Distribution; Chroni | 1992 |
Safety and efficacy of lomefloxacin versus cefaclor in the treatment of acute exacerbations of chronic bronchitis.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bronchitis; Cefaclor; Chronic | 1992 |
A double-blind study of two dosage regimens of lomefloxacin in bacteriologically proven exacerbations of chronic bronchitis of gram-negative etiology.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bronchitis; Chi-Square Distribution; Chronic | 1992 |
2 other studies available for lomefloxacin and Chronic Disease
| Article | Year |
|---|---|
Chlamydia trachomatis survival in the presence of two fluoroquinolones (lomefloxacin versus levofloxacin) in patients with chronic prostatitis syndrome.
Topics: Anti-Bacterial Agents; Chlamydia trachomatis; Chronic Disease; Fluoroquinolones; Humans; Levofloxaci | 2005 |
Steady-state pharmacokinetics and sputum penetration of lomefloxacin in patients with chronic obstructive pulmonary disease and acute respiratory tract infections.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Chronic Disease; Female; Fluoroquinolones; Humans; L | 1992 |