Page last updated: 2024-08-23

lofexidine and Cocaine Abuse

lofexidine has been researched along with Cocaine Abuse in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fivel, PA; Kohut, SJ; Mello, NK1
Anderson, A; Chen, CY; De La Garza, R; Dib, E; Galloway, GP; Haile, CN; Hawkins, RY; Kahn, R; Lao, G; Mahoney, JJ; Mendelson, J; Mojsiak, J; Newton, TF1
Erb, S; Hitchcott, PK; Mueller, D; Rajabi, H; Shaham, Y; Stewart, J1
Grimm, JW; Highfield, D; Shaham, Y; Shalev, U; Yap, J1

Trials

1 trial(s) available for lofexidine and Cocaine Abuse

ArticleYear
Assessment of safety, cardiovascular and subjective effects after intravenous cocaine and lofexidine.
    Progress in neuro-psychopharmacology & biological psychiatry, 2014, Apr-03, Volume: 50

    Topics: Adolescent; Adrenergic alpha-2 Receptor Agonists; Adult; Behavior, Addictive; Blood Pressure; Clonidine; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Interactions; Drug Users; Female; Heart Rate; Humans; Infusions, Intravenous; Male; Middle Aged; Young Adult

2014

Other Studies

3 other study(ies) available for lofexidine and Cocaine Abuse

ArticleYear
Differential effects of acute and chronic treatment with the α2-adrenergic agonist, lofexidine, on cocaine self-administration in rhesus monkeys.
    Drug and alcohol dependence, 2013, Dec-01, Volume: 133, Issue:2

    Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Behavior, Animal; Catheterization, Peripheral; Clonidine; Cocaine-Related Disorders; Conditioning, Operant; Dose-Response Relationship, Drug; Food; Macaca mulatta; Male; Reinforcement Schedule; Self Administration

2013
Alpha-2 adrenergic receptor agonists block stress-induced reinstatement of cocaine seeking.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2000, Volume: 23, Issue:2

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Catheterization; Clonidine; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Electric Stimulation; Guanabenz; Infusions, Intravenous; Injections, Intraperitoneal; Male; Microdialysis; Narcotic Antagonists; Norepinephrine; Rats; Rats, Long-Evans; Self Administration; Stress, Physiological; Sucrose

2000
Repeated lofexidine treatment attenuates stress-induced, but not drug cues-induced reinstatement of a heroin-cocaine mixture (speedball) seeking in rats.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2001, Volume: 25, Issue:3

    Topics: Adrenergic alpha-Agonists; Animals; Body Weight; Clonidine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Drug Combinations; Electroshock; Extinction, Psychological; Heroin Dependence; Male; Rats; Rats, Long-Evans; Self Administration; Stress, Psychological

2001