Page last updated: 2024-09-03

lithospermate b and Disease Models, Animal

lithospermate b has been researched along with Disease Models, Animal in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (6.67)18.2507
2000's0 (0.00)29.6817
2010's12 (80.00)24.3611
2020's2 (13.33)2.80

Authors

AuthorsStudies
Deng, Q; Luo, X; Pan, G; Peng, H; Wu, Z; Xuan, L; Xue, Y; Zhang, T1
Duo, D; He, R; Wang, Y; Wu, X; Yan, Y1
Liu, J; Shen, JH; Wang, K; Zhang, QL; Zhao, J1
Chen, G; Chen, T; Dou, Z; Fan, L; He, P; Li, J; Peng, Y; Ruan, W; Xu, H1
Li, NS; Li, T; Liu, B; Luo, XJ; Peng, J; Peng, JJ; Song, FL; Wang, EL; Yang, JF1
Wang, C; Wang, M; Yang, J; Yang, L; Zhou, Y1
Guo, C; Quan, W; Wang, Y; Wei, G; Wen, A; Weng, Y; Xi, M; Zhou, D; Zhu, Y1
Ding, G; Fu, Z; Guo, W; Liu, F; Liu, W; Song, S; Wang, Z1
Chang, CZ; Kwan, AL; Wu, SC1
Budohoski, KP; Bulters, DO; Helmy, A; Karri, SK; Kirkpatrick, PJ; Kirollos, RW; Ogilvy, CS; Trivedi, RA; Young, AM1
Liu, F; Quan, W; Wang, L; Wu, B; Wu, Q; Xie, C; Yin, J; Zhang, W; Zhang, X; Zhang, Y1
Liu, B; Lou, Z; Luo, XJ; Ma, QL; Peng, J; Peng, JJ; Ren, KD; Ren, X; Tan, B; Yang, J; Yang, ZB1
Ahn, DS; Cho, JW; Choi, M; Jung, M; Kang, ES; Kim, SH; Kim, YH; Kim, YO; Lee, EJ; Lee, HC; Lee, Y; Williams, DR1
Chang, CZ; Howng, SL; Hwang, SL; Kwan, AL; Wu, SC1
Arima, T; Hattori, M; Kadota, S; Namba, T; Nomura, Y1

Other Studies

15 other study(ies) available for lithospermate b and Disease Models, Animal

ArticleYear
Anti-Fibrosis Effects of Magnesium Lithospermate B in Experimental Pulmonary Fibrosis: By Inhibiting TGF-βRI/Smad Signaling.
    Molecules (Basel, Switzerland), 2021, Mar-19, Volume: 26, Issue:6

    Topics: Animals; Bleomycin; Disease Models, Animal; Drugs, Chinese Herbal; Male; Mice; Pulmonary Fibrosis; Receptor, Transforming Growth Factor-beta Type I; Signal Transduction; Smad Proteins

2021
Magnesium lithospermate B ameliorates hypobaric hypoxia-induced pulmonary arterial hypertension by inhibiting endothelial-to-mesenchymal transition and its potential targets.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 130

    Topics: Animals; Biomarkers; Disease Management; Disease Models, Animal; Disease Susceptibility; Drugs, Chinese Herbal; Endothelium, Vascular; Gene Expression; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Rats; Signal Transduction

2020
Magnesium lithospermate B improves the gut microbiome and bile acid metabolic profiles in a mouse model of diabetic nephropathy.
    Acta pharmacologica Sinica, 2019, Volume: 40, Issue:4

    Topics: Animals; Bile Acids and Salts; Computational Biology; Diabetic Nephropathies; Disease Models, Animal; Drugs, Chinese Herbal; Gastrointestinal Microbiome; Kidney Function Tests; Male; Mice; Mice, Inbred DBA

2019
Neuroprotective Effects of Magnesium Lithospermate B against Subarachnoid Hemorrhage in Rats.
    The American journal of Chinese medicine, 2018, Volume: 46, Issue:6

    Topics: Animals; Apoptosis; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Inflammation Mediators; Infusions, Parenteral; Male; Microglia; Neurons; Neuroprotective Agents; NF-kappa B; Phytotherapy; Rats, Sprague-Dawley; Salvia miltiorrhiza; Signal Transduction; Sirtuin 1; Subarachnoid Hemorrhage; Tumor Necrosis Factor-alpha

2018
Magnesium Lithospermate B Derived from Salvia miltiorrhiza Ameliorates Right Ventricle Remodeling in Pulmonary Hypertensive Rats via Inhibition of NOX/VPO1 Pathway.
    Planta medica, 2019, Volume: 85, Issue:9-10

    Topics: Animals; Atrial Natriuretic Factor; Benzoxazoles; Cell Hypoxia; Cell Line; Disease Models, Animal; Drugs, Chinese Herbal; Hemeproteins; Hypertension, Pulmonary; Male; Myocytes, Cardiac; NADPH Oxidase 2; NADPH Oxidase 4; NADPH Oxidases; Natriuretic Peptide, Brain; Peroxidases; Rats, Sprague-Dawley; Salvia miltiorrhiza; Triazoles; Ventricular Remodeling

2019
Magnesium lithospermate B attenuates renal injury in 5/6 renal ablation/infarction rats by mitochondrial pathway of apoptosis.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 118

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cytochromes c; Cytosol; Disease Models, Animal; Drugs, Chinese Herbal; Kidney; Male; Mitochondria; Protein Multimerization; Rats, Sprague-Dawley; Renal Insufficiency, Chronic; Tumor Suppressor Protein p53

