Page last updated: 2024-08-21

lithocholic acid and Bile Duct Obstruction

lithocholic acid has been researched along with Bile Duct Obstruction in 106 studies

Research

Studies (106)

Timeframe	Studies, this research(%)	All Research%
pre-1990	49 (46.23)	18.7374
1990's	22 (20.75)	18.2507
2000's	6 (5.66)	29.6817
2010's	23 (21.70)	24.3611
2020's	6 (5.66)	2.80

Authors

Authors	Studies
Bi, H; Cai, C; Huang, M; Li, H; Li, X; Liang, H; Su, H; Tian, J; Wang, X; Yang, X	1
Jin, J; Li, Y; Qiu, F; Ren, J; Song, G; Tan, B; Wang, Q; Weng, F; Yan, D; Zou, B	1
Combalia, A; Dubreuil, M; Guañabens, N; Jurado, S; Monegal, A; Parés, A; Peris, P; Ruiz-Gaspà, S	1
Bi, HC; Chen, YX; Fu, KL; Guan, LH; Huang, M; Huang, QF; Li, DS; Li, X; Wan, JB; Zhang, HZ	1
Jia, R; Li, L; Ma, L; Yan, P; Yang, F	1
Gong, L; Hu, M; Liu, Z; Wang, W; Zeng, S	1
Burban, A; Guguen-Guillouzo, C; Guillouzo, A; Humbert, L; Rainteau, D; Sharanek, A	1
Fu, T; Gao, X; Kong, Y; Liu, K; Liu, Z; Ma, X; Meng, Q; Ning, C; Sun, H; Wang, C	1
Liu, W; Xu, W; Zheng, X; Zhou, Z; Zhu, S	1
Gao, X; Kong, Y; Liu, K; Liu, Z; Ma, X; Meng, Q; Ning, C; Sun, H; Sun, P; Wang, C	1
Ahmed, N; Almaramhy, HH; Alrohily, WD; Bojan, B; El-Agamy, DS; Elkablawy, MA	1
Alkhedaide, AQ; Alotaibi, SH; Ismail, TA; Nassan, MA; Shehri, ZSA	1
Aini, W; Miyagawa-Hayashino, A; Ozeki, M; Tamaki, K	1
Bi, H; Chen, Y; Fan, S; Fu, K; Gao, Y; Huang, M; Jiang, Y; Liu, C; Yao, X	1
Alvarez, L; Combalia, A; Dubreuil, M; Guañabens, N; Monegal, A; Parés, A; Peris, P; Ruiz-Gaspà, S	1
Barbier, O; Białek, A; Caron, P; Milkiewicz, P; Perreault, M; Trottier, J; Verreault, M	1
Bi, H; Chen, P; Deng, R; Fan, X; Huang, M; Wang, Y; Xu, C; Zeng, H; Zhou, X	1
Farhood, A; Fickert, P; Jaeschke, H; Li, F; Trauner, M; Woolbright, BL; Xie, Y	1
Gao, Y; Hu, D; Liang, Q; Liu, C; Ma, Z; Tan, H; Tang, X; Wang, Y; Xiao, C; Zhang, B; Zhang, X	1
Bae, S; Cho, EJ; Kang, JS; Kim, CY; Kim, YJ; Lee, HS; Lee, JH; Lee, WJ; Yoon, JH; Yu, SJ	1
Curtis, JM; Lim, DW; Mager, DR; Mazurak, VC; Mi, S; Sigalet, DL; Turner, JM; Wales, PW; Wizzard, PR; Yap, JY	1
Amano, K; Masubuchi, N; Matsuura, T; Nakano, M; Sugihara, M; Sugita, T	1
Bi, H; Chen, P; Chen, Y; Fan, X; Huang, M; Jiang, Y; Li, D; Li, X; Qin, X; Tan, H; Wang, Y; Zeng, H; Zeng, X; Zhou, Y	1
Bi, H; Chen, P; Fan, X; Gonzalez, FJ; Huang, M; Jiang, Y; Li, D; Liu, A; Liu, P; Ma, X; Xie, W; Zeng, H	1
Ko, KS; Li, TW; Lu, SC; Xia, M; Yang, H	1
Alvarez, L; Combalia, A; de Osaba, MJ; Enjuanes, A; Gonzalez, B; Guañabens, N; Martinez-Ferrer, A; Monegal, A; Parés, A; Peris, P; Ruiz-Gaspà, S	1
Ko, K; Li, J; Li, TW; Lu, SC; Oh, P; Xia, M; Yang, H	1
Aehlen, A; Ehmer, U; Erichsen, TJ; Kalthoff, S; Manns, MP; Strassburg, CP	1
Cho, JY; Gonzalez, FJ; Krausz, KW; Matsubara, T; Patterson, AD; Tanaka, N	1
Gao, Y; Li, H; Liang, QD; Ma, ZC; Tan, HL; Wang, YG; Xiao, CR; Zhang, BL; Zhou, JM	1
Coulter, S; Liddle, C; Robertson, G; Stedman, C	1
Denk, H; Fickert, P; Fuchsbichler, A; Jaeschke, H; Krause, R; Marschall, HU; Trauner, M; Wagner, M; Zatloukal, K; Zollner, G	1
Gong, H; Mangelsdorf, DJ; Michalopoulos, GK; Moschetta, A; Mu, Y; Ren, S; Saini, SP; Uppal, H; Xie, W; Zhai, Y; Zhou, J	1
Kakis, G; Phillips, MJ; Yousef, IM	1
Adcock, EW; Chari, MV; Lester, R; Little, JM; Oelberg, DG	1
Beppu, T; Otsuka, H; Seyama, Y; Takikawa, H; Yamakawa, T	1
Adcock, EW; Dubinsky, WP; Lester, R; Oelberg, DG	1
Tuchweber, B; Weber, A; Yousef, IM	1
Killenberg, PG; Kirkpatrick, RB	1
Balistreri, WF; Farrell, MK; Heubi, JE; Suchy, FJ	1
Becher, MS; Gerok, W; Kremer, B; Schmidt, K; Schölmerich, J	1
Benes, P; Bork, K; Bräuninger, W; Korting, GW; Morsches, B	1
Campbell, CB; Collins, DM; Tisch, G	1
Diallo, A; Dumont, M; Erlinger, S; Faye, B; Poirel, O	1
Sano, N; Takikawa, H; Yamanaka, M; Yamazaki, R	1
Dionne, S; Plaa, GL; Tuchweber, B; Yousef, IM	1
Ishida, T; Kaneko, JJ; Tomoda, I; Washizu, M; Washizu, T	1
Minagawa, K; Sano, N; Takikawa, H; Yamanaka, M	1
Ansari, GG; Das, JB; Uzoaru, IL	1
Claret, M; Combettes, L; Diallo, A; Dumont, M; Erlinger, S; Faye, B	1
Bernard, B; Bouvier, E; Cabrol, A; Cadranel, JF; Dorent, R; Gandjbakhch, I; Gerhardt, M; Ghoussoub, JJ; Lunel, F; Myara, A; Opolon, P; Trivin, F	1
Baxter, DJ; Elias, E; Milkiewicz, P; Mills, CO; Molloy, DP	1
Arnon, R; Budai, K; Javitt, NB; Lefkowitch, JH; Reiss, A; Yoshimura, T	1
Evans, RM; Nelson, MC; Ong, ES; Radominska-Pandya, A; Shi, Y; Simon, CM; Waxman, DJ; Xie, W	1
Bock, HH; Lammert, F	1
DenBesten, L; Gurll, N	1
Ilson, RG; Kay, RM; Paloheimo, JE; Petrunka, CN; Strasberg, SM	1
Kakis, G; Yousef, IM	1
Paumgartner, G; Reichen, J	1
Stiehl, A	2
Hofmann, AF; van Berge Henegouwen, GP	1
Amuro, Y; Endo, T; Higashino, K; Uchida, K; Yamamura, Y	1
Hyon, U; Yoshida, M	1
Ibayashi, H; Ichiya, Y; Kamoi, I; Koga, S; Matsuura, K; Nishitani, H; Oshiumi, Y	1
Bonvicini, F; Borel, GA; Gardiol, D; Gautier, A	1
Drew, R; Priestly, BG	1
Javitt, NB; Mayr, W; Miyai, K; Richardson, AL	1
Campbell, CB; McGuffie, C; Powell, LW; Weedon, AP	1
Boyer, JL; Layden, TJ	2
Bloomer, JR; Ghent, CN; Klatskin, G	1
Demers, LM; Hepner, GW	1
Berndt, WO; Cooke, WJ; Mudge, GH	1
Mayr, WW; Miyal, K; Richardson, AL	1
Sturdevant, RA	1
Raymond, P; Tuchweber, B; Vu, DD; Yousef, IM	1
Hardonk, MJ; Kuipers, F; van der Meer, R; Vonk, RJ	1
Plaa, GL; Tuchweber, B; Vu, DD; Yousef, IM	2
Tuchweber, B; Villalon, L; Yousef, IM	1
Belli, DC; Fournier, LA; Giguère, R; Roy, CC; Tuchweber, B; Yousef, IM	1
Kasama, T; Ohki, H; Sano, N; Takikawa, H; Yamanaka, M	1
Bentor, R; Pinus, H; Zimber, A; Zusman, I	1
Baumgartner, U; Gerok, W; Kitamura, S; Miyai, K; Schölmerich, J	1
Couture, J; Dahlström-King, L; du Souich, P; Plaa, GL	1
Bohdan, PM; Heuman, DM; Hylemon, PB; Sirica, AE; Vlahcevic, ZR	1
Baumgartner, U; Gerok, W; Miyai, K; Schölmerich, J	1
Fujii, T; Hirano, Y; Nagai, M; Nakayama, F; Yanagisawa, J	1
Dahlström-King, L; Plaa, GL	1
Chałasinska, B; Galinsky, RE	1
Kuipers, F; van der Meer, R; Vonk, RJ	1
Gauvin, M; Kugelmass, R; Morazain, R; Roy, CC; Tuchweber, B; Weber, AM; Yousef, IM	1
Baumgartner, U; Hardison, WG; Miyai, K	1
Barnwell, SG; Tuchweber, B; Yousef, IM	1
Cohen, BI; May-Donath, P; McSherry, CK; Mosbach, EH; Une, M	1
Ayotte, P; Plaa, GL	1
Bijleveld, CM; Fernandes, J; Kneepkens, CM; Kuipers, F; van Zanten, A; Vonk, RJ	1
King, JE; Schoenfield, LJ	1
Murphy, GM; Signer, E	1
