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lomefloxacin and Chronic Disease

lomefloxacin has been researched along with Chronic Disease in 11 studies

lomefloxacin: structure given in first source
lomefloxacin : A fluoroquinolone antibiotic, used (generally as the hydrochloride salt) to treat bacterial infections including bronchitis and urinary tract infections. It is also used to prevent urinary tract infections prior to surgery.

Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).

Research Excerpts

ExcerptRelevanceReference
"The efficacy and safety of three oral fluoroquinolones (lomefloxacin, levofloxacin, and ciprofloxacin) for the treatment of chronic osteomyelitis were analyzed."9.09Ciprofloxacin, lomefloxacin, or levofloxacin as treatment for chronic osteomyelitis. ( Greenberg, RN; Newman, MT; Pectol, RW; Shariaty, S, 2000)
"Comparative efficacy of lomefloxacin (400 mg daily for 5 days) and roxithromycin (150 mg daily for 5 days) was studied in the treatment of 24 patients (12 males and 12 females) at the age of 39 to 83 years (the average age of 59 years) with exacerbation of chronic obstructive bronchitis."9.08[Efficacy of lomefloxacin in treatment of patients with chronic bronchitis]. ( Bykova, AV; Emel'ianov, AV; Fedoseev, GB; Rudinskiĭ, KA; Shevelev, SE, 1998)
"Nine centers in Italy participated in a worldwide, multicenter study comparing the effectiveness and safety of lomefloxacin and amoxicillin in patients with acute exacerbations of chronic bronchitis caused mainly by gram-negative pathogens."9.07Lomefloxacin versus amoxicillin in the treatment of acute exacerbations of chronic bronchitis: an Italian multicenter study. ( Albera, C; Grassi, C; Pozzi, E, 1992)
"In two multicenter trials, lomefloxacin and cefaclor were compared as treatments for acute bacterial exacerbations of chronic bronchitis."9.07Safety and efficacy of lomefloxacin versus cefaclor in the treatment of acute exacerbations of chronic bronchitis. ( Ellison, WT; Gotfried, MH, 1992)
"Lomefloxacin has been shown to produce high and sustained concentrations in serum and bronchial mucosa after once-daily administration."6.67A double-blind study of two dosage regimens of lomefloxacin in bacteriologically proven exacerbations of chronic bronchitis of gram-negative etiology. ( Kemper, P; Köhler, D, 1992)
" Compared with the data reported for young adults, the elimination half-life (12."5.28Steady-state pharmacokinetics and sputum penetration of lomefloxacin in patients with chronic obstructive pulmonary disease and acute respiratory tract infections. ( Glerum, JH; Hoepelman, AI; Kovarik, JM; Rozenberg-Arska, M; Sips, PA; Smit, JM; Verhoef, J, 1992)
"The efficacy and safety of three oral fluoroquinolones (lomefloxacin, levofloxacin, and ciprofloxacin) for the treatment of chronic osteomyelitis were analyzed."5.09Ciprofloxacin, lomefloxacin, or levofloxacin as treatment for chronic osteomyelitis. ( Greenberg, RN; Newman, MT; Pectol, RW; Shariaty, S, 2000)
"Comparative efficacy of lomefloxacin (400 mg daily for 5 days) and roxithromycin (150 mg daily for 5 days) was studied in the treatment of 24 patients (12 males and 12 females) at the age of 39 to 83 years (the average age of 59 years) with exacerbation of chronic obstructive bronchitis."5.08[Efficacy of lomefloxacin in treatment of patients with chronic bronchitis]. ( Bykova, AV; Emel'ianov, AV; Fedoseev, GB; Rudinskiĭ, KA; Shevelev, SE, 1998)
"Nine centers in Italy participated in a worldwide, multicenter study comparing the effectiveness and safety of lomefloxacin and amoxicillin in patients with acute exacerbations of chronic bronchitis caused mainly by gram-negative pathogens."5.07Lomefloxacin versus amoxicillin in the treatment of acute exacerbations of chronic bronchitis: an Italian multicenter study. ( Albera, C; Grassi, C; Pozzi, E, 1992)
"In two multicenter trials, lomefloxacin and cefaclor were compared as treatments for acute bacterial exacerbations of chronic bronchitis."5.07Safety and efficacy of lomefloxacin versus cefaclor in the treatment of acute exacerbations of chronic bronchitis. ( Ellison, WT; Gotfried, MH, 1992)
"Lomefloxacin has been shown to produce high and sustained concentrations in serum and bronchial mucosa after once-daily administration."2.67A double-blind study of two dosage regimens of lomefloxacin in bacteriologically proven exacerbations of chronic bronchitis of gram-negative etiology. ( Kemper, P; Köhler, D, 1992)
" Compared with the data reported for young adults, the elimination half-life (12."1.28Steady-state pharmacokinetics and sputum penetration of lomefloxacin in patients with chronic obstructive pulmonary disease and acute respiratory tract infections. ( Glerum, JH; Hoepelman, AI; Kovarik, JM; Rozenberg-Arska, M; Sips, PA; Smit, JM; Verhoef, J, 1992)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (72.73)18.2507
2000's3 (27.27)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Naber, KG1
Smelov, V1
Perekalina, T1
Artemenko, N1
Smelova, N1
Ukleeva, G1
Gorelov, A1
Fedoseev, GB1
Emel'ianov, AV1
Rudinskiĭ, KA1
Shevelev, SE1
Bykova, AV1
Iakovlev, SV1
El'kun, GB1
Greenberg, RN1
Newman, MT1
Shariaty, S1
Pectol, RW1
Belousov, IuB1
Efremenkova, OV1
Sokolov, AV1
Tishenkova, IF1
Grassi, C1
Albera, C1
Pozzi, E1
Gotfried, MH1
Ellison, WT1
Kemper, P1
Köhler, D1
Kovarik, JM1
Hoepelman, AI1
Smit, JM1
Sips, PA1
Rozenberg-Arska, M1
Glerum, JH1
Verhoef, J1

