Page last updated: 2024-08-21

lithocholic acid and Liver Dysfunction

lithocholic acid has been researched along with Liver Dysfunction in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199021 (55.26)18.7374
1990's4 (10.53)18.2507
2000's3 (7.89)29.6817
2010's7 (18.42)24.3611
2020's3 (7.89)2.80

Authors

AuthorsStudies
Bai, LP; Deng, W; Guo, Z; Kuok, H; Lei, K; Li, T; Qin, H; Tang, Y; Xiao, R; Zhuang, Y1
Eguchi, A; Iwasa, M; Kitamura, H; Kobayashi, Y; Nakagawa, H; Shigefuku, R; Sugimoto, R; Takei, Y; Tamai, Y; Tempaku, M1
Combalia, A; Dubreuil, M; Guañabens, N; Jurado, S; Monegal, A; Parés, A; Peris, P; Ruiz-Gaspà, S1
Ahmed, N; Almaramhy, HH; Alrohily, WD; Bojan, B; El-Agamy, DS; Elkablawy, MA1
Gao, YJ; Han, JC; Yu, J1
Curtis, JM; Lim, DW; Mager, DR; Mazurak, VC; Mi, S; Sigalet, DL; Turner, JM; Wales, PW; Wizzard, PR; Yap, JY1
Amano, K; Masubuchi, N; Matsuura, T; Nakano, M; Sugihara, M; Sugita, T1
Alicandro, G; Biffi, A; Colombo, C; Corti, F; Crosignani, A; Motta, V; Setchell, KDR; Zhang, W1
Bae, SH; Choi, JH; Jun, JH; Kim, GJ; Oh, SH1
Hori, W; Miyata, M; Mizuki, T; Nagayasu, M; Ninomiya, S; Nomoto, M; Sotodate, F; Yamazoe, Y; Yokokawa, S1
Denk, H; Fickert, P; Fuchsbichler, A; Jaeschke, H; Krause, R; Marschall, HU; Trauner, M; Wagner, M; Zatloukal, K; Zollner, G1
Elias, E; Mills, CO1
Matsui, A; Setchell, KD1
Díaz, M; Fay, O; Jorge, A; Palazzi, J; Sánchez, D; Tanno, H1
Baker, D; Gochman, N; Javitt, NB; Jones, HM; Miyai, K1
Balistreri, WF; Farrell, MK; Heubi, JE; Suchy, FJ1
Biffl, H; Leb, G; Parsché, P; Passath, A; Pristautz, H1
Allan, RN; Dew, MJ; Huybregts, AW; van Berge Henegouwen, GP1
Dionne, S; Plaa, GL; Tuchweber, B; Yousef, IM1
Clayton, PT; Johnson, AW; Lemonde, HA1
Bock, HH; Lammert, F1
Cochrane, AM; Ellis, WR; Hughes, RD; Murray-Lyon, IM; Williams, R1
Bereziat, G; Pepin, D; Polonovski, J; Wolf, C1
Adachi, H; Fukuda, Y; Nakajima, I; Noguchi, M; Sano, M1
Doi, H; Imaeda, T; Suzuki, M1
Ibayashi, H; Ichiya, Y; Kamoi, I; Koga, S; Matsuura, K; Nishitani, H; Oshiumi, Y1
Biffl, H; Goebel, R; Leb, G1
Barnes, S; Morris, JS; Siegel, JH1
Demers, LM; Hepner, GW1
Barnes, S; Brooke, BN; Morris, JS; Siegel, JH1
Hofmann, AF1
Elias, E; Iqbal, S; Vickers, C1
Imoto, M; Okumura, K; Okuyama, S; Satake, T; Sugiyama, K; Takagi, K1
Bijleveld, CM; Fernandes, J; Kneepkens, CM; Kuipers, F; van Zanten, A; Vonk, RJ1
Banwell, JG; Lockwood, DH; Nair, PP; Sherr, HP; White, JJ1
King, JE; Schoenfield, LJ1
Murphy, GM; Signer, E1
Erb, W; Schreiber, J; Walczak, M1

Reviews

3 review(s) available for lithocholic acid and Liver Dysfunction

ArticleYear
Serum bile acid analysis.
    Clinica chimica acta; international journal of clinical chemistry, 1983, Jan-07, Volume: 127, Issue:1

    Topics: Adult; Aged; Bile Acids and Salts; Bile Ducts; Chenodeoxycholic Acid; Child; Child, Preschool; Cholic Acids; Chromatography, Gas; Chromatography, Gel; Deoxycholic Acid; Female; Gas Chromatography-Mass Spectrometry; Humans; Ileum; Lithocholic Acid; Liver Cirrhosis, Biliary; Liver Diseases; Male; Middle Aged

