lofepramine has been researched along with Panic Disorder in 2 studies
Lofepramine: A psychotropic IMIPRAMINE derivative that acts as a tricyclic antidepressant and possesses few anticholinergic properties. It is metabolized to DESIPRAMINE.
Panic Disorder: A type of anxiety disorder characterized by unexpected panic attacks that last minutes or, rarely, hours. Panic attacks begin with intense apprehension, fear or terror and, often, a feeling of impending doom. Symptoms experienced during a panic attack include dyspnea or sensations of being smothered; dizziness, loss of balance or faintness; choking sensations; palpitations or accelerated heart rate; shakiness; sweating; nausea or other form of abdominal distress; depersonalization or derealization; paresthesias; hot flashes or chills; chest discomfort or pain; fear of dying and fear of not being in control of oneself or going crazy. Agoraphobia may also develop. Similar to other anxiety disorders, it may be inherited as an autosomal dominant trait.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Among 79 volunteer, unpaid, family doctor-referred psychiatric out patients with DSM III-R panic disorder, with and without agoraphobia, 66 completed a six week placebo-controlled trial of lofepramine versus clomipramine and 57 survivors were followed up for 6 months." | 9.07 | The Galway Study of Panic Disorder. I: Clomipramine and lofepramine in DSM III-R panic disorder: a placebo controlled trial. ( Brophy, J; Fahy, TJ; O'Rourke, D; Schazmann, W; Sciascia, S, 1992) |
| "Among 79 volunteer, unpaid, family doctor-referred psychiatric out patients with DSM III-R panic disorder, with and without agoraphobia, 66 completed a six week placebo-controlled trial of lofepramine versus clomipramine and 57 survivors were followed up for 6 months." | 5.07 | The Galway Study of Panic Disorder. I: Clomipramine and lofepramine in DSM III-R panic disorder: a placebo controlled trial. ( Brophy, J; Fahy, TJ; O'Rourke, D; Schazmann, W; Sciascia, S, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| O'Rourke, D | 2 |
| Fahy, TJ | 2 |
| Prescott, P | 1 |
| Brophy, J | 1 |
| Schazmann, W | 1 |
| Sciascia, S | 1 |
2 trials available for lofepramine and Panic Disorder
| Article | Year |
|---|---|
The Galway Study of Panic Disorder. IV. Temporal stability of diagnosis by present state examination test-retest.
Topics: Antidepressive Agents, Tricyclic; Clomipramine; Double-Blind Method; Follow-Up Studies; Humans; Lofe | 1996 |
The Galway Study of Panic Disorder. I: Clomipramine and lofepramine in DSM III-R panic disorder: a placebo controlled trial.
Topics: Adult; Agoraphobia; Behavior Therapy; Clomipramine; Combined Modality Therapy; Female; Humans; Lofep | 1992 |