Trials

9 trials available for lomefloxacin and Chronic Disease

ArticleYear
Lomefloxacin versus ciprofloxacin in the treatment of chronic bacterial prostatitis.
    International journal of antimicrobial agents, 2002, Volume: 20, Issue:1

    Topics: Administration, Oral; Adult; Anti-Infective Agents; Chronic Disease; Ciprofloxacin; Fluoroquinolones

2002
[Efficacy of lomefloxacin in treatment of patients with chronic bronchitis].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 1998, Volume: 43, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents; Bronchitis; Chronic Di

1998
[Pharmacodynamic and pharmacokinetic approaches to optimization of lomefloxacin].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 1998, Volume: 43, Issue:10

    Topics: Age Factors; Aged; Anti-Infective Agents; Bronchitis; Chronic Disease; Escherichia coli; Fluoroquino

1998
[Effectiveness of maxaquin and tarivid in combined therapy of patients with chronic sinusitis].
    Vestnik otorinolaringologii, 1999, Issue:6

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Antitubercular Agents; Chronic Disease; Drug Therapy

1999
Ciprofloxacin, lomefloxacin, or levofloxacin as treatment for chronic osteomyelitis.
    Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:1

    Topics: Adult; Anti-Infective Agents; Chronic Disease; Ciprofloxacin; Female; Fluoroquinolones; Follow-Up St

2000
[The importance of fluoroquinolones in treating pneumonia in the elderly].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 1999, Volume: 44, Issue:12

    Topics: Aged; Anti-Infective Agents; Bronchitis; Chronic Disease; Dose-Response Relationship, Drug; Fluoroqu

1999
Lomefloxacin versus amoxicillin in the treatment of acute exacerbations of chronic bronchitis: an Italian multicenter study.
    The American journal of medicine, 1992, Apr-06, Volume: 92, Issue:4A

    Topics: Acute Disease; Aged; Amoxicillin; Anti-Infective Agents; Bronchitis; Chi-Square Distribution; Chroni

1992
Safety and efficacy of lomefloxacin versus cefaclor in the treatment of acute exacerbations of chronic bronchitis.
    The American journal of medicine, 1992, Apr-06, Volume: 92, Issue:4A

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bronchitis; Cefaclor; Chronic

1992
A double-blind study of two dosage regimens of lomefloxacin in bacteriologically proven exacerbations of chronic bronchitis of gram-negative etiology.
    The American journal of medicine, 1992, Apr-06, Volume: 92, Issue:4A

    Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bronchitis; Chi-Square Distribution; Chronic

1992

Other Studies

2 other studies available for lomefloxacin and Chronic Disease

ArticleYear
Chlamydia trachomatis survival in the presence of two fluoroquinolones (lomefloxacin versus levofloxacin) in patients with chronic prostatitis syndrome.
    Andrologia, 2005, Volume: 37, Issue:2-3

    Topics: Anti-Bacterial Agents; Chlamydia trachomatis; Chronic Disease; Fluoroquinolones; Humans; Levofloxaci

2005
Steady-state pharmacokinetics and sputum penetration of lomefloxacin in patients with chronic obstructive pulmonary disease and acute respiratory tract infections.
    Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:11

    Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Chronic Disease; Female; Fluoroquinolones; Humans; L

1992