lobenzarit has been researched along with Arthritis, Rheumatoid in 12 studies
lobenzarit: prevents autoimmune kidney disease in hybrid mice; RN given refers to parent cpd
Arthritis, Rheumatoid: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A multicenter double-blind study was carried out in patients with rheumatoid arthritis (RA) by comparing treatment with a novel immunomodulator, lobenzarit, disodium 4-chloro-2, 2'-iminodibenzoate, with an inert placebo." | 9.05 | A multicenter double-blind controlled study of lobenzarit, a novel immunomodulator, in rheumatoid arthritis. ( Abe, C; Honma, M; Horiuchi, Y; Kageyama, T; Mizushima, Y; Ofuji, T; Ogawa, N; Shichikawa, K; Shiokawa, Y; Yoshizawa, H, 1984) |
| "Nephrogenic diabetes insipidus (NDI) occurred in a 43-year-old woman who had received lobenzarit disodium for the treatment of rheumatoid arthritis (RA)." | 8.79 | Nephrogenic diabetes insipidus induced by lobenzarit disodium treatment in patients with rheumatoid arthritis. ( Kondo, M; Miyazaki, R; Sakane, N; Umekawa, T; Yoshida, T, 1996) |
| "A multicenter double-blind study was carried out in patients with rheumatoid arthritis (RA) by comparing treatment with a novel immunomodulator, lobenzarit, disodium 4-chloro-2, 2'-iminodibenzoate, with an inert placebo." | 5.05 | A multicenter double-blind controlled study of lobenzarit, a novel immunomodulator, in rheumatoid arthritis. ( Abe, C; Honma, M; Horiuchi, Y; Kageyama, T; Mizushima, Y; Ofuji, T; Ogawa, N; Shichikawa, K; Shiokawa, Y; Yoshizawa, H, 1984) |
| "Nephrogenic diabetes insipidus (NDI) occurred in a 43-year-old woman who had received lobenzarit disodium for the treatment of rheumatoid arthritis (RA)." | 4.79 | Nephrogenic diabetes insipidus induced by lobenzarit disodium treatment in patients with rheumatoid arthritis. ( Kondo, M; Miyazaki, R; Sakane, N; Umekawa, T; Yoshida, T, 1996) |
| "Lobenzarit (disodium 4-chloro-2,2'-iminodibenzoate [CCA]) is a novel disease-modifying drug for the treatment of rheumatoid arthritis (RA)." | 3.68 | Regulation of B cell function by lobenzarit, a novel disease-modifying antirheumatic drug. ( Hirohata, S; Inoue, T; Lipsky, PE; Miyamoto, T; Shinohara, S, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (41.67) | 18.7374 |
| 1990's | 7 (58.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Itoh, K | 1 |
| Saitoh, F | 1 |
| Kumagai, K | 1 |
| Kosaka, S | 1 |
| Ohara, M | 1 |
| Igarashi, S | 1 |
| Kobashi, C | 1 |
| Nanamiya, M | 1 |
| Yoshida, H | 1 |
| Kasukawa, R | 1 |
| Shiokawa, Y | 1 |
| Horiuchi, Y | 1 |
| Mizushima, Y | 1 |
| Kageyama, T | 1 |
| Shichikawa, K | 1 |
| Ofuji, T | 1 |
| Honma, M | 1 |
| Yoshizawa, H | 1 |
| Abe, C | 1 |
| Ogawa, N | 1 |
| Sonozaki, H | 1 |
| Mitsui, H | 1 |
| Minami, M | 1 |
| Kaneda, K | 1 |
| Sakane, N | 1 |
| Yoshida, T | 1 |
| Umekawa, T | 1 |
| Miyazaki, R | 1 |
| Kondo, M | 1 |
| Nakano, M | 1 |
| Nishi, S | 1 |
| Ueno, M | 1 |
| Saito, T | 1 |
| Hasegawa, H | 1 |
| Arakawa, M | 1 |
| Nishinarita, S | 1 |
| Hayakawa, J | 1 |
| Suzuki, R | 1 |
| Hayama, T | 1 |
| Hiranuma, M | 1 |
| Sawada, S | 1 |
| Horie, T | 1 |
| Nishioka, K | 1 |
| Azuma, T | 1 |
| Iwasaki, Y | 1 |
| Ichinohe, T | 1 |
| Kuwahara, T | 1 |
| Yata, K | 1 |
| Seo, T | 1 |
| Suyama, K | 1 |
| Onaka, H | 1 |
| Ono, T | 1 |
| Ueda, S | 1 |
| Matsuo, T | 1 |
| Hirohata, S | 1 |
| Shinohara, S | 1 |
| Inoue, T | 1 |
| Miyamoto, T | 1 |
| Lipsky, PE | 1 |
| Taneichi, K | 1 |
| Watanabe, I | 1 |
| Sakai, I | 1 |
| Shibaki, H | 1 |
2 reviews available for lobenzarit and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Nephrogenic diabetes insipidus induced by lobenzarit disodium treatment in patients with rheumatoid arthritis.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Diabetes Insipidus, Nephrogen | 1996 |
[Drug-induced renal disorders in patients with rheumatoid arthritis].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Cyclosporine; | 1996 |
3 trials available for lobenzarit and Arthritis, Rheumatoid
| Article | Year |
|---|---|
A multicenter double-blind controlled study of lobenzarit, a novel immunomodulator, in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Blood Sedimentation; Clinical Trials as Topic; Double-Blind Method; Drug Ther | 1984 |
[A long-term clinical analysis of the rheumatoid patients treated by a combination of GST and CCA].
Topics: Activities of Daily Living; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antirh | 1995 |
[A double blind comparative study between salazosulfapyridine enteric coated tablets (PJ-306) and lobenzarit disodium (CCA) in rheumatoid arthritis].
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Double-Blin | 1991 |
7 other studies available for lobenzarit and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Depressed natural killer activity in rheumatoid arthritis and its in vitro augmentation with interferon and N-(2-carboxyphenyl)-4-chloroanthranilic acid disodium salt (CCA), an anti-arthritis agent.
Topics: Adult; Aged; Arthritis, Rheumatoid; Cytotoxicity, Immunologic; Female; Humans; Interferons; Killer C | 1981 |
The effects of the antirheumatic agents N-(2-carboxyphenyl)-4-chloroanthranilic acid disodium (CCA) and D-penicillamine on the NK and ADCC activities and interferon production of lymphocytes.
Topics: Antibody-Dependent Cell Cytotoxicity; Arthritis, Rheumatoid; Humans; In Vitro Techniques; Interferon | 1984 |
[Effects of CCA on abnormalities of T-lymphocytes in patients with rheumatoid arthritis].
Topics: Antibodies, Monoclonal; Arthritis, Rheumatoid; Humans; Leukocyte Count; ortho-Aminobenzoates; T-Lymp | 1984 |
[Lobenzarit disodium (CCA)--induced diabetes insipidus in a patient with rheumatoid arthritis].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Diabetes Insipidus; Female; H | 1992 |
[Recurrent hyperkalemia in the course of rheumatoid arthritis--a case report].
Topics: Adrenergic beta-Antagonists; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; F | 1991 |
Regulation of B cell function by lobenzarit, a novel disease-modifying antirheumatic drug.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; B-Lymphocytes; Cell Cycle; Cells, Cu | 1992 |
[Association of immunomodulators and HLA antigens in rheumatoid arthritis].
Topics: Adjuvants, Immunologic; Adult; Aged; Arthritis, Rheumatoid; Auranofin; Female; HLA Antigens; Humans; | 1989 |