2019
Magnesium lithospermate B reduces myocardial ischemia/reperfusion injury in rats via regulating the inflammation response.
    Pharmaceutical biology, 2013, Volume: 51, Issue:11

    Topics: Animals; Anti-Inflammatory Agents; Biomarkers; Creatine Kinase, MB Form; Cytokines; Disease Models, Animal; Drugs, Chinese Herbal; Electrocardiography; I-kappa B Proteins; Inflammation; Inflammation Mediators; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; NF-kappa B; NF-KappaB Inhibitor alpha; Peroxidase; Phosphorylation; Rats; Rats, Sprague-Dawley; Signal Transduction; Time Factors; Troponin I

2013
Magnesium lithospermate B reduces inflammatory response in a mouse model of hepatic ischemia-reperfusion injury.
    Cell biochemistry and biophysics, 2014, Volume: 69, Issue:2

    Topics: Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; CD11b Antigen; Chemokine CXCL10; Disease Models, Animal; Drugs, Chinese Herbal; Inflammation Mediators; Intercellular Adhesion Molecule-1; Interleukin-6; Liver; Macrophages; Male; Mice; Mice, Inbred C57BL; Neutrophils; Peroxidase; Reperfusion Injury; Signal Transduction; Tumor Necrosis Factor-alpha

2014
Magnesium lithospermate B, an active extract of Salvia miltiorrhiza, mediates sGC/cGMP/PKG translocation in experimental vasospasm.
    BioMed research international, 2014, Volume: 2014

    Topics: Animals; Biological Transport, Active; Camphanes; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Disease Models, Animal; Drugs, Chinese Herbal; Guanylate Cyclase; Male; Panax notoginseng; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Salvia miltiorrhiza; Signal Transduction; Soluble Guanylyl Cyclase; Vasospasm, Intracranial

2014
Pharmacologic Management of Subarachnoid Hemorrhage.
    World neurosurgery, 2015, Volume: 84, Issue:1

    Topics: Adrenal Cortex Hormones; Animals; Anticoagulants; Apoptosis; Brain Ischemia; Calcium Channel Blockers; Clinical Trials as Topic; Dexamethasone; Dioxanes; Disease Models, Animal; Drugs, Chinese Herbal; Estrogens; Evidence-Based Medicine; Free Radical Scavengers; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Magnesium Sulfate; Neuroprotective Agents; Nimodipine; Platelet Aggregation Inhibitors; Pregnatrienes; Progesterone; Pyridines; Pyrimidines; Receptor, Endothelin A; Subarachnoid Hemorrhage; Sulfonamides; Tetrazoles

2015
Antidepressant-like effects of magnesium lithospermate B in a rat model of chronic unpredictable stress.
    Pharmaceutical biology, 2015, Volume: 53, Issue:8

    Topics: Animals; Antidepressive Agents; Chronic Disease; Disease Models, Animal; Drugs, Chinese Herbal; Free Radical Scavengers; Male; Rats; Rats, Sprague-Dawley; Stress, Psychological; Treatment Outcome

2015
Salviaolate Protects Rat Brain from Ischemia-Reperfusion Injury through Inhibition of NADPH Oxidase.
    Planta medica, 2015, Volume: 81, Issue:15

    Topics: Animals; Antioxidants; Benzofurans; Benzoxazoles; Brain; Brain Ischemia; Cells, Cultured; China; Cinnamates; Depsides; Disease Models, Animal; Drugs, Chinese Herbal; Male; NADPH Oxidases; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Rosmarinic Acid; Salvia miltiorrhiza; Triazoles

2015
Natural therapeutic magnesium lithospermate B potently protects the endothelium from hyperglycaemia-induced dysfunction.
    Cardiovascular research, 2010, Sep-01, Volume: 87, Issue:4

    Topics: Animals; Antioxidants; Apoptosis; Cell Adhesion; Cells, Cultured; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Disease Models, Animal; Drugs, Chinese Herbal; Endothelium, Vascular; Glucose; Glycation End Products, Advanced; Glycosylation; Heme Oxygenase-1; Humans; Leukocytes; NF-E2-Related Factor 2; Nitric Oxide Synthase Type III; Nitrites; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Rats; Rats, Inbred OLETF; Rats, Long-Evans; Reactive Oxygen Species; Time Factors; Vasodilation

2010
Magnesium lithospermate B alleviates the production of endothelin-1 through an NO-dependent mechanism and reduces experimental vasospasm in rats.
    Acta neurochirurgica, 2011, Volume: 153, Issue:11

    Topics: Animals; Disease Models, Animal; Drugs, Chinese Herbal; Endothelin-1; Free Radical Scavengers; Male; Nitric Oxide; Rats; Rats, Sprague-Dawley; Subarachnoid Hemorrhage; Vasospasm, Intracranial

2011
[Ameliorating effects of dan-shen and its major ingredient calcium/magnesium lithospermate B on cognitive deficiencies in senescence-accelerated mouse].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1997, Volume: 110 Suppl 1

    Topics: Aging; Animals; Cognition; Disease Models, Animal; Drug Combinations; Drugs, Chinese Herbal; Learning; Learning Disabilities; Male; Memory; Mice; Mice, Inbred Strains; Motor Activity; Phenanthrolines; Plant Extracts; Reaction Time; Salvia miltiorrhiza

1997