Page last updated: 2024-08-23

lithium and Disease Models, Animal

lithium has been researched along with Disease Models, Animal in 316 studies

Research

Studies (316)

TimeframeStudies, this research(%)All Research%
pre-199042 (13.29)18.7374
1990's30 (9.49)18.2507
2000's74 (23.42)29.6817
2010's132 (41.77)24.3611
2020's38 (12.03)2.80

Authors

AuthorsStudies
Arginteanu, T; Casal, ML; Klein, PS; Lau, YK; Lin, M; Peck, SH; Shore, EM; Smith, LJ; Wu, M1
Chen, Z; Gu, J; Ma, K; Niu, J; Tao, S; Wang, P; Wang, S; Wei, S; Yang, L; Ye, M; Zhang, G; Zhang, L1
Amakhin, DV; Diespirov, GP; Postnikova, TY; Soboleva, EB; Vylekzhanina, EN; Zaitsev, AV1
Antonova, IV; Dyomina, AV; Griflyuk, AV; Kovalenko, AA; Postnikova, TY; Smolensky, IV; Zaitsev, AV; Zakharova, MV1
Dehpour, AR; Ghasemi, M; Sheibani, M1
Cisternas, P; Gherardelli, C; Inestrosa, NC1
Cai, Z; Chen, G; Chen, J; Li, Q; Li, R; Ma, X; Song, X; Tian, H; Xu, Y; Yang, L; Zhang, Q; Zhou, C; Zhuo, C1
Gupta, YK; Joshi, D; Katyal, J; Kumar, H1
Briggs, CA; Kapecki, N; Peritt, A; Peterson, DA; Shim, SS; Stutzmann, GE; Wiseman, AL1
Delgado, M; Fernández de la Rosa, R; García-García, L; Gomez, F; Pozo, MÁ1
Bakhtiari, M; Ghasemi, N; Ghosouri, S; Soleimani, M1
Abdelaty, AO; Abdelrahman, AI; Aboul Ezz, HS; Ahmed, NA; Ebrahim, YM; El-Feky, AS; Elgohary, A; Elsaeed, H; Fahmy, HM; Ismail, HA; Khadrawy, YA; Mohammed, FF; Mohammed, HS; Noor, NA; Radwan, NM; Sakraan, A; Tharwat, EK1
Cumbres-Vargas, IM; Pichardo-Macías, LA; Ramírez-San Juan, E; Zamudio, SR1
Bolshakov, AP; Borisova, MA; Karan, AA; Suleymanova, EM; Volobueva, MN1
Diespirov, GP; Griflyuk, AV; Kovalenko, AA; Postnikova, TY; Zaitsev, AV1
Aguiar-Geraldo, JM; Menegas, S; Peper-Nascimento, J; Possamai-Della, T; Quevedo, J; Valvassori, SS1
Bascuñana, P; Delgado, M; García-García, L; Gomez, F; Hernández-Martín, N; Pozo, MÁ; Rosa, RF; Silván, Á1
Bekar, LK; Pacholko, AG1
Chen, C; Chen, G; Cheng, L; Fang, T; Ping, J; Sun, Y; Tian, H; Wang, L; Zhu, J; Zhuo, C1
Bei, Y; Pyle, WG; Yang, FH1
Dyomina, AV; Smolensky, IV; Zaitsev, AV1
Banerjee, J; Chandra, PS; Dixit, AB; Dubey, V; Jain, S; Pandey, S; Roy, A; Tripathi, M1
Katyal, J; Kumar Gupta, Y; Kumar, H1
Diespirov, GP; Griflyuk, AV; Kalita, AD; Postnikova, TY; Sinyak, DS; Zaitsev, AV; Zubareva, OE1
Aguiar-Geraldo, JM; Andersen, ML; Cararo, JH; Dal-Pont, GC; Menegas, S; Possamai-Della, T; Quevedo, J; Valvassori, SS; Varela, RB1
Ayala, K; Collins, L; Ettenberg, A; Fisher, MPA; Krug, JT; Mayes, MS1
Bakırtaş, M; Sancaktar, ME1
Alberch, J; Delgado-García, JM; Fernández-García, S; Giralt, A; Gruart, A; Hervé, D; Longueville, S; Sancho-Balsells, A1
Bakırtaş, M; Bayraktar, C; Sancaktar, ME1
Aral, AM; Catalin, T; Chi, D; Chun, Y; Kumta, PN; Lee, B; Mady, LJ; Roy, A; Trejo Bittar, HE; Wagner, WR; Wu, J; Yang, K; Zheng, F1
Chiu, SC; Huang, CW; Lai, MC; Liu, PY; Wu, SN; Yang, CS1
Bona, NP; de Mattos, BDS; Gamaro, GD; Pedra, NS; Recart, VM; Soares, MSP; Spanevello, R; Spohr, L; Stefanello, F; Teixeira, FC1
Chang, S; He, X; Li, H; Li, J; Wang, D; Wang, F1
Banach, E; Bukowska-Olech, E; Celichowski, P; Kołodziejski, PA; Langwiński, W; Nogowski, L; Nowakowska, J; Pawlak, J; Pruszyńska-Oszmałek, E; Rybakowski, JK; Sakrajda, K; Sassek, M; Socha, M; Szczepankiewicz, A; Szczepankiewicz, D; Twarowska-Hauser, J; Zakowicz, P1
Li, J; Li, M; Liu, L; Wang, W1
Charret, TS; Cristina Rheder Fagundes Pascoal, A; Lopes-Cendes, I; Pascoal, VDB; Pereira, MTM1
Carter, CS; Cychosz, CC; Genova, R; Hsu, Y; Huang, SC; Moreira, NN; Pak, TK; Pieper, AA; Searby, C; Sheffield, VC; Stevens, H; Taugher, RJ; Vogel, T; Wang, K; Wemmie, JA; Zhang, Q1
Baumgarten, R; Bressers, S; Damen, L; de Groot, T; Deen, PMT; Doty, R; Korstanje, R; Kraak, J1
Blomgren, K; Culmsee, C; Dolga, AM; Kogner, P; Li, T; Wickström, M; Xie, C; Xu, Y; Zhang, Y; Zhou, K; Zhu, C1
Karyakin, VB; Magazanik, LG; Vasil'ev, DS; Zaitsev, AV; Zhuravin, IA1
de Oliveira, DL; Gonçalves, CA; Hennemann, MM; Vizuete, AFK1
Lin, Z; Pan, S; Wang, Y; Xie, L; Yang, T1
Araújo, TDS; Carvalho, AF; Chaves Filho, AJM; de Lucena, DF; de Queiroz, AIG; Lima, CNC; Macedo, D; Machado, MJS; Quevedo, J; Vasconcelos, SMM1
Celani, MVB; Dos Santos, WF; Gobbo-Neto, L; Godoy, LD; Liberato, JL; Lopes, NP1
Artola, A; Chiu, CT; Chuang, DM; Cordner, ZA; Hess, EJ; Jenkins, PM; Kim, TY; Nelson, AD; Pletnikov, MM; Ross, CA; Tamashiro, KL; Wang, X; Woolums, BM; Xiong, J; Zaika, N; Zhu, S; Zuo, Y1
Cararo, JH; Carvalho, AF; Dal-Pont, GC; Gava, FF; Mina, FG; Peterle, BR; Quevedo, J; Resende, WR; Valvassori, SS; Varela, RB1
Einat, H; Stukalin, Y1
Abreu, RRES; Arumanayagam, ACS; Barichello, T; Collodel, A; Generoso, JS; Giridharan, VV; Goularte, JA; Quevedo, J; Simões, LR; Valvassori, SS1
Fukumura, S; Honmou, O; Kataoka-Sasaki, Y; Kocsis, JD; Morita, T; Nagahama, H; Nakazaki, M; Oka, S; Sakai, T; Sasaki, M; Tsutsumi, H1
de Oliveira, DL; Gonçalves, CA; Hansen, F; Leite, MC; Negri, E; Vizuete, AFK1
Feng, P; Hölscher, C; Li, DF; Tian, MJ; Wang, RF; Xue, GF; Zheng, JY1
Ben-Hur, T; Blatch, D; Ekstein, D; Eyal, S; Han, H; Inbar, D; Mann, A; Portnoy, E; Shmuel, M1
Bastos, JR; de Miranda, AS; Machado, FS; Marciano Vieira, ÉL; Moreira, FA; Perico, KM; Teixeira, AL1
Chen, SH; Jin, MF; Li, LL; Ni, H1
Fan, Z; Feng, X; Yin, S; Zhu, X1
Kuang, F; Liu, JT; Wu, SX; Zhang, H1
Asth, L; Calo', G; Gavioli, EC; Guerrini, R; Ruzza, C; Silva, AI; Silva, EF; Souza, LS; Zaveri, NT1
Bao, AM; Cao, SX; Duan, SM; Gao, TM; Geng, HY; He, HY; Hong, B; Hu, XY; Li, XM; Lian, H; Sun, P; Yang, JM; Zhang, Y1
Austin, GL; Butterfield, DA; Cuello, AC; Do Carmo, S; Foret, MK; Hall, H; Iulita, MF; Jia, DT; Malcolm, JC; Marks, AR; Wilson, EN1
Domínguez-Valentín, AE; Hernández-Moreno, A; Orozco-Suárez, S; Rocha, L; Santana-Gómez, CE; Valle-Dorado, MG1
Al Kury, LT; Bogovyk, R; Fedoriuk, M; Isaeva, E; Krishtal, O; Nikolaienko, O; Savotchenko, A; Semenikhina, M1
Gao, F; Li, YJ; Wang, L; Yang, CM; Zhang, B1
McCarthy, MJ1
Atilla, P; Aydemir, O; Barun, S; Bulduk, EB; Kiziltas, M; Kurt, G; Muftuoglu, S; Oktem, M; Turhan, T1
Chen, L; Chen, S; Hu, K; Huang, Q; Huang, X; Li, C; Ouyang, DS; Wang, X; Zeng, G; Zeng, X; Zhou, L; Zong, W1
Kim, W; Won, SY; Yoon, BJ1
Chen, Y; Sun, M; van Luijtelaar, G; Wang, J; Wang, Q1
Cui, Z; Jia, L; Qu, Z; Si, P; Sun, C; Wang, W; Xie, T; Xue, Y; Zhen, J1
Ascoli, BM; Bristot, G; Géa, LP; Kauer-Sant'Anna, M; Pfaffenseller, B; Scotton, E1
Date, I; Hosomoto, K; Kameda, M; Kawauchi, S; Kidani, N; Kin, I; Kin, K; Kuwahara, K; Morimoto, J; Sasaki, T; Tomita, Y; Umakoshi, M; Yasuhara, T1
Baharvand, H; Fardmanesh, M; Ghaneezabadi, M; Jaberi, R; Kiani, S; Mirsadeghi, S; Mohammadshirazi, A; Naghdabadi, Z; Sadrosadat, H; Zareikheirabadi, M1
Bai, Y; Cheng, J; Liu, H; Tao, J; Xiao, Q; Zhao, Q; Zhu, Y1
Gao, F; Jia, N; Jia, R; Jiang, W; Jiang, Y; Li, R; Liu, Z; Wang, L; Wu, S; Yang, F; Zhang, H; Zhang, S; Zhang, Z; Zhao, J1
Gilkes, DM; Wirtz, D1
Dworkin, LD; Flickinger, B; Ge, Y; Gong, R; Jiang, C; Liu, Z; Lu, M; Malhotra, DK; Qiao, Y; Wang, P1
Huang, AC; Huang, CL; Wang, CC; Wang, EN; Wang, YC1
Akimana, G; Carneiro, JE; Cassel, JC; Cosquer, B; Faure, JB; Ferrandon, A; Geiger, K; Koning, E; Nehlig, A; Penazzi, L1
Chen, H; Cheng, L; Hu, J; Jiang, L; Kong, M; Li, T; Xiong, J; Ye, Y1
Chiu, CT; Chuang, DM; Leeds, P; Tanaka, M; Wang, Z; Yu, F; Zhang, Y1
Dudek, FE; Ekstrand, JJ; Scholl, EA1
Barupal, DK; Crespo-Barreto, J; Fiehn, O; Gatchel, JR; Jafar-Nejad, P; Kaddurah-Daouk, R; Perroud, B; Wang, L; Wikoff, WR; Zoghbi, HY1
Banderó, CR; Bankstahl, M; Beltrame, L; Frigerio, F; Löscher, W; Marchini, S; Noe, FM; Polascheck, N; Ravizza, T; Vezzani, A1
Jope, RS; King, MK1
Cardoso, MR; Ferreira, GK; Furlanetto, CB; Gonçalves, CL; Jeremias, IC; Quevedo, J; Resende, WR; Rezin, GT; Scaini, G; Streck, EL; Valvassori, SS; Varela, RB1
Breman, AM; Chen, H; Cheung, SW; Han, K; Hao, S; Holder, JL; Kang, H; Lu, H; Lu, HC; Patel, A; Schaaf, CP; Sun, H; Tang, J; Wu, Z; Yu, P; Zoghbi, HY1
Beltrán-Parrazal, L; López-Meraz, ML; Manzo, J; Medel-Matus, JS; Morgado-Valle, C; Pérez-Estudillo, C1
Chun, KP; Duffy, BA; Lythgoe, MF; Ma, D; Scott, RC1
Bao, H; Dworkin, L; Ge, Y; Gong, R; Peng, A; Wang, Z; Zhuang, S1
Bartoń, H; Cwynar, M; Grodzicki, T; Stompór, T1
Hasebe, S; Ogita, K; Shiba, T; Umeda, K; Yamaguchi, T; Yoneyama, M1
Gondo, Y; Hida, A; Iwayama, Y; Mishima, K; Murata, T; Ohba, H; Ohnishi, T; Watanabe, A; Yoshikawa, T1
Firouzjaei, MA; Ganjkhani, M; Hemadi, M; Kazemi, M; Moayeri, A; Nejatbakhsh, R; Shokri, S1
Chen, S; Hu, X; Song, L; Wang, J; Yan, R; Zhang, W; Zhao, S1
Altenhofen, S; Bonan, CD; Eltz, NS; Fonseca, R; Freitas, VM; Guerra, HN; Hackman, C; Nery, LR; Vianna, MR1
Dehpour, AR; Ghahremani, MH; Mehr, SE; Ostad, SN; Rahimi, HR; Razmi, A; Sharifzadeh, M1
Bos, IW; de Graan, PN; Hessel, EV; Mulder, SD; van der Hel, WS; van Eijsden, P; Verlinde, SA1
Ahmad, M; Wadaan, MA1
Gonçalves, CL; Lopes-Borges, J; Quevedo, J; Streck, EL; Tonin, PT; Valvassori, SS; Varela, RB; Vieira, JS1
Brandt, C; Erker, T; Löscher, W; Töllner, K1
Andersen, JK; Batir, S; Chinta, SJ; Dewey, CM; Kim, YH; Lieu, CA; Rajagopalan, S; Rane, A1
Löscher, W1
Hu, J; Jiang, X; Li, Y; Song, D; Wang, X; Zhu, S1
Fuentes, JM; Gómez-Sánchez, R; González-Polo, RA; Pedro, JM; Pizarro-Estrella, E; Rodríguez-Arribas, M; Yakhine-Diop, SM1
Bascuñana, P; de Cristóbal, J; Delgado, M; Fernández de la Rosa, R; García-García, L; Pozo, MA; Shiha, AA1
Alberi, L; Albrecht, U; Brai, E; Rainer, G; Ranc, V; Ripperger, JA; Sandrelli, F; Schnell, A1
Chen, G; Chen, L; Deng, W; Jiang, G; Li, J; Mi, X; Wang, N; Wang, X; Wang, Z; Zhang, Y1
Hillert, MH; Imran, I; Klein, J1
Austin, EV; Glebov, K; LaPash Daniels, CM; Lewis, D; Messing, A; Paffenroth, E; Walter, J1
Azab, AN; Boyko, M; Kaplanski, J; Nassar, A; Sharon-Granit, Y; Zlotnik, A1
Bueno-Júnior, LS; Do Val Da Silva, RA; Kandratavicius, L; Leite, JP; Lopes-Aguiar, C; Wolf, DC1
Gordin, ML; Song, J; Wang, D; Yu, Z1
Andreazza, AC; Elmi, N; Isaacs-Trepanier, C; Kim, HK; Rapoport, SI1
Chen, B; Chen, S; Chen, Z; Fang, Z; Li, Z; Ni, G; Ning, Y; Qin, J; Wu, C; Zhou, J; Zhou, L1
Álvarez-Croda, DM; Beltrán-Parrazal, L; López-Meraz, ML; Martínez-Quiroz, J; Medel-Matus, JS; Puig-Lagunes, AA; Santiago-García, J1
Arent, CO; Bogo, MR; Cancelier, K; Carvalho-Silva, M; Gomes, LM; Kist, LW; Mariot, E; Mota, IT; Quevedo, J; Rebelo, J; Scaini, G; Streck, EL; Teixeira, LJ1
Asth, L; Gavioli, EC; Lobão-Soares, B; Medeiros, IU; Santos, WB; Silva, EF; Soares-Rachetti, VP; Souza, LS1
Campos, BC; da Costa, RO; de Aquino, PE; de Barros Viana, GS; de Vasconcelos, SM; do Vale, EM; Leal, LK; Neves, KR; Nogueira, BG; Xavier, CC1
Gulec Suyen, G; Isbil-Buyukcoskun, N; Kahveci, N; Ozluk, K; Sengun, E1
Dawson, HN; Fan, Q; Ghosal, K; Pimplikar, SW1
Bartesaghi, R; Bianchi, P; Ciani, E; Emili, M; Giacomini, A; Guidi, S; Stagni, F; Trazzi, S1
Kim, KK; Kryukov, KA; Magazanik, LG; Zaitsev, AV1
Akula, JD; Chen, J; Favazza, TL; Fredrick, TW; Gong, Y; He, X; Liu, CH; Morss, PC; Saba, NJ; Sun, Y; Wang, Z1
Geyer, MA; Graves, M; Kesby, JP; Markou, A; Milienne-Petiot, M; Minassian, A; Semenova, S; van Enkhuizen, J; Young, JW1
Cai, X; Chen, P; Chen, Z; Ge, J; Hu, H; Li, F; Tian, S; Wu, N; Xu, L; Yang, Y; Yu, K; Zhang, J; Zhuang, J1
De-Paula, VJ; Forlenza, OV; Gattaz, WF1
Cai, Y; Cui, L; Li, K; Liu, T; Liu, Z; Tao, H; Wang, Y; Xing, H; Yin, M; Zhao, B; Zhao, J; Zhong, W; Zhou, H; Zhou, X1
Caballero, B; Camins, A; Casadesus, G; Ferrer, I; Folch, J; Gutierrez-Cuesta, J; Pallás, M; Smith, MA; Tajes, M1
Dill, J; Li, S; Wang, H; Zhou, F1
Dhawan, DK; Malhotra, A1
Boehrer, A; de Vasconcelos, AP; Desor, D; Nehlig, A; Raffo, E1
Bhalla, P; Chadha, VD; Dhawan, D1
Bartalucci, A; Cantafora, E; Ferrucci, M; Fornai, F; Fulceri, F; Longone, P; Nutini, M; Paparelli, A; Spalloni, A1
Allen, S; Lopez-Meraz, ML; Niquet, J; Rocha, LL; Wasterlain, CG1
Gee, A; Hosoi, R; Inoue, O; Kitano, D; Kuse, K; Momosaki, S1
Baldwin, RA; Liu, H; Mazarati, AM; Naylor, DE; Niquet, J; Suchomelova, L; Thompson, KW; Wasterlain, CG1
Carey, RM; Fournie-Zaluski, MC; Howell, NL; Kemp, BA; Padia, SH; Roques, BP1
Aviles, ER; Fujikawa, DG; Zhao, S1
Costa-Ferro, ZS; Cunha, FB; DaCosta, JC; Machado, DC; Pedroso, MF; Ribeiro-dos-Santos, R; Soares, MB; Vitola, AS; Xavier, LL1
Beurel, E; Jope, RS; King, MK; Mines, MA; Yuskaitis, CJ1
Cai, GE; Ju, G; Li, ST; Lu, QC; Yang, Q; Zhang, Y1
Kapur, J; Lawrence, C; Martin, BS; Sun, C; Williamson, J1
Battastini, AM; Bonan, CD; da Silveira, VG; de Paula Cognato, G; Figueiró, F; Müller, AP; Perry, ML1
Boku, S; Koyama, T; Nakagawa, S1
Jiang, W; Li, XW; Wang, Y; Wei, D; Zhang, SJ1
Asanuma, M; Doi, M; Gomita, Y; Kawasaki, H; Kitamura, Y; Matsunaga, H; Miyazaki, I; Nagamachi, T; Sendo, T; Shinomiya, K1
Allen, MJ; Augustin, H; Gandy, C; Hardy, J; Kerr, F; Killick, R; Lovestone, S; Partridge, L; Rogers, I; Sofola, O1
Coque, L; Dancy, EA; Dzirasa, K; Kumar, S; McClung, CA; Nicolelis, MA; Sidor, MM; Takahashi, JS1
Ding, H; Fan, Z; Ke, ZJ; Luo, J; Yong, Y1
Liang, LP; Patel, M; Waldbaum, S1
Daneshmand, A; Dehpour, AR; Fakhfouri, G; Habibollahi, P; Mehr, SE; Mohammadi, H; Rahimian, R; Talab, SS1
Gordon, RD; Pimenta, E; Stowasser, M1
Gleeson, JG; Gopal, DJ; Kim, J; Lancaster, MA; Louie, CM; Saleem, SN; Silhavy, JL; Thacker, BE; Williams, Y; Zaki, MS1
Cammarota, M; DaCosta, JC; Greggio, S; Machado, DC; Marinowic, DR; Venturin, GT; Zanirati, G1
Chiu, CT; Chuang, DM; Leeds, P; Liu, G1
Damaye, CA; He, F; Lan, Y; Peng, J; Walijee, SM; Wu, L; Yin, F; Zhang, C1
Chen, G; Fang, M; Luo, J; Peng, X; Wang, X; Xu, Y; Zhang, X; Zhang, Y; Zhao, F; Zhou, C; Zhu, Q1
Hong, E; Liy-Salmeron, G; Meneses, A; Ponce-Lopez, T1
Andersen, ML; Andreatini, R; Armani, F; Frussa-Filho, R; Galduróz, JC; Tufik, S1
Einat, H; Juetten, J1
Huang, T; Liu, ZH; Smith, CB1
Audet, JN; Julien, JP; Soucy, G1
Castro, AA; Ghisoni, K; Latini, A; Prediger, RD; Quevedo, J; Tasca, CI1
Aasanuma, M; Doi, M; Hayashi, H; Kitamura, Y; Koyama, T; Kuwatsuka, K; Miyake, A; Miyazaki, I; Onoue, Y; Shinomiya, K1
Kang, K; Kim, PY; Kim, YH; Kim, YJ; Lee, SH; Nam, JM; Roh, JN; Ryu, WS; Yoon, BW1
Brandt, C; Löscher, W; Rattka, M1
Brillaud, E; Cattaneo, E; Compte, E; Conforti, P; Ehrnhoefer, DE; Franciosi, S; Graham, RK; Hayden, MR; Maurel, JC; Néri, C; Poucheret, P; Pouladi, MA; Xie, Y; Zhang, W; Zuccato, C1
Holmes, GL; Lenck-Santini, PP; Mahoney, JM; Richard, GR; Scott, RC; Tyler, AL1
Feng, L; Hu, K; Li, Y; Long, HY; Long, LL; Ouyang, DS; Sun, DN; Xiao, B; Xie, YY; Zhang, C1
Budni, J; Dal-Pizzol, F; Deroza, PF; Fraga, Dde B; Ghedim, FV; Oliveira, MB; Quevedo, J; Steckert, AV; Valvassori, SS; Zugno, AI1
Arent, CO; Cechinel-Recco, K; de Souza, CT; Luz, G; Quevedo, J; Resende, WR; Valvassori, SS; Varela, RB; Vitto, MF1
Caldaralo, V; Ciavardelli, D; Consalvo, A; Corona, C; Di Ilio, C; Di Vacri, ML; Frazzini, V; Nisi, S; Sacchetta, P; Sensi, SL; Urbani, A1
Bedford, JJ; Davis, G; deJong, S; Gobe, G; Leader, JP; Schollum, JB; Vos, FE; Walker, RJ1
Cashman, KS; De Sarno, P; Mbana, T; McGuire, DJ; Naves, R; Raman, C; Rowse, AL1
Amit, T; Arraf, Z; Farah, R; Khamisy-Farah, R; Youdim, MB1
Karbowski, LM; Parker, GH; Persinger, MA1
Dubé, C; Koning, E; Nehlig, A1
Cha, BH; Holmes, GL; Hu, Y; Liu, X; Silveira, DC1
Persinger, MA; St-Pierre, LS1
Abbott, L; Burton, P; Fudge, ML; Mechoulam, R; Parker, LA; Schlievert, C1
Loy, R; Tariot, PN1
Gould, TD; Gray, NA; Manji, HK1
Sankar, R; Shin, D; Wasterlain, CG1
Koning, E; Leroy, C; Namer, IJ; Nehlig, A; Roch, C1
Decker, S; El-Mallakh, RS; El-Masri, MA; Huff, MO; Levy, RS; Li, XP1
Aloe, L; Angelucci, F; Mathé, AA1
Keller, AF; Leroy, C; Nehlig, A; Poisbeau, P1
Akman, C; Cha, BH; Holmes, GL; Liu, X; Silveira, DC1
Boissé, L; Heida, JG; Pittman, QJ1
McKay, BE; Persinger, MA1
Cole, RB; Ham, BM; Jacob, JT; Keese, MM1
Averbukh, M; Averbukh, Z; Berman, S; Dishy, V; Efrati, S; Feldman, L; Golik, A; Kachko, L; Weissgarten, J1
Braun, KP; de Graan, PN; Nicolay, K; Notenboom, RG; van Eijsden, P; van Nieuwenhuizen, O; Wu, O1
Ferrandon, A; Guenounou, M; Kaplan, H; Koning, E; Motte, J; Nehlig, A; Voutsinos-Porche, B1
Bissoon, N; Gurd, JW; Ikeda-Douglas, C; Milgram, NW; Moussa, R; Niimura, M1
Braunstein, E; Choi, CH; Dockendorff, TC; Ferreiro, D; Jongens, TA; Liebelt, D; McBride, SM; McDonald, TV; Nguyen, HT; Sehgal, A; Siwicki, KK; Wang, Y1
Desor, D; Detour, J; Nehlig, A; Schroeder, H1
Gould, TD; Manji, HK1
Griffith, JW; Peterson, SL; Purvis, RS1
Galic, MA; Persinger, MA1
Crema, LM; da Rocha, ER; Dalmaz, C; de Souza Wyse, AT; de Vasconcellos, AP; Dos Santos, AH; Franzon, R; Gonçalves, M; Nietto, FB; Zugno, AI1
Bradley, J; Dewhurst, S; Dou, H; Ellison, B; Gelbard, HA; Gendelman, HE; Kasiyanov, A; Maggirwar, S; Poluektova, LY; Xiong, H1
Hamamura, T; Ishihara, T; Kugo, A; Kuroda, S; Lee, VM; Nakashima, H; Oshima, E; Suguimoto, P; Terada, S; Trojanowski, JQ; Yokota, O1
Bush, AL; Hyson, RL1
Christensen, BM; Kim, YH; Kwon, TH; Nielsen, S1
Einat, H; Manji, HK1
Andreazza, AC; Ceresér, KM; Frey, BN; Kapczinski, F; Martins, MR; Quevedo, J; Réus, GZ; Valvassori, SS1
Deen, PM; Kamsteeg, EJ; Li, Y; Shaw, S; Vandewalle, A1
Ecelbarger, CA1
Dykstra, CM; Gurd, JW; Huo, JZ1
Holmes, GL; Marolewski, A; Rusche, JR; Zhao, Q1
Hall, G; Limebeer, CL; Parker, LA1
Carlezon, WA; Chu, MS; Konradi, C; Meloni, EG; Naydenov, A; Youngs, RM1
Gu, ZL; Han, R; Qin, ZH; Xu, XH; Zhang, HL1
Brooks-Kayal, AR; Cui, XN; Porter, BE1
Bolz, S; Grieb, P; Junemann, A; Lehaci, C; Mankowska, A; Rejdak, R; Schuettauf, F; Thaler, S; Zagorski, Z; Zarnowski, T; Zrenner, E1
Ferrandon, A; François, J; Koning, E; Nehlig, A1
Cox, GM; Du, P; Gelli, A; Heinrich, G; Liu, M1
Aviles, ER; Fujikawa, DG; Shinmei, SS; Zhao, S1
Boehm, N; Hanaya, R; Nehlig, A1
Einat, H; Gould, TD; Manji, HK; O'Donnell, KC; Picchini, AM; Schloesser, RJ1
Bamidele, A; Begum, S; Choy, M; de Castro, SC; Gadian, DG; Greene, ND; Leung, KY; Lythgoe, MF; Scott, RC; Wait, R1
Brown, IR; Lively, S1
Gu, ZL; Han, R; Hua, YN; Miao, YZ; Qin, ZH; Wu, JC; Xu, XH; Zhang, HL1
Almeida, OF; Longatto-Filho, A; Martins, L; Silva, R; Sousa, N1
Borghgraef, P; Croes, S; Devijver, H; Dewachter, I; Jaworski, T; Kremer, A; Muyllaert, D; Van Leuven, F1
Ahmad, M; Deeb, SA; Moutaery, KA; Tariq, M1
Bedford, JJ; Jing, R; Klein, JD; Leader, JP; Sands, JM; Walker, LJ; Walker, RJ1
Feng, HJ; Kao, C; Macdonald, RL; Mathews, GC1
Deng, YC; Huang, YG; Li, YN; Shao, XG; Sun, H; Yang, J; Yu, X1
Azzam, D; Dbaibo, G; El Dada, S; El Hokayem, J; El Sabban, M; Kobeissi, M; Koubeissi, M; Kurdi, R; Mikati, MA; Rahmeh, A; Rizk, E; Usta, J; Zeinieh, M1
Bhalla, P; Chadha, VD; Dhawan, DK1
Carvey, P; Goetz, CG; Klawans, HL1
Aubert, E; Guignard, JP1
Agarkova, VP; Alekseeva, LP; Saratikov, AS; Zamoshchina, TA1
Boedeker, B; Hickey, TM; Johnson, LF; Wilkinson, DS; Wong, RK1
Druet, P; Fillastre, JP; Méry, JP1
Abramow, M; Cogan, E1
Petty, F; Sherman, AD1
Bobkov, IuG; Ivanova, IA1
Christensen, S; Ottosen, PD1
Cabral, MA; Fernandes, G; Karniol, IG; Piedra Buena, AE; Tahim, QS1
Concannon, JT; Schechter, MD1
Jones, JB; Lange, RD1
Goldstein, MB; Halperin, ML; Schloeder, FX; Stinebaugh, BJ; Tam, SC1
Clarke, D; Doyle, AE; Hutchinson, JS; Wiley, JS1
Day, B; Friedman, SM1
Handforth, A; Treiman, DM1
Christensen, S; Hasbak, P; Shalmi, M; Søndergård, L1
Fontela, T; Ghiglione, M; Hermida, OG; Uttenthal, LO1
Alpert, C; Belmaker, RH; Bersudsky, Y; Kofman, O; Vinnitsky, I1
Diamantis, W; Gels, M; Gordon, R; Sofia, RD1
Hermini, AH; Pereira, DG; Teixeira, NA1
Boston, RC; Canolty, NL; Everts, HB; Jang, H1
George, B; Kulkarni, SK3
Fadda, P; Fratta, W; Gessa, GL; Pani, L1
Carney, SL; Gillies, AH; Ray, C1
Hull, KM; Lacouture, PG; Lewander, WJ; Linakis, JG; Lockhart, GR; Maher, TJ1
Cooper, TB; Katof, B; Levine, S; Meister, A; Saltzman, A1
Christensen, S; Hansen, AK; Marcussen, N; Shalmi, M1
Dias, EP; Figueiredo, JF; Garcia, WE; Gontijo, JR; Homsi, E1
Wasterlain, CG1
Bureau, YR; Cook, LL; Peredery, O; Persinger, MA1
Holstein-Rathlou, NH; Magyar, CE; McDonough, AA; Zhang, YB1
Antelman, SM; Austin, MC; Caggiula, AR; Edwards, DJ; Fowler, H; Gershon, S; Kiss, S; Kocan, D; Kucinski, BJ; Stiller, R1
Kajigaya, H; Tanaka, J; Yamashita, M1
George, B; Kulkarni, SK; Mathur, R1
Bourin, M; Redrobe, JP1
Lenox, RH; Manji, HK2
Boyet, S; Dubé, C; Marescaux, C; Nehlig, A2
Balbo, A; Chikhale, EG; Galdzicki, Z; Huang, W; Rapoport, SI; Schapiro, MB; van Gelderen, P1
De Montis, MG; Gambarana, C; Mangiavacchi, S; Masi, F; Scheggi, S; Tagliamonte, A; Tolu, P1
André, V; Ferrandon, A; Marescaux, C; Nehlig, A1
Güleç, G; Noyan, B1
Druga, R; Hlinák, Z; Krsek, P; Mares, P; Mikulecká, A1
Cox, LA; Kammerer, CM; Mahaney, MC; Rogers, J; Shade, RE1
Chuang, DM; Qian, Y; Qin, ZH; Senatorov, VV; Wang, Y; Wei, H; Wei, W1
Hsu, HY; Huang, LT; Lai, MC; Liou, CW; Tung, YR; Wang, TJ; Wu, CL1
Baartscheer, A; Klöpping, C; Ravesloot, JH; Schumacher, CA; van Ginneken, AC; Veldkamp, MW; Verkerk, AO1
Schrauzer, GN1
Bohuon, C; Boulu, R; Poitou, P1
Lion, JR1
Berger, FM1
Johnson, FN1
Anandam, N; Freed, EX; Lester, D; Lister, P; Riley, EP; Worsham, ED1
Klawans, HL; Nausieda, PA; Weiner, WJ1
Deftos, L; Langer, R; Lenhard, L; Pavlinac, D1
Aliev, MN; Kryzhanovskiĭ, GN1
Borzeix, MG; Cahn, J1
Burