lithium has been researched along with Refractory Depression in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 15 (60.00) | 24.3611 |
| 2020's | 10 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Butters, K; Frye, MA; McGee, SL; Morath, BA; Price, JB; Tye, SJ; Van De Wakker, SK; Yates, CG; Yates, NJ | 1 |
| Buoli, M; Caldiroli, A; Capellazzi, M; Capuzzi, E; Clerici, M; Colmegna, F; Dakanalis, A; Marcatili, M; Mucci, F; Tagliabue, I | 1 |
| Cleare, AJ; Day, E; Geddes, JR; Kerr-Gaffney, J; Marwood, L; McAllister-Williams, RH; McKeown, L; Oprea, E; Shah, R; Taylor, RW; Tee, H; Young, AH | 1 |
| Adli, M; Akiyama, K; Akula, N; Alda, M; Amare, AT; Ardau, R; Arias, B; Aubry, J; Backlund, L; Bauer, M; Baune, BT; Bellivier, F; Benabarre, A; Bengesser, S; Bhattacharjee, AK; Biernacka, JM; Birner, A; Brichant-Petitjean, C; Cearns, M; Cervantes, P; Chen, H; Chillotti, C; Cichon, S; Clark, SR; Colom, F; Cruceanu, C; Czerski, PM; Dalkner, N; Dayer, A; Degenhardt, F; DePaulo, JR; Étain, B; Falkai, P; Forstner, AJ; Frank, J; Frisen, L; Frye, MA; Fullerton, JM; Gard, S; Garnham, JS; Goes, FS; Grigoroiu-Serbanescu, M; Grof, P; Hashimoto, R; Hauser, J; Heilbronner, U; Herms, S; Hoffmann, P; Hofmann, A; Hou, L; Hsu, YH; Jamain, S; Jiménez, E; Kahn, JP; Kassem, L; Kato, T; Kelsoe, J; Kittel-Schneider, S; Kliwicki, S; König, B; Kuo, PH; Kusumi, I; Laje, G; Landén, M; Lavebratt, C; Leboyer, M; Leckband, SG; Maj, M; Manchia, M; Martinsson, L; McCarthy, MJ; McElroy, S; McMahon, FJ; Millischer, V; Mitchell, PB; Mitjans, M; Mondimore, FM; Monteleone, P; Nievergelt, CM; Nöthen, MM; Novák, T; O'Donovan, C; Ozaki, N; Papiol, S; Pfennig, A; Pisanu, C; Potash, JB; Reif, A; Reininghaus, E; Rietschel, M; Roberts, G; Rouleau, GA; Rybakowski, JK; Schalling, M; Schofield, PR; Schubert, KO; Schulze, TG; Schweizer, BW; Severino, G; Shekhtman, T; Shilling, PD; Shimoda, K; Simhandl, C; Slaney, CM; Squassina, A; Stamm, T; Stopkova, P; Streit, F; TekolaAyele, F; Thalamuthu, A; Tortorella, A; Turecki, G; Veeh, J; Vieta, E; Witt, SH; Zandi, PP; Zompo, MD | 1 |
| Adli, M; Behr, J; Bschor, T; Buspavanich, P; Heinz, A; Hoffmann, K; Jockers-Scherübl, MC; Köhler, S; Müller-Mertel, R; Osterland, SL; Richter, C; Ricken, R; Saritas, T; Schlattmann, P; Stamm, TJ; Steinacher, B | 1 |
| Andersson, E; Boberg, J; Clements, CC; Jonsson, L; Karlsson, R; Kowalec, K; Landén, M; Lewis, CM; Lu, Y; Rück, C; Sigström, R; Song, J; Sullivan, PF; Xiong, Y | 1 |
| Endo, K; Kodama, W; Terao, I; Tsuge, T | 1 |
| Holländer, V | 1 |
| Rybakowski, J | 2 |
| Flapper, M; Kok, R; Schutter, N; van Campen, J; van Melick, E | 1 |
| Attenburrow, MJ; Cipriani, A; Cleare, AJ; Dietch, D; Geddes, J; Goldsmith, K; Holland, R; Hutchinson, J; Marwood, L; McAllister-Williams, RH; Nair, R; Pickles, A; Romeo, R; Taylor, R; Young, AH | 1 |
| Date, I; Hosomoto, K; Kameda, M; Kawauchi, S; Kidani, N; Kin, I; Kin, K; Kuwahara, K; Morimoto, J; Sasaki, T; Tomita, Y; Umakoshi, M; Yasuhara, T | 1 |
| Gudde, A; Spijker, J; van der Meij, A | 1 |
| Bauer, M; Dell'osso, L; Dencker Vansvik, E; Jørgensen, L; Kasper, S; Köhler, J; Montgomery, SA; Pitchot, W | 1 |
| Agrimi, E; Appino, MG; Barbui, C; Barichello, A; Beneduce, R; Bighelli, I; Bisoffi, G; Bisogno, A; Bortolaso, P; Boso, M; Calandra, C; Cascone, L; Cernuto, F; Cipriani, A; Corbascio, C; Gardellin, F; Gennaro, D; Girlanda, F; Hanife, B; Lintas, C; Lorusso, M; Luchetta, C; Lucii, C; Maio, F; Marsilio, A; Mattei, C; Moretti, D; Nosè, M; Occhionero, G; Papanti, D; Parise, VF; Pecile, D; Prestia, D; Purgato, M; Restaino, F; Ruberto, A; Sciarma, T; Strizzolo, S; Tamborini, S; Todarello, O; Tozzi, F; Ziero, S; Zotos, S | 1 |
| Edwards, SJ; Hamilton, V; Nherera, L; Trevor, N | 1 |
| Benedetti, F; Colombo, C; Dallaspezia, S; Locatelli, C; Poletti, S; Riccaboni, R | 1 |
| Barbas, C; Laje, G; Lorenzo, MP; Ramamoorthy, A; Silva dos Santos, M; Villaseñor, A; Wainer, IW; Zarate, C | 1 |
| Ballard, ED; Brutsche, NE; Ionescu, DF; Luckenbaugh, DA; Lundin, NB; Machado-Vieira, R; Niciu, MJ; Richards, EM; Vande Voort, JL; Xu, AJ; Zarate, CA | 1 |
| Berger, M; Braus, DF; Dahmen, N; Dreimüller, N; Engel, A; Gorbulev, S; Helmreich, I; Hiemke, C; Kaiser, AK; Kronfeld, K; Lieb, K; Schlicht, KF; Tadić, A; Tüscher, O; van Calker, D; Wachtlin, D; Wagner, S | 1 |
| Costemale-Lacoste, JF; Gaillard, R; Guilloux, JP | 1 |
| Brisbane, DS; Cherry, S; Lie, D; Spivak, V; Wysoczanski, D | 1 |
| Aasanuma, M; Doi, M; Hayashi, H; Kitamura, Y; Koyama, T; Kuwatsuka, K; Miyake, A; Miyazaki, I; Onoue, Y; Shinomiya, K | 1 |
| Jackson, WC; Jain, R | 1 |
8 review(s) available for lithium and Refractory Depression
| Article | Year |
|---|---|
Augmentative Pharmacological Strategies in Treatment-Resistant Major Depression: A Comprehensive Review.
Topics: Anticonvulsants; Antidepressive Agents; Antidepressive Agents, Second-Generation; Buspirone; Central Nervous System Stimulants; Depressive Disorder, Treatment-Resistant; Humans; Ketamine; Lithium | 2021 |
Comparative efficacy, tolerability and acceptability of intravenous racemic ketamine with intranasal esketamine, aripiprazole and lithium as augmentative treatments for treatment-resistant unipolar depression: A systematic review and network meta-analysis
Topics: Adult; Antidepressive Agents; Aripiprazole; Depression; Depressive Disorder; Depressive Disorder, Treatment-Resistant; Humans; Ketamine; Lithium; Network Meta-Analysis | 2024 |
A half-century of participant observation in psychiatry. Part III: psychopharmacology.
Topics: Antidepressive Agents; Antipsychotic Agents; Depressive Disorder, Treatment-Resistant; History, 20th Century; History, 21st Century; Humans; Lithium; Psychiatry; Psychopharmacology; Schizophrenia | 2020 |
Lithium treatment - the state of the art for 2020.
Topics: Antipsychotic Agents; Bipolar Disorder; Depressive Disorder, Treatment-Resistant; Humans; Lithium; Lithium Compounds; Mood Disorders | 2020 |
[Lithium augmentation to monoamine oxidase-inhibitors in treatment-resistant depressive disorders: case report and overview of literature].