1983
Lithocholic acid, cholestasis, and liver disease.
    Mayo Clinic proceedings, 1972, Volume: 47, Issue:10

    Topics: Animals; Bile; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Cholestasis; Disease Models, Animal; Humans; Hydroxylation; Lithocholic Acid; Liver; Liver Diseases; Solubility; Species Specificity

1972
Bile acid metabolism in infants and children.
    Gut, 1974, Volume: 15, Issue:2

    Topics: Bile; Bile Acids and Salts; Biological Transport, Active; Chenodeoxycholic Acid; Child; Child, Preschool; Cholestasis; Cholesterol; Cholic Acids; Deoxycholic Acid; Humans; Infant; Infant Nutrition Disorders; Infant, Newborn; Lithocholic Acid; Liver; Liver Diseases; Malabsorption Syndromes; Surface Properties

1974

Other Studies

35 other study(ies) available for lithocholic acid and Liver Dysfunction

ArticleYear
Synthesis and identification of lithocholic acid 3-sulfate as RORγt ligand to inhibit Th17 cell differentiation.
    Journal of leukocyte biology, 2022, Volume: 112, Issue:4

    Topics: Bile Acids and Salts; Cell Differentiation; Cholesterol; Humans; Interleukin-17; Ligands; Lipids; Lithocholic Acid; Liver Diseases; Nuclear Receptor Subfamily 1, Group F, Member 3; Sulfates; Th17 Cells; Transcription Factors

2022
Association of lithocholic acid with skeletal muscle hypertrophy through TGR5-IGF-1 and skeletal muscle mass in cultured mouse myotubes, chronic liver disease rats and humans.
    eLife, 2022, 10-07, Volume: 11

    Topics: Amino Acids, Branched-Chain; Animals; Bile Acids and Salts; Humans; Hypertrophy; Insulin-Like Growth Factor I; Lithocholic Acid; Liver Cirrhosis; Liver Diseases; Mice; Muscle Fibers, Skeletal; Muscle, Skeletal; Proto-Oncogene Proteins c-akt; Rats; Receptors, G-Protein-Coupled; Sarcopenia

2022
Bile acids and bilirubin effects on osteoblastic gene profile. Implications in the pathogenesis of osteoporosis in liver diseases.
    Gene, 2020, Jan-30, Volume: 725

    Topics: Apoptosis; Bile Acids and Salts; Bilirubin; Cell Line, Tumor; Cholestasis; Down-Regulation; Genetic Profile; Humans; Lithocholic Acid; Liver; Liver Diseases; Osteoblasts; Osteoporosis; Osteosarcoma; Up-Regulation; Ursodeoxycholic Acid

2020
Anti-Inflammatory Effects of Vardenafil Against Cholestatic Liver Damage in Mice: a Mechanistic Study.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 47, Issue:2

    Topics: Alkaline Phosphatase; Animals; Anti-Inflammatory Agents; Antioxidants; Caspase 1; Cholestasis; Cytokines; Glutamate-Cysteine Ligase; Glutathione; Lithocholic Acid; Liver; Liver Diseases; Male; Mice; NF-E2-Related Factor 2; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Transaminases; Vardenafil Dihydrochloride

2018
Lipidomics investigation of reversal effect of glycyrrhizin (GL) towards lithocholic acid (LCA)-induced alteration of phospholipid profiles.
    Pharmaceutical biology, 2014, Volume: 52, Issue:12

    Topics: Alanine Transaminase; Animals; Glycyrrhizic Acid; Injections, Intraperitoneal; Lipid Metabolism; Lipids; Lithocholic Acid; Liver Diseases; Male; Mice; Mice, Inbred C57BL; Phospholipids

2014
Glucagon-Like Peptide-2 Alters Bile Acid Metabolism in Parenteral Nutrition--Associated Liver Disease.
    JPEN. Journal of parenteral and enteral nutrition, 2016, Volume: 40, Issue:1

    Topics: Animals; Animals, Newborn; Bile Acids and Salts; Cholestasis; Cholesterol 7-alpha-Hydroxylase; Disease Models, Animal; Gene Expression Regulation; Glucagon-Like Peptide 2; Lithocholic Acid; Liver Diseases; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Parenteral Nutrition; Swine; Tandem Mass Spectrometry; Transcriptome

