lofepramine and Atrophy studies

Lofepramine: A psychotropic IMIPRAMINE derivative that acts as a tricyclic antidepressant and possesses few anticholinergic properties. It is metabolized to DESIPRAMINE.

Atrophy: Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes.

Research Excerpts

Excerpt	Relevance	Reference
"As part of a large, randomized placebo-controlled trial of inpatients with multiple sclerosis (MS), a subsample of 15 underwent cerebral MRI at baseline and 6-months (eight on lofepramine and l-phenylalanine; seven on placebo)."	9.09	MRI changes in multiple sclerosis following treatment with lofepramine and L-phenylalanine. ( Al Saffar, BY; Bydder, GM; Chaudhuri, KR; Curati, WL; Hajnal, JV; Horrobin, DF; Mitchell, L; Puri, BK; White, SJ, 2001)
"As part of a large, randomized placebo-controlled trial of inpatients with multiple sclerosis (MS), a subsample of 15 underwent cerebral MRI at baseline and 6-months (eight on lofepramine and l-phenylalanine; seven on placebo)."	5.09	MRI changes in multiple sclerosis following treatment with lofepramine and L-phenylalanine. ( Al Saffar, BY; Bydder, GM; Chaudhuri, KR; Curati, WL; Hajnal, JV; Horrobin, DF; Mitchell, L; Puri, BK; White, SJ, 2001)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

lofepramine and Atrophy

Research Excerpts

Research

Studies (1)

Authors

Trials

Authors	Studies
Puri, BK	1
Bydder, GM	1
Chaudhuri, KR	1
Al Saffar, BY	1
Curati, WL	1
White, SJ	1
Mitchell, L	1
Hajnal, JV	1
Horrobin, DF	1