Back, P	2
Russell, RI	1
Erb, W; Schreiber, J; Walczak, M	1
Liersch, M; Stiehl, A	1
Bolton, CH; James, JA; Read, AE	1

Reviews

6 review(s) available for lithocholic acid and Bile Duct Obstruction

Article	Year
Animal models of human cholesterol gallstone disease: a review. Laboratory animal science, 1978, Volume: 28, Issue:4 Topics: Animals; Cats; Cholelithiasis; Cholestasis; Cholesterol, Dietary; Cholestyramine Resin; Cricetinae; Disease Models, Animal; Dogs; Female; Guinea Pigs; Haplorhini; Humans; Lithocholic Acid; Male; Rabbits; Rats; Rodentia; Saimiri; Sciuridae	1978
Disturbances of bile acid metabolism in cholestasis. Clinics in gastroenterology, 1977, Volume: 6, Issue:1 Topics: Bile Acids and Salts; Bile Ducts; Cholestasis; Cholestyramine Resin; Deoxycholic Acid; Disease Models, Animal; Female; Glucuronates; Hepatitis; Humans; Ligation; Lithocholic Acid; Liver; Liver Cirrhosis; Male; Phenobarbital; Pregnancy; Pregnancy Complications; Sterols; Sulfates	1977
Clinical aspects of disturbances in the enterohepatic circulation of bile acids in man: the cholanopathies. The Netherlands journal of medicine, 1978, Volume: 21, Issue:6 Topics: Bile Acids and Salts; Biliary Tract Diseases; Celiac Disease; Chenodeoxycholic Acid; Cholelithiasis; Cholestasis; Cholic Acids; Colonic Neoplasms; Deoxycholic Acid; Diarrhea; Humans; Intestinal Diseases; Intestine, Small; Lipid Metabolism; Lithocholic Acid; Liver; Liver Circulation; Malabsorption Syndromes; Portal System	1978
Lithocholic acid, cholestasis, and liver disease. Mayo Clinic proceedings, 1972, Volume: 47, Issue:10 Topics: Animals; Bile; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Cholestasis; Disease Models, Animal; Humans; Hydroxylation; Lithocholic Acid; Liver; Liver Diseases; Solubility; Species Specificity	1972
Bile acid metabolism in infants and children. Gut, 1974, Volume: 15, Issue:2 Topics: Bile; Bile Acids and Salts; Biological Transport, Active; Chenodeoxycholic Acid; Child; Child, Preschool; Cholestasis; Cholesterol; Cholic Acids; Deoxycholic Acid; Humans; Infant; Infant Nutrition Disorders; Infant, Newborn; Lithocholic Acid; Liver; Liver Diseases; Malabsorption Syndromes; Surface Properties	1974
Sulfation of bile salts: a new metabolic pathway. Digestion, 1974, Volume: 11, Issue:5-6 Topics: Animals; Bile; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Deoxycholic Acid; Humans; Lithocholic Acid; Liver; Rats; Sulfates	1974

Other Studies

100 other study(ies) available for lithocholic acid and Bile Duct Obstruction

Article	Year
Schisandrol B protects against cholestatic liver injury by inhibiting pyroptosis through pregnane X receptor. Biochemical pharmacology, 2022, Volume: 204 Topics: Caspase 3; Cholestasis; Cyclooctanes; Dioxoles; Humans; Inflammasomes; Lignans; Lithocholic Acid; Liver; Luciferases; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidoreductases; Pregnane X Receptor; Pyroptosis	2022
15,16-dihydrotanshinone I in Danshen ethanol extract aggravated cholestasis by inhibiting Cyp3a11 mediated bile acids hydroxylation. Toxicology letters, 2023, Mar-15, Volume: 377 Topics: Animals; Bile Acids and Salts; Cholestasis; Cytochrome P-450 CYP3A; Ethanol; Hydroxylation; Lithocholic Acid; Membrane Proteins; Mice; Salvia miltiorrhiza	2023
Bile acids and bilirubin effects on osteoblastic gene profile. Implications in the pathogenesis of osteoporosis in liver diseases. Gene, 2020, Jan-30, Volume: 725 Topics: Apoptosis; Bile Acids and Salts; Bilirubin; Cell Line, Tumor; Cholestasis; Down-Regulation; Genetic Profile; Humans; Lithocholic Acid; Liver; Liver Diseases; Osteoblasts; Osteoporosis; Osteosarcoma; Up-Regulation; Ursodeoxycholic Acid	2020
Targeted bile acids and gut microbiome profiles reveal the hepato-protective effect of WZ tablet (Schisandra sphenanthera extract) against LCA-induced cholestasis. Chinese journal of natural medicines, 2020, Volume: 18, Issue:3 Topics: Animals; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Cholestasis; Drugs, Chinese Herbal; Gastrointestinal Microbiome; Lithocholic Acid; Male; Metabolome; Mice; Mice, Inbred C57BL; Plant Extracts; Schisandra; Tablets	2020
Velvet antler polypeptide prevents the disruption of hepatic tight junctions Food & function, 2020, Nov-18, Volume: 11, Issue:11 Topics: Administration, Oral; Animals; Antlers; Cell Line, Tumor; Cholestasis; Deer; Hepatocytes; Humans; Lithocholic Acid; Liver; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Peptides; Tight Junctions	2020
The Function of Multidrug Resistance-associated Protein 3 in the Transport of Bile Acids under Normal Physiological and Lithocholic Acid-induced Cholestasis Conditions. Current drug metabolism, 2021, Volume: 22, Issue:5 Topics: Animals; Bile Acids and Salts; Cholestasis; Lithocholic Acid; Liver; Mice; Mice, Inbred C57BL; Mice, Knockout; Multidrug Resistance-Associated Proteins	2021
Progressive and Preferential Cellular Accumulation of Hydrophobic Bile Acids Induced by Cholestatic Drugs Is Associated with Inhibition of Their Amidation and Sulfation. Drug metabolism and disposition: the biological fate of chemicals, 2017, Volume: 45, Issue:12 Topics: Amides; Bile Acids and Salts; Cell Line; Chenodeoxycholic Acid; Cholestasis; Deoxycholic Acid; Humans; Lithocholic Acid; Liver; Organic Anion Transporters, Sodium-Dependent; Sulfates; Symporters; Taurocholic Acid	2017
Computational discovery and experimental verification of farnesoid X receptor agonist auraptene to protect against cholestatic liver injury. Biochemical pharmacology, 2017, 12-15, Volume: 146 Topics: Animals; Cell Survival; Cholestasis; Computational Biology; Coumarins; Drug Discovery; Hep G2 Cells; Humans; Lithocholic Acid; Male; Mice; Mice, Inbred C57BL; Models, Molecular; Protein Conformation; Receptors, Cytoplasmic and Nuclear	2017
Glycyrrhetic Acid Derivative TY501 Protects Against Lithocholic Acid-Induced Cholestasis. Drug research, 2018, Volume: 68, Issue:7 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; Cell Line, Tumor; Cholestasis; Down-Regulation; Glycyrrhetinic Acid; Hep G2 Cells; Humans; Lithocholic Acid; Liver; Male; Mice; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Organic Anion Transporters, Sodium-Dependent; Protective Agents; Symporters; Up-Regulation	2018