2016
Oxidative stress markers, secondary bile acids and sulfated bile acids classify the clinical liver injury type: Promising diagnostic biomarkers for cholestasis.
    Chemico-biological interactions, 2016, Aug-05, Volume: 255

    Topics: Aged; Bile Acids and Salts; Biomarkers; Cholestasis; Collagen Type IV; Deoxycholic Acid; Female; Humans; Hyaluronic Acid; Lithocholic Acid; Liver Cirrhosis; Liver Diseases; Male; Middle Aged; Oxidative Stress; Reactive Oxygen Species; Sulfates

2016
Long-Term Ursodeoxycholic Acid Therapy Does Not Alter Lithocholic Acid Levels in Patients with Cystic Fibrosis with Associated Liver Disease.
    The Journal of pediatrics, 2016, Volume: 177

    Topics: Adolescent; Adult; Bile Acids and Salts; Biotransformation; Child; Child, Preschool; Cystic Fibrosis; Deoxycholic Acid; Female; Humans; Lithocholic Acid; Liver Diseases; Male; Tandem Mass Spectrometry; Ursodeoxycholic Acid; Young Adult

2016
Decreased C-reactive protein induces abnormal vascular structure in a rat model of liver dysfunction induced by bile duct ligation.
    Clinical and molecular hepatology, 2016, Volume: 22, Issue:3

    Topics: Angiogenic Proteins; Animals; Bile Ducts; C-Reactive Protein; Cells, Cultured; Disease Models, Animal; Hepatic Veins; Hepatocytes; Human Umbilical Vein Endothelial Cells; Humans; Lithocholic Acid; Liver; Liver Cirrhosis; Liver Diseases; Male; Microscopy, Fluorescence; Mitochondria; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; RNA Interference; RNA, Small Interfering; Serum Albumin

2016
Possible protective role of pregnenolone-16 alpha-carbonitrile in lithocholic acid-induced hepatotoxicity through enhanced hepatic lipogenesis.
    European journal of pharmacology, 2010, Jun-25, Volume: 636, Issue:1-3

    Topics: Animals; Biliary Tract; Biomarkers; Fatty Acids; Female; Gene Expression Profiling; Hepatocytes; Lipogenesis; Lithocholic Acid; Liver; Liver Diseases; Mice; Mice, Inbred C57BL; Phosphatidylcholines; Pregnenolone Carbonitrile; Time Factors

2010
Lithocholic acid feeding induces segmental bile duct obstruction and destructive cholangitis in mice.
    The American journal of pathology, 2006, Volume: 168, Issue:2

    Topics: Animals; Bile Acids and Salts; Biliary Tract Diseases; Chemical and Drug Induced Liver Injury; Cholangitis; Cholestasis; Detergents; Diet; Fibrosis; Fluorescence; Lithocholic Acid; Liver; Liver Diseases; Male; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Organic Anion Transporters; Organic Anion Transporters, Sodium-Dependent; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfotransferases; Symporters

2006
Coordinated defence and the liver.
    Clinical medicine (London, England), 2007, Volume: 7, Issue:2

    Topics: Bile Acids and Salts; Biological Transport; Cytochrome P-450 Enzyme System; Disease Susceptibility; Enzyme Induction; Gastrointestinal Diseases; Humans; Lithocholic Acid; Liver; Liver Diseases; Pharmaceutical Preparations; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Xenobiotics

2007
[Determination of cholic and sulfolithocholic acids in various hepatopathies].
    Acta gastroenterologica Latinoamericana, 1982, Volume: 12, Issue:2

    Topics: Chronic Disease; Diet; Fasting; Female; Glycocholic Acid; Hepatitis; Humans; Lithocholic Acid; Liver Cirrhosis; Liver Diseases; Pregnancy; Pregnancy Complications; Pruritus

1982
Hepatotoxicity of bile acids in rabbits: ursodeoxycholic acid is less toxic than chenodeoxycholic acid.
    Laboratory investigation; a journal of technical methods and pathology, 1982, Volume: 46, Issue:4

    Topics: Animals; Bile Canaliculi; Body Weight; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cytoskeleton; Deoxycholic Acid; Lithocholic Acid; Liver; Liver Diseases; Prognosis; Rabbits; Ursodeoxycholic Acid

1982
Pathologic versus physiologic cholestasis: elevated serum concentration of a secondary bile acid in the presence of hepatobiliary disease.
    The Journal of pediatrics, 1981, Volume: 98, Issue:3

    Topics: Biliary Tract Diseases; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Humans; Infant; Infant, Newborn; Lithocholic Acid; Liver Diseases; Sulfates

