lithium-chloride has been researched along with Retinal-Neovascularization* in 1 studies
1 other study(ies) available for lithium-chloride and Retinal-Neovascularization
| Article | Year |
|---|---|
Fzd7 (Frizzled-7) Expressed by Endothelial Cells Controls Blood Vessel Formation Through Wnt/β-Catenin Canonical Signaling.
Vessel formation requires precise orchestration of a series of morphometric and molecular events controlled by a multitude of angiogenic factors and morphogens. Wnt/frizzled signaling is required for proper vascular formation. In this study, we investigated the role of the Fzd7 (frizzled-7) receptor in retinal vascular development and its relationship with the Wnt/β-catenin canonical pathway and Notch signaling.. Fzd7 expressed by EC drives postnatal angiogenesis via activation of Dvl/β-catenin signaling and can control the integrative interaction of Wnt and Notch signaling during postnatal angiogenesis. Topics: Adaptor Proteins, Signal Transducing; Animals; Animals, Newborn; beta Catenin; Calcium-Binding Proteins; Cell Proliferation; Cells, Cultured; Dishevelled Proteins; Endothelial Cells; Frizzled Receptors; Genotype; Intracellular Signaling Peptides and Proteins; Jagged-1 Protein; Lithium Chloride; Membrane Proteins; Mice, Inbred C57BL; Mice, Knockout; Neovascularization, Physiologic; Phenotype; Receptors, G-Protein-Coupled; Receptors, Notch; Retinal Neovascularization; Retinal Vessels; RNA Interference; Transfection; Wnt Signaling Pathway | 2016 |