lithium-chloride and Intestinal-Neoplasms

lithium-chloride has been researched along with Intestinal-Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for lithium-chloride and Intestinal-Neoplasms

Article	Year
Apc-mutant cells act as supercompetitors in intestinal tumour initiation. Nature, 2021, Volume: 594, Issue:7863 A delicate equilibrium of WNT agonists and antagonists in the intestinal stem cell (ISC) niche is critical to maintaining the ISC compartment, as it accommodates the rapid renewal of the gut lining. Disruption of this balance by mutations in the tumour suppressor gene APC, which are found in approximately 80% of all human colon cancers, leads to unrestrained activation of the WNT pathway Topics: Adenoma; Adenomatous Polyposis Coli Protein; Animals; Cell Competition; Cell Differentiation; Female; Genes, APC; Glycogen Synthase Kinase 3 beta; Humans; Intestinal Neoplasms; Lithium Chloride; Male; Mice; Mutation; Organoids; Wnt Proteins	2021

Article

Year

Apc-mutant cells act as supercompetitors in intestinal tumour initiation.

Nature, 2021, Volume: 594, Issue:7863

A delicate equilibrium of WNT agonists and antagonists in the intestinal stem cell (ISC) niche is critical to maintaining the ISC compartment, as it accommodates the rapid renewal of the gut lining. Disruption of this balance by mutations in the tumour suppressor gene APC, which are found in approximately 80% of all human colon cancers, leads to unrestrained activation of the WNT pathway

Topics: Adenoma; Adenomatous Polyposis Coli Protein; Animals; Cell Competition; Cell Differentiation; Female; Genes, APC; Glycogen Synthase Kinase 3 beta; Humans; Intestinal Neoplasms; Lithium Chloride; Male; Mice; Mutation; Organoids; Wnt Proteins

2021