Topics: Antidepressive Agents; Depressive Disorder, Treatment-Resistant; Drug Therapy, Combination; Female; Humans; Lithium; Male; Middle Aged; Monoamine Oxidase Inhibitors; Treatment Outcome; Young Adult | 2019 |
Lithium or an atypical antipsychotic drug in the management of treatment-resistant depression: a systematic review and economic evaluation.
Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Cost-Benefit Analysis; Databases, Bibliographic; Depressive Disorder, Treatment-Resistant; Drug Therapy, Combination; Humans; Lithium; Outcome Assessment, Health Care; Quality-Adjusted Life Years; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; United Kingdom | 2013 |
The role of GSK-3 in treatment-resistant depression and links with the pharmacological effects of lithium and ketamine: A review of the literature.
Topics: Antidepressive Agents; Depressive Disorder, Treatment-Resistant; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Humans; Ketamine; Lithium; Mood Disorders | 2016 |
[Investigation on the mechanisms for the suppression of cell proliferation in the dentate gyrus of the hippocampus in ACTH treated rats].
Topics: Adrenocorticotropic Hormone; Animals; Brain-Derived Neurotrophic Factor; Cell Proliferation; Dentate Gyrus; Depression, Chemical; Depressive Disorder, Treatment-Resistant; Disease Models, Animal; Electroconvulsive Therapy; Hippocampus; Imipramine; Lithium; Neurogenesis; Rats | 2012 |
6 trial(s) available for lithium and Refractory Depression
| Article | Year |
|---|---|
Study protocol for a randomised pragmatic trial comparing the clinical and cost effectiveness of lithium and quetiapine augmentation in treatment resistant depression (the LQD study).
Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Cost-Benefit Analysis; Depressive Disorder, Major; Depressive Disorder, Treatment-Resistant; Drug Therapy, Combination; Humans; Lithium; Quetiapine Fumarate | 2017 |
Extended-release quetiapine fumarate (quetiapine XR) monotherapy and quetiapine XR or lithium as add-on to antidepressants in patients with treatment-resistant major depressive disorder.
Topics: Adolescent; Adult; Aged; Antidepressive Agents; Antipsychotic Agents; Delayed-Action Preparations; Depressive Disorder, Major; Depressive Disorder, Treatment-Resistant; Dibenzothiazepines; Drug Therapy, Combination; Female; Humans; Lithium; Lithium Compounds; Male; Middle Aged; Psychiatric Status Rating Scales; Quetiapine Fumarate; Treatment Outcome; Young Adult | 2013 |
Effectiveness of lithium in subjects with treatment-resistant depression and suicide risk: a protocol for a randomised, independent, pragmatic, multicentre, parallel-group, superiority clinical trial.
Topics: Adult; Antidepressive Agents; Antimanic Agents; Clinical Protocols; Depressive Disorder, Treatment-Resistant; Female; Humans; Lithium; Male; Middle Aged; Research Design; Risk; Self-Injurious Behavior; Suicide; Treatment Outcome | 2013 |
A pilot study of plasma metabolomic patterns from patients treated with ketamine for bipolar depression: evidence for a response-related difference in mitochondrial networks.
Topics: Adult; Antidepressive Agents; Biomarkers, Pharmacological; Bipolar Disorder; Cross-Over Studies; Depressive Disorder, Treatment-Resistant; Drug Therapy, Combination; Female; Humans; Ketamine; Lithium; Lysophosphatidylcholines; Lysophospholipids; Male; Metabolome; Middle Aged; Pilot Projects; Valproic Acid; Young Adult | 2014 |
Lithium and Valproate Levels Do Not Correlate with Ketamine's Antidepressant Efficacy in Treatment-Resistant Bipolar Depression.
Topics: Adult; Antidepressive Agents; Bipolar Disorder; Cross-Over Studies; Depressive Disorder, Treatment-Resistant; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Ketamine; Lithium; Male; Middle Aged; Psychiatric Status Rating Scales; Treatment Outcome; Valproic Acid | 2015 |
Randomized controlled study of early medication change for non-improvers to antidepressant therapy in major depression--The EMC trial.
Topics: Adolescent; Adult; Aged; Antidepressive Agents; Antidepressive Agents, Second-Generation; Citalopram; Delayed-Action Preparations; Depressive Disorder, Treatment-Resistant; Drug Therapy, Combination; Early Medical Intervention; Female; Humans; Lithium; Male; Middle Aged; Treatment Outcome; Venlafaxine Hydrochloride; Young Adult | 2016 |
11 other study(ies) available for lithium and Refractory Depression
| Article | Year |
|---|---|
Lithium augmentation of ketamine increases insulin signaling and antidepressant-like active stress coping in a rodent model of treatment-resistant depression.
