lithium-chloride and Infections

lithium-chloride has been researched along with Infections* in 2 studies

Other Studies

2 other study(ies) available for lithium-chloride and Infections

Article	Year
Lipopolysaccharide (LPS) induced sickness in adolescent female rats alters the acute-phase response and lithium chloride (LiCl)- induced impairment of conditioned place avoidance/aversion learning, following a homotypic LPS challenge in adulthood. Behavioural brain research, 2018, 10-01, Volume: 351 The multi-variable locomotor activity effects of LiCl treatment in female rats were examined in a conditioned place avoidance/aversion (CPA) paradigm. In addition, the sickness effects of an LPS injection (200 μg/kg), given during adolescents, on CPA learning in adulthood were examined, as were the effects of a homotypic LPS injection (200 μg/kg) just prior to CPA acquisition trials. Female rats were injected with LPS or saline during adolescents (6 weeks of age) and later pretreated with LPS again or saline in an automated two-chamber CPA paradigm with LiCl (95 mg/kg) treatments as the aversive toxin. Results showed that, while adolescent LPS treatment had no long-term effect on the establishment of CPA, it did interfere with the ability of a second LPS challenge in adulthood to impair CPA learning, an effect obtained in subjects pretreated with LPS in the CPA procedure in adulthood only. The results of this study demonstrate the importance of considering the adolescent stage of development when evaluating the effects of environmental challenges on adult behavior. Topics: Animals; Avoidance Learning; Conditioning, Psychological; Female; Illness Behavior; Infections; Lipopolysaccharides; Lithium Chloride; Motor Activity; Rats, Long-Evans; Sexual Maturation; Spatial Behavior	2018
Postburn serum inhibits in vitro production of colony-stimulating factor by mononuclear peripheral blood cells. International journal of cell cloning, 1986, Volume: 4, Issue:6 The effects of postburn serum (PBS) on the production of colony-stimulating factor (CSF) was evaluated in 13 burned patients by adding PBS to normal peripheral blood mononuclear cells (MNC) and assaying the MNC-conditioned media for CSF content. PBS inhibited CSF production by at least 50%. PBS from non-survivors significantly inhibited CSF production more than PBS from survivors. The addition of lithium chloride restored production of CSF in the presence of day 15 PBS but could not overcome the inhibitory effects of day 1 or day 8 PBS. The nature of the inhibitor(s) is uncertain, but correction of the CSF production defect by lithium chloride later in the course of thermal injury suggests that the defect may be reversible. Topics: Adult; Burns; Chlorides; Colony-Stimulating Factors; Granulocytes; Hematopoiesis; Humans; In Vitro Techniques; Infections; Leukocytes; Lithium; Lithium Chloride; Middle Aged	1986

Article

Year

Lipopolysaccharide (LPS) induced sickness in adolescent female rats alters the acute-phase response and lithium chloride (LiCl)- induced impairment of conditioned place avoidance/aversion learning, following a homotypic LPS challenge in adulthood.

Behavioural brain research, 2018, 10-01, Volume: 351

The multi-variable locomotor activity effects of LiCl treatment in female rats were examined in a conditioned place avoidance/aversion (CPA) paradigm. In addition, the sickness effects of an LPS injection (200 μg/kg), given during adolescents, on CPA learning in adulthood were examined, as were the effects of a homotypic LPS injection (200 μg/kg) just prior to CPA acquisition trials. Female rats were injected with LPS or saline during adolescents (6 weeks of age) and later pretreated with LPS again or saline in an automated two-chamber CPA paradigm with LiCl (95 mg/kg) treatments as the aversive toxin. Results showed that, while adolescent LPS treatment had no long-term effect on the establishment of CPA, it did interfere with the ability of a second LPS challenge in adulthood to impair CPA learning, an effect obtained in subjects pretreated with LPS in the CPA procedure in adulthood only. The results of this study demonstrate the importance of considering the adolescent stage of development when evaluating the effects of environmental challenges on adult behavior.

Topics: Animals; Avoidance Learning; Conditioning, Psychological; Female; Illness Behavior; Infections; Lipopolysaccharides; Lithium Chloride; Motor Activity; Rats, Long-Evans; Sexual Maturation; Spatial Behavior

2018

Postburn serum inhibits in vitro production of colony-stimulating factor by mononuclear peripheral blood cells.

International journal of cell cloning, 1986, Volume: 4, Issue:6

The effects of postburn serum (PBS) on the production of colony-stimulating factor (CSF) was evaluated in 13 burned patients by adding PBS to normal peripheral blood mononuclear cells (MNC) and assaying the MNC-conditioned media for CSF content. PBS inhibited CSF production by at least 50%. PBS from non-survivors significantly inhibited CSF production more than PBS from survivors. The addition of lithium chloride restored production of CSF in the presence of day 15 PBS but could not overcome the inhibitory effects of day 1 or day 8 PBS. The nature of the inhibitor(s) is uncertain, but correction of the CSF production defect by lithium chloride later in the course of thermal injury suggests that the defect may be reversible.

Topics: Adult; Burns; Chlorides; Colony-Stimulating Factors; Granulocytes; Hematopoiesis; Humans; In Vitro Techniques; Infections; Leukocytes; Lithium; Lithium Chloride; Middle Aged

1986