Protective effects of yangonin from an edible botanical Kava against lithocholic acid-induced cholestasis and hepatotoxicity. European journal of pharmacology, 2018, Apr-05, Volume: 824 Topics: Animals; Cell Line; Cholestasis; Cytoprotection; Hepatocytes; Homeostasis; Kava; Lithocholic Acid; Liver; Male; Mice; Mice, Inbred C57BL; Pyrones; Receptors, Cytoplasmic and Nuclear	2018
Anti-Inflammatory Effects of Vardenafil Against Cholestatic Liver Damage in Mice: a Mechanistic Study. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 47, Issue:2 Topics: Alkaline Phosphatase; Animals; Anti-Inflammatory Agents; Antioxidants; Caspase 1; Cholestasis; Cytokines; Glutamate-Cysteine Ligase; Glutathione; Lithocholic Acid; Liver; Liver Diseases; Male; Mice; NF-E2-Related Factor 2; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Transaminases; Vardenafil Dihydrochloride	2018
Preventive effect of artemisinin extract against cholestasis induced via lithocholic acid exposure. Bioscience reports, 2018, 12-21, Volume: 38, Issue:6 Topics: Alanine Transaminase; Animals; Artemisinins; Aspartate Aminotransferases; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Cholestasis; Gene Expression Regulation; Hepatocytes; Humans; Lithocholic Acid; Liver; Liver-Specific Organic Anion Transporter 1; Mice; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; RNA, Messenger	2018
Prevention of Cell Growth by Suppression of Villin Expression in Lithocholic Acid-Stimulated HepG2 Cells. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 2019, Volume: 67, Issue:2 Topics: Bile Canaliculi; Cell Proliferation; Cholestasis; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Lithocholic Acid; Microfilament Proteins	2019
Lignans from Schisandra sphenanthera protect against lithocholic acid-induced cholestasis by pregnane X receptor activation in mice. Journal of ethnopharmacology, 2019, Dec-05, Volume: 245 Topics: Animals; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Cholestasis; Feces; HEK293 Cells; Hep G2 Cells; Humans; Intestinal Mucosa; Lignans; Lithocholic Acid; Liver; Male; Mice, Inbred C57BL; Pregnane X Receptor; Protective Agents; Schisandra	2019
Ursodeoxycholic acid increases differentiation and mineralization and neutralizes the damaging effects of bilirubin on osteoblastic cells. Liver international : official journal of the International Association for the Study of the Liver, 2013, Volume: 33, Issue:7 Topics: Bilirubin; Calcification, Physiologic; Cell Differentiation; Cell Line, Tumor; Cell Survival; Cholestasis; Humans; Jaundice; Lithocholic Acid; Osteoblasts; Osteoporosis; Statistics, Nonparametric; Ursodeoxycholic Acid	2013
Role of glucuronidation for hepatic detoxification and urinary elimination of toxic bile acids during biliary obstruction. PloS one, 2013, Volume: 8, Issue:11 Topics: Apoptosis; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Deoxycholic Acid; Female; Hep G2 Cells; Humans; Lithocholic Acid; Liver; Male	2013
Low dose of oleanolic acid protects against lithocholic acid-induced cholestasis in mice: potential involvement of nuclear factor-E2-related factor 2-mediated upregulation of multidrug resistance-associated proteins. Drug metabolism and disposition: the biological fate of chemicals, 2014, Volume: 42, Issue:5 Topics: Animals; Chemical and Drug Induced Liver Injury; Cholestasis; Dose-Response Relationship, Drug; Gene Expression; Hep G2 Cells; Hepatocytes; Humans; Lithocholic Acid; Liver Function Tests; Male; Mice; Mice, Inbred C57BL; Multidrug Resistance-Associated Proteins; NF-E2-Related Factor 2; Oleanolic Acid; Primary Cell Culture; Up-Regulation	2014
Lithocholic acid feeding results in direct hepato-toxicity independent of neutrophil function in mice. Toxicology letters, 2014, Jul-03, Volume: 228, Issue:1 Topics: Animals; Bile; Bile Acids and Salts; Blotting, Western; Caspases; Chemical and Drug Induced Liver Injury; Cholestasis; Diet; Hepatocytes; Immunohistochemistry; Inflammation; Lithocholic Acid; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidase 2; NADPH Oxidases; Necrosis; Neutrophils; Real-Time Polymerase Chain Reaction; Receptors, Immunologic; Up-Regulation	2014
Tanshinone IIA exerts protective effects in a LCA-induced cholestatic liver model associated with participation of pregnane X receptor. Journal of ethnopharmacology, 2015, Apr-22, Volume: 164 Topics: Abietanes; Animals; Cholestasis; Cytochrome P-450 CYP3A; Hep G2 Cells; Humans; Lithocholic Acid; Male; Mice, Inbred BALB C; Phytotherapy; Pregnane X Receptor; Protective Agents; Receptors, Steroid; RNA, Messenger	2015
Hepatoprotective effect of vitamin C on lithocholic acid-induced cholestatic liver injury in Gulo(-/-) mice. European journal of pharmacology, 2015, Sep-05, Volume: 762 Topics: Animals; Ascorbic Acid; Cell Line; Cholestasis; Cytoprotection; Hepatocytes; Humans; Lithocholic Acid; Liver; Liver Cirrhosis; Male; Mice; Mice, Knockout; Reactive Oxygen Species	2015
Glucagon-Like Peptide-2 Alters Bile Acid Metabolism in Parenteral Nutrition--Associated Liver Disease. JPEN. Journal of parenteral and enteral nutrition, 2016, Volume: 40, Issue:1 Topics: Animals; Animals, Newborn; Bile Acids and Salts; Cholestasis; Cholesterol 7-alpha-Hydroxylase; Disease Models, Animal; Gene Expression Regulation; Glucagon-Like Peptide 2; Lithocholic Acid; Liver Diseases; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Parenteral Nutrition; Swine; Tandem Mass Spectrometry; Transcriptome	2016
Oxidative stress markers, secondary bile acids and sulfated bile acids classify the clinical liver injury type: Promising diagnostic biomarkers for cholestasis. Chemico-biological interactions, 2016, Aug-05, Volume: 255 Topics: Aged; Bile Acids and Salts; Biomarkers; Cholestasis; Collagen Type IV; Deoxycholic Acid; Female; Humans; Hyaluronic Acid; Lithocholic Acid; Liver Cirrhosis; Liver Diseases; Male; Middle Aged; Oxidative Stress; Reactive Oxygen Species; Sulfates	2016
