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lomefloxacin and Bacterial Disease

lomefloxacin has been researched along with Bacterial Disease in 20 studies

lomefloxacin: structure given in first source
lomefloxacin : A fluoroquinolone antibiotic, used (generally as the hydrochloride salt) to treat bacterial infections including bronchitis and urinary tract infections. It is also used to prevent urinary tract infections prior to surgery.

Research Excerpts

ExcerptRelevanceReference
"5% in the lomefloxacin group and from 94% to zero in the chloramphenicol group; rates of hyperemia decreased from 100% to zero in both groups."9.13Postoperative lomefloxacin 0.3% prophylaxis in strabismus surgery. ( Axer-Siegel, R; Bagan, J; Ehrlich, R; Friling, R; Goldenberg-Cohen, N; Hasanreisoglu, M; Snir, M, 2008)
"The clinical efficacy, safety and usefulness of lomefloxacin (LFLX, NY-198), a new quinolone antimicrobial agent, were compared with those of pipemidic acid (PPA) in the treatment of infectious enteritis (bacillary dysentery, enteropathogenic Escherichia coli enteritis and Campylobacter enteritis) by a double blind method."9.06[Comparison of clinical efficacy of lomefloxacin (LFLX, NY-198) and pipemidic acid (PPA) in the treatment of infectious enteritis by a double-blind method. The Japan Research Committee of Lomefloxacin Research Group Enteritis]. ( Aoki, T; Kanehisa, N; Matsubara, Y; Murata, M; Nitta, Y; Sagara, H; Seo, T; Shimizu, N; Takizawa, Y; Tomizawa, I, 1989)
"5% in the lomefloxacin group and from 94% to zero in the chloramphenicol group; rates of hyperemia decreased from 100% to zero in both groups."5.13Postoperative lomefloxacin 0.3% prophylaxis in strabismus surgery. ( Axer-Siegel, R; Bagan, J; Ehrlich, R; Friling, R; Goldenberg-Cohen, N; Hasanreisoglu, M; Snir, M, 2008)
"The clinical efficacy, safety and usefulness of lomefloxacin (LFLX, NY-198), a new quinolone antimicrobial agent, were compared with those of pipemidic acid (PPA) in the treatment of infectious enteritis (bacillary dysentery, enteropathogenic Escherichia coli enteritis and Campylobacter enteritis) by a double blind method."5.06[Comparison of clinical efficacy of lomefloxacin (LFLX, NY-198) and pipemidic acid (PPA) in the treatment of infectious enteritis by a double-blind method. The Japan Research Committee of Lomefloxacin Research Group Enteritis]. ( Aoki, T; Kanehisa, N; Matsubara, Y; Murata, M; Nitta, Y; Sagara, H; Seo, T; Shimizu, N; Takizawa, Y; Tomizawa, I, 1989)
"Results of trials of lomefloxacin (400 mg once daily) in elderly patients with uncomplicated urinary tract infections, complicated urinary tract infections, acute bacterial exacerbations of chronic bronchitis, and as prophylaxis for transurethral surgical procedures (400 mg single dose) have been analyzed."4.78Infection in the elderly: studies with lomefloxacin. ( Bruce-Jones, P; Crome, P, 1992)
"Lomefloxacin is a new fluoroquinolone antimicrobial agent that has undergone extensive worldwide clinical evaluation."2.38The U.S. clinical experience with lomefloxacin, a new once-daily fluoroquinolone. ( Rizk, E, 1992)
"Lomefloxacin is a new oral fluoroquinolone that is indicated for the treatment of various bacterial infections."2.38Lomefloxacin and temafloxacin: two new fluoroquinolone antimicrobials. ( Nix, DE; Symonds, WT, 1992)
" Lomefloxacin offers certain advantages compared with other quinolone antibacterial drugs in that it may be conveniently administered once daily and theophylline dosage adjustment does not appear to be necessary in patients receiving this bronchodilator concomitantly."2.38Lomefloxacin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use. ( Goa, KL; Wadworth, AN, 1991)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19908 (40.00)18.7374
1990's10 (50.00)18.2507
2000's2 (10.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Domagala, JM1
Bridges, AJ1
Culbertson, TP1
Gambino, L1
Hagen, SE1
Karrick, G1
Porter, K1
Sanchez, JP1
Sesnie, JA1
Spense, FG1
Snir, M1
Hasanreisoglu, M1
Friling, R1
Goldenberg-Cohen, N1
Ehrlich, R1
Bagan, J1
Axer-Siegel, R1
Jones, RN1
Rossolini, GM1
Valentini, S1
Vaiani, G2
Satta, G1
Cuffini, AM1
Tullio, V1
Carlone, NA1
Suzuki, T1
Sasada, M1
Okuma, M1
Fukuhara, S1
Yasuda, N1
Amano, H1
Kanachi, K1
Ohno, T1
Kawasaki, T1
Yumoto, Y1
Kim, JH2
Kang, JA1
Kim, YG1
Kim, JW2
Lee, JH2
Choi, EC2
Kim, BK2
Choi, KH1
Padeĭskaia, EN1
Crome, P1
Bruce-Jones, P1
Rizk, E1
Symonds, WT1
Nix, DE1
Soejima, R1
Matsumoto, F1
Wadworth, AN1
Goa, KL1
Aoki, T1
Shimizu, N1
Tomizawa, I1
Takizawa, Y1
Matsubara, Y1
Nitta, Y1
Sagara, H1
Seo, T1
Kanehisa, N1
Murata, M1
Ono, Y1
Kunii, O1
Edwards, R1
Kanematsu, M1
Greenwood, D1
Tanimura, H1
Aoki, Y1
Uesaka, K1
Kasano, Y1
Nakai, T1
Kitamura, T1
Mukaihara, S1
Tamura, K1
Yotsumoto, F1
Terao, R1
Hirose, T1
Okezaki, E1
Kato, H1
Ito, Y1
Inoue, M1
Mitsuhashi, S1