1981
[Clinical evaluation of serum bile acids as a new liver function test (author's transl)].
    Acta medica Austriaca, 1981, Volume: 7, Issue:2

    Topics: Diagnosis, Differential; Fatty Liver; Glycocholic Acid; Hepatitis; Humans; Lithocholic Acid; Liver Cirrhosis; Liver Diseases; Liver Function Tests; Liver Neoplasms; Radioimmunoassay

1981
Hepatotoxic effect of bile acids in inflammatory bowel disease.
    Gastroenterology, 1980, Volume: 78, Issue:6

    Topics: Adult; Aged; Bile Acids and Salts; Biotransformation; Colitis, Ulcerative; Crohn Disease; Female; Humans; Lithocholic Acid; Liver; Liver Diseases; Male; Middle Aged; Stereoisomerism; Sulfates; Ursodeoxycholic Acid

1980
Phase I and phase II metabolism of lithocholic acid in hepatic acinar zone 3 necrosis. Evaluation in rats by combined radiochromatography and gas-liquid chromatography-mass spectrometry.
    Biochemical pharmacology, 1994, Sep-15, Volume: 48, Issue:6

    Topics: Animals; Bile; Bile Acids and Salts; Bromobenzenes; Carbon Radioisotopes; Cholestasis; Chromatography, Thin Layer; Gas Chromatography-Mass Spectrometry; Glucuronates; Lithocholic Acid; Liver Diseases; Male; Necrosis; Rats; Rats, Sprague-Dawley

1994
The identification of unusual bile acid metabolites by tandem mass spectrometry: use of low-energy collision-induced dissociation to produce informative spectra.
    Rapid communications in mass spectrometry : RCM, 1999, Volume: 13, Issue:12

    Topics: Bile Acids and Salts; Cholic Acids; Glycocholic Acid; Humans; Lithium; Lithocholic Acid; Liver Diseases; Mass Spectrometry; Molecular Structure; Multienzyme Complexes; Peroxisomal Disorders; Progesterone Reductase; Steroid Isomerases

1999
Nuclear xeno-sensors as receptors for cholestatic bile acids: the second line of defense.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Bile Acids and Salts; Cholestasis; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Hydroxylation; Lithocholic Acid; Liver Diseases; Mice; Mice, Knockout; Mice, Transgenic; Oxidoreductases, N-Demethylating; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid

2002
Studies on plasma cytotoxicity and liver regeneration in fulminant hepatic failure.
    Ciba Foundation symposium, 1977, Issue:55

    Topics: Ammonia; Animals; Chenodeoxycholic Acid; Cytotoxins; Dialysis; Hemoperfusion; Hepatic Encephalopathy; Hot Temperature; Humans; Lithocholic Acid; Liver; Liver Diseases; Liver Regeneration; Rabbits

1977
[Plasma bile acids fractionnation by gas-liquid chromatography : application to hepatocellular deficiency investigation (author's transl)].
    Pathologie-biologie, 1977, Volume: 25, Issue:8

    Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Cholic Acids; Chromatography, Gas; Deoxycholic Acid; Hepatitis, Viral, Human; Humans; Lithocholic Acid; Liver Cirrhosis; Liver Diseases

1977
[Fundamental studies and clinical application of "CG RIA KIT" and "SLCG RIA KIT" (author's transl)].
    Horumon to rinsho. Clinical endocrinology, 1979, Volume: 27, Issue:10

    Topics: Glycocholic Acid; Humans; Lithocholic Acid; Liver Diseases; Radioimmunoassay; Reagent Kits, Diagnostic

1979
[Clinical evaluation on serum bile acid levels in hepatobiliary disease (CG, SLCG measured by a radioimmunoassay) (author's transl)].
    Horumon to rinsho. Clinical endocrinology, 1979, Volume: 27, Issue:11

    Topics: Adult; Aged; Biliary Tract Diseases; Female; Glycocholic Acid; Humans; Lithocholic Acid; Liver Diseases; Male; Middle Aged; Radioimmunoassay; Reagent Kits, Diagnostic

1979
[Clinical significance of serum bile acid radioimmunoassay in hepatobiliary diseases--with special reference to the CG/SLCG ratio (author's transl)].
    Radioisotopes, 1979, Oct-15, Volume: 28, Issue:10

    Topics: Biliary Tract Diseases; Child, Preschool; Cholestasis; Female; Glycocholic Acid; Humans; Lithocholic Acid; Liver Diseases; Liver Neoplasms; Male; Middle Aged; Radioimmunoassay; Radionuclide Imaging

