Page last updated: 2024-10-30

lomefloxacin and Acute Confusional Senile Dementia

lomefloxacin has been researched along with Acute Confusional Senile Dementia in 30 studies

lomefloxacin: structure given in first source
lomefloxacin : A fluoroquinolone antibiotic, used (generally as the hydrochloride salt) to treat bacterial infections including bronchitis and urinary tract infections. It is also used to prevent urinary tract infections prior to surgery.

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (10.00)29.6817
2010's22 (73.33)24.3611
2020's5 (16.67)2.80

Authors

AuthorsStudies
Marco-Contelles, J1
León, R3
de los Ríos, C1
Samadi, A1
Bartolini, M3
Andrisano, V3
Huertas, O2
Barril, X1
Luque, FJ3
Rodríguez-Franco, MI5
López, B3
López, MG4
García, AG3
Carreiras, Mdo C1
Villarroya, M4
Camps, P1
Formosa, X1
Galdeano, C1
Muñoz-Torrero, D3
Ramírez, L1
Gómez, E1
Isambert, N1
Lavilla, R2
Badia, A1
Clos, MV2
Mancini, F1
Arce, MP4
Dafni, T1
González-Muñoz, GC2
Pérez, C3
Conde, S3
Romero, A1
del Barrio, L1
Martín-de-Saavedra, MD1
Egea, J2
Sun, Y2
Chen, J1
Chen, X1
Huang, L3
Li, X4
Di Pietro, O1
Pérez-Areales, FJ2
Juárez-Jiménez, J1
Espargaró, A2
Pérez, B3
Sabaté, R2
Miao, H1
Meng, F1
Huang, M1
Xie, SS5
Jiang, N4
Lan, JS4
Kong, LY7
Wang, XB6
Dong, G1
Li, ZR1
Wang, KD1
Guo, PP1
Wang, X2
Wang, ZM1
Li, F3
Wu, JJ3
Wang, J3
Pan, W1
Hu, K1
Bai, P1
Yu, L1
Ma, Q1
Li, T1
Zhang, X1
Chen, C1
Peng, K1
Liu, W4
Sang, Z1
Xia, CL1
Wang, N1
Guo, QL1
Liu, ZQ1
Wu, JQ1
Huang, SL1
Ou, TM1
Tan, JH1
Wang, HG1
Li, D1
Huang, ZS1
Monjas, L1
Gil, C1
Zhang, T1
Liu, Y1
Yang, J1
Liu, J2
Miao, ZY1
Ding, Y1
Yang, XL4
Cai, P4
Liu, QH4
Yang, HL3
Fang, SQ1
Tang, YW2
Wang, C2
Xu, YX1
Wang, H2
Li, XK1
Dong, SN1
Liu, WW1
Gong, Q2
Wang, TD1
Tang, Y1
Zhu, J2
Li, J2
Zhang, HY1
Mao, F2
Huang, Q1
Liang, N1
Li, Q3
Kumar, D1
Gupta, SK1
Ganeshpurkar, A1
Gutti, G1
Krishnamurthy, S1
Modi, G1
Singh, SK1
Xu, Y1
Zhang, J1
Wang, W1
Qiu, X1
Zhang, H1
Shi, CJ1
Hu, J1
Pan, T1
An, B1
Li, Z1
Srivastava, P1
Tripathi, PN1
Sharma, P1
Shrivastava, SK1
Turcu, AL2
Barniol-Xicota, M1
Pont, C1
Pivetta, D1
De Simone, A1
Sureda, FX2
Vázquez, S2
Jiang, X2
Zhou, J1
Wang, Y4
Chen, L2
Duan, Y1
Huang, J1
Liu, C2
Chen, Y2
Sun, H2
Feng, F2
Qu, W1
Xing, C1
Lyu, W1
Wang, S1
Chen, T1
Qu, L1
Ji, L1
Luo, H1
Li, S1
Peng, W1
Yin, F1
Lu, D1
Liu, X1
Kong, L1
Sun, X1
Lei, Z1
Yue, S1
Sun, J1
Companys-Alemany, J1
Phillips, MB1
Patel, DS1
Griñán-Ferré, C1
Loza, MI1
Brea, JM1
Soto, D1
Kurnikova, MG1
Johnson, JW1
Pallàs, M1

Other Studies

30 other studies available for lomefloxacin and Acute Confusional Senile Dementia

ArticleYear
Tacripyrines, the first tacrine-dihydropyridine hybrids, as multitarget-directed ligands for the treatment of Alzheimer's disease.
    Journal of medicinal chemistry, 2009, May-14, Volume: 52, Issue:9

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Blood-Brain Barrier; Butyrylcholines

2009
Pyrano[3,2-c]quinoline-6-chlorotacrine hybrids as a novel family of acetylcholinesterase- and beta-amyloid-directed anti-Alzheimer compounds.
    Journal of medicinal chemistry, 2009, Sep-10, Volume: 52, Issue:17

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases

2009
Neuroprotective and cholinergic properties of multifunctional glutamic acid derivatives for the treatment of Alzheimer's disease.
    Journal of medicinal chemistry, 2009, Nov-26, Volume: 52, Issue:22

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Cataly

2009
N-acylaminophenothiazines: neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:6

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Antineoplastic Agents; Butyrylcholinesterase; Calcium; Cel

2011
Inhibition of cholinesterase and monoamine oxidase-B activity by Tacrine-Homoisoflavonoid hybrids.
    Bioorganic & medicinal chemistry, 2013, Dec-01, Volume: 21, Issue:23

    Topics: Alzheimer Disease; Animals; Blood-Brain Barrier; Cholinesterase Inhibitors; Cholinesterases; Electro

2013
Tetrahydrobenzo[h][1,6]naphthyridine-6-chlorotacrine hybrids as a new family of anti-Alzheimer agents targeting β-amyloid, tau, and cholinesterase pathologies.
    European journal of medicinal chemistry, 2014, Sep-12, Volume: 84

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Cholinesterase Inhibitors; Cholinesterases; Dose-Response

2014
Discovery of indanone derivatives as multi-target-directed ligands against Alzheimer's disease.
    European journal of medicinal chemistry, 2014, Nov-24, Volume: 87

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Blood-Brain Barrier; B

2014
Multifunctional coumarin derivatives: monoamine oxidase B (MAO-B) inhibition, anti-β-amyloid (Aβ) aggregation and metal chelation properties against Alzheimer's disease.
    Bioorganic & medicinal chemistry letters, 2015, Feb-01, Volume: 25, Issue:3

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Binding Sites; Blood-Brain Barrier; Cell Line, Tu

2015
Multifunctional tacrine-trolox hybrids for the treatment of Alzheimer's disease with cholinergic, antioxidant, neuroprotective and hepatoprotective properties.
    European journal of medicinal chemistry, 2015, Mar-26, Volume: 93

    Topics: Alzheimer Disease; Animals; Antioxidants; Biphenyl Compounds; Blood-Brain Barrier; Cell Survival; Ch

2015
Design, synthesis and biological evaluation of novel donepezil-coumarin hybrids as multi-target agents for the treatment of Alzheimer's disease.
    Bioorganic & medicinal chemistry, 2016, Apr-01, Volume: 24, Issue:7

    Topics: Alzheimer Disease; Animals; Butyrylcholinesterase; Cell Line, Tumor; Cholinesterase Inhibitors; Chol

2016
Design, synthesis and evaluation of novel ferulic acid-memoquin hybrids as potential multifunctional agents for the treatment of Alzheimer's disease.
    Bioorganic & medicinal chemistry letters, 2016, 05-15, Volume: 26, Issue:10

    Topics: Alkanes; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Blood-Brain Barrier; Chemi

2016
Design, synthesis and evaluation of 2-arylethenyl-N-methylquinolinium derivatives as effective multifunctional agents for Alzheimer's disease treatment.
    European journal of medicinal chemistry, 2017, Apr-21, Volume: 130

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Blood-Brain Barrier; Cell Death; Cell Line;

2017
Enzymatic and solid-phase synthesis of new donepezil-based L- and d-glutamic acid derivatives and their pharmacological evaluation in models related to Alzheimer's disease and cerebral ischemia.
    European journal of medicinal chemistry, 2017, Apr-21, Volume: 130

    Topics: Alzheimer Disease; Animals; Brain Ischemia; Calcium Channel Blockers; Cholinesterase Inhibitors; Don

2017
Design, synthesis and biological activity of novel donepezil derivatives bearing N-benzyl pyridinium moiety as potent and dual binding site acetylcholinesterase inhibitors.
    European journal of medicinal chemistry, 2017, Jun-16, Volume: 133

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Cell S

2017
Synthesis and pharmacological evaluation of novel chromone derivatives as balanced multifunctional agents against Alzheimer's disease.
    Bioorganic & medicinal chemistry, 2017, 07-15, Volume: 25, Issue:14

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Apoptosis; Binding Sites; Blood-Bra

2017
Design, synthesis and evaluation of coumarin-pargyline hybrids as novel dual inhibitors of monoamine oxidases and amyloid-β aggregation for the treatment of Alzheimer's disease.
    European journal of medicinal chemistry, 2017, Sep-29, Volume: 138

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Survival; Coumarins; Dose-Response Relations

2017
Design, synthesis, and evaluation of salicyladimine derivatives as multitarget-directed ligands against Alzheimer's disease.
    Bioorganic & medicinal chemistry, 2017, 11-01, Volume: 25, Issue:21

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Survival; Dose-Response Relationship, Drug;

2017
Discovery of novel propargylamine-modified 4-aminoalkyl imidazole substituted pyrimidinylthiourea derivatives as multifunctional agents for the treatment of Alzheimer's disease.
    European journal of medicinal chemistry, 2018, Jan-01, Volume: 143

    Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Butyrylcholinesterase; Cholinesterase Inhibitors;

2018
Design, synthesis and biological evaluation of new coumarin-dithiocarbamate hybrids as multifunctional agents for the treatment of Alzheimer's disease.
    European journal of medicinal chemistry, 2018, Feb-25, Volume: 146

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Cell L

2018
Development of Piperazinediones as dual inhibitor for treatment of Alzheimer's disease.
    European journal of medicinal chemistry, 2018, Apr-25, Volume: 150

    Topics: Acetylcholinesterase; Alzheimer Disease; Butyrylcholinesterase; Diketopiperazines; Dose-Response Rel

2018
Design, synthesis and evaluation of vilazodone-tacrine hybrids as multitarget-directed ligands against depression with cognitive impairment.
    Bioorganic & medicinal chemistry, 2018, 07-23, Volume: 26, Issue:12

    Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Blood-Brain Barrier; Butyrylcholinesterase; Cholin

2018
Synthesis and evaluation of isoprenylation-resveratrol dimer derivatives against Alzheimer's disease.
    European journal of medicinal chemistry, 2019, Feb-01, Volume: 163

    Topics: Alzheimer Disease; Animals; Antioxidants; Blood-Brain Barrier; Cell Line; Dimerization; Humans; Mice

2019
Synthesis and evaluation of clioquinol-rolipram/roflumilast hybrids as multitarget-directed ligands for the treatment of Alzheimer's disease.
    European journal of medicinal chemistry, 2019, Feb-01, Volume: 163

    Topics: Alzheimer Disease; Aminopyridines; Animals; Benzamides; Clioquinol; Cyclic Nucleotide Phosphodiester

2019
Design, synthesis, and evaluation of novel N-(4-phenoxybenzyl)aniline derivatives targeting acetylcholinesterase, β-amyloid aggregation and oxidative stress to treat Alzheimer's disease.
    Bioorganic & medicinal chemistry, 2019, 08-15, Volume: 27, Issue:16

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Drug Design; Humans; Oxidative Stres

2019
A novel class of multitarget anti-Alzheimer benzohomoadamantane‒chlorotacrine hybrids modulating cholinesterases and glutamate NMDA receptors.
    European journal of medicinal chemistry, 2019, Oct-15, Volume: 180

    Topics: Acetylcholinesterase; Adamantane; Alzheimer Disease; Butyrylcholinesterase; Cholinesterase Inhibitor

2019
Rational design and biological evaluation of a new class of thiazolopyridyl tetrahydroacridines as cholinesterase and GSK-3 dual inhibitors for Alzheimer's disease.
    European journal of medicinal chemistry, 2020, Dec-01, Volume: 207

    Topics: Acetylcholinesterase; Acridines; Alzheimer Disease; Animals; Blood-Brain Barrier; Cholinesterase Inh

2020
Discovery of potent glycogen synthase kinase 3/cholinesterase inhibitors with neuroprotection as potential therapeutic agent for Alzheimer's disease.
    Bioorganic & medicinal chemistry, 2021, 01-15, Volume: 30

    Topics: Acetylcholinesterase; Alzheimer Disease; Cholinesterase Inhibitors; Dose-Response Relationship, Drug

2021
Synthesis and evaluation of multi-target-directed ligands with BACE-1 inhibitory and Nrf2 agonist activities as potential agents against Alzheimer's disease.
    European journal of medicinal chemistry, 2021, Jul-05, Volume: 219

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Antioxidants; Aspart

2021
Development of 5-hydroxyl-1-azabenzanthrone derivatives as dual binding site and selective acetylcholinesterase inhibitors.
    European journal of medicinal chemistry, 2022, Apr-15, Volume: 234

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Binding Sites

2022
Design, synthesis, and in vitro and in vivo characterization of new memantine analogs for Alzheimer's disease.
    European journal of medicinal chemistry, 2022, Jun-05, Volume: 236

    Topics: Alzheimer Disease; Animals; Caenorhabditis elegans; Disease Models, Animal; Memantine; Mice; Recepto

2022