lithium has been researched along with Status Epilepticus in 169 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (5.33) | 18.7374 |
| 1990's | 31 (18.34) | 18.2507 |
| 2000's | 59 (34.91) | 29.6817 |
| 2010's | 52 (30.77) | 24.3611 |
| 2020's | 18 (10.65) | 2.80 |
| Authors | Studies |
|---|---|
| Dehpour, AR; Eslami, F; Ghasemi, M; Koohfar, A; Maadani, M; Moradi, F; Rahimi, N; Shayan, M | 1 |
| Amanlou, A; Dehpour, AR; Dejban, P; Eslami, F; Rahimi, N; Shayan, M | 1 |
| Aripaka, SS; Bankstahl, JP; Bankstahl, M; Bascuñana, P; Mikkelsen, JD; Pazarlar, BA | 1 |
| Gupta, YK; Joshi, D; Katyal, J; Kumar, H | 1 |
| Ahmed, N; Ahmed, Y; Alshafei, H; Alshafei, R; Ashraf, N; El-Derany, MO; Ezz, S; George, MY; Ibrahim, C; Ibrahim, SS; Khaled, G; Khaled, H; Saleh, A; Waleed, H; Zaher, M | 1 |
| Delgado, M; Fernández de la Rosa, R; García-García, L; Gomez, F; Pozo, MÁ | 1 |
| Baldwin, RA; Niquet, J; Suchomelova, L; Thompson, KW; Wasterlain, CG | 1 |
| Cumbres-Vargas, IM; Pichardo-Macías, LA; Ramírez-San Juan, E; Zamudio, SR | 1 |
| Bolshakov, AP; Borisova, MA; Karan, AA; Suleymanova, EM; Volobueva, MN | 1 |
| Diespirov, GP; Griflyuk, AV; Kovalenko, AA; Postnikova, TY; Zaitsev, AV | 1 |
| Bascuñana, P; Delgado, M; García-García, L; Gomez, F; Hernández-Martín, N; Pozo, MÁ; Rosa, RF; Silván, Á | 1 |
| Banerjee, J; Chandra, PS; Dixit, AB; Dubey, V; Jain, S; Pandey, S; Roy, A; Tripathi, M | 1 |
| Katyal, J; Kumar Gupta, Y; Kumar, H | 1 |
| GuiLian, Z; HaiQin, W; Hong, S; HongWei, R; JiaWen, W; ShuQin, Z; Xin, Y; YongNan, L; Zhen, G | 1 |
| Chen, L; Peng, Y; Qu, Y; Wang, D; Zhu, Y | 1 |
| Chiu, SC; Huang, CW; Lai, MC; Liu, PY; Wu, SN; Yang, CS | 1 |
| Annamalai, K; Kutty, BM; Nair, KP; Salaka, RJ; Shankaranarayana Rao, BS; Srikumar, BN | 1 |
| Charret, TS; Cristina Rheder Fagundes Pascoal, A; Lopes-Cendes, I; Pascoal, VDB; Pereira, MTM | 1 |
| de Oliveira, DL; Gonçalves, CA; Hennemann, MM; Vizuete, AFK | 1 |
| Lin, Z; Pan, S; Wang, Y; Xie, L; Yang, T | 1 |
| Cai, Q; Gan, J; Li, S; Luo, R; Mu, D; Qu, Y; Wan, C | 1 |
| Bahremand, T; Dehpour, AR; Eslami, SM; Ghasemi, M; Gholami, M; Momeny, M; Sharifzadeh, M | 1 |
| Qu, Y; Wang, A; Zhang, H | 1 |
| Fukumura, S; Honmou, O; Kataoka-Sasaki, Y; Kocsis, JD; Morita, T; Nagahama, H; Nakazaki, M; Oka, S; Sakai, T; Sasaki, M; Tsutsumi, H | 1 |
| Feng, P; Hölscher, C; Li, DF; Tian, MJ; Wang, RF; Xue, GF; Zheng, JY | 1 |
| Ben-Hur, T; Blatch, D; Ekstein, D; Eyal, S; Han, H; Inbar, D; Mann, A; Portnoy, E; Shmuel, M | 1 |
| Chen, SH; Jin, MF; Li, LL; Ni, H | 1 |
| Kuang, F; Liu, JT; Wu, SX; Zhang, H | 1 |
| Kim, KK; Lukomskaya, NY; Magazanik, LG; Vataev, SI; Zaitsev, AV | 1 |
| Domínguez-Valentín, AE; Hernández-Moreno, A; Orozco-Suárez, S; Rocha, L; Santana-Gómez, CE; Valle-Dorado, MG | 1 |
| Al Kury, LT; Bogovyk, R; Fedoriuk, M; Isaeva, E; Krishtal, O; Nikolaienko, O; Savotchenko, A; Semenikhina, M | 1 |
| Gao, F; Li, YJ; Wang, L; Yang, CM; Zhang, B | 1 |
| Barker-Haliski, M; DiCamillo, A; Gruner, JA; Hinchliffe, R; Saporito, MS; White, HS | 1 |
| Atilla, P; Aydemir, O; Barun, S; Bulduk, EB; Kiziltas, M; Kurt, G; Muftuoglu, S; Oktem, M; Turhan, T | 1 |
| Chen, Y; Sun, M; van Luijtelaar, G; Wang, J; Wang, Q | 1 |
| Gao, F; Jia, N; Jia, R; Jiang, W; Jiang, Y; Li, R; Liu, Z; Wang, L; Wu, S; Yang, F; Zhang, H; Zhang, S; Zhang, Z; Zhao, J | 1 |
| Dyomina, AV; Kalemenev, SV; Karepanov, AA; Lavrentyeva, VV; Smolensky, IV; Zaitsev, AV; Zubareva, OE | 1 |
| Akimana, G; Carneiro, JE; Cassel, JC; Cosquer, B; Faure, JB; Ferrandon, A; Geiger, K; Koning, E; Nehlig, A; Penazzi, L | 1 |
| Dudek, FE; Ekstrand, JJ; Scholl, EA | 1 |
| Beltrán-Parrazal, L; López-Meraz, ML; Manzo, J; Medel-Matus, JS; Morgado-Valle, C; Pérez-Estudillo, C | 1 |
| Chun, KP; Duffy, BA; Lythgoe, MF; Ma, D; Scott, RC | 1 |
| Hillert, MH; Imran, I; Klein, J; Lau, H; Weinfurter, S; Zimmermann, M | 1 |
| Bos, IW; de Graan, PN; Hessel, EV; Mulder, SD; van der Hel, WS; van Eijsden, P; Verlinde, SA | 1 |
| Ahmad, M; Wadaan, MA | 1 |
| Brandt, C; Erker, T; Löscher, W; Töllner, K | 1 |
| Löscher, W | 1 |
| Baldwin, R; Gezalian, M; Niquet, J; Wasterlain, CG | 1 |
| Bascuñana, P; de Cristóbal, J; Delgado, M; Fernández de la Rosa, R; García-García, L; Pozo, MA; Shiha, AA | 1 |
| Årstad, E; Badar, A; Duffy, BA; Lythgoe, MF; Patel, N | 1 |
| Ren, J; Sun, H; Wu, H; Zhan, S; Zhang, G; Zhang, H; Zhang, R | 1 |
| Hillert, MH; Imran, I; Klein, J | 1 |
| Bröer, S; Löscher, W | 1 |
| Agredano-Moreno, LT; Arriaga-Ávila, V; Carrera-Calvo, D; Córdova-Dávalos, L; Guevara-Guzmán, R; Jiménez-García, LF; Mercado-Gómez, OF; Solís-Navarrete, J | 1 |
| Álvarez-Croda, DM; Beltrán-Parrazal, L; López-Meraz, ML; Martínez-Quiroz, J; Medel-Matus, JS; Puig-Lagunes, AA; Santiago-García, J | 1 |
| Gulec Suyen, G; Isbil-Buyukcoskun, N; Kahveci, N; Ozluk, K; Sengun, E | 1 |
| Kim, KK; Kryukov, KA; Magazanik, LG; Zaitsev, AV | 1 |
| Al Ghamdi, S; ALrefai, AA; Alshareef, A; Bin Sef, B; Borham, LE; Ibrahim, IAA; Khan, M; Labib, AA; Mahfoz, AM; Milibary, A; Shahzad, N | 1 |
| Kalemenev, SV; Kim, KK; Lavrent'eva, VV; Lukomskaya, NY; Magazanik, LG; Sizov, VV; Zaitsev, AV; Zubareva, OE | 1 |
| Cheng, JT; Huang, CC; Huang, CW; Tsai, JJ; Wu, SN | 1 |
| Han, SR; Kim, YI; Park, J; Park, S; Rhyu, S; Shin, C | 1 |
| Guo, Y; Jiang, L | 1 |
| Cui, XN; Porter, BE; Varodayan, FP; Zhu, XJ | 1 |
| Baldwin, RA; Liu, H; Mazarati, AM; Naylor, DE; Niquet, J; Suchomelova, L; Thompson, KW; Wasterlain, CG | 1 |
| Cheung, KK; Choy, M; Gadian, DG; Lythgoe, MF; Scott, RC; Thomas, DL | 1 |
| Costa-Ferro, ZS; Cunha, FB; DaCosta, JC; Machado, DC; Pedroso, MF; Ribeiro-dos-Santos, R; Soares, MB; Vitola, AS; Xavier, LL | 1 |
| Hao, A; Huang, Y; Li, L; Liu, J; Wang, A; Xue, P | 1 |
| Cai, GE; Ju, G; Li, ST; Lu, QC; Yang, Q; Zhang, Y | 1 |
| Deng, Y; Feng, D; Huang, Y; Liu, Y; Sun, Z; Wang, H; Wang, W; Zhang, Y; Zhao, G | 1 |
| Battastini, AM; Bonan, CD; da Silveira, VG; de Paula Cognato, G; Figueiró, F; Müller, AP; Perry, ML | 1 |
| Feng, L; Hu, K; Li, Y; Long, L; Long, X; Xiao, B; Zhang, C | 1 |
| Baykara, B; Kurul, SH; Sözmen, SÇ; Tuğyan, K; Yılmaz, O; Yiş, U | 1 |
| Holmes, GL; Lenck-Santini, PP; Mahoney, JM; Richard, GR; Scott, RC; Tyler, AL | 1 |
| Fang, Y; Li, JL; Li, LY; Wang, K; Wang, Y; Yang, WM; Zhang, HM | 1 |
| Feng, L; Hu, K; Li, Y; Long, HY; Long, LL; Ouyang, DS; Sun, DN; Xiao, B; Xie, YY; Zhang, C | 1 |
| Liu, H; Mazarati, A; Sankar, R; Shin, D; Wasterlain, C | 1 |
| Dubé, C; Koning, E; Nehlig, A | 1 |
| Audenino, D; Cocito, L; Primavera, A; Roccatagliata, L | 1 |
| Alsaadi, TM; Gansaeuer, M | 1 |
| Chambron, J; Mauss, Y; Namer, IJ; Roch, C; Yu, O | 1 |
| Brooks-Kayal, AR; Budreck, EC; Raol, YS | 1 |
| Druga, R; Haugvicová, R; Kubová, H; Suchomelová, L | 1 |
| Sankar, R; Shin, D; Wasterlain, CG | 1 |
| André, V; Ferrandon, A; Koning, E; Nehlig, A; Rigoulot, MA | 1 |
| Goodkin, HP; Holmes, GL; Liu, X | 1 |
| Akman, C; Boukhezra, O; Fu, DD; Holmes, GL; Lui, X; Riviello, P; Zhao, Q | 1 |
| Ferrandon, A; Koning, E; Nehlig, A; Rigoulot, MA | 1 |
| Hsieh, CS; Huang, LT; Lai, MC; Liou, CW; Wang, CA; Wang, CL; Yang, CH; Yang, SN | 1 |
| Keller, AF; Leroy, C; Nehlig, A; Poisbeau, P | 1 |
| Akman, C; Cha, BH; Holmes, GL; Liu, X; Silveira, DC | 1 |
| Griffith, JW; Peterson, SL; Purvis, RS | 2 |
| Koning, E; Nehlig, A; Raffo, E | 1 |
| Braun, KP; de Graan, PN; Nicolay, K; Notenboom, RG; van Eijsden, P; van Nieuwenhuizen, O; Wu, O | 1 |
| Ferrandon, A; Guenounou, M; Kaplan, H; Koning, E; Motte, J; Nehlig, A; Voutsinos-Porche, B | 1 |
| Bissoon, N; Gurd, JW; Ikeda-Douglas, C; Milgram, NW; Moussa, R; Niimura, M | 1 |
| Holmes, GL; Hsieh, CS; Huang, LT; Lai, MC; Lee, CH; Lee, KH; Tiao, MM; Wang, CA; Wu, CL; Yang, SN | 1 |
| Dykstra, CM; Gurd, JW; Huo, JZ | 1 |
| Bartolini, M; Bellesi, M; Passamonti, L; Provinciali, L; Silvestrini, M | 1 |
| Holmes, GL; Marolewski, A; Rusche, JR; Zhao, Q | 1 |
| Brooks-Kayal, AR; Cui, XN; Porter, BE | 1 |
| Ferrandon, A; François, J; Koning, E; Nehlig, A | 1 |
| Brooks-Kayal, AR; Lund, IV; Maronski, MA; Porter, BE; Raol, YH; Zhang, G | 1 |
| Boehm, N; Hanaya, R; Nehlig, A | 1 |
| Bamidele, A; Begum, S; Choy, M; de Castro, SC; Gadian, DG; Greene, ND; Leung, KY; Lythgoe, MF; Scott, RC; Wait, R | 1 |
| Yeung, WT; Yip, KK | 1 |
| Ahmad, M; Deeb, SA; Moutaery, KA; Tariq, M | 1 |
| Feng, HJ; Kao, C; Macdonald, RL; Mathews, GC | 1 |
| Deng, YC; Huang, YG; Li, YN; Shao, XG; Sun, H; Yang, J; Yu, X | 1 |
| Chi, Z; Dai, T; Shan, P; Song, Z; Wang, R; Wang, S | 1 |
| Brown, IR; Lively, S | 1 |
| Erwin, CW; Weiner, RD; Whanger, AD; Wilson, WP | 1 |
| Du, F; Eid, T; Köhler, C; Lothman, EW; Schwarcz, R | 1 |
| Handforth, A; Treiman, DM | 2 |
| Daniels, AH; Fujikawa, DG; Kim, JS | 1 |
| Bureau, YR; Persinger, MA | 1 |
| Balla, J; Radtke, RA; Sibert, TE; Weiner, RD | 1 |
| Baldwin, RA; Baxter, CF; Wasterlain, CG | 1 |
| Diamantis, W; Gels, M; Gordon, R; Sofia, RD | 1 |
| George, B; Kulkarni, SK | 3 |
| Belluardo, N; Condorelli, DF; Jiang, XH; Mudo, G | 1 |
| Sankar, R; Shin, DH; Wasterlain, CG | 1 |
| Wasterlain, CG | 1 |
| Nagy, AK; Treiman, DM; Walton, NY | 2 |
| Aguiar, LM; de Bruin, VM; de Pinho, RS; de Sousa, FC; Marinho, MM; Viana, GS | 1 |
| Baram, TZ; Fernandes, MJ; Motte, J; Nehlig, A | 1 |
| George, B; Kulkarni, SK; Mathur, R | 1 |
| Liu, H; Mazarati, A; Pereira de Vasconcelos, A; Sankar, R; Shin, DH; Wasterlain, CG | 1 |
| André, V; Covolan, L; Dubé, C; Ferrandon, A; Marescaux, C; Nehlig, A | 1 |
| Boyet, S; Dubé, C; Fernandes, MJ; Marescaux, C; Nehlig, A | 1 |
| Cai, B; Fujikawa, DG; Shinmei, SS | 2 |
| Eraković, V; Laginja, J; Simonić, A; Varljen, J; Zupan, G | 1 |
| André, V; Ferrandon, A; Marescaux, C; Nehlig, A | 2 |
| Dubé, C; Marescaux, C; Nehlig, A | 1 |
| Katsumori, H; Liu, H; Sankar, R; Shin, D; Wasterlain, CG | 1 |
| Mastrosov, L; Parker, G; Peredery, O; Persinger, MA | 1 |
| Güleç, G; Noyan, B | 1 |
| Druga, R; Hlinák, Z; Krsek, P; Mares, P; Mikulecká, A | 1 |
| Boyet, S; Dubé, C; Marescaux, C; Nehlig, A | 1 |
| Chaudhary, G; Gupta, YK | 1 |
| Brandt, C; Ebert, U; Glien, M; Löscher, W; Potschka, H; Voigt, H | 1 |
| Ekdahl, CT; Elmér, E; Lindvall, O; Mohapel, P | 1 |
| Hsu, HY; Huang, LT; Lai, MC; Liou, CW; Tung, YR; Wang, TJ; Wu, CL | 1 |
| Jedrzejko, C; Persinger, MA | 1 |
| Ferrandon, A; Nehlig, A; Pereira de Vasconcelos, A | 1 |
| Liu, H; Sankar, R; Schreiber, SS; Shin, D; Tan, Z; Tu, W; Wasterlain, CG | 1 |
| Alexander, J; Kuruvilla, PK | 1 |
| Liu, KJ; Liu, S; Morrow, D; Peterson, SL | 1 |
| Baram, TZ; Hirsch, E; Snead, OC | 1 |
| Chrétien, R; Falter, H; Persinger, MA | 1 |
| Jope, RS; Kolasa, K; Ormandy, GC; Song, L | 1 |
| Gilles, F; Hirsch, E; Snead, OC; Vergnes, M | 1 |
| Gale, K; Pazos, A; Peterson, CJ; Vinayak, S | 1 |
| Coyle, JT; Saltarelli, MD; Yamada, K | 1 |
| Treiman, DM; Walton, NY | 2 |
| Gunawan, S; Treiman, DM; Walton, NY | 1 |
| Jope, RS; Ormandy, GC; Snead, OC | 1 |
| Ferraro, TN; Hare, TA; Jope, RS; Miller, JM | 1 |
| Jope, RS; Morrisett, RA; Snead, OC | 3 |
| Jope, RS; Morrisett, RA | 1 |
| Jope, RS; Lally, K; Simonato, M | 1 |
3 review(s) available for lithium and Status Epilepticus
| Article | Year |
|---|---|
Single versus combinatorial therapies in status epilepticus: Novel data from preclinical models.
Topics: Animals; Anticonvulsants; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Ketamine; Lithium; Phenobarbital; Pilocarpine; Rats; Seizures; Status Epilepticus | 2015 |
Lithium-pilocarpine neurotoxicity: a potential model of status epilepticus.
Topics: Animals; Disease Models, Animal; Lithium; Pilocarpine; Status Epilepticus | 1995 |
Recurrent seizures in the developing brain are harmful.
Topics: Adult; Animals; Brain; Brain Injuries; Child; Disease Models, Animal; Entorhinal Cortex; Epilepsy; Hippocampus; Humans; Lithium; Neural Pathways; Pilocarpine; Rats; Rats, Wistar; Recurrence; Status Epilepticus | 1997 |
166 other study(ies) available for lithium and Status Epilepticus
| Article | Year |
|---|---|
Modafinil exerts anticonvulsive effects against lithium-pilocarpine-induced status epilepticus in rats: A role for tumor necrosis factor-α and nitric oxide signaling.
Topics: Animals; Humans; Lithium; Modafinil; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pilocarpine; Rats; Status Epilepticus; Tumor Necrosis Factor-alpha | 2022 |
Pentylenetetrazole preconditioning attenuates severity of status epilepticus induced by lithium-pilocarpine in male rats: evaluation of opioid/NMDA receptors and nitric oxide pathway.
Topics: Analgesics, Opioid; Animals; Anticonvulsants; Enzyme Inhibitors; Lithium; Male; N-Methylaspartate; Nitric Oxide; Pentylenetetrazole; Pilocarpine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Signal Transduction; Status Epilepticus | 2022 |
Spatio-Temporal Alterations in Synaptic Density During Epileptogenesis in the Rat Brain.
Topics: Animals; Brain; Epilepsy; Female; Hippocampus; Lithium; Membrane Glycoproteins; Nerve Tissue Proteins; Pilocarpine; Rats; Status Epilepticus | 2022 |
Effect of morphine administration after status epilepticus on epileptogenesis in rats.
Topics: Animals; Disease Models, Animal; Epilepsy; Lithium; Morphine; Naloxone; Pilocarpine; Rats; Seizures; Status Epilepticus | 2022 |
Design and evaluation of chrysin-loaded nanoemulsion against lithium/pilocarpine-induced status epilepticus in rats; emphasis on formulation, neuronal excitotoxicity, oxidative stress, microglia polarization, and AMPK/SIRT-1/PGC-1α pathway.
Topics: AMP-Activated Protein Kinases; Animals; Epilepsy; Lithium; Microglia; Oxidative Stress; Pilocarpine; Rats; Status Epilepticus | 2023 |
The vasodilator naftidrofuryl attenuates short-term brain glucose hypometabolism in the lithium-pilocarpine rat model of status epilepticus without providing neuroprotection.
Topics: Animals; Brain; Disease Models, Animal; Glucose; Hippocampus; Humans; Lithium; Nafronyl; Neuroprotection; Pilocarpine; Rats; Seizures; Status Epilepticus; Vasodilator Agents | 2023 |
Interictal aggression in rats with chronic seizures after an early life episode of status epilepticus.
Topics: Aggression; Animals; Epilepsy; Lithium; Male; Pilocarpine; Rats; Rats, Wistar; Seizures; Status Epilepticus | 2023 |
Thalidomide Attenuates Epileptogenesis and Seizures by Decreasing Brain Inflammation in Lithium Pilocarpine Rat Model.
Topics: Animals; Disease Models, Animal; Encephalitis; Epilepsy, Temporal Lobe; Hippocampus; Lithium; Male; Pilocarpine; Rats; Rats, Sprague-Dawley; Seizures; Status Epilepticus; Thalidomide; Tumor Necrosis Factor-alpha | 2023 |
Expression of Cytokines and Neurodegeneration in the Rat Hippocampus and Cortex in the Lithium-Pilocarpine Model of Status Epilepticus and the Role of Modulation of Endocannabinoid System.
Topics: Animals; Cytokines; Disease Models, Animal; Endocannabinoids; Hippocampus; Interleukin-6; Lithium; Neocortex; Neuroinflammatory Diseases; Pilocarpine; Rats; Status Epilepticus | 2023 |
Alterations in the Properties of the Rat Hippocampus Glutamatergic System in the Lithium-Pilocarpine Model of Temporal Lobe Epilepsy.
Topics: Animals; Disease Models, Animal; Epilepsy; Epilepsy, Temporal Lobe; Hippocampus; Lithium; Pilocarpine; Rats; Receptors, AMPA; Status Epilepticus | 2023 |
A Single High Dose of Flufenamic Acid in Rats does not Reduce the Damage Associated with the Rat Lithium-Pilocarpine Model of Status Epilepticus but Leads to Deleterious Outcomes.
Topics: Animals; Anti-Inflammatory Agents; Disease Models, Animal; Epilepsy; Epilepsy, Temporal Lobe; Flufenamic Acid; Fluorodeoxyglucose F18; Gliosis; Glucose; Hippocampus; Lithium; Male; Neuroinflammatory Diseases; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus | 2023 |
Dendritic reorganization in the hippocampus, anterior temporal lobe, and frontal neocortex of lithium-pilocarpine induced Status Epilepticus (SE).
Topics: Animals; Disease Models, Animal; Hippocampus; Lithium; Neocortex; Pilocarpine; Rats; Status Epilepticus; Temporal Lobe | 2023 |
Effect of U50488, a selective kappa opioid receptor agonist and levetiracetam against lithium-pilocarpine-induced status epilepticus, spontaneous convulsive seizures and related cognitive impairment.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Anticonvulsants; Disease Models, Animal; Levetiracetam; Lithium; Male; Pilocarpine; Rats; Rats, Wistar; Receptors, Opioid, kappa; Seizures; Status Epilepticus | 2023 |
The P2X7 receptor in activated microglia promotes depression- and anxiety-like behaviors in lithium -pilocarpine induced epileptic rats.
Topics: Animals; Anxiety; Depression; Lithium; Male; Microglia; Pilocarpine; Purinergic P2X Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2X7; Status Epilepticus | 2020 |
Rosiglitazone Prevents Autophagy by Regulating Nrf2-Antioxidant Response Element in a Rat Model of Lithium-pilocarpine-induced Status Epilepticus.
Topics: Animals; Antioxidant Response Elements; Autophagy; Lithium; Male; NF-E2-Related Factor 2; Oxidative Stress; Pilocarpine; Rats; Rats, Sprague-Dawley; Rosiglitazone; Status Epilepticus | 2021 |
Gastrodin alleviates seizure severity and neuronal excitotoxicities in the rat lithium-pilocarpine model of temporal lobe epilepsy via enhancing GABAergic transmission.
Topics: Animals; Anticonvulsants; Benzyl Alcohols; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; Gastrodia; Glucosides; Hippocampus; Lithium; Male; Medicine, Chinese Traditional; Neurons; Neuroprotective Agents; Pilocarpine; Rats, Sprague-Dawley; Receptors, GABA-A; Rhizome; Seizures; Status Epilepticus | 2021 |
Enriched environment ameliorates chronic temporal lobe epilepsy-induced behavioral hyperexcitability and restores synaptic plasticity in CA3-CA1 synapses in male Wistar rats.
Topics: Animals; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Calbindins; Environment; Epilepsy, Temporal Lobe; Hyperkinesis; Lithium; Male; Neuronal Plasticity; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus; Synapses; Synaptic Transmission; Synaptophysin | 2021 |
Citral Effects on the Expression Profile of
Topics: Acyclic Monoterpenes; Animals; Brain-Derived Neurotrophic Factor; Cytokines; Disease Models, Animal; Hippocampus; Lithium; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus | 2021 |
Phase-Dependent Astroglial Alterations in Li-Pilocarpine-Induced Status Epilepticus in Young Rats.
Topics: Animals; Astrocytes; Disease Models, Animal; Epilepsy, Temporal Lobe; Hippocampus; Lithium; Nerve Degeneration; Neurons; Pilocarpine; Rats, Wistar; Status Epilepticus | 2017 |
4,4'-Diisothiocyanatostilbene-2,2'-disulfonic acid attenuates spontaneous recurrent seizures and vasogenic edema following lithium-pilocarpine induced status epilepticus.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Anticonvulsants; Apoptosis; Blood-Brain Barrier; Brain Edema; Disease Models, Animal; Epilepsy, Temporal Lobe; Lithium; Male; Pilocarpine; Rats, Sprague-Dawley; Status Epilepticus | 2017 |
The role of necroptosis in status epilepticus-induced brain injury in juvenile rats.
Topics: Amygdala; Animals; Biomarkers; Brain Injuries; Cognitive Dysfunction; Lithium; Male; Necrosis; Neurons; Pilocarpine; Piriform Cortex; Random Allocation; Rats; Rats, Sprague-Dawley; Status Epilepticus | 2017 |
Involvement of nitrergic system in anticonvulsant effect of zolpidem in lithium-pilocarpine induced status epilepticus: Evaluation of iNOS and COX-2 genes expression.
Topics: Animals; Anticonvulsants; Arginine; Cyclooxygenase 2; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression Regulation, Enzymologic; Lithium; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Pilocarpine; Pyridines; Rats; Rats, Wistar; Status Epilepticus; Zolpidem | 2017 |
Antagonist targeting microRNA-146a protects against lithium-pilocarpine-induced status epilepticus in rats by nuclear factor-κB pathway.
Topics: Animals; Biomarkers; Cytokines; Gene Expression; Hippocampus; Inflammation Mediators; Lithium; Male; MicroRNAs; NF-kappa B; Pilocarpine; Rats; Signal Transduction; Status Epilepticus | 2018 |
Intravenous infusion of mesenchymal stem cells reduces epileptogenesis in a rat model of status epilepticus.
Topics: Animals; Disease Models, Animal; Glutamate Decarboxylase; Green Fluorescent Proteins; Hippocampus; Infusions, Intravenous; Lithium; Magnetic Resonance Imaging; Male; Maze Learning; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Muscarinic Agonists; Neurons; Phosphopyruvate Hydratase; Pilocarpine; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Status Epilepticus; Time Factors | 2018 |
Post-treatment with the GLP-1 analogue liraglutide alleviate chronic inflammation and mitochondrial stress induced by Status epilepticus.
Topics: Animals; Anti-Inflammatory Agents; bcl-2-Associated X Protein; Blood Glucose; Convulsants; Cytokines; Disease Models, Animal; Gene Expression Regulation; Hippocampus; Inflammation; Liraglutide; Lithium; Male; Mitochondria; Nerve Tissue Proteins; Pilocarpine; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Status Epilepticus; Time Factors | 2018 |
Folate homeostasis in epileptic rats.
Topics: Animals; Brain; CD11b Antigen; Convulsants; Disease Models, Animal; Folate Receptor 1; Folic Acid; Glial Fibrillary Acidic Protein; Hippocampus; Homeostasis; Lithium; Male; Phosphopyruvate Hydratase; Pilocarpine; Proton-Coupled Folate Transporter; Rats; Rats, Wistar; Reduced Folate Carrier Protein; RNA, Messenger; Statistics, Nonparametric; Status Epilepticus | 2018 |
Alterations in the Neurobehavioral Phenotype and ZnT3/CB-D28k Expression in the Cerebral Cortex Following Lithium-Pilocarpine-Induced Status Epilepticus: the Ameliorative Effect of Leptin.
Topics: Animals; Behavior, Animal; Cation Transport Proteins; Cerebral Cortex; Disease Models, Animal; Female; Gene Expression Regulation; Lithium; Male; Phenotype; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus | 2019 |
Inhibition of MyD88 Signaling Skews Microglia/Macrophage Polarization and Attenuates Neuronal Apoptosis in the Hippocampus After Status Epilepticus in Mice.
Topics: Animals; Apoptosis; Cell Polarity; Cytokines; Disease Models, Animal; Female; Gene Expression Regulation, Archaeal; Hippocampus; In Situ Nick-End Labeling; Lithium; Macrophages; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Myeloid Differentiation Factor 88; Neurons; Peptides; Pilocarpine; Signal Transduction; Status Epilepticus; Toll-Like Receptor 4 | 2018 |
[CHANGES IN BRAIN ELECTRICAL ACTIVITY PATTERNS IN RATS WITH DIFFERENT SUSCEPTIBILITY TO SEIZURES IN LITHIUM-PILOCARPINE MODEL OF STATUS EPILEPTICUS].
Topics: Animals; Brain; Electroencephalography; Lithium; Male; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus | 2016 |
Neuroprotective effects of levetiracetam, both alone and combined with propylparaben, in the long-term consequences induced by lithium-pilocarpine status epilepticus.
Topics: Animals; Anticonvulsants; Behavior, Animal; Disease Models, Animal; Hippocampus; Levetiracetam; Lithium; Male; Neurons; Neuroprotective Agents; Parabens; Pilocarpine; Rats, Wistar; Seizures; Status Epilepticus; Time | 2018 |
Inhibition of protease-activated receptor 1 ameliorates behavioral deficits and restores hippocampal synaptic plasticity in a rat model of status epilepticus.
Topics: Animals; Behavior, Animal; CA1 Region, Hippocampal; Disease Models, Animal; Epilepsy, Temporal Lobe; Lithium; Long-Term Potentiation; Male; Pilocarpine; Pyrroles; Quinazolines; Rats, Wistar; Receptor, PAR-1; Status Epilepticus | 2019 |
Glycyrrhizin, an HMGB1 inhibitor, exhibits neuroprotective effects in rats after lithium-pilocarpine-induced status epilepticus.
Topics: Animals; Apoptosis; Blood-Brain Barrier; Disease Models, Animal; Glycyrrhizic Acid; Hippocampus; HMGB1 Protein; Lithium; Male; Neurons; Neuroprotective Agents; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus | 2019 |
Intravenously Administered Ganaxolone Blocks Diazepam-Resistant Lithium-Pilocarpine-Induced Status Epilepticus in Rats: Comparison with Allopregnanolone.
Topics: Administration, Intravenous; Anesthetics; Animals; Anticonvulsants; Diazepam; Drug Resistant Epilepsy; Electroencephalography; Lithium; Male; Muscarinic Agonists; Pilocarpine; Pregnanolone; Rats; Rats, Sprague-Dawley; Status Epilepticus | 2019 |
The Effects of Minocycline on the Hippocampus in Lithium- Pilocarpine Induced Status Epilepticus in Rat: Relations with Microglial/Astrocytic Activation and Serum S100B Level.
Topics: Animals; Anti-Inflammatory Agents; Astrocytes; Biomarkers; Convulsants; Disease Models, Animal; Hippocampus; Lithium; Male; Microglia; Minocycline; Pilocarpine; Rats; Rats, Sprague-Dawley; S100 Calcium Binding Protein beta Subunit; Status Epilepticus | 2019 |
The effects of lamotrigine and ethosuximide on seizure frequency, neuronal loss, and astrogliosis in a model of temporal-lobe epilepsy.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; Ethosuximide; Female; Gliosis; Hippocampus; Lamotrigine; Lithium; Neurons; Neuroprotective Agents; Pilocarpine; Rats; Rats, Sprague-Dawley; Seizures; Status Epilepticus | 2019 |
Hydrogen Alleviates Necroptosis and Cognitive Deficits in Lithium-Pilocarpine Model of Status Epilepticus.
Topics: Animals; Apoptosis; CA1 Region, Hippocampal; Cognition Disorders; Disease Models, Animal; Hydrogen; Inflammation; Lithium; Male; Memory; Necrosis; Neurons; Neuroprotective Agents; Pilocarpine; Rats, Sprague-Dawley; Spatial Learning; Status Epilepticus | 2019 |
Impairments in cognitive functions and emotional and social behaviors in a rat lithium-pilocarpine model of temporal lobe epilepsy.
Topics: Animals; Anxiety; Behavior, Animal; Cognition; Emotions; Epilepsy; Epilepsy, Temporal Lobe; Exploratory Behavior; Fear; Lithium; Male; Memory Disorders; Motor Activity; Pilocarpine; Rats; Rats, Wistar; Social Behavior; Spatial Memory; Status Epilepticus | 2019 |
A comprehensive behavioral evaluation in the lithium-pilocarpine model in rats: effects of carisbamate administration during status epilepticus.
Topics: Animals; Anticonvulsants; Antipsychotic Agents; Behavior, Animal; Brain; Carbamates; Cell Count; Disease Models, Animal; Lithium; Male; Maze Learning; Memory; Mossy Fibers, Hippocampal; Muscarinic Agonists; Neurons; Phosphopyruvate Hydratase; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus; Visual Perception | 2013 |
Neuronal degeneration is observed in multiple regions outside the hippocampus after lithium pilocarpine-induced status epilepticus in the immature rat.
Topics: Animals; Brain; Convulsants; Disease Models, Animal; Hippocampus; Lithium; Nerve Degeneration; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus | 2013 |
Effect of lithium-pilocarpine-induced status epilepticus on ultrasonic vocalizations in the infant rat pup.
Topics: Age Factors; Animals; Animals, Newborn; Chi-Square Distribution; Convulsants; Disease Models, Animal; Female; Lithium; Male; Maternal Deprivation; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus; Vocalization, Animal | 2014 |
Dexamethasone exacerbates cerebral edema and brain injury following lithium-pilocarpine induced status epilepticus.
Topics: Animals; Anti-Inflammatory Agents; Brain Edema; Brain Injuries; Cerebral Cortex; Dexamethasone; Disease Models, Animal; Image Processing, Computer-Assisted; Linear Models; Lithium; Magnetic Resonance Imaging; Male; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus; Time Factors | 2014 |
Dynamics of hippocampal acetylcholine release during lithium-pilocarpine-induced status epilepticus in rats.
Topics: Acetylcholine; Animals; Extracellular Fluid; Hippocampus; Lithium; Male; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus | 2014 |
Persistent reduction of hippocampal glutamine synthetase expression after status epilepticus in immature rats.
Topics: Animals; Disease Models, Animal; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Glutamate-Ammonia Ligase; Hippocampus; Immunohistochemistry; Lithium; Male; Neurons; Parvalbumins; Pilocarpine; Rats, Wistar; Seizures; Status Epilepticus; Vesicular Glutamate Transport Protein 1 | 2014 |
Ameliorating effects of proglumide on neurobehavioral and biochemical deficits in animal model of status epilepticus.
Topics: Animals; Cognition; Disease Models, Animal; Glutathione; Lithium; Male; Motor Activity; Oxidative Stress; Pilocarpine; Proglumide; Rats; Rats, Sprague-Dawley; Status Epilepticus | 2014 |
Bumetanide is not capable of terminating status epilepticus but enhances phenobarbital efficacy in different rat models.
Topics: Animals; Anticonvulsants; Basolateral Nuclear Complex; Bumetanide; Disease Models, Animal; Drug Synergism; Electric Stimulation; Kainic Acid; Lithium; Male; Phenobarbital; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus | 2015 |
Deep hypothermia for the treatment of refractory status epilepticus.
Topics: Animals; Convulsants; Drug Resistant Epilepsy; Electroencephalography; Hypothermia, Induced; Lithium; Male; Midazolam; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus | 2015 |
Serotonin Depletion Does not Modify the Short-Term Brain Hypometabolism and Hippocampal Neurodegeneration Induced by the Lithium-Pilocarpine Model of Status Epilepticus in Rats.
Topics: Animals; Disease Models, Animal; Fenclonine; Gliosis; Hippocampus; Lithium; Magnetic Resonance Imaging; Male; Nerve Degeneration; Pilocarpine; Positron-Emission Tomography; Rats, Sprague-Dawley; Serotonin; Status Epilepticus; Time Factors | 2016 |
Bimodal Imaging of Inflammation with SPECT/CT and MRI Using Iodine-125 Labeled VCAM-1 Targeting Microparticle Conjugates.
Topics: Animals; Antibodies, Monoclonal; Brain; Contrast Media; Ferric Compounds; Image Processing, Computer-Assisted; Inflammation; Iodine Radioisotopes; Lithium; Magnetic Resonance Imaging; Male; Microspheres; Multimodal Imaging; Muscarinic Agonists; Pilocarpine; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Status Epilepticus; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; Vascular Cell Adhesion Molecule-1 | 2015 |
[Changes in CD40 expression in the pallium and hippocampus in epileptic rats].
Topics: Animals; CD40 Antigens; Epilepsy; Hippocampus; Immunohistochemistry; Lithium; Microglia; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus | 2015 |
Early metabolic responses to lithium/pilocarpine-induced status epilepticus in rat brain.
Topics: Animals; Brain; Choline; Convulsants; Disease Models, Animal; Electrochemistry; Electron Transport Chain Complex Proteins; Glucose; Lactic Acid; Lithium; Male; Microdialysis; Oxidative Stress; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus | 2015 |
Novel combinations of phenotypic biomarkers predict development of epilepsy in the lithium-pilocarpine model of temporal lobe epilepsy in rats.
Topics: Animals; Biomarkers; Brain; Electroencephalography; Epilepsy, Temporal Lobe; Female; Lithium; Male; Pentylenetetrazole; Pilocarpine; Prospective Studies; Rats; Reaction Time; ROC Curve; Seizures; Status Epilepticus | 2015 |
Status epilepticus triggers early mitochondrial fusion in the rat hippocampus in a lithium-pilocarpine model.
Topics: Animals; Blotting, Western; Dynamins; GTP Phosphohydrolases; Hippocampus; Injections, Intraperitoneal; Lithium; Male; Membrane Proteins; Microscopy, Electron, Transmission; Mitochondria; Mitochondrial Dynamics; Mitochondrial Proteins; Models, Animal; Pilocarpine; Rats; Rats, Wistar; RNA, Messenger; Status Epilepticus; Time Factors | 2016 |
Hippocampal distribution of IL-1β and IL-1RI following lithium-pilocarpine-induced status epilepticus in the developing rat.
Topics: Animals; Convulsants; Disease Models, Animal; Hippocampus; Interleukin-1beta; Lithium; Pilocarpine; Rats; Receptors, Interleukin-1; RNA, Messenger; Status Epilepticus | 2016 |
Immediate and delayed treatment with gabapentin, carbamazepine and CNQX have almost similar impact on cognitive functions and behavior in the lithium-pilocarpine model in rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amines; Animals; Behavior, Animal; Carbamazepine; Cognition; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Lithium; Male; Maze Learning; Motor Activity; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus | 2016 |
Status epilepticus alters hippocampal long-term synaptic potentiation in a rat lithium-pilocarpine model.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Convulsants; Disease Models, Animal; Hippocampus; In Vitro Techniques; Lithium; Long-Term Potentiation; Patch-Clamp Techniques; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus; Time Factors | 2016 |
The effect of some immunomodulatory and anti-inflammatory drugs on Li-pilocarpine-induced epileptic disorders in Wistar rats.
Topics: Animals; Anti-Inflammatory Agents; Dinoprostone; Electroencephalography; Encephalitis; HSP72 Heat-Shock Proteins; Immunomodulation; Interleukin-1beta; Interleukin-6; Lithium; Male; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus | 2016 |
Memantine attenuates cognitive impairments after status epilepticus induced in a lithium-pilocarpine model.
Topics: Animals; Cognition; Cognitive Dysfunction; Exploratory Behavior; Extinction, Psychological; Lithium; Male; Memantine; Orientation; Pilocarpine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spatial Memory; Status Epilepticus; Treatment Outcome | 2016 |
Diabetic hyperglycemia aggravates seizures and status epilepticus-induced hippocampal damage.
Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Biophysics; Blood Glucose; Brain Injuries; Computer Simulation; Diabetes Mellitus, Experimental; Electric Stimulation; Hippocampus; In Situ Nick-End Labeling; In Vitro Techniques; Lithium; Long-Term Potentiation; Male; Maze Learning; Models, Biological; Neurons; Pilocarpine; Rats; Rats, Sprague-Dawley; Seizures; Status Epilepticus | 2009 |
Differential expression of activating transcription factor-2 and c-Jun in the immature and adult rat hippocampus following lithium-pilocarpine induced status epilepticus.
Topics: Activating Transcription Factor 2; Animals; Antimanic Agents; Blotting, Western; Hippocampus; Immunohistochemistry; Lithium; Miotics; Pilocarpine; Proto-Oncogene Proteins c-jun; Rats; Status Epilepticus | 2009 |
Drug transporters are altered in brain, liver and kidney of rats with chronic epilepsy induced by lithium-pilocarpine.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Choroid Plexus; Chronic Disease; Endothelial Cells; Epilepsy; Female; Kidney; Lithium; Liver; Male; Organic Anion Transporters; Pilocarpine; Rats; Rats, Wistar; RNA, Messenger; Status Epilepticus | 2010 |
Seizures increase cell proliferation in the dentate gyrus by shortening progenitor cell-cycle length.
Topics: Animals; Animals, Newborn; Cell Cycle; Cell Proliferation; Dentate Gyrus; Hippocampus; Humans; Immunohistochemistry; Lithium; Neurons; Pilocarpine; Status Epilepticus; Stem Cells | 2009 |
Molecular basis of self-sustaining seizures and pharmacoresistance during status epilepticus: The receptor trafficking hypothesis revisited.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Drug Resistance; Epilepsy; Hippocampus; Humans; Immunohistochemistry; Lithium; Models, Neurological; Pilocarpine; Rats; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Status Epilepticus; Synapses | 2009 |
Quantitative MRI predicts status epilepticus-induced hippocampal injury in the lithium-pilocarpine rat model.
Topics: Analysis of Variance; Animals; Brain Mapping; Cell Count; Cell Death; Cerebrovascular Circulation; Hippocampus; Image Processing, Computer-Assisted; Lithium; Magnetic Resonance Imaging; Male; Organ Size; Parietal Lobe; Pilocarpine; Predictive Value of Tests; Rats; Rats, Sprague-Dawley; Status Epilepticus; Thalamus; Time Factors | 2010 |
Prevention of seizures and reorganization of hippocampal functions by transplantation of bone marrow cells in the acute phase of experimental epilepsy.
Topics: Analysis of Variance; Animals; Antigens, CD; Bone Marrow Transplantation; Cell Movement; Disease Models, Animal; Electric Stimulation; Excitatory Postsynaptic Potentials; Flow Cytometry; Glial Fibrillary Acidic Protein; Green Fluorescent Proteins; Hippocampus; In Vitro Techniques; Lithium; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Patch-Clamp Techniques; Pilocarpine; Rats; Rats, Wistar; Seizures; Status Epilepticus; Time Factors | 2010 |
Oxidative stress mediates hippocampal neuron death in rats after lithium-pilocarpine-induced status epilepticus.
Topics: Animals; Blotting, Western; Caspase 3; Cell Death; Hippocampus; Immunohistochemistry; Immunosuppressive Agents; Lithium; Male; Malondialdehyde; Neurons; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Oxidative Stress; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus; Tacrolimus | 2010 |
Time-dependent changes in learning ability and induction of long-term potentiation in the lithium-pilocarpine-induced epileptic mouse model.
Topics: Animals; Biophysics; Conditioning, Classical; Disease Models, Animal; Electric Stimulation; Excitatory Postsynaptic Potentials; Fear; GABA Antagonists; Hippocampus; In Vitro Techniques; Learning Disabilities; Lithium; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; Patch-Clamp Techniques; Picrotoxin; Pilocarpine; Status Epilepticus; Time Factors | 2010 |
Granulocyte colony-stimulating factor treatment prevents cognitive impairment following status epilepticus in rats.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cognition Disorders; Granulocyte Colony-Stimulating Factor; Hippocampus; Humans; In Situ Nick-End Labeling; Lithium; Male; Maze Learning; Neuroprotective Agents; Phosphorylation; Pilocarpine; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Status Epilepticus | 2010 |
Effect of ketogenic diet on nucleotide hydrolysis and hepatic enzymes in blood serum of rats in a lithium-pilocarpine-induced status epilepticus.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Convulsants; Diet, Ketogenic; Disease Models, Animal; Enzymes; Female; Hydrolysis; Lithium; Liver; Nucleotides; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus | 2010 |
Expression profile of microRNAs in rat hippocampus following lithium-pilocarpine-induced status epilepticus.
Topics: Animals; Convulsants; Gene Expression Profiling; Hippocampus; Lithium; Male; MicroRNAs; Oligonucleotide Array Sequence Analysis; Pilocarpine; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Status Epilepticus | 2011 |
Neuroprotective effects of recombinant human erythropoietin in the developing brain of rat after lithium-pilocarpine induced status epilepticus.
Topics: Animals; Apoptosis; Convulsants; Erythropoietin; Hippocampus; Humans; In Situ Nick-End Labeling; Lithium; Male; Neurons; Neuroprotective Agents; Pilocarpine; Rats; Rats, Wistar; Recombinant Proteins; Status Epilepticus | 2012 |
Functional network changes in hippocampal CA1 after status epilepticus predict spatial memory deficits in rats.
Topics: Animals; CA1 Region, Hippocampal; Disease Models, Animal; Electrodes, Implanted; Entropy; Image Processing, Computer-Assisted; Lithium; Male; Maze Learning; Memory Disorders; Models, Neurological; Muscarinic Agonists; Nerve Net; Neurons; Pilocarpine; Predictive Value of Tests; Probability; Rats; Rats, Sprague-Dawley; Space Perception; Statistics as Topic; Statistics, Nonparametric; Status Epilepticus | 2012 |
TGFβ1 treatment reduces hippocampal damage, spontaneous recurrent seizures, and learning memory deficits in pilocarpine-treated rats.
Topics: Administration, Intranasal; Animals; Apoptosis; Hippocampus; Lithium; Male; Maze Learning; Memory Disorders; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus; Transforming Growth Factor beta1 | 2013 |
MicroRNA expression profile of the hippocampus in a rat model of temporal lobe epilepsy and miR-34a-targeted neuroprotection against hippocampal neurone cell apoptosis post-status epilepticus.
Topics: Analysis of Variance; Animals; Apoptosis; Caspase 3; Cell Death; Computational Biology; Disease Models, Animal; Epilepsy, Temporal Lobe; Hippocampus; In Situ Nick-End Labeling; Lithium; Male; Microarray Analysis; MicroRNAs; Neurons; Oligonucleotides; Pilocarpine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Status Epilepticus; Up-Regulation | 2012 |
Epileptogenesis during development: injury, circuit recruitment, and plasticity.
Topics: Aging; Animals; Animals, Newborn; Convulsants; Dentate Gyrus; Electric Stimulation; Hippocampus; Immunohistochemistry; Lithium; Mossy Fibers, Hippocampal; Neural Inhibition; Neural Pathways; Neuronal Plasticity; Perforant Pathway; Phosphopyruvate Hydratase; Pilocarpine; Proto-Oncogene Proteins c-jun; Rats; Rats, Wistar; Recruitment, Neurophysiological; Status Epilepticus; Substance P | 2002 |
Status epilepticus induced by lithium-pilocarpine in the immature rat does not change the long-term susceptibility to seizures.
Topics: Aging; Animals; Animals, Newborn; Cerebellar Cortex; Disease Models, Animal; Disease Susceptibility; Dose-Response Relationship, Drug; Electroencephalography; Excitatory Amino Acid Agonists; Female; GABA Antagonists; GABA-A Receptor Antagonists; Kainic Acid; Lithium; Male; Muscarinic Agonists; Pentylenetetrazole; Picrotoxin; Pilocarpine; Rats; Rats, Sprague-Dawley; Reaction Time; Status Epilepticus | 2002 |
Nonconvulsive status epilepticus from accidental lithium ingestion.
Topics: Aged; Aged, 80 and over; Epilepsy, Generalized; Female; Humans; Lithium; Status Epilepticus | 2002 |
Lithium intoxication mimicking clinical and electrographic features of status epilepticus: a case report and review of the literature.
Topics: Electroencephalography; Female; Humans; Lithium; Middle Aged; Neurotoxicity Syndromes; Status Epilepticus | 2003 |
Detection of late epilepsy by the texture analysis of MR brain images in the lithium-pilocarpine rat model.
Topics: Animals; Cerebral Cortex; Entorhinal Cortex; Epilepsy; Image Processing, Computer-Assisted; Lithium; Magnetic Resonance Imaging; Male; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus | 2002 |
Epilepsy after early-life seizures can be independent of hippocampal injury.
Topics: Age Factors; Animals; Electroencephalography; Hippocampus; Lithium; Mossy Fibers, Hippocampal; Muscarinic Agonists; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus | 2003 |
Lithium/pilocarpine status epilepticus-induced neuropathology of piriform cortex and adjoining structures in rats is age-dependent.
Topics: Aging; Animals; Brain; Cerebral Cortex; Disease Susceptibility; Lithium; Pilocarpine; Rats; Status Epilepticus | 2003 |
Development of temporal lobe epilepsy in 21-day-old rats.
Topics: Age Factors; Animals; Brain; Disease Models, Animal; Epilepsy, Temporal Lobe; Lithium; Magnetic Resonance Imaging; Pilocarpine; Rats; Status Epilepticus | 2003 |
Long-term pregabalin treatment protects basal cortices and delays the occurrence of spontaneous seizures in the lithium-pilocarpine model in the rat.
Topics: Animals; Anticonvulsants; Astrocytes; Brain; Cell Death; Cerebral Cortex; Convulsants; Electroencephalography; Entorhinal Cortex; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Hippocampus; Immunoenzyme Techniques; Lithium; Neuroprotective Agents; Parahippocampal Gyrus; Pilocarpine; Pregabalin; Rats; Rats, Sprague-Dawley; Status Epilepticus | 2003 |
Diazepam terminates brief but not prolonged seizures in young, naïve rats.
Topics: Age Factors; Animals; Anticonvulsants; Cerebral Cortex; Diazepam; Dose-Response Relationship, Drug; Drug Administration Schedule; Electroencephalography; Epilepsy, Generalized; Lithium; Male; Pilocarpine; Rats; Receptors, GABA-A; Status Epilepticus; Treatment Outcome | 2003 |
Effect of the postictal state on visual-spatial memory in immature rats.
Topics: Animals; Animals, Newborn; Behavior, Animal; Caffeine; Central Nervous System Stimulants; Convulsants; Electroencephalography; Flurothyl; Hippocampus; Lithium; Male; Maze Learning; Memory; Memory Disorders; Muscarinic Agonists; Pilocarpine; Rats; Rats, Sprague-Dawley; Space Perception; Staining and Labeling; Status Epilepticus; Time Factors | 2003 |
Neuroprotective properties of topiramate in the lithium-pilocarpine model of epilepsy.
Topics: Animals; Blood Gas Analysis; Cell Death; Cerebral Cortex; Electroencephalography; Fructose; Hippocampus; Hydrogen-Ion Concentration; Lithium; Male; Neurons; Neuroprotective Agents; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus; Topiramate | 2004 |
Long-term effects of early-life malnutrition and status epilepticus: assessment by spatial navigation and CREB(Serine-133) phosphorylation.
Topics: Animals; Animals, Newborn; Cell Death; Cyclic AMP Response Element-Binding Protein; Down-Regulation; Epilepsy; Hippocampus; Humans; Infant Nutrition Disorders; Infant, Newborn; Lithium; Male; Maze Learning; Memory Disorders; Mortality; Neurons; Orientation; Phosphorylation; Pilocarpine; Rats; Rats, Sprague-Dawley; Signal Transduction; Space Perception; Status Epilepticus; Time | 2003 |
Pharmacological plasticity of GABA(A) receptors at dentate gyrus synapses in a rat model of temporal lobe epilepsy.
Topics: Animals; Anticonvulsants; Dentate Gyrus; Diazepam; Disease Models, Animal; Electric Conductivity; Epilepsy, Temporal Lobe; Flumazenil; GABA Modulators; Lithium; Male; Neural Inhibition; Patch-Clamp Techniques; Pilocarpine; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Status Epilepticus; Synapses | 2004 |
Spontaneous recurrent seizure following status epilepticus enhances dentate gyrus neurogenesis.
Topics: Animals; Bromodeoxyuridine; Cell Differentiation; Cell Division; Dentate Gyrus; Disease Models, Animal; Lithium; Neuronal Plasticity; Neurons; Pilocarpine; Rats; Rats, Sprague-Dawley; Recurrence; Seizures; Status Epilepticus; Stem Cells | 2004 |
Differential neuroprotective effects of the NMDA receptor-associated glycine site partial agonists 1-aminocyclopropanecarboxylic acid (ACPC) and D-cycloserine in lithium-pilocarpine status epilepticus.
Topics: Amino Acids, Cyclic; Animals; Antimetabolites; Brain; Cycloserine; Electrodes, Implanted; Electroencephalography; Image Processing, Computer-Assisted; Lithium; Male; Motor Activity; Muscarinic Agonists; Neuroprotective Agents; Parasympathetic Nervous System; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Status Epilepticus | 2004 |
Postnatal maturation of cytochrome oxidase and lactate dehydrogenase activity and age-dependent consequences of lithium-pilocarpine status epilepticus in the rat: a regional histoenzymology study.
Topics: Age Factors; Animals; Animals, Newborn; Brain; Electron Transport Complex IV; Female; Glucose; L-Lactate Dehydrogenase; Lithium; Male; Muscarinic Agonists; Pilocarpine; Pregnancy; Rats; Rats, Sprague-Dawley; Status Epilepticus | 2004 |
In vivo 1H magnetic resonance spectroscopy, T2-weighted and diffusion-weighted MRI during lithium-pilocarpine-induced status epilepticus in the rat.
Topics: Animals; Brain; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Lithium; Male; Muscarinic Agonists; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus | 2004 |
Temporal patterns of the cerebral inflammatory response in the rat lithium-pilocarpine model of temporal lobe epilepsy.
Topics: Animals; Cyclooxygenase 2; Disease Models, Animal; Epilepsy, Temporal Lobe; Inflammation; Interleukin-1; Kinetics; Lithium; NF-kappa B; Pilocarpine; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Status Epilepticus | 2004 |
Changes in phosphorylation of the NMDA receptor in the rat hippocampus induced by status epilepticus.
Topics: Animals; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Drug Synergism; Epilepsy; Focal Adhesion Kinase 2; Hippocampus; Lithium; Male; Muscarinic Agonists; Neurons; Phosphorylation; Pilocarpine; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Serine; src-Family Kinases; Status Epilepticus; Tyrosine | 2005 |
Comparison of neuroprotective effects induced by alpha-phenyl-N-tert-butyl nitrone (PBN) and N-tert-butyl-alpha-(2 sulfophenyl) nitrone (S-PBN) in lithium-pilocarpine status epilepticus.
Topics: Animals; Benzenesulfonates; Brain; Cyclic N-Oxides; Disease Models, Animal; Electroencephalography; Free Radical Scavengers; Lithium; Male; Neuroprotective Agents; Nitrogen Oxides; Pilocarpine; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Status Epilepticus | 2005 |
Effect of neonatal isolation on outcome following neonatal seizures in rats--the role of corticosterone.
Topics: Animals; Animals, Newborn; Behavior, Animal; Convulsants; Corticosterone; Cyclic AMP Response Element-Binding Protein; Enzyme Inhibitors; Hippocampus; Hypothalamo-Hypophyseal System; Kindling, Neurologic; Lithium; Male; Maternal Deprivation; Maze Learning; Metyrapone; Phosphorylation; Pilocarpine; Pituitary-Adrenal System; Random Allocation; Rats; Rats, Sprague-Dawley; Social Isolation; Spatial Behavior; Status Epilepticus | 2006 |
Increase in tyrosine phosphorylation of the NMDA receptor following the induction of status epilepticus.
Topics: Animals; Blotting, Western; Disease Models, Animal; Enzyme Activation; Focal Adhesion Kinase 2; Guanine Nucleotide Exchange Factors; Hippocampus; Lithium; Male; Phosphorylation; Pilocarpine; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; src-Family Kinases; Status Epilepticus; Time Factors; Tyrosine | 2006 |
Non-convulsive status epilepticus during lithium treatment at therapeutic doses.
Topics: Bipolar Disorder; Electroencephalography; Female; Humans; Lithium; Magnetic Resonance Imaging; Middle Aged; Status Epilepticus | 2006 |
Effects of uridine in models of epileptogenesis and seizures.
Topics: Animals; Anticonvulsants; Behavior, Animal; Disease Models, Animal; Electroencephalography; Hippocampus; Kindling, Neurologic; Lithium; Male; Maze Learning; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus; Uridine; Water | 2006 |
Status epilepticus differentially alters AMPA and kainate receptor subunit expression in mature and immature dentate granule neurons.
Topics: Animals; Animals, Newborn; Blotting, Northern; Blotting, Western; Dentate Gyrus; Disease Models, Animal; Gene Expression Regulation, Developmental; Immunohistochemistry; Lithium; Neural Cell Adhesion Molecule L1; Neurons; Phosphopyruvate Hydratase; Pilocarpine; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Reverse Transcriptase Polymerase Chain Reaction; Sialic Acids; Status Epilepticus | 2006 |
The combination of topiramate and diazepam is partially neuroprotective in the hippocampus but not antiepileptogenic in the lithium-pilocarpine model of temporal lobe epilepsy.
Topics: Animals; Anticonvulsants; Diazepam; Disease Models, Animal; Drug Therapy, Combination; Electroencephalography; Epilepsy, Temporal Lobe; Fructose; Hippocampus; Lithium; Magnetic Resonance Imaging; Male; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus; Topiramate | 2006 |
Increased GABA(A)-receptor alpha1-subunit expression in hippocampal dentate gyrus after early-life status epilepticus.
Topics: Animals; Animals, Newborn; Dentate Gyrus; Gene Expression; Hippocampus; Kainic Acid; Lithium; Nucleic Acid Amplification Techniques; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Status Epilepticus | 2006 |
Dissociation of the immunoreactivity of synaptophysin and GAP-43 during the acute and latent phases of the lithium-pilocarpine model in the immature and adult rat.
Topics: Age Factors; Animals; Animals, Newborn; Behavior, Animal; Brain; Disease Models, Animal; GAP-43 Protein; Gene Expression Regulation, Developmental; Immunohistochemistry; Lithium; Male; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus; Synaptophysin; Time Factors | 2007 |
Proteome changes associated with hippocampal MRI abnormalities in the lithium pilocarpine-induced model of convulsive status epilepticus.
Topics: Animals; Disease Models, Animal; Electrophoresis, Gel, Two-Dimensional; Hippocampus; Humans; Lithium; Magnetic Resonance Imaging; Male; Mass Spectrometry; Muscarinic Agonists; Pilocarpine; Proteome; Rats; Rats, Sprague-Dawley; Status Epilepticus | 2007 |
Lithium overdose causing non-convulsive status epilepticus--the importance of lithium levels and the electroencephalography in diagnosis.
Topics: Drug Overdose; Electroencephalography; Female; Humans; Lithium; Lithium Compounds; Middle Aged; Status Epilepticus; Sulfates | 2007 |
Pentoxifylline ameliorates lithium-pilocarpine induced status epilepticus in young rats.
Topics: Animals; Animals, Newborn; Behavior, Animal; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Female; Functional Laterality; Glutathione; Hippocampus; Lithium; Male; Maze Learning; Motor Activity; Neurons; Pentoxifylline; Phosphodiesterase Inhibitors; Pilocarpine; Rats; Rats, Sprague-Dawley; Rotarod Performance Test; Serotonin; Status Epilepticus; Thiobarbituric Acid Reactive Substances | 2008 |
Alterations of GABA A-receptor function and allosteric modulation during development of status epilepticus.
Topics: Allosteric Regulation; Animals; Anticonvulsants; Benzodiazepines; Diazepam; Disease Models, Animal; Hippocampus; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Lithium; Male; Neurons; Patch-Clamp Techniques; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, GABA; Status Epilepticus; Zinc | 2008 |
Activation of cerebral peroxisome proliferator-activated receptors gamma exerts neuroprotection by inhibiting oxidative stress following pilocarpine-induced status epilepticus.
Topics: Animals; Benzamides; Cell Death; Convulsants; Disease Models, Animal; Glutathione; Heme Oxygenase (Decyclizing); Hippocampus; Lipid Peroxidation; Lithium; Male; Muscarinic Agonists; Nerve Degeneration; Neuroprotective Agents; Oxidative Stress; Pilocarpine; PPAR gamma; Pyridines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Rosiglitazone; Status Epilepticus; Superoxide Dismutase; Superoxide Dismutase-1; Thiazolidinediones | 2008 |
Mu-calpain mediates hippocampal neuron death in rats after lithium-pilocarpine-induced status epilepticus.
Topics: Animals; Antipsychotic Agents; Apoptosis Inducing Factor; BH3 Interacting Domain Death Agonist Protein; Calpain; Cell Death; Cysteine Proteinase Inhibitors; Cytochromes c; Dipeptides; Hippocampus; Humans; Lithium; Male; Muscarinic Agonists; Neurons; Pilocarpine; Random Allocation; Rats; Rats, Wistar; Spectrin; Status Epilepticus | 2008 |
The extracellular matrix protein SC1/hevin localizes to excitatory synapses following status epilepticus in the rat lithium-pilocarpine seizure model.
Topics: Animals; Blotting, Western; Brain; Calcium-Binding Proteins; Extracellular Matrix Proteins; Image Processing, Computer-Assisted; Immunohistochemistry; Lithium; Microscopy, Confocal; Microscopy, Immunoelectron; Muscarinic Agonists; Pilocarpine; Rats; Seizures; Status Epilepticus; Synapses | 2008 |
Prolonged confusional state and EEG seizure activity following concurrent ECT and lithium use.
Topics: Adult; Affective Disorders, Psychotic; Cognition Disorders; Confusion; Electroconvulsive Therapy; Electroencephalography; Female; Humans; Lithium; Seizures; Status Epilepticus | 1980 |
Preferential neuronal loss in layer III of the medial entorhinal cortex in rat models of temporal lobe epilepsy.
Topics: Animals; Behavior, Animal; Cell Death; Electric Stimulation; Entorhinal Cortex; Epilepsy, Temporal Lobe; Kainic Acid; Lithium; Male; Neurons; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus | 1995 |
Functional mapping of the early stages of status epilepticus: a 14C-2-deoxyglucose study in the lithium-pilocarpine model in rat.
Topics: Animals; Autoradiography; Brain; Carbon Radioisotopes; Deoxyglucose; Disease Models, Animal; Electroencephalography; Lithium; Male; Pilocarpine; Rats; Rats, Sprague-Dawley; Seizures; Status Epilepticus | 1995 |
Functional mapping of the late stages of status epilepticus in the lithium-pilocarpine model in rat: a 14C-2-deoxyglucose study.
Topics: Animals; Brain Mapping; Carbon Radioisotopes; Deoxyglucose; Electroencephalography; Lithium; Male; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus | 1995 |
The competitive NMDA receptor antagonist CGP 40116 protects against status epilepticus-induced neuronal damage.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Behavior, Animal; Brain; Diazepam; Electroencephalography; Lithium; Male; Neurons; Phenobarbital; Pilocarpine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Status Epilepticus | 1994 |
Extreme hypothermia induced by a synergism of acute limbic seizures, physical restraint, and acepromazine: implications for survival following brain injury.
Topics: Acepromazine; Animals; Body Temperature Regulation; Brain Injuries; Chlorides; Hypothermia; Limbic System; Lithium; Lithium Chloride; Male; Neurons; Pilocarpine; Rats; Restraint, Physical; Seizures; Status Epilepticus | 1993 |
ECT-induced status.
Topics: Adult; Diazepam; Electroconvulsive Therapy; Electroencephalography; Female; Humans; Lithium; Status Epilepticus | 1993 |
GABA metabolism in the substantia nigra, cortex, and hippocampus during status epilepticus.
Topics: Amino Acids; Aminocaproates; Animals; Cerebral Cortex; gamma-Aminobutyric Acid; Hippocampus; Lithium; Male; Parietal Lobe; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus; Substantia Nigra; Vigabatrin | 1993 |
Effects of felbamate and other anticonvulsant drugs in two models of status epilepticus in the rat.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy; Felbamate; Lithium; Male; Phenylcarbamates; Pilocarpine; Propylene Glycols; Rats; Rats, Sprague-Dawley; Seizures; Status Epilepticus | 1993 |
Induction of astroglial gene expression by experimental seizures in the rat: spatio-temporal patterns of the early stages.
Topics: Animals; Astrocytes; Behavior, Animal; Brain; Brain Chemistry; Convulsants; Excitatory Amino Acid Agonists; Gene Expression; Glial Fibrillary Acidic Protein; In Situ Hybridization; Injections, Intraventricular; Kainic Acid; Lithium; Male; Pilocarpine; Rats; Rats, Wistar; RNA, Messenger; Status Epilepticus; Time Factors | 1996 |
GABA metabolism during status epilepticus in the developing rat brain.
Topics: Age Factors; Animals; gamma-Aminobutyric Acid; Hippocampus; Lithium; Muscarinic Agonists; Parietal Lobe; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus | 1997 |
Reduced cortical ecto-ATPase activity in rat brains during prolonged status epilepticus induced by sequential administration of lithium and pilocarpine.
Topics: Adenosine Triphosphatases; Analysis of Variance; Animals; Cerebral Cortex; Chronic Disease; Drug Administration Schedule; Lithium; Male; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus; Synaptosomes | 1997 |
Modulation of lithium-pilocarpine-induced status epilepticus by adenosinergic agents.
Topics: 2-Chloroadenosine; Adenosine; Animals; Anticonvulsants; Carbamazepine; Dipyridamole; Disease Models, Animal; Dose-Response Relationship, Drug; Lithium; Male; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus; Theophylline; Vasodilator Agents | 1997 |
Inhibitory action of a calcium channel blocker (nimodipine) on seizures and brain damage induced by pilocarpine and lithium-pilocarpine in rats.
Topics: Animals; Atropine; Brain Diseases; Lithium; Male; Nimodipine; Pilocarpine; Rats; Rats, Wistar; Seizures; Status Epilepticus | 1997 |
Dopaminergic modulation of lithium/pilocarpine-induced status epilepticus in rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Azepines; Benzazepines; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Haloperidol; Lipid Peroxidation; Lithium; Male; Muscarinic Agonists; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus; Sulpiride | 1997 |
Spatial and temporal evolution of neuronal activation, stress and injury in lithium-pilocarpine seizures in adult rats.
Topics: Animals; Behavior, Animal; Brain Injuries; Electroencephalography; Lithium; Male; Neurons; Pilocarpine; Rats; Rats, Sprague-Dawley; Seizures; Status Epilepticus; Stress, Physiological; Time Factors | 1998 |
Development of self-sustaining limbic status epilepticus by continuous ventral hippocampal stimulation followed by low dose pilocarpine in rats.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Dizocilpine Maleate; Electroencephalography; Hippocampus; Limbic System; Lithium; Male; Neuroprotective Agents; Phenobarbital; Pilocarpine; Rats; Rats, Wistar; Seizures; Status Epilepticus; Stereotyped Behavior | 1998 |
Patterns of status epilepticus-induced neuronal injury during development and long-term consequences.
Topics: Age Factors; Animals; Apoptosis; Behavior, Animal; DNA; Electroencephalography; Female; In Situ Nick-End Labeling; Lithium; Male; Microscopy, Electron; Mossy Fibers, Hippocampal; Muscarinic Agonists; Neuronal Plasticity; Neurons; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus; Synapses | 1998 |
C-Fos, Jun D and HSP72 immunoreactivity, and neuronal injury following lithium-pilocarpine induced status epilepticus in immature and adult rats.
Topics: Age Factors; Animals; Brain Stem; Cerebral Cortex; Female; Heat-Shock Proteins; Hippocampus; HSP72 Heat-Shock Proteins; Lithium; Male; Mesencephalon; Muscarinic Agonists; Nerve Degeneration; Neurons; Pilocarpine; Pregnancy; Prosencephalon; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; Silver Staining; Status Epilepticus; Thalamus | 1998 |
Correlation between hypermetabolism and neuronal damage during status epilepticus induced by lithium and pilocarpine in immature and adult rats.
Topics: Aging; Animals; Animals, Newborn; Behavior, Animal; Brain; Glucose; Lactic Acid; Lithium; Male; Nerve Degeneration; Neurons; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus | 1999 |
Lithium-pilocarpine-induced status epilepticus produces necrotic neurons with internucleosomal DNA fragmentation in adult rats.
Topics: Age Factors; Animals; Apoptosis; Cell Nucleolus; Dentate Gyrus; DNA Fragmentation; In Situ Nick-End Labeling; Lithium; Male; Muscarinic Agonists; Necrosis; Neurons; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus | 1999 |
Altered residual ATP content in rat brain cortex subcellular fractions following status epilepticus induced by lithium and pilocarpine.
Topics: Adenosine Triphosphate; Animals; Cell Fractionation; Cell Membrane; Cerebral Cortex; Cytosol; Hydrolysis; Lithium; Male; Matched-Pair Analysis; Mitochondria; Phosphates; Pilocarpine; Proton-Translocating ATPases; Rats; Rats, Sprague-Dawley; Status Epilepticus; Synaptosomes; Time Factors | 1998 |
Lithium plus pilocarpine induced status epilepticus--biochemical changes.
Topics: Animals; Brain; Female; Lithium; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus | 2000 |
Electroshocks delay seizures and subsequent epileptogenesis but do not prevent neuronal damage in the lithium-pilocarpine model of epilepsy.
Topics: Animals; Anticonvulsants; Brain; Diazepam; Down-Regulation; Electrophysiology; Electroshock; Immunohistochemistry; Lithium; Male; Mossy Fibers, Hippocampal; Muscarinic Agonists; Neurons; Pilocarpine; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Seizures; Status Epilepticus | 2000 |
Seizure-induced neuronal necrosis: implications for programmed cell death mechanisms.
Topics: Animals; Apoptosis; Brain; Cell Nucleolus; Coloring Agents; DNA Damage; In Situ Nick-End Labeling; Kainic Acid; Lithium; Male; Necrosis; Neurons; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus | 2000 |
A metabolic and neuropathological approach to the understanding of plastic changes that occur in the immature and adult rat brain during lithium-pilocarpine-induced epileptogenesis.
Topics: Age Factors; Animals; Brain; Female; Glucose; Lithium; Male; Nerve Degeneration; Neuronal Plasticity; Neurons; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus | 2000 |
Granule cell neurogenesis after status epilepticus in the immature rat brain.
Topics: Animals; Brain; Cell Division; Dentate Gyrus; Electric Stimulation; Hippocampus; Injections, Intraperitoneal; Lithium; Mossy Fibers, Hippocampal; Neuronal Plasticity; Perforant Pathway; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus | 2000 |
The lesional and epileptogenic consequences of lithium-pilocarpine-induced status epilepticus are affected by previous exposure to isolated seizures: effects of amygdala kindling and maximal electroshocks.
Topics: Amygdala; Animals; Disease Models, Animal; Electroencephalography; Electroshock; Kindling, Neurologic; Lithium; Male; Muscarinic Agonists; Nerve Degeneration; Pilocarpine; Rats; Rats, Wistar; Seizures; Status Epilepticus | 2000 |
Temporal changes in neuronal dropout following inductions of lithium/pilocarpine seizures in the rat.
Topics: Animals; Brain; Cell Survival; Lithium; Male; Muscarinic Agonists; Neurons; Pilocarpine; Rats; Rats, Wistar; Seizures; Status Epilepticus | 2000 |
Effects of L-arginine on prevention and treatment of lithium-pilocarpine-induced status epilepticus.
Topics: Animals; Arginine; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy, Temporal Lobe; Lithium; Male; Muscarinic Agonists; Nitric Oxide; Pilocarpine; Rats; Rats, Wistar; Seizures; Status Epilepticus; Survival Rate | 2000 |
Nonconvulsive status epilepticus in rats: impaired responsiveness to exteroceptive stimuli.
Topics: Animals; Behavior, Animal; Brain; Disease Models, Animal; Electroencephalography; Epilepsia Partialis Continua; Epilepsy, Complex Partial; Lithium; Male; Maze Learning; Motor Cortex; Muscarinic Agonists; Pilocarpine; Postural Balance; Random Allocation; Rats; Rats, Wistar; Social Behavior; Status Epilepticus | 2000 |
Relationship between neuronal loss and interictal glucose metabolism during the chronic phase of the lithium-pilocarpine model of epilepsy in the immature and adult rat.
Topics: Action Potentials; Age Factors; Animals; Behavior, Animal; Cell Count; Chronic Disease; Dentate Gyrus; Disease Models, Animal; Electroencephalography; Entorhinal Cortex; Epilepsy, Temporal Lobe; Glucose; Lithium; Male; Neurons; Pilocarpine; Prosencephalon; Rats; Rats, Sprague-Dawley; Seizures; Status Epilepticus; Thalamus | 2001 |
Lithium does not synergize the peripheral action of cholinomimetics as seen in the central nervous system.
Topics: Acetylcholine; Animals; Blood Pressure; Brain; Cholinergic Agents; Dose-Response Relationship, Drug; Drug Synergism; Female; Guinea Pigs; Ileum; Lithium; Male; Muscle Contraction; Muscle, Smooth; Peripheral Nerves; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus | 2001 |
Repeated low-dose treatment of rats with pilocarpine: low mortality but high proportion of rats developing epilepsy.
Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Epilepsy, Temporal Lobe; Female; Lithium; Muscarinic Agonists; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus | 2001 |
Caspase inhibitors increase short-term survival of progenitor-cell progeny in the adult rat dentate gyrus following status epilepticus.
Topics: Animals; Antimetabolites; Bromodeoxyuridine; Caspase Inhibitors; Cell Count; Cell Survival; Convulsants; Dentate Gyrus; Enzyme Inhibitors; Glial Fibrillary Acidic Protein; Immunohistochemistry; In Situ Nick-End Labeling; Injections, Intraventricular; Lithium; Male; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus; Stem Cells; Tissue Fixation | 2001 |
Lithium-pilocarpine-induced status epilepticus in immature rats result in long-term deficits in spatial learning and hippocampal cell loss.
Topics: Aging; Animals; Disease Models, Animal; Epilepsy, Temporal Lobe; Female; Hippocampus; Lithium; Male; Maze Learning; Memory Disorders; Motor Activity; Movement Disorders; Muscarinic Agonists; Nerve Degeneration; Neurons; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus | 2001 |
Weight gain in post-seized rats is facilitated by adding aspirin, glucose, or glucose-taurine-acetaminophen to food mush.
Topics: Acepromazine; Acetaminophen; Animals; Aspirin; Glucose; Hypothalamic Area, Lateral; Injections, Subcutaneous; Lithium; Male; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus; Taurine; Weight Gain | 2001 |
Local cerebral blood flow during lithium-pilocarpine seizures in the developing and adult rat: role of coupling between blood flow and metabolism in the genesis of neuronal damage.
Topics: Aging; Animals; Animals, Newborn; Behavior, Animal; Brain; Cerebrovascular Circulation; Drug Synergism; Female; Glucose; Lithium; Male; Neurons; Pilocarpine; Rats; Rats, Sprague-Dawley; Seizures; Status Epilepticus | 2002 |
Immunohistochemical study of p53-associated proteins in rat brain following lithium-pilocarpine status epilepticus.
Topics: Animals; Ataxia Telangiectasia Mutated Proteins; bcl-2-Associated X Protein; Carbon-Oxygen Lyases; Cell Cycle Proteins; Cell Death; DNA-(Apurinic or Apyrimidinic Site) Lyase; DNA-Binding Proteins; fas Receptor; Immunohistochemistry; Lithium; Muscarinic Agonists; Nerve Degeneration; Neurons; Nuclear Proteins; Pilocarpine; Prosencephalon; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-mdm2; Rats; Rats, Wistar; Signal Transduction; Status Epilepticus; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Ubiquitin | 2002 |
Lithium toxicity presenting as non-convulsive status epilepticus (NCSE).
Topics: Adult; Humans; Lithium; Status Epilepticus | 2001 |
Hydroethidine detection of superoxide production during the lithium-pilocarpine model of status epilepticus.
Topics: Animals; Brain; Ethidium; Lithium; Male; Phenanthridines; Pilocarpine; Rats; Rats, Wistar; Reactive Oxygen Species; Status Epilepticus; Superoxides | 2002 |
Ontogenic study of lithium-pilocarpine-induced status epilepticus in rats.
Topics: Aging; Animals; Animals, Newborn; Cerebral Cortex; Chlorides; Drug Administration Schedule; Electroencephalography; Hippocampus; Lithium; Lithium Chloride; Motor Activity; Pilocarpine; Rats; Rats, Inbred Strains; Reference Values; Status Epilepticus; Stereotyped Behavior; Time Factors | 1992 |
Transient suppression of a secondary humoral response in rats is evoked by lithium-pilocarpine-induced limbic seizures.
Topics: Adrenocorticotropic Hormone; Animals; Antibody Formation; Cyclophosphamide; Limbic System; Lithium; Male; Pilocarpine; Rats; Rats, Wistar; Serum Albumin; Status Epilepticus | 1992 |
Seizures selectively impair agonist-stimulated phosphoinositide hydrolysis without affecting protein kinase C activity in rat brain.
Topics: Animals; Brain; Disease Models, Animal; Hippocampus; Hydrolysis; In Vitro Techniques; Lithium; Male; Norepinephrine; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Pilocarpine; Protein Kinase C; Rats; Rats, Sprague-Dawley; Status Epilepticus | 1992 |
Corpus callosotomy in the lithium-pilocarpine model of seizures and status epilepticus.
Topics: Animals; Corpus Callosum; Electroencephalography; Hippocampus; Histocytochemistry; Lithium; Pilocarpine; Rats; Rats, Sprague-Dawley; Seizures; Status Epilepticus | 1992 |
A rodent model of focally evoked self-sustaining status epilepticus.
Topics: Animals; Bicuculline; Diazepam; Disease Models, Animal; Electroencephalography; Lithium; Male; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus | 1992 |
[3H]hemicholinium-3 binding in rats with status epilepticus induced by lithium chloride and pilocarpine.
Topics: Acetylcholine; Animals; Cerebral Cortex; Chlorides; Choline; Hemicholinium 3; Hippocampus; Kinetics; Lithium; Lithium Chloride; Male; Pilocarpine; Rats; Rats, Inbred Strains; Seizures; Status Epilepticus | 1991 |
Motor and electroencephalographic response of refractory experimental status epilepticus in rats to treatment with MK-801, diazepam, or MK-801 plus diazepam.
Topics: Animals; Behavior, Animal; Diazepam; Dizocilpine Maleate; Drug Interactions; Electroencephalography; Lithium; Male; Pilocarpine; Rats; Rats, Inbred Strains; Status Epilepticus | 1991 |
Brain amino acid concentration changes during status epilepticus induced by lithium and pilocarpine.
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Electroencephalography; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Lithium; Male; Pilocarpine; Rats; Rats, Inbred Strains; Status Epilepticus; Tissue Distribution | 1990 |
Anticonvulsant actions of MK-801 on the lithium-pilocarpine model of status epilepticus in rats.
Topics: Animals; Anticonvulsants; Aspartic Acid; Cerebral Cortex; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Electroencephalography; Hippocampus; Lithium; Male; N-Methylaspartate; Pilocarpine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Status Epilepticus | 1989 |
Chronic lithium treatment and status epilepticus induced by lithium and pilocarpine cause selective changes of amino acid concentrations in rat brain regions.
Topics: Amino Acids; Animals; Brain; Cerebral Cortex; Corpus Striatum; Hippocampus; Lithium; Male; Pilocarpine; Rats; Rats, Inbred Strains; Status Epilepticus; Substantia Nigra | 1989 |
Status epilepticus is produced by administration of cholinergic agonists to lithium-treated rats: comparison with kainic acid.
Topics: Animals; Arecoline; Chlorides; Dose-Response Relationship, Drug; Drug Synergism; Electroencephalography; Kainic Acid; Lithium; Lithium Chloride; Male; Physostigmine; Pilocarpine; Rats; Rats, Inbred Strains; Status Epilepticus | 1987 |
Neurochemical consequences of status epilepticus induced in rats by coadministration of lithium and pilocarpine.
Topics: Acetylcholine; Animals; Brain; Choline; Cyclic GMP; Decerebrate State; Drug Combinations; Lithium; Male; Nervous System; Osmolar Concentration; Pilocarpine; Rats; Rats, Inbred Strains; Status Epilepticus; Tissue Distribution | 1986 |
Response of status epilepticus induced by lithium and pilocarpine to treatment with diazepam.
Topics: Analysis of Variance; Animals; Diazepam; Electroencephalography; Lithium; Pilocarpine; Reaction Time; Status Epilepticus | 1988 |
Effects of drugs on the initiation and maintenance of status epilepticus induced by administration of pilocarpine to lithium-pretreated rats.
Topics: Animals; Anticonvulsants; Atropine; Diazepam; Electroencephalography; Lithium; Male; Paraldehyde; Phenylisopropyladenosine; Pilocarpine; Rats; Rats, Inbred Strains; Status Epilepticus; Theophylline | 1987 |
Acetylcholine content in rat brain is elevated by status epilepticus induced by lithium and pilocarpine.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Atropine; Brain; Choline; Lithium; Male; Pilocarpine; Rats; Rats, Inbred Strains; Status Epilepticus | 1987 |
Characterization of lithium potentiation of pilocarpine-induced status epilepticus in rats.
Topics: Animals; Atropine; Diazepam; Drug Synergism; Electroencephalography; Hemicholinium 3; Lithium; Male; Pilocarpine; Rats; Rats, Inbred Strains; Status Epilepticus | 1986 |