Reviews

6 reviews available for lomefloxacin and Bacterial Disease

ArticleYear
[A broad-spectrum antimicrobial preparation--lomefloxacin (Maxaquin): the results of 10 years of its use in the clinics of Russia].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2000, Volume: 45, Issue:1

    Topics: Anti-Infective Agents; Anti-Infective Agents, Urinary; Antitubercular Agents; Bacterial Infections;

2000
Infection in the elderly: studies with lomefloxacin.
    The American journal of medicine, 1992, Apr-06, Volume: 92, Issue:4A

    Topics: Aged; Aging; Anti-Infective Agents; Bacterial Infections; Bronchitis; Female; Fluoroquinolones; Huma

1992
The U.S. clinical experience with lomefloxacin, a new once-daily fluoroquinolone.
    The American journal of medicine, 1992, Apr-06, Volume: 92, Issue:4A

    Topics: Anti-Infective Agents; Bacterial Infections; Bronchitis; Fluoroquinolones; Humans; Meta-Analysis as

1992
Lomefloxacin and temafloxacin: two new fluoroquinolone antimicrobials.
    Clinical pharmacy, 1992, Volume: 11, Issue:9

    Topics: Anti-Infective Agents; Bacteria; Bacterial Infections; Drug Interactions; Drug Resistance, Microbial

1992
[Review [new antimicrobial agent series XLI]: lomefloxacin].
    The Japanese journal of antibiotics, 1991, Volume: 44, Issue:10

    Topics: Animals; Anti-Infective Agents; Bacteria; Bacterial Infections; Drug Evaluation; Drug Resistance, Mi

1991
Lomefloxacin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.
    Drugs, 1991, Volume: 42, Issue:6

    Topics: Animals; Anti-Infective Agents; Bacteria; Bacterial Infections; Drug Interactions; Fluoroquinolones;

1991

Trials

3 trials available for lomefloxacin and Bacterial Disease

ArticleYear
Postoperative lomefloxacin 0.3% prophylaxis in strabismus surgery.
    Current eye research, 2008, Volume: 33, Issue:10

    Topics: Administration, Topical; Adolescent; Adult; Aged; Anti-Infective Agents; Bacterial Infections; Child