1979
[The clinical significance of radioimmunologically determined serum bile acids as a new liver function test and the development of a new intravenous sulfolithoglycocholic acid (SLGC) stimulation test].
    Acta medica Austriaca, 1979, Volume: 6, Issue:4

    Topics: Bile Acids and Salts; Biliary Tract Diseases; Dehydrocholic Acid; Diagnosis, Differential; Glycocholic Acid; Humans; Injections, Intravenous; Lithocholic Acid; Liver Diseases; Liver Function Tests; Radioimmunoassay

1979
Bile acids in liver disease associated with inflammatory bowel disease.
    Digestion, 1977, Volume: 15, Issue:6

    Topics: Adult; Aged; Bile; Bile Acids and Salts; Cholangitis; Cholic Acids; Chronic Disease; Colitis, Ulcerative; Crohn Disease; Deoxycholic Acid; Enterohepatic Circulation; Female; Humans; Lithocholic Acid; Liver Cirrhosis; Liver Diseases; Male; Middle Aged

1977
Levels of immunoreactive glycine-conjugated bile acids in health and hepatobiliary disease.
    American journal of clinical pathology, 1976, Volume: 66, Issue:5

    Topics: Alcoholism; Biliary Tract Diseases; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Deoxycholic Acid; Glycocholic Acid; Hepatitis; Humans; Lithocholic Acid; Liver Cirrhosis; Liver Diseases; Liver Neoplasms; Radioimmunoassay

1976
Proceedings: Bile acid metabolism in chronic bowel disease: Determinations in gallbladder bile, portal blood, and peripheral blood.
    Gut, 1975, Volume: 16, Issue:5

    Topics: Bile; Bile Acids and Salts; Chronic Disease; Humans; Intestinal Diseases; Lithocholic Acid; Liver Diseases

1975
Lithocholic acid accumulation.
    Hospital practice (Office ed.), 1992, Jun-15, Volume: 27, Issue:6

    Topics: Animals; Chronic Disease; Humans; Lithocholic Acid; Liver; Liver Diseases; Ursodeoxycholic Acid

1992
Drug metabolism in end-stage liver disease. In vitro activities of some phase I and phase II enzymes.
    Journal of hepatology, 1990, Volume: 11, Issue:1

    Topics: Adolescent; Adult; Aminopyrine; Child; Coumarins; Cytochrome P-450 Enzyme System; Estrone; Female; Humans; Lithocholic Acid; Liver Diseases; Liver Function Tests; Male; Middle Aged; Oxazines; Pharmaceutical Preparations; Sulfotransferases

1990
Clinical evaluation of serum 3 beta-hydroxy-5-cholenoic acid in hepatobiliary diseases.
    Gastroenterologia Japonica, 1986, Volume: 21, Issue:6

    Topics: 3-Hydroxysteroid Dehydrogenases; Bile Acids and Salts; Bilirubin; Cholestasis, Extrahepatic; Cholestasis, Intrahepatic; Cholic Acids; Chromatography, High Pressure Liquid; Glucuronidase; Glycine; Humans; Hydrolysis; Lithocholic Acid; Liver Diseases; Liver Function Tests; Pruritus; Sulfatases; Taurine

1986
Sulphated lithocholic acid conjugates in serum from children with hepatic and intestinal diseases.
    Scandinavian journal of gastroenterology, 1985, Volume: 20, Issue:10

    Topics: Adolescent; Child; Child, Preschool; Cholestasis; Glycocholic Acid; Humans; Infant; Infant, Newborn; Intestinal Diseases; Lithocholic Acid; Liver Diseases

1985
Bile acid metabolism and hepatic disease following small bowel bypass for obesity.
    The American journal of clinical nutrition, 1974, Volume: 27, Issue:12

    Topics: Adult; Bile; Bile Acids and Salts; Bilirubin; Chenodeoxycholic Acid; Cholic Acids; Deoxycholic Acid; Fatty Liver; Female; Glycine; Humans; Ileum; Jejunum; Lithocholic Acid; Liver; Liver Cirrhosis; Liver Diseases; Male; Obesity; Postoperative Complications; Protein Deficiency; Sulfuric Acids; Taurine

1974
[Bile acids in the serum of patients with extrahepatic cholestasis with chronic liver diseases].
    Zeitschrift fur Gastroenterologie, 1973, Volume: 11, Issue:4

    Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Chronic Disease; Deoxycholic Acid; Hepatic Encephalopathy; Hepatitis; Humans; Lithocholic Acid; Liver Cirrhosis; Liver Diseases

1973