Page last updated: 2024-10-30

lofepramine and Atrophy

lofepramine has been researched along with Atrophy in 1 studies

Lofepramine: A psychotropic IMIPRAMINE derivative that acts as a tricyclic antidepressant and possesses few anticholinergic properties. It is metabolized to DESIPRAMINE.

Atrophy: Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes.

Research Excerpts

ExcerptRelevanceReference
"As part of a large, randomized placebo-controlled trial of inpatients with multiple sclerosis (MS), a subsample of 15 underwent cerebral MRI at baseline and 6-months (eight on lofepramine and l-phenylalanine; seven on placebo)."9.09MRI changes in multiple sclerosis following treatment with lofepramine and L-phenylalanine. ( Al Saffar, BY; Bydder, GM; Chaudhuri, KR; Curati, WL; Hajnal, JV; Horrobin, DF; Mitchell, L; Puri, BK; White, SJ, 2001)
"As part of a large, randomized placebo-controlled trial of inpatients with multiple sclerosis (MS), a subsample of 15 underwent cerebral MRI at baseline and 6-months (eight on lofepramine and l-phenylalanine; seven on placebo)."5.09MRI changes in multiple sclerosis following treatment with lofepramine and L-phenylalanine. ( Al Saffar, BY; Bydder, GM; Chaudhuri, KR; Curati, WL; Hajnal, JV; Horrobin, DF; Mitchell, L; Puri, BK; White, SJ, 2001)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Puri, BK1
Bydder, GM1
Chaudhuri, KR1
Al Saffar, BY1
Curati, WL1
White, SJ1
Mitchell, L1
Hajnal, JV1
Horrobin, DF1

Trials

1 trial available for lofepramine and Atrophy

ArticleYear
MRI changes in multiple sclerosis following treatment with lofepramine and L-phenylalanine.
    Neuroreport, 2001, Jul-03, Volume: 12, Issue:9

    Topics: Adult; Antidepressive Agents, Tricyclic; Atrophy; Cerebral Cortex; Drug Therapy, Combination; Female

2001