Page last updated: 2024-08-26

loganin and Disease Models, Animal

loganin has been researched along with Disease Models, Animal in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (8.33)29.6817
2010's3 (25.00)24.3611
2020's8 (66.67)2.80

Authors

AuthorsStudies
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV1
He, K; Li, S; Liu, J; Nie, L; Xiao, S; Xie, F; Xu, J; Yang, C; Yang, X; Zhang, K; Zhou, L; Zou, L1
Guo, YX; Han, Y; He, J; Shi, R; Wang, YM; Wang, ZX; Xia, CY; Xu, JK; Yan, Y; Zhang, WK1
Duan, Y; Gong, M; Li, B; Long, B; Qin, L; Song, L; Wang, J; Wang, Y; Wu, X; Zhang, Y1
Chen, D; Chen, Q; Du, W; Fu, F; Hu, J; Jin, H; Ruan, H; Tong, P; Wu, C; Wu, J; Yao, S; Yu, H; Zhou, J1
Cheng, W; Hu, T; Li, X; Ma, Q; Song, G; Yuan, J; Zhang, B; Zhang, G1
Guo, KW; Li, L; Luo, Y; Yang, CC; Zhang, L; Zheng, CC1
Cho, YY; Choi, N; Jang, JH; Kang, HC; Lee, HS; Lee, JY; Yang, G1
Lee, MK; Liu, B; Liu, K; Lu, C; Lv, G; Lv, X; Wu, Y; Xu, H1
Feng, H; Li, Y; Li, Z; Shen, B; Shi, L; Tian, Y; Zhao, C1
Chang, FR; Chen, CS; Jong, YJ; Lo, YC; Tseng, YT1
Jang, YP; Kim, SH; Kim, YC; Lee, KY; Oh, TH; Sung, SH1

Other Studies

12 other study(ies) available for loganin and Disease Models, Animal

ArticleYear
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

2020
Loganin substantially ameliorates molecular deficits, pathologies and cognitive impairment in a mouse model of Alzheimer's disease.
    Aging, 2021, 10-23, Volume: 13, Issue:20

    Topics: Alzheimer Disease; Animals; Cognitive Dysfunction; Disease Models, Animal; Female; Hippocampus; Iridoids; Mice; Mice, Transgenic; Morris Water Maze Test; Neuroprotective Agents; Proteome

2021
Loganin improves chronic unpredictable mild stress-induced depressive-like behaviors and neurochemical dysfunction.
    Journal of ethnopharmacology, 2023, May-23, Volume: 308

    Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Depression; Disease Models, Animal; Hippocampus; Mice; Mice, Inbred ICR; Stress, Psychological; Sucrose

2023
Role of BDNF-TrkB signaling in the antidepressant-like actions of loganin, the main active compound of Corni Fructus.
    CNS neuroscience & therapeutics, 2023, Volume: 29, Issue:12

    Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Cornus; Depression; Disease Models, Animal; Hippocampus; Neuroinflammatory Diseases; Receptor, trkB; Stress, Psychological

2023
Loganin ameliorates cartilage degeneration and osteoarthritis development in an osteoarthritis mouse model through inhibition of NF-κB activity and pyroptosis in chondrocytes.
    Journal of ethnopharmacology, 2020, Jan-30, Volume: 247

    Topics: Animals; Chondrocytes; Collagen Type II; Collagen Type X; Cornus; Disease Models, Animal; Fruit; Humans; Iridoids; Male; Menisci, Tibial; Mice; NF-kappa B; Osteoarthritis, Knee; Pyroptosis; Signal Transduction

2020
Protective effects of iridoid glycosides on acute colitis via inhibition of the inflammatory response mediated by the STAT3/NF-кB pathway.
    International immunopharmacology, 2020, Volume: 81

    Topics: Animals; Anti-Inflammatory Agents; Cell Line; Colitis; Colitis, Ulcerative; Cornus; Dextran Sulfate; Disease Models, Animal; Glycosides; Humans; Iridoid Glycosides; Iridoids; Male; Medicine, Chinese Traditional; Mice; Mice, Inbred C57BL; NF-kappa B; Phosphorylation; Signal Transduction; STAT3 Transcription Factor

2020
Cornel Iridoid Glycoside Regulates Modification of Tau and Alleviates Synaptic Abnormalities in Aged P301S Mice.
    Current medical science, 2020, Volume: 40, Issue:6

    Topics: Administration, Oral; Animals; Brain; Cell-Free System; Disease Models, Animal; Female; Glycosides; Humans; Iridoids; Male; Mice; Mice, Transgenic; Models, Molecular; Molecular Docking Simulation; Mutation; Phenotype; Protein Binding; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; tau Proteins; Tauopathies; Treatment Outcome

2020
Loganin Alleviates Gout Inflammation by Suppressing NLRP3 Inflammasome Activation and Mitochondrial Damage.
    Molecules (Basel, Switzerland), 2021, Feb-18, Volume: 26, Issue:4

    Topics: Administration, Oral; Animals; Cells, Cultured; Disease Models, Animal; DNA, Mitochondrial; Gout; Inflammasomes; Inflammation; Iridoids; Macrophages; Male; Mice, Inbred C57BL; Mitochondria; NLR Family, Pyrin Domain-Containing 3 Protein; Uric Acid

2021
Loganin attenuates diabetic nephropathy in C57BL/6J mice with diabetes induced by streptozotocin and fed with diets containing high level of advanced glycation end products.
    Life sciences, 2015, Feb-15, Volume: 123

    Topics: Analysis of Variance; Animals; Blood Urea Nitrogen; Blotting, Western; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; DNA Primers; Dose-Response Relationship, Drug; Gene Expression Regulation; Glycation End Products, Advanced; Iridoids; Kidney; Malondialdehyde; Mice; Mice, Inbred C57BL; Microscopy, Electron, Transmission; Molecular Structure; Oxidative Stress; Pancreas; Proteinuria; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Reverse Transcriptase Polymerase Chain Reaction; Superoxide Dismutase

2015
Loganin inhibits the inflammatory response in mouse 3T3L1 adipocytes and mouse model.
    International immunopharmacology, 2016, Volume: 36

    Topics: 3T3 Cells; Adipocytes; Animals; Anti-Inflammatory Agents; Atherosclerosis; Chemokine CCL2; Disease Models, Animal; Humans; Inflammation; Interleukin-6; Iridoids; Lipid Metabolism; Mice; NF-kappa B; Phosphorylation; Polyethylene Glycols; Signal Transduction; Tumor Necrosis Factor-alpha

2016
Loganin possesses neuroprotective properties, restores SMN protein and activates protein synthesis positive regulator Akt/mTOR in experimental models of spinal muscular atrophy.
    Pharmacological research, 2016, Volume: 111

    Topics: Animals; Apoptosis; Cell Line; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Fibroblasts; Genetic Predisposition to Disease; Humans; Insulin-Like Growth Factor I; Iridoids; Mice; Mice, Transgenic; Motor Activity; Motor Neurons; Muscle Proteins; Muscle Strength; Muscle, Skeletal; Muscular Atrophy, Spinal; Mutation; Nerve Degeneration; Neuroprotective Agents; Phenotype; Phosphorylation; Protein Biosynthesis; Proto-Oncogene Proteins c-akt; RNA Interference; Signal Transduction; SKP Cullin F-Box Protein Ligases; Survival of Motor Neuron 1 Protein; Time Factors; TOR Serine-Threonine Kinases; Transfection; Tripartite Motif Proteins; Ubiquitin-Protein Ligases; Weight Gain

2016
Cognitive-enhancing activity of loganin isolated from Cornus officinalis in scopolamine-induced amnesic mice.
    Archives of pharmacal research, 2009, Volume: 32, Issue:5

    Topics: Acetylcholinesterase; Administration, Oral; Amnesia; Animals; Avoidance Learning; Behavior, Animal; Cholinesterase Inhibitors; Cognition; Cornus; Disease Models, Animal; Dose-Response Relationship, Drug; Fruit; Hippocampus; Iridoids; Male; Memory, Short-Term; Mice; Mice, Inbred ICR; Nootropic Agents; Scopolamine; Time Factors

2009