2008
[Clinical efficacy of lomefloxacin for associated infection in patients with hematological diseases].
    Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 1997, Volume: 71, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bacterial Infections; Female; Flu

1997
[Comparison of clinical efficacy of lomefloxacin (LFLX, NY-198) and pipemidic acid (PPA) in the treatment of infectious enteritis by a double-blind method. The Japan Research Committee of Lomefloxacin Research Group Enteritis].
    Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 1989, Volume: 63, Issue:6

    Topics: 4-Quinolones; Adolescent; Adult; Aged; Anti-Infective Agents; Bacterial Infections; Double-Blind Met

1989

Other Studies

11 other studies available for lomefloxacin and Bacterial Disease

ArticleYear
Synthesis and biological activity of 5-amino- and 5-hydroxyquinolones, and the overwhelming influence of the remote N1-substituent in determining the structure-activity relationship.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:3

    Topics: Alkylation; Aminoquinolines; Animals; Anti-Bacterial Agents; Bacterial Infections; Chemical Phenomen

1991
In vitro evaluation of lomefloxacin (NY-198 or SC-47111), a new difluoro-quinolone.
    Journal of chemotherapy (Florence, Italy), 1989, Volume: 1, Issue:4 Suppl

    Topics: Anti-Infective Agents; Bacteria; Bacterial Infections; Fluoroquinolones; Humans; Microbial Sensitivi

1989
In vitro antimicrobial activity of lomefloxacin against staphylococci, enterococci, and Enterobacteriaceae.
    Journal of chemotherapy (Florence, Italy), 1989, Volume: 1, Issue:4 Suppl

    Topics: Anti-Infective Agents; Bacterial Infections; Enterobacteriaceae; Enterococcus; Fluoroquinolones; Hum

1989
Comparison of the antibacterial activity of lomefloxacin with that of other antibiotic/chemotherapeutic agents.
    Journal of chemotherapy (Florence, Italy), 1989, Volume: 1, Issue:4 Suppl

    Topics: Anti-Bacterial Agents; Bacterial Infections; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive

1989
In vitro and in vivo antibacterial efficacies of CFC-222, a new fluoroquinolone.
    Antimicrobial agents and chemotherapy, 1997, Volume: 41, Issue:10

    Topics: Animals; Anti-Infective Agents; Bacteria; Bacterial Infections; Ciprofloxacin; Culture Media; Fluoro

1997
In-vitro and in-vivo antibacterial activity of CFC-222, a new fluoroquinolone.
    The Journal of antimicrobial chemotherapy, 1998, Volume: 41, Issue:2

    Topics: Animals; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Fluoroquinolones; Male; Mice; M

1998
Lomefloxacin reaches U.S. market.
    Clinical pharmacy, 1992, Volume: 11, Issue:6

    Topics: Anti-Infective Agents; Bacterial Infections; Fluoroquinolones; Humans; Quinolones; United States; Un

1992
[Studies of lomefloxacin in biliary tract infections].
    The Japanese journal of antibiotics, 1989, Volume: 42, Issue:4

    Topics: 4-Quinolones; Adult; Aged; Anti-Infective Agents; Bacteria; Bacterial Infections; Biliary Tract Dise

1989
Laboratory assessment of lomefloxacin (SC-47111) in comparison with norfloxacin.
    The Journal of antimicrobial chemotherapy, 1988, Volume: 22, Issue:6

    Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Fluoroquinolones; Humans; Microbial Sensitivi

1988
[Chemotherapy for biliary tract infection (XXXIII). Tissue concentration of NY-198 in gallbladder, biliary excretion and clinical effects].
    Nihon geka hokan. Archiv fur japanische Chirurgie, 1988, Sep-01, Volume: 57, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bacterial Infections; Bile; Cholangitis; Chol

1988
In vitro and in vivo activity of NY-198, a new difluorinated quinolone.
    Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:6

    Topics: Animals; Anti-Infective Agents; Bacterial Infections; Fluoroquinolones; Male; Mice; Microbial Sensit

1987