Hepatoprotective Effects of Schisandra sphenanthera Extract against Lithocholic Acid-Induced Cholestasis in Male Mice Are Associated with Activation of the Pregnane X Receptor Pathway and Promotion of Liver Regeneration. Drug metabolism and disposition: the biological fate of chemicals, 2016, Volume: 44, Issue:3 Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Cholestasis; Cytochrome P-450 CYP3A; Drugs, Chinese Herbal; Glucuronosyltransferase; Lignans; Lithocholic Acid; Liver; Liver Regeneration; Male; Mice; Mice, Inbred C57BL; Plant Extracts; Pregnane X Receptor; Protective Agents; Receptors, Steroid; Schisandra; Signal Transduction	2016
Schisandrol B protects against cholestatic liver injury through pregnane X receptors. British journal of pharmacology, 2017, Volume: 174, Issue:8 Topics: Animals; Cholestasis; Cyclooctanes; Dioxoles; Lignans; Lithocholic Acid; Liver; Male; Mice; Mice, Inbred C57BL; Pregnane X Receptor; Receptors, Steroid; Signal Transduction	2017
Switch from Mnt-Max to Myc-Max induces p53 and cyclin D1 expression and apoptosis during cholestasis in mouse and human hepatocytes. Hepatology (Baltimore, Md.), 2009, Volume: 49, Issue:3 Topics: Animals; Apoptosis; Base Sequence; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Cell Line, Tumor; Cells, Cultured; Cholestasis; Cyclin D1; Disease Models, Animal; Hepatocytes; Humans; Ligation; Lithocholic Acid; Male; Mice; Mice, Inbred C57BL; Proto-Oncogene Proteins c-myc; Repressor Proteins; Signal Transduction; Tumor Suppressor Protein p53	2009
Lithocholic acid downregulates vitamin D effects in human osteoblasts. European journal of clinical investigation, 2010, Volume: 40, Issue:1 Topics: Cell Survival; Cells, Cultured; Cholestasis; Down-Regulation; Humans; Lithocholic Acid; Osteoblasts; Osteocalcin; Osteoporosis; Osteoprotegerin; Promoter Regions, Genetic; RANK Ligand; RNA; Steroid Hydroxylases; Transfection; Vitamin D; Vitamin D3 24-Hydroxylase	2010
Induction of avian musculoaponeurotic fibrosarcoma proteins by toxic bile acid inhibits expression of glutathione synthetic enzymes and contributes to cholestatic liver injury in mice. Hepatology (Baltimore, Md.), 2010, Volume: 51, Issue:4 Topics: Animals; Cell Line, Tumor; Cholestasis; Glutamate-Cysteine Ligase; Glutathione; Humans; Lithocholic Acid; MafG Transcription Factor; MafK Transcription Factor; Male; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Promoter Regions, Genetic; Repressor Proteins; Response Elements; S-Adenosylmethionine; Ursodeoxycholic Acid	2010
Regulation of the human bile acid UDP-glucuronosyltransferase 1A3 by the farnesoid X receptor and bile acids. Journal of hepatology, 2010, Volume: 52, Issue:4 Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Gene Expression; Genes, Reporter; Genetic Variation; Glucuronosyltransferase; Hep G2 Cells; Humans; Lithocholic Acid; Luciferases; Mutagenesis, Site-Directed; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; Transcriptional Activation; Ursodeoxycholic Acid; Xenobiotics	2010
Lithocholic acid disrupts phospholipid and sphingolipid homeostasis leading to cholestasis in mice. Hepatology (Baltimore, Md.), 2011, Volume: 53, Issue:4 Topics: 1-Acylglycerophosphocholine O-Acyltransferase; Animals; Ceramides; Cholestasis; Female; Homeostasis; Lithocholic Acid; Lysophosphatidylcholines; Metabolome; Mice; Mice, Inbred C57BL; Phospholipids; RNA, Messenger; Sphingolipids; Sphingomyelin Phosphodiesterase; Sphingomyelins; Transforming Growth Factor beta	2011
Pregnane X receptor mediated-transcription regulation of CYP3A by glycyrrhizin: a possible mechanism for its hepatoprotective property against lithocholic acid-induced injury. Chemico-biological interactions, 2012, Oct-25, Volume: 200, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cholestasis; Cholesterol 7-alpha-Hydroxylase; Cytochrome P-450 CYP3A; Cytoprotection; Dose-Response Relationship, Drug; Enzyme Induction; Gene Expression Regulation; Glycyrrhizic Acid; Hep G2 Cells; Humans; Lithocholic Acid; Liver; Male; Mice; Pregnane X Receptor; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Time Factors; Transcription, Genetic	2012
Feed-forward regulation of bile acid detoxification by CYP3A4: studies in humanized transgenic mice. The Journal of biological chemistry, 2004, Mar-19, Volume: 279, Issue:12 Topics: Animals; Base Sequence; Cholestasis; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; DNA Primers; Humans; Inactivation, Metabolic; Lac Operon; Lithocholic Acid; Liver; Male; Mice; Mice, Transgenic; Organ Size	2004
Lithocholic acid feeding induces segmental bile duct obstruction and destructive cholangitis in mice. The American journal of pathology, 2006, Volume: 168, Issue:2 Topics: Animals; Bile Acids and Salts; Biliary Tract Diseases; Chemical and Drug Induced Liver Injury; Cholangitis; Cholestasis; Detergents; Diet; Fibrosis; Fluorescence; Lithocholic Acid; Liver; Liver Diseases; Male; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Organic Anion Transporters; Organic Anion Transporters, Sodium-Dependent; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfotransferases; Symporters	2006
Activation of LXRs prevents bile acid toxicity and cholestasis in female mice. Hepatology (Baltimore, Md.), 2007, Volume: 45, Issue:2 Topics: Animals; Bile Acids and Salts; Cholestasis; Cholesterol; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 7; DNA-Binding Proteins; Female; Homeostasis; Lithocholic Acid; Liver X Receptors; Mice; Mice, Transgenic; Orphan Nuclear Receptors; Receptors, Cytoplasmic and Nuclear; Sex Characteristics; Steroid Hydroxylases; Sulfotransferases	2007
The respective roles of membrane cholesterol and of sodium potassium adenosine triphosphatase in the pathogenesis of lithocholate-induced cholestasis. Laboratory investigation; a journal of technical methods and pathology, 1980, Volume: 43, Issue:1 Topics: Animals; Bile; Bile Ducts, Intrahepatic; Cell Membrane; Cholestasis; Cholesterol; Lipids; Lithocholic Acid; Liver; Male; Membrane Lipids; Microscopy, Electron; Pentobarbital; Rats; Sodium-Potassium-Exchanging ATPase	1980
Lithocholate glucuronide is a cholestatic agent. The Journal of clinical investigation, 1984, Volume: 73, Issue:6 Topics: Animals; Bile; Bile Acids and Salts; Biliary Fistula; Cholestasis; Chromatography, Gas; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Glucuronates; Kinetics; Lithocholic Acid; Male; Rats; Rats, Inbred Strains; Tritium	1984