Topics: Adaptation, Psychological; Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Depression; Depressive Disorder, Treatment-Resistant; Insulin; Ketamine; Lithium; Male; Rats; Rats, Wistar; Rodentia | 2021 |
Patient perspectives of lithium and quetiapine augmentation treatment in treatment-resistant depression: A qualitative assessment.
Topics: Antidepressive Agents; Antipsychotic Agents; Depression; Depressive Disorder, Treatment-Resistant; Drug Therapy, Combination; Humans; Lithium; Quetiapine Fumarate; Treatment Outcome | 2022 |
Using polygenic scores and clinical data for bipolar disorder patient stratification and lithium response prediction: machine learning approach - CORRIGENDUM.
Topics: Bipolar Disorder; Depressive Disorder, Major; Depressive Disorder, Treatment-Resistant; Humans; Lithium; Machine Learning | 2022 |
Acute effects of lithium augmentation on the kidney in geriatric compared with non-geriatric patients with treatment-resistant depression.
Topics: Acute Kidney Injury; Aged; Cohort Studies; Depression; Depressive Disorder, Treatment-Resistant; Humans; Kidney; Lithium; Prospective Studies | 2023 |
Polygenic risk scores of lithium response and treatment resistance in major depressive disorder.
Topics: Antidepressive Agents; Depressive Disorder, Major; Depressive Disorder, Treatment-Resistant; Electroconvulsive Therapy; Humans; Lithium | 2023 |
[Reaction on 'Lithium augmentation to monoamine oxidase-inhibitors in treatment-resistant depressive disorders: case report and overview of literature'].
Topics: Depressive Disorder, Treatment-Resistant; Drug Therapy, Combination; Humans; Lithium; Monoamine Oxidase; Monoamine Oxidase Inhibitors | 2019 |
Tolerability of lithium: A naturalistic discontinuation study in older inpatients (≥60 years).
Topics: Aged; Bipolar Disorder; Depressive Disorder, Treatment-Resistant; Humans; Inpatients; Lithium; Retrospective Studies | 2021 |
Lithium counteracts depressive behavior and augments the treatment effect of selective serotonin reuptake inhibitor in treatment-resistant depressed rats.
Topics: Animals; Antidepressive Agents; Depression; Depressive Disorder, Treatment-Resistant; Disease Models, Animal; Fluoxetine; Hippocampus; Lithium; Male; Neurogenesis; Rats; Rats, Inbred WKY; Selective Serotonin Reuptake Inhibitors; Serotonin | 2019 |
Rapid treatment response of suicidal symptoms to lithium, sleep deprivation, and light therapy (chronotherapeutics) in drug-resistant bipolar depression.
Topics: Adult; Antipsychotic Agents; Bipolar Disorder; Chronotherapy; Combined Modality Therapy; Depressive Disorder, Major; Depressive Disorder, Treatment-Resistant; Drug Resistance; Female; Humans; Lithium; Male; Middle Aged; Phototherapy; Severity of Illness Index; Sleep Deprivation; Suicide Prevention; Time Factors; Treatment Outcome | 2014 |
Lithium augmentation as an alternative to maintenance electroconvulsive therapy for recurrent major depressive disorder in older adults.
Topics: Aged; Aged, 80 and over; Antidepressive Agents; Depressive Disorder, Major; Depressive Disorder, Treatment-Resistant; Drug Therapy, Combination; Electroconvulsive Therapy; Female; Humans; Lithium; Male; Treatment Outcome | 2017 |
Beyond the resistance: how novel neurobiological understandings of depression may lead to advanced treatment strategies.
Topics: Adult; Alleles; Antidepressive Agents; Brain; Coenzymes; Controlled Clinical Trials as Topic; Cytokines; Depressive Disorder, Major; Depressive Disorder, Treatment-Resistant; DNA Mutational Analysis; Drug Therapy, Combination; Genetic Predisposition to Disease; Humans; Inflammation Mediators; Lithium; Magnetic Resonance Imaging; Methylenetetrahydrofolate Reductase (NADPH2); Nerve Growth Factors; Obesity; Obesity, Abdominal; Polymorphism, Genetic; Risk Factors; Selective Serotonin Reuptake Inhibitors; Tetrahydrofolates; Waist Circumference | 2012 |