Page last updated: 2024-08-23

lofexidine and Opioid-Related Disorders

lofexidine has been researched along with Opioid-Related Disorders in 52 studies

Research

Studies (52)

Timeframe	Studies, this research(%)	All Research%
pre-1990	7 (13.46)	18.7374
1990's	8 (15.38)	18.2507
2000's	15 (28.85)	29.6817
2010's	20 (38.46)	24.3611
2020's	2 (3.85)	2.80

Authors

Authors	Studies
Fogelman, N; Hermes, G; Hyman, SM; Kosten, TR; Sinha, R	1
Berger, AA; Hasoon, J; Jung, JW; Kassem, H; Kaye, AD; Mousa, M; Patel, A; Urits, I; Virgen, CG; Viswanath, O; Zusman, R	1
Caliendo, T; Hilas, O	1
Biswas, K; Gorodetzky, CW; Gullo, KL; Martin, PR; Saxon, AJ; Walsh, SL	1
Ali, R; Gowing, L; White, JM	2
Coulton, S; Diaper, AM; Law, FD; Melichar, JK; Myles, JS; Nutt, DJ	1
Assam, PN; Chan, E; Cheok, C; de Souza, NN; Guo, S; Kandasami, G; Koh, PK; Lee, KM; Manning, V; Pangjaya, J; Sultana, R; Wijesinghe, R; Wong, KE; Yang, Y	1
Traynor, K	1
Brooks, T; Doughty, B; Morgenson, D	1
Bryce, C	1
Vartak, AP	1
Clinch, T; Gorodetzky, CW; Gullo, K; Mannix, S; Reinders, S; Vernon, MK	1
Ali, R; Farrell, M; Gowing, L; White, JM	1
Ali, R; Gowing, L; Mbewe, D; White, JM	1
Akerele, E; Al-Ghananeem, AM; Elkashef, A; Fischman, MW; Herman, BH; Kleber, H; Ling, W; Miotto, K; O'Brien, CP; Yu, E	1
Eid, NC; Epstein, DH; Krantz, MJ; Preston, KL; Schmittner, J; Schroeder, JR	1
Abbassi, M; Al Ghananeem, AM; Herman, BH; Ling, W; Miotto, K; Montgomery, A; O'Brien, CP; Walsh, R; Yu, E	1
Gish, EC; Honey, BL; Johnson, PN; Miller, JL	1
Meader, N	1
Bramness, J; Gossop, M; Lobmaier, P; Waal, H	1
Day, E; Strang, J	1
Law, F; Melichar, J; O'Shea, J; Praveen, KT	1
Bearn, J; de Wet, CJ; Glasper, A; Gossop, M; Reed, LJ	1
Banbery, J; Brearley, R; Finnegan, O; Raistrick, D; Thistlethwaite, G; West, D	1
Ali, R; Gowing, L; White, J	1
Cubells, JF; Tang, YL; Zhao, C; Zhao, D	1
Bearn, J; Best, D; Beswick, T; Gossop, M; McCambridge, J; Rees, S; Strang, J	1
Doebrick, C; Kimmerling, A; Kosten, TR; Sinha, R	1
Geyer, G; Resnick, RB; Washton, AM	1
Dackis, CA; Gold, MS; Washton, AM	1
Resnick, RB; Washton, AM	1
Garwood, J; Perzel, JF; Resnick, RB; Washton, AM	1
Annitto, WJ; Extein, I; Gold, MS; Pottash, AC; Sweeney, DR	1
Stewart, AM; Wylie, AS	1
Alcorn, R; Cox, S	1
Beckford, H; Kahn, A; Mumford, JP; Rogers, GA	1
Brown, AS; Fleming, PM	1
Bearn, J; Gossop, M; Strang, J	2
Carnwath, T; Hardman, J	1
Akhurst, JS	1
Bearn, J; Buntwal, N; Gossop, M; Strang, J	1
Delsignore, R; Di Gennaro, C; Gardini, S; Gerra, G; Giusti, F; Zaimovic, A; Zambelli, U	1
Alcorn, R; Feinmann, C; White, R	1
Ali, RL; Farrell, M; Gowing, LR; White, JM	1
Allen, S; Farrell, M; Gupta, J; Howells, C; Marsden, J; Stillwell, G	1
Cook, CC; Lipsedge, MS; Scannell, TD	1

Reviews

16 review(s) available for lofexidine and Opioid-Related Disorders

Article	Year
A Comprehensive Update of Lofexidine for the Management of Opioid Withdrawal Symptoms. Psychopharmacology bulletin, 2020, 07-23, Volume: 50, Issue:3 Topics: Analgesics, Opioid; Clonidine; Humans; Opioid-Related Disorders; Substance Withdrawal Syndrome	2020
Lofexidine: A Novel Treatment Option for Opioid Withdrawal Symptoms. The Senior care pharmacist, 2020, Oct-01, Volume: 35, Issue:10 Topics: Analgesics, Opioid; Clonidine; Humans; Opioid-Related Disorders; United States	2020
Opioid antagonists with minimal sedation for opioid withdrawal. The Cochrane database of systematic reviews, 2017, 05-29, Volume: 5 Topics: Adrenergic alpha-Agonists; Clonidine; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Non-Randomized Controlled Trials as Topic; Opioid-Related Disorders; Prospective Studies; Randomized Controlled Trials as Topic; Severity of Illness Index; Substance Withdrawal Syndrome	2017
Lofexidine: A Newly FDA-Approved, Nonopioid Treatment for Opioid Withdrawal. The Annals of pharmacotherapy, 2019, Volume: 53, Issue:7 Topics: Adult; Clonidine; Humans; Narcotic Antagonists; Opioid-Related Disorders; Randomized Controlled Trials as Topic; Substance Withdrawal Syndrome; United States; United States Food and Drug Administration	2019
Alpha₂-adrenergic agonists for the management of opioid withdrawal. The Cochrane database of systematic reviews, 2016, May-03, Issue:5 Topics: Acute Disease; Adrenergic alpha-2 Receptor Agonists; Clonidine; Controlled Clinical Trials as Topic; Humans; Methadone; Opiate Substitution Treatment; Opioid-Related Disorders; Randomized Controlled Trials as Topic; Substance Withdrawal Syndrome	2016
Buprenorphine for managing opioid withdrawal. The Cochrane database of systematic reviews, 2017, 02-21, Volume: 2 Topics: Acute Disease; Buprenorphine; Clonidine; Female; Humans; Male; Methadone; Narcotic Antagonists; Opiate Substitution Treatment; Opioid-Related Disorders; Randomized Controlled Trials as Topic; Substance Withdrawal Syndrome	2017
Buprenorphine for the management of opioid withdrawal. The Cochrane database of systematic reviews, 2009, Jul-08, Issue:3 Topics: Acute Disease; Buprenorphine; Clonidine; Humans; Narcotic Antagonists; Opioid-Related Disorders; Randomized Controlled Trials as Topic; Substance Withdrawal Syndrome	2009
Lofexidine, an {alpha}2-receptor agonist for opioid detoxification. The Annals of pharmacotherapy, 2010, Volume: 44, Issue:2 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Clinical Trials as Topic; Clonidine; Humans; Narcotic Antagonists; Opioid-Related Disorders; Substance Withdrawal Syndrome	2010
A comparison of methadone, buprenorphine and alpha(2) adrenergic agonists for opioid detoxification: a mixed treatment comparison meta-analysis. Drug and alcohol dependence, 2010, Apr-01, Volume: 108, Issue:1-2 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Buprenorphine; Clonidine; Data Interpretation, Statistical; Humans; Methadone; Narcotic Antagonists; Narcotics; Odds Ratio; Opioid-Related Disorders; Randomized Controlled Trials as Topic; Treatment Outcome	2010
The pharmacological treatment of opioid addiction--a clinical perspective. European journal of clinical pharmacology, 2010, Volume: 66, Issue:6 Topics: Adrenergic Agonists; Analgesics, Opioid; Buprenorphine; Clonidine; Drug Therapy, Combination; Humans; Inactivation, Metabolic; Methadone; Naloxone; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Social Support; Substance Withdrawal Syndrome	2010
Opioid antagonists with minimal sedation for opioid withdrawal. The Cochrane database of systematic reviews, 2006, Jan-25, Issue:1 Topics: Adrenergic alpha-Agonists; Clinical Trials as Topic; Clonidine; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Randomized Controlled Trials as Topic	2006
Opiate addiction in China: current situation and treatments. Addiction (Abingdon, England), 2006, Volume: 101, Issue:5 Topics: Buprenorphine; China; Clonidine; Drugs, Chinese Herbal; HIV Infections; Humans; Methadone; Naltrexone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Substance Abuse, Intravenous; Substance Withdrawal Syndrome; Sympatholytics	2006
The sequential use of clonidine and naltrexone in the treatment of opiate addicts. Advances in alcohol & substance abuse, 1984,Spring, Volume: 3, Issue:3 Topics: Adult; Baclofen; Clonidine; Drug Therapy, Combination; Electric Stimulation Therapy; Endorphins; Ethanol; Female; Humans; Locus Coeruleus; Male; Methyldopa; Naloxone; Naltrexone; Opioid-Related Disorders; Substance Withdrawal Syndrome	1984
Lofexidine and opioid withdrawal. Lancet (London, England), 1995, Jun-03, Volume: 345, Issue:8962 Topics: Antihypertensive Agents; Clonidine; Humans; Opioid-Related Disorders; Substance Withdrawal Syndrome	1995
Lofexidine for opiate detoxification: review of recent randomised and open controlled trials. The American journal on addictions, 1999,Fall, Volume: 8, Issue:4 Topics: Clonidine; Humans; Methadone; Narcotic Antagonists; Opioid-Related Disorders; Randomized Controlled Trials as Topic; Treatment Outcome	1999
Alpha2-adrenergic agonists in opioid withdrawal. Addiction (Abingdon, England), 2002, Volume: 97, Issue:1 Topics: Adrenergic alpha-Agonists; Clonidine; Confidence Intervals; Controlled Clinical Trials as Topic; Humans; Methadone; Narcotics; Odds Ratio; Opioid-Related Disorders; Substance Withdrawal Syndrome; Treatment Outcome	2002

Trials

18 trial(s) available for lofexidine and Opioid-Related Disorders

Article	Year
Lofexidine in Combination With Oral Naltrexone for Opioid Use Disorder Relapse Prevention: A Pilot Randomized, Double-Blind, Placebo-Controlled Study. The American journal on addictions, 2019, Volume: 28, Issue:6 Topics: Administration, Oral; Adolescent; Adult; Chemoprevention; Clonidine; Craving; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Intention to Treat Analysis; Male; Medication Adherence; Middle Aged; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Patient Compliance; Pilot Projects; Recurrence; Secondary Prevention; Substance Withdrawal Syndrome; Treatment Outcome; Young Adult	2019
A phase III, randomized, multi-center, double blind, placebo controlled study of safety and efficacy of lofexidine for relief of symptoms in individuals undergoing inpatient opioid withdrawal. Drug and alcohol dependence, 2017, 07-01, Volume: 176 Topics: Adult; Analgesics, Opioid; Animals; Clonidine; Double-Blind Method; Female; Humans; Inpatients; Male; Middle Aged; Narcotic Antagonists; Opioid-Related Disorders; Substance Withdrawal Syndrome; United Kingdom	2017
Buprenorphine/naloxone versus methadone and lofexidine in community stabilisation and detoxification: A randomised controlled trial of low dose short-term opiate-dependent individuals. Journal of psychopharmacology (Oxford, England), 2017, Volume: 31, Issue:8 Topics: Analgesics, Opioid; Buprenorphine, Naloxone Drug Combination; Clonidine; Craving; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Methadone; Narcotic Antagonists; Opioid-Related Disorders; Substance Withdrawal Syndrome; Treatment Outcome; Young Adult	2017
Lofexidine versus diazepam for the treatment of opioid withdrawal syndrome: A double-blind randomized clinical trial in Singapore. Journal of substance abuse treatment, 2018, Volume: 91 Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Clonidine; Craving; Diazepam; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Opioid-Related Disorders; Pupil; Singapore; Substance Withdrawal Syndrome	2018
Clinical pharmacokinetics of lofexidine, the alpha 2-adrenergic receptor agonist, in opiate addicts plasma using a highly sensitive liquid chromatography tandem mass spectrometric analysis. The American journal of drug and alcohol abuse, 2008, Volume: 34, Issue:5 Topics: Administration, Oral; Adrenergic alpha-Agonists; Adult; Biological Availability; Chromatography, Liquid; Clonidine; Double-Blind Method; Humans; Opioid-Related Disorders; Tandem Mass Spectrometry; Young Adult	2008
Electrocardiographic effects of lofexidine and methadone coadministration: secondary findings from a safety study. Pharmacotherapy, 2009, Volume: 29, Issue:5 Topics: Adult; Clonidine; Drug Administration Schedule; Drug Therapy, Combination; Electrocardiography; Female; Humans; Male; Methadone; Narcotic Antagonists; Opioid-Related Disorders; Pilot Projects; Risk Factors; Sex Characteristics	2009
Outpatient versus inpatient opioid detoxification: a randomized controlled trial. Journal of substance abuse treatment, 2011, Volume: 40, Issue:1 Topics: Analgesics, Opioid; Clonidine; Female; Heroin; Heroin Dependence; Humans; Inpatients; Male; Methadone; Narcotics; Opioid-Related Disorders; Outcome Assessment, Health Care; Outpatients; Substance Withdrawal Syndrome; Substance-Related Disorders; Treatment Outcome	2011
A comparison of buprenorphine and lofexidine for community opiate detoxification: results from a randomized controlled trial. Addiction (Abingdon, England), 2005, Volume: 100, Issue:12 Topics: Adolescent; Adult; Buprenorphine; Clonidine; Community Mental Health Services; Female; Humans; Male; Middle Aged; Narcotic Antagonists; Opioid-Related Disorders; Treatment Outcome	2005
In-patient detoxification procedures, treatment retention, and post-treatment opiate use: comparison of lofexidine + naloxone, lofexidine + placebo, and methadone. Drug and alcohol dependence, 2007, Apr-17, Volume: 88, Issue:1 Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Analgesics, Opioid; Clonidine; Cohort Studies; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Length of Stay; Male; Methadone; Middle Aged; Naloxone; Narcotic Antagonists; Opioid-Related Disorders; Recurrence; Substance Abuse Treatment Centers; Substance Withdrawal Syndrome; Treatment Outcome	2007
Effects of lofexidine on stress-induced and cue-induced opioid craving and opioid abstinence rates: preliminary findings. Psychopharmacology, 2007, Volume: 190, Issue:4 Topics: Adult; Behavior, Addictive; Clonidine; Cues; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Secondary Prevention; Stress, Psychological; Substance Withdrawal Syndrome; Time Factors; Treatment Outcome	2007
Opiate withdrawal using lofexidine, a clonidine analogue with fewer side effects. The Journal of clinical psychiatry, 1983, Volume: 44, Issue:9 Topics: Adult; Ambulatory Care; Antihypertensive Agents; Clinical Trials as Topic; Clonidine; Humans; Male; Methadone; Methadyl Acetate; Opioid-Related Disorders; Substance Withdrawal Syndrome	1983
Double-blind study of lofexidine and clonidine in the detoxification of opiate addicts in hospital. Drug and alcohol dependence, 1997, Jan-10, Volume: 44, Issue:1 Topics: Adrenergic alpha-Agonists; Adult; Clonidine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Narcotic Antagonists; Neurologic Examination; Opioid-Related Disorders; Patient Admission; Substance Withdrawal Syndrome	1997
Accelerated lofexidine treatment regimen compared with conventional lofexidine and methadone treatment for in-patient opiate detoxification. Drug and alcohol dependence, 1998, May-01, Volume: 50, Issue:3 Topics: Adult; Analysis of Variance; Chi-Square Distribution; Clonidine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hypotension; Male; Methadone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Severity of Illness Index; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors; Treatment Outcome	1998
Randomised double-blind comparison of lofexidine and clonidine in the out-patient treatment of opiate withdrawal. Drug and alcohol dependence, 1998, May-01, Volume: 50, Issue:3 Topics: Adrenergic alpha-Agonists; Adult; Ambulatory Care; Blood Pressure; Chi-Square Distribution; Clonidine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Methadone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Severity of Illness Index; Substance Withdrawal Syndrome; Time Factors; Treatment Outcome	1998
Naltrexone and lofexidine combination treatment compared with conventional lofexidine treatment for in-patient opiate detoxification. Drug and alcohol dependence, 2000, May-01, Volume: 59, Issue:2 Topics: Adult; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Heroin Dependence; Humans; Male; Methadone; Naltrexone; Narcotic Antagonists; Neurologic Examination; Opioid-Related Disorders; Substance Abuse Treatment Centers; Substance Withdrawal Syndrome	2000
Lofexidine versus clonidine in rapid opiate detoxification. Journal of substance abuse treatment, 2001, Volume: 21, Issue:1 Topics: Adult; Analysis of Variance; Clonidine; Double-Blind Method; Humans; Inactivation, Metabolic; Male; Naloxone; Opioid-Related Disorders; Opium; Substance Withdrawal Syndrome; Time Factors	2001
Prison based detoxification for opioid dependence: a randomised double blind controlled trial of lofexidine and methadone. Drug and alcohol dependence, 2002, Jul-01, Volume: 67, Issue:2 Topics: Adult; Analysis of Variance; Chi-Square Distribution; Clonidine; Double-Blind Method; Humans; Male; Methadone; Middle Aged; Opioid-Related Disorders; Prisons; Substance Withdrawal Syndrome	2002
Another trial that failed. Lancet (London, England), 1988, Mar-05, Volume: 1, Issue:8584 Topics: Attitude of Health Personnel; Clinical Trials as Topic; Clonidine; Double-Blind Method; Humans; Opioid-Related Disorders; Random Allocation; Research Support as Topic; Substance Withdrawal Syndrome	1988

Other Studies

18 other study(ies) available for lofexidine and Opioid-Related Disorders

Article	Year
FDA approves nonopioid medication for managing opioid withdrawal. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2018, Jul-01, Volume: 75, Issue:13 Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics, Opioid; Clonidine; Drug Approval; Humans; Narcotic Antagonists; Opioid-Related Disorders; Substance Withdrawal Syndrome; United States; United States Food and Drug Administration	2018
Lofexidine (Lucemyra) for opioid withdrawal. The Medical letter on drugs and therapeutics, 2018, 07-16, Volume: 60, Issue:1551 Topics: Clonidine; Drug Approval; Drug Interactions; Humans; Narcotic Antagonists; Opioid-Related Disorders; Randomized Controlled Trials as Topic; Substance Withdrawal Syndrome; United States; United States Food and Drug Administration	2018
Management of opioid withdrawal symptoms. The Medical letter on drugs and therapeutics, 2018, 08-27, Volume: 60, Issue:1554 Topics: Adrenergic alpha-2 Receptor Agonists; Buprenorphine; Clonidine; Humans; Methadone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Substance Withdrawal Syndrome	2018
Expanded table: Some drugs for management of opioid withdrawal symptoms. The Medical letter on drugs and therapeutics, 2018, 08-27, Volume: 60, Issue:1554 Topics: Adrenergic alpha-2 Receptor Agonists; Buprenorphine; Clonidine; Humans; Methadone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Substance Withdrawal Syndrome	2018
Lofexidine (Lucemyra) for Treatment of Opioid Withdrawal Symptoms. American family physician, 2019, 03-15, Volume: 99, Issue:6 Topics: Adrenergic alpha-2 Receptor Agonists; Clonidine; Dose-Response Relationship, Drug; Humans; Opioid-Related Disorders; Substance Withdrawal Syndrome	2019
The preclinical discovery of lofexidine for the treatment of opiate addiction. Expert opinion on drug discovery, 2014, Volume: 9, Issue:11 Topics: Animals; Clonidine; Drug Discovery; Humans; Narcotic Antagonists; Opioid-Related Disorders	2014
Psychometric evaluation of the 10-item Short Opiate Withdrawal Scale-Gossop (SOWS-Gossop) in patients undergoing opioid detoxification. Addictive behaviors, 2016, Volume: 60 Topics: Adult; Clonidine; Factor Analysis, Statistical; Female; Humans; Male; Narcotic Antagonists; Opioid-Related Disorders; Psychometrics; Reproducibility of Results; Substance Withdrawal Syndrome; Surveys and Questionnaires	2016
Urine and plasma pharmacokinetics of lofexidine after oral delivery in opiate-dependent patients. The American journal of drug and alcohol abuse, 2009, Volume: 35, Issue:5 Topics: Administration, Oral; Adult; Analysis of Variance; Area Under Curve; Chromatography, Liquid; Clonidine; Drug Administration Schedule; Half-Life; Humans; Middle Aged; Narcotic Antagonists; Opioid-Related Disorders; Pilot Projects; Tandem Mass Spectrometry	2009
Opioid dependence. American family physician, 2012, Sep-15, Volume: 86, Issue:6 Topics: Buprenorphine; Clonidine; Evidence-Based Medicine; Humans; Inactivation, Metabolic; Methadone; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Opiate Substitution Treatment; Opioid-Related Disorders; Prognosis; Risk Factors; Substance Withdrawal Syndrome; Time Factors	2012
Induction of patients with moderately severe methadone dependence onto buprenorphine. Addiction biology, 2005, Volume: 10, Issue:2 Topics: Adult; Buprenorphine; Clonidine; Drug Administration Schedule; Female; Humans; Male; Methadone; Narcotic Antagonists; Opioid-Related Disorders; Severity of Illness Index; Surveys and Questionnaires	2005
Lofexidine, a clonidine analogue effective in opiate withdrawal. Lancet (London, England), 1981, May-02, Volume: 1, Issue:8227 Topics: Clonidine; Humans; Opioid-Related Disorders; Substance Withdrawal Syndrome	1981
Recent advances in opiate detoxification: clonidine and lofexidine. NIDA research monograph, 1983, Volume: 43 Topics: Clonidine; Humans; Methadone; Naltrexone; Opioid-Related Disorders; Substance Withdrawal Syndrome	1983
Opiate detoxification using lofexidine. NIDA research monograph, 1982, Volume: 41 Topics: Antihypertensive Agents; Clonidine; Humans; Male; Methadone; Opioid-Related Disorders	1982
Lofexidine blocks acute opiate withdrawal. NIDA research monograph, 1982, Volume: 41 Topics: Antihypertensive Agents; Clonidine; Humans; Methadone; Opioid-Related Disorders; Substance Withdrawal Syndrome	1982
Lofexidine based regimen for opiate addicts. The British journal of general practice : the journal of the Royal College of General Practitioners, 1995, Volume: 45, Issue:393 Topics: Clonidine; Humans; Opioid-Related Disorders; Pilot Projects; Substance Withdrawal Syndrome	1995
A naturalistic study of home detoxification from opiates using lofexidine. Journal of psychopharmacology (Oxford, England), 1998, Volume: 12, Issue:1 Topics: Adult; Clonidine; Female; Heroin Dependence; Humans; Inactivation, Metabolic; Male; Methadone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Treatment Outcome	1998
The use of lofexidine by drug dependency units in the United Kingdom. European addiction research, 1999, Volume: 5, Issue:1 Topics: Adolescent; Adult; Clonidine; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Narcotic Antagonists; Opioid-Related Disorders; Substance Abuse Treatment Centers; Surveys and Questionnaires; United Kingdom	1999
Two methods of community detoxification from opiates: an open-label comparison of lofexidine and buprenorphine. Drug and alcohol dependence, 2001, Dec-01, Volume: 65, Issue:1 Topics: Adult; Buprenorphine; Chi-Square Distribution; Clonidine; Community Health Services; Female; Humans; Logistic Models; Male; Narcotic Antagonists; Opioid-Related Disorders; Outcome Assessment, Health Care; Prospective Studies; Statistics, Nonparametric; Substance Withdrawal Syndrome	2001