Serum concentrations of bile acid glucuronides in hepatobiliary diseases. Digestion, 1983, Volume: 27, Issue:4 Topics: Adult; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Female; Gas Chromatography-Mass Spectrometry; Glucuronates; Hepatitis; Humans; Lithocholic Acid; Liver Cirrhosis; Male	1983
Calcium binding by lithocholic acid derivatives. The American journal of physiology, 1984, Volume: 247, Issue:1 Pt 1 Topics: Animals; Bile Acids and Salts; Calcium; Cholestasis; Lithocholic Acid; Rats; Spectrophotometry	1984
Prevention of lithocholate--induced cholestasis by cycloheximide, an inhibitor of protein synthesis. Life sciences, 1983, Jul-04, Volume: 33, Issue:1 Topics: Animals; Bile; Bile Acids and Salts; Cell Membrane; Cholestasis; Cholesterol; Cycloheximide; Lithocholic Acid; Liver; Male; Microscopy, Electron; Rats; Rats, Inbred Strains	1983
Effects of ethinylestradiol on enzymes catalyzing bile acid conjugation and sulfation. Journal of lipid research, 1980, Volume: 21, Issue:7 Topics: Acyltransferases; Animals; Bile Acids and Salts; Cholestasis; Cholic Acids; Coenzyme A Ligases; Dose-Response Relationship, Drug; Ethinyl Estradiol; Glycocholic Acid; Lithocholic Acid; Liver; Male; Organ Size; Propylene Glycols; Rats; Sulfotransferases; Sulfurtransferases; Time Factors	1980
Pathologic versus physiologic cholestasis: elevated serum concentration of a secondary bile acid in the presence of hepatobiliary disease. The Journal of pediatrics, 1981, Volume: 98, Issue:3 Topics: Biliary Tract Diseases; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Humans; Infant; Infant, Newborn; Lithocholic Acid; Liver Diseases; Sulfates	1981
[Different effect of taurolithocholate and chenodeoxycholate on structure and function of isolated hepatocytes (author's transl)]. Klinische Wochenschrift, 1981, Jun-15, Volume: 59, Issue:12 Topics: Animals; Aspartate Aminotransferases; Cell Membrane; Chenodeoxycholic Acid; Cholestasis; Dose-Response Relationship, Drug; Glucagon; L-Lactate Dehydrogenase; Lithocholic Acid; Liver; Microscopy, Electron; Microscopy, Electron, Scanning; Rats; Taurolithocholic Acid; Uric Acid	1981
[Pruritus and bile acids. Determination of sulfalithoglycocholate and glycocholate in suction blister fluid and in serum (author's transl)]. Archives of dermatological research, 1981, Volume: 270, Issue:4 Topics: Adult; Aged; Bile Acids and Salts; Blister; Cholestasis; Exudates and Transudates; Female; Glycocholic Acid; Humans; Lithocholic Acid; Male; Middle Aged; Pruritus	1981
Evaluation of enzymic and radioimmunoassay methods for measuring serum bile acids. Pathology, 1980, Volume: 12, Issue:4 Topics: Bile Acids and Salts; Cholestasis; Chromatography, Gas; Eating; Fasting; Glycocholic Acid; Humans; Lithocholic Acid; Liver Cirrhosis; Radioimmunoassay	1980
[Toxicity of cholestatic bile acids on intrahepatic biliary cells of the rat]. Dakar medical, 1994, Volume: 39, Issue:1 Topics: Animals; Bile Acids and Salts; Bile Ducts, Intrahepatic; Cell Death; Cholestasis; gamma-Glutamyltransferase; Keratins; Ligation; Lithocholic Acid; Rats; Rats, Sprague-Dawley; Taurolithocholic Acid	1994
Colchicine inhibits lithocholate-3-O-glucuronide-induced cholestasis in rats. Journal of hepatology, 1995, Volume: 22, Issue:1 Topics: Animals; Bile; Cholestasis; Colchicine; Glucuronates; Lithocholic Acid; Male; Rats; Rats, Sprague-Dawley; Taurochenodeoxycholic Acid; Taurocholic Acid; Vinblastine	1995
Phase I and phase II metabolism of lithocholic acid in hepatic acinar zone 3 necrosis. Evaluation in rats by combined radiochromatography and gas-liquid chromatography-mass spectrometry. Biochemical pharmacology, 1994, Sep-15, Volume: 48, Issue:6 Topics: Animals; Bile; Bile Acids and Salts; Bromobenzenes; Carbon Radioisotopes; Cholestasis; Chromatography, Thin Layer; Gas Chromatography-Mass Spectrometry; Glucuronates; Lithocholic Acid; Liver Diseases; Male; Necrosis; Rats; Rats, Sprague-Dawley	1994
Changes in bile acid composition of serum and gallbladder bile in bile duct ligated dogs. The Journal of veterinary medical science, 1994, Volume: 56, Issue:2 Topics: Animals; Bile Acids and Salts; Bile Ducts; Chenodeoxycholic Acid; Cholestasis; Cholic Acid; Cholic Acids; Dogs; Gallbladder; Lithocholic Acid; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid; Time Factors	1994
Lithocholate-3-O-glucuronide-induced cholestasis. A study with congenital hyperbilirubinemic rats and effects of ursodeoxycholate conjugates. Digestive diseases and sciences, 1993, Volume: 38, Issue:8 Topics: Animals; Bile; Cholestasis; Glucuronates; Hyperbilirubinemia, Hereditary; Lithocholic Acid; Liver; Male; Rats; Rats, Sprague-Dawley; Taurochenodeoxycholic Acid; Ursodeoxycholic Acid	1993
Biliary lithocholate and cholestasis during and after total parenteral nutrition: an experimental study. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1995, Volume: 210, Issue:3 Topics: Animals; Bile; Bile Acids and Salts; Cholestasis; Enteral Nutrition; Female; Indicators and Reagents; Lithocholic Acid; Liver; Parenteral Nutrition, Total; Rabbits; Sulfobromophthalein	1995
[Effects of cholestatic bile acids on cytosolic calcium in isolated intrahepatic biliary cells]. Dakar medical, 1994, Volume: 39, Issue:2 Topics: Animals; Bile Acids and Salts; Bile Ducts, Intrahepatic; Calcium; Cholestasis; Cytosol; Lithocholic Acid; Rats; Taurolithocholic Acid	1994
Cyclosporin A-mediated cholestasis in patients with chronic hepatitis after heart transplantation. European journal of gastroenterology & hepatology, 1996, Volume: 8, Issue:3 Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Bile Acids and Salts; Bilirubin; Chenodeoxycholic Acid; Cholestasis; Cholic Acid; Cholic Acids; Chromatography, High Pressure Liquid; Cyclosporine; Fasting; Female; Glycocholic Acid; Heart Transplantation; Hepatitis, Chronic; Humans; Immunosuppressive Agents; Lithocholic Acid; Male; Middle Aged; Spectrophotometry, Ultraviolet; Taurocholic Acid; Ursodeoxycholic Acid	1996
Synthesis, physical and biological properties of lithocholyl-lysyl-fluorescein: a fluorescent monohydroxy bile salt analogue with cholestatic properties. Biochimica et biophysica acta, 1997, Oct-20, Volume: 1336, Issue:3 Topics: Animals; Bile; Bile Acids and Salts; Cholestasis; Fluoresceins; Glucuronates; Indicators and Reagents; Lithocholic Acid; Lysine; Male; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Rats; Rats, Wistar; Solubility	1997
Cholesterol 7-hydroxylase knockout mouse: a model for monohydroxy bile acid-related neonatal cholestasis. Gastroenterology, 1998, Volume: 115, Issue:5 Topics: Animals; Animals, Newborn; Bile Acids and Salts; Bile Canaliculi; Cholestasis; Cholic Acids; Chromatography, Thin Layer; Cytochrome P-450 Enzyme System; Disease Models, Animal; Gas Chromatography-Mass Spectrometry; Hydroxycholesterols; Lithocholic Acid; Liver; Mice; Mice, Mutant Strains; Reference Values; RNA, Messenger; Spleen; Steroid 12-alpha-Hydroxylase	1998
An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids. Proceedings of the National Academy of Sciences of the United States of America, 2001, Mar-13, Volume: 98, Issue:6 Topics: Animals; Aryl Hydrocarbon Hydroxylases; Bile Acids and Salts; Cell Line; Cell Nucleus; Chlorocebus aethiops; Cholestasis; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzyme Induction; Humans; Lithocholic Acid; Mice; Mice, Knockout; Oxidoreductases, N-Demethylating; Pregnane X Receptor; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Substrate Specificity	2001
Nuclear xeno-sensors as receptors for cholestatic bile acids: the second line of defense. Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1 Topics: Animals; Aryl Hydrocarbon Hydroxylases; Bile Acids and Salts; Cholestasis; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Hydroxylation; Lithocholic Acid; Liver Diseases; Mice; Mice, Knockout; Mice, Transgenic; Oxidoreductases, N-Demethylating; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid	2002
Taurolithocholic acid and chlorpromazine cholestasis in the rhesus monkey. Canadian journal of physiology and pharmacology, 1979, Volume: 57, Issue:10 Topics: Animals; Cell Membrane Permeability; Chlorpromazine; Cholestasis; Dose-Response Relationship, Drug; Erythritol; Female; Haplorhini; Lithocholic Acid; Macaca mulatta; Permeability; Taurolithocholic Acid; Time Factors	1979
Pathogenesis of lithocholate- and taurolithocholate-induced intrahepatic cholestasis in rats. Gastroenterology, 1978, Volume: 75, Issue:4 Topics: Adenosine Triphosphatases; Animals; Bile; Bile Ducts, Intrahepatic; Cell Membrane; Cholestasis; Cholesterol; Disease Models, Animal; Lithocholic Acid; Liver; Male; Membrane Proteins; Peptides; Phospholipids; Rats; Secretory Rate; Sodium-Potassium-Exchanging ATPase; Taurolithocholic Acid	1978
Inhibition of hepatic Na +, K + -adenosinetriphosphatase in taurolithocholate-induced cholestasis in the rat. Experientia, 1979, Sep-15, Volume: 35, Issue:9 Topics: Animals; Bile; Bile Acids and Salts; Cell Membrane; Cholestasis; Kinetics; Lithocholic Acid; Liver; Male; Rats; Sodium-Potassium-Exchanging ATPase; Taurolithocholic Acid	1979
Bile acid metabolism in benign recurrent intrahepatic cholestasis. Comparative studies on the icteric and anicteric phases of a single case. Gastroenterology, 1979, Volume: 76, Issue:5 Pt 1 Topics: Adult; Bile; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Deoxycholic Acid; Feces; Humans; Lithocholic Acid; Male; Recurrence	1979
Bile acid secretion following release of biliary obstruction. Gastroenterologia Japonica, 1979, Volume: 14, Issue:6 Topics: Bile Acids and Salts; Cholecystectomy; Cholelithiasis; Cholestasis; Common Bile Duct; Deoxycholic Acid; Gallstones; Humans; Lithocholic Acid	1979
[Clinical significance of serum bile acid radioimmunoassay in hepatobiliary diseases--with special reference to the CG/SLCG ratio (author's transl)]. Radioisotopes, 1979, Oct-15, Volume: 28, Issue:10 Topics: Biliary Tract Diseases; Child, Preschool; Cholestasis; Female; Glycocholic Acid; Humans; Lithocholic Acid; Liver Diseases; Liver Neoplasms; Male; Middle Aged; Radioimmunoassay; Radionuclide Imaging	1979
Cholesterol in acute cholestasis induced by taurolithocholic acid. A cytochemical study in transmission and scanning electron microscopy. Laboratory investigation; a journal of technical methods and pathology, 1978, Volume: 38, Issue:4 Topics: Animals; Bile Ducts, Intrahepatic; Cell Membrane; Cholestasis; Cholesterol; Histocytochemistry; Lithocholic Acid; Liver; Male; Rats; Taurolithocholic Acid	1978
Failure of hypoactive hypertrophic smooth endoplasmic reticulum to produce cholestasis in rats. Toxicology and applied pharmacology, 1978, Volume: 45, Issue:1 Topics: Animals; Cholestasis; Cobalt; Endoplasmic Reticulum; Hypertrophy; Lithocholic Acid; Liver Function Tests; Male; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Rats	1978
Subcellular pathology of rat liver in cholestasis and choleresis induced by bile salts. 1. Effects of lithocholic, 3beta-hydroxy-5-cholenoic, cholic, and dehydrocholic acids. Laboratory investigation; a journal of technical methods and pathology, 1977, Volume: 36, Issue:3 Topics: Animals; Bile; Bile Acids and Salts; Bile Ducts, Intrahepatic; Cell Membrane; Cholagogues and Choleretics; Cholestasis; Cholic Acids; Dehydrocholic Acid; Dilatation, Pathologic; Lithocholic Acid; Liver; Male; Microscopy, Electron; Microscopy, Electron, Scanning; Rats; Secretory Rate	1977
Cholestatic liver disease associated with diphenylhydantoin therapy. Possible pathogenic importance of altered bile salt metabolism. The American journal of digestive diseases, 1977, Volume: 22, Issue:3 Topics: Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Child; Cholestasis; Humans; Hyperlipidemias; Jaundice; Lipoproteins; Lithocholic Acid; Liver; Male; Phenytoin	1977
Taurolithocholate-induced cholestasis: taurocholate but not dehydrocholate, reverses cholestasis and bile canalicular membrane injury. Gastroenterology, 1977, Volume: 73, Issue:1 Topics: Animals; Bile; Chemical and Drug Induced Liver Injury; Cholestasis; Cholic Acids; Dehydrocholic Acid; Disease Models, Animal; Erythritol; Inulin; Lithocholic Acid; Liver; Liver Function Tests; Male; Microscopy, Electron, Scanning; Rats; Secretory Rate; Taurocholic Acid	1977
Elevations in skin tissue levels of bile acids in human cholestasis: relation to serum levels and topruritus. Gastroenterology, 1977, Volume: 73, Issue:5 Topics: Adult; Aged; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Deoxycholic Acid; Female; Humans; Lithocholic Acid; Male; Middle Aged; Pruritus; Skin	1977
Levels of immunoreactive glycine-conjugated bile acids in health and hepatobiliary disease. American journal of clinical pathology, 1976, Volume: 66, Issue:5 Topics: Alcoholism; Biliary Tract Diseases; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Deoxycholic Acid; Glycocholic Acid; Hepatitis; Humans; Lithocholic Acid; Liver Cirrhosis; Liver Diseases; Liver Neoplasms; Radioimmunoassay	1976
Effect of biliary stasis and hepatotoxins on the excretion of iopanoate in the rat. The Journal of pharmacology and experimental therapeutics, 1975, Volume: 192, Issue:3 Topics: Animals; Bile Ducts; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cholestasis; Glomerular Filtration Rate; Glucuronates; Iodine Radioisotopes; Iopanoic Acid; Kidney; Kinetics; Lithocholic Acid; Liver; Male; Naphthalenes; Proadifen; Rats; Taurocholic Acid; Thiocyanates	1975
Acute cholestasis induced by lithocholic acid in the rat. A freeze-fracture replica and thin section study. Laboratory investigation; a journal of technical methods and pathology, 1975, Volume: 32, Issue:4 Topics: Animals; Bile; Bile Ducts, Intrahepatic; Cholestasis; Cholic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Female; Freeze Fracturing; Golgi Apparatus; Infusions, Parenteral; Lithocholic Acid; Liver; Lysosomes; Microscopy, Electron; Microtomy; Mitochondria, Liver; Rats; Secretory Rate	1975
Medical treatment of gallstones. Southern medical journal, 1975, Volume: 68, Issue:1 Topics: Animals; Arteriosclerosis; Bile; Chenodeoxycholic Acid; Cholelithiasis; Cholestasis; Cholesterol; Diarrhea; Humans; Lipid Metabolism; Lithocholic Acid; Liver; Macaca mulatta; Phenobarbital; Phosphatidylcholines; Placebos	1975
Scanning electron microscopy of the rat liver. Studies of the effect of taurolithocholate and other models of cholestasis. Gastroenterology, 1975, Volume: 69, Issue:3 Topics: Animals; Bile; Bile Ducts, Intrahepatic; Cholestasis; Dilatation, Pathologic; Disease Models, Animal; Ethinyl Estradiol; Female; Ligation; Lithocholic Acid; Liver; Male; Microscopy, Electron, Scanning; Rats; Secretory Rate; Taurocholic Acid	1975
Tight junction permeability and liver plasma membrane fluidity in lithocholate-induced cholestasis. Experimental and molecular pathology, 1992, Volume: 57, Issue:1 Topics: Animals; Cell Membrane; Cell Membrane Permeability; Cholestasis; Cholesterol; Disease Models, Animal; Injections; Intercellular Junctions; Inulin; Lanthanum; Lithocholic Acid; Liver; Male; Membrane Fluidity; Phospholipids; Rats; Rats, Sprague-Dawley; Statistics as Topic; Time Factors	1992
Bile secretion of sulfated glycolithocholic acid is required for its cholestatic action in rats. The American journal of physiology, 1992, Volume: 262, Issue:2 Pt 1 Topics: Animals; Bile; Calcium; Cholestasis; Cytoplasm; Glycocholic Acid; Lithocholic Acid; Liver; Male; Rats; Rats, Inbred Strains; Rats, Mutant Strains; Vacuoles	1992
Pathogenesis of lithocholate-induced intrahepatic cholestasis: role of glucuronidation and hydroxylation of lithocholate. Biochimica et biophysica acta, 1992, Jun-05, Volume: 1126, Issue:1 Topics: Animals; Bile; Bile Acids and Salts; Cholestasis; Cholesterol; Glucuronidase; Hydroxylation; Lithocholic Acid; Liver; Male; Phospholipids; Rats; Rats, Inbred Strains	1992
Low protein diets potentiate lithocholic acid-induced cholestasis in rats. The Journal of nutrition, 1992, Volume: 122, Issue:7 Topics: Animals; Bile Acids and Salts; Cholestasis; Dietary Proteins; Energy Intake; Female; Injections, Intravenous; Lithocholic Acid; Liver; Organ Size; Rats; Rats, Inbred Strains	1992
Do intracellular Ca2+ activity and hepatic glutathione play a role in the pathogenesis of lithocholic acid-induced cholestasis? Toxicology letters, 1992, Volume: 61, Issue:2-3 Topics: Acetaminophen; Animals; Calcium; Cholestasis; Drug Synergism; Glutathione; Injections, Intravenous; Lithocholic Acid; Liver; Male; Phosphorylases; Rats; Rats, Inbred Strains	1992
The effect of taurine on the cholestatic potential of sulfated lithocholate and its conjugates. Liver, 1991, Volume: 11, Issue:3 Topics: Animals; Bile; Bile Acids and Salts; Cholestasis; Guinea Pigs; Lithocholic Acid; Liver; Male; Taurine; Taurolithocholic Acid	1991
Cholestasis induced by lithocholate and its glucuronide: their biliary excretion and metabolism. Biochimica et biophysica acta, 1991, Jan-04, Volume: 1081, Issue:1 Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Bile; Bile Acids and Salts; Bilirubin; Cholestasis; Chromatography, Thin Layer; Glucuronates; Kinetics; Lithocholic Acid; Male; Rats; Rats, Inbred Strains; Spectrometry, Mass, Fast Atom Bombardment	1991
Effects of lithocholic acid exposure throughout pregnancy on late prenatal and early postnatal development in rats. Teratology, 1991, Volume: 43, Issue:4 Topics: Alkaline Phosphatase; Animals; Cholestasis; Embryonic and Fetal Development; Female; Fetal Growth Retardation; Growth; Lithocholic Acid; Liver; Male; Maternal-Fetal Exchange; Pregnancy; Pregnancy Complications; Rats; Rats, Inbred Strains	1991
Taurohyocholate, taurocholate, and tauroursodeoxycholate but not tauroursocholate and taurodehydrocholate counteract effects of taurolithocholate in rat liver. Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1990, Volume: 190, Issue:2 Topics: Animals; Bile Acids and Salts; Biotransformation; Cholestasis; In Vitro Techniques; Lithocholic Acid; Male; Rats; Taurolithocholic Acid	1990
The influence of severity of bile flow reduction, cycloheximide, and methyl isobutyl ketone pretreatment on the kinetics of taurolithocholic acid disposition in the rat. Toxicology and applied pharmacology, 1990, Jun-15, Volume: 104, Issue:2 Topics: Animals; Bile; Cholestasis; Cycloheximide; Drug Synergism; Ketones; Kinetics; Lithocholic Acid; Male; Metabolic Clearance Rate; Methyl n-Butyl Ketone; Rats; Rats, Inbred Strains; Secretory Rate; Taurolithocholic Acid	1990
Cholesterol and bile acid metabolism in cultures of primary rat bile ductular epithelial cells. Hepatology (Baltimore, Md.), 1990, Volume: 11, Issue:6 Topics: Animals; Bile Acids and Salts; Bile Ducts; Cell Separation; Cells, Cultured; Cholestasis; Cholesterol; Cholic Acid; Cholic Acids; Deoxycholic Acid; Epithelial Cells; Epithelium; Lithocholic Acid; Male; Rats; Rats, Inbred Strains; Ursodeoxycholic Acid	1990
Tauroursodeoxycholate prevents taurolithocholate-induced cholestasis and toxicity in rat liver. Journal of hepatology, 1990, Volume: 10, Issue:3 Topics: Animals; Chenodeoxycholic Acid; Cholestasis; Lithocholic Acid; Liver; Rats; Taurochenodeoxycholic Acid; Taurolithocholic Acid	1990
Lithocholate in liver tissue with obstructive jaundice. Gastroenterologia Japonica, 1989, Volume: 24, Issue:2 Topics: Cholestasis; Gas Chromatography-Mass Spectrometry; Humans; Lithocholic Acid; Liver	1989
Effect of inhibition of protein synthesis on cholestasis induced by taurolithocholate, lithocholate, and a manganese-bilirubin combination in the rat. Biochemical pharmacology, 1989, Aug-01, Volume: 38, Issue:15 Topics: Animals; Bilirubin; Cholestasis; Cycloheximide; Disease Models, Animal; Lithocholic Acid; Male; Manganese; Protein Synthesis Inhibitors; Rats; Rats, Inbred Strains; Taurolithocholic Acid; Time Factors	1989
Effect of taurolithocholate on in vivo sulfation and glucuronidation of acetaminophen in rats. Pharmaceutical research, 1988, Volume: 5, Issue:1 Topics: Acetaminophen; Animals; Cholestasis; Lithocholic Acid; Male; Rats; Rats, Inbred Strains; Taurolithocholic Acid	1988
Cholestasis and the interactions of sulfated glyco- and taurolithocholate with calcium. The American journal of physiology, 1988, Volume: 254, Issue:5 Pt 1 Topics: Animals; Bile Acids and Salts; Calcium; Calcium Phosphates; Cholestasis; Hydrogen-Ion Concentration; Lithocholic Acid; Male; Micelles; Rats; Rats, Inbred Strains; Splanchnic Circulation; Taurolithocholic Acid	1988
Cholesterol synthesis in the pathogenesis of lithocholic acid-induced cholestasis. Lipids, 1988, Volume: 23, Issue:3 Topics: Animals; Bile; Carbon Radioisotopes; Cholestasis; Cholesterol; Clofibrate; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lithocholic Acid; Liver; Lovastatin; Male; Rats; Rats, Inbred Strains	1988
Reduced cholestatic potency of taurolithocholate during backward perfusion of the rat liver. Laboratory investigation; a journal of technical methods and pathology, 1987, Volume: 56, Issue:6 Topics: Animals; Bile Canaliculi; Biotransformation; Cholestasis; Hydroxylation; Lithocholic Acid; Liver; Male; Necrosis; Perfusion; Rats; Rats, Inbred Strains; Taurolithocholic Acid	1987
The effect of colchicine on the development of lithocholic acid-induced cholestasis. A study of the role of microtubules in intracellular cholesterol transport. The Biochemical journal, 1986, Jun-01, Volume: 236, Issue:2 Topics: Animals; Bile; Biological Transport; Cell Membrane; Cholestasis; Cholesterol; Colchicine; Lithocholic Acid; Liver; Male; Microtubules; Phospholipids; Rats; Rats, Inbred Strains	1986
Metabolism and cholestatic effect of 3 alpha-hydroxy-7 xi-methyl-5 beta-cholanoic acid. Lipids, 1985, Volume: 20, Issue:4 Topics: Animals; Bile; Cholestasis; Chromatography, Thin Layer; Cricetinae; Lithocholic Acid; Male; Mesocricetus	1985
Taurolithocholate-induced intrahepatic cholestasis: potentiation by methyl isobutyl ketone and methyl n-butyl ketone in rats. Toxicology and applied pharmacology, 1985, Sep-15, Volume: 80, Issue:2 Topics: Animals; Bile; Cholestasis; Drug Synergism; Hexanones; Injections, Intravenous; Ketones; Lithocholic Acid; Male; Methyl n-Butyl Ketone; Rats; Rats, Inbred Strains; Taurolithocholic Acid	1985
Sulphated lithocholic acid conjugates in serum from children with hepatic and intestinal diseases. Scandinavian journal of gastroenterology, 1985, Volume: 20, Issue:10 Topics: Adolescent; Child; Child, Preschool; Cholestasis; Glycocholic Acid; Humans; Infant; Infant, Newborn; Intestinal Diseases; Lithocholic Acid; Liver Diseases	1985
Identification and quantitative determination of urinary bile acids excreted in cholestasis. Clinica chimica acta; international journal of clinical chemistry, 1973, Mar-14, Volume: 44, Issue:2 Topics: Acute Disease; Adolescent; Adult; Aged; Bile Acids and Salts; Cholelithiasis; Cholestasis; Chromatography, Gas; Chromatography, Ion Exchange; Deoxycholic Acid; Hepatitis A; Humans; Jaundice; Lithocholic Acid; Mass Spectrometry; Middle Aged	1973
Clinical aspects of alterations in bile acid metabolism--the wrong bile acids in the wrong place. Scottish medical journal, 1973, Volume: 18, Issue:5 Topics: Bile Acids and Salts; Biliary Tract Diseases; Celiac Disease; Chenodeoxycholic Acid; Cholestasis; Colonic Diseases; Diarrhea; Hepatitis A; Ileum; Intestinal Mucosa; Intestine, Small; Lithocholic Acid; Liver Cirrhosis; Malabsorption Syndromes; Neomycin; Pancreatitis; Pruritus; Zollinger-Ellison Syndrome	1973
[The primary hepatic synthesis of mono-hydroxy bile acids in extrahepatic biliary atresia (author's transl)]. Klinische Wochenschrift, 1973, Sep-15, Volume: 51, Issue:18 Topics: Animals; Bile Acids and Salts; Bile Ducts; Biliary Tract Diseases; Biopsy; Biotransformation; Carbon Radioisotopes; Cholestasis; Cholesterol; Cholic Acids; Chromatography, Gas; Chromatography, Thin Layer; Deoxycholic Acid; Feces; Humans; Lithocholic Acid; Liver; Liver Cirrhosis; Microsomes, Liver; Mitochondria, Liver; Rats	1973
[Bile acids in the serum of patients with extrahepatic cholestasis with chronic liver diseases]. Zeitschrift fur Gastroenterologie, 1973, Volume: 11, Issue:4 Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Chronic Disease; Deoxycholic Acid; Hepatic Encephalopathy; Hepatitis; Humans; Lithocholic Acid; Liver Cirrhosis; Liver Diseases	1973
[Formation of bile acid sulfate esters in perfused rat livers following bile duct occlusion]. Zeitschrift fur Gastroenterologie, 1974, Volume: 12, Issue:2 Topics: Animals; Bile Acids and Salts; Carbon Radioisotopes; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Esters; Lithocholic Acid; Liver; Male; Perfusion; Rats; Sulfates; Taurocholic Acid	1974
Proceedings: Experimental production of lipoprotein X (LPX) in the absence of obstructive jaundice. Gut, 1974, Volume: 15, Issue:4 Topics: Animals; Cholestasis; Lipoproteins; Lithocholic Acid; Metabolism; Phosphatidylcholines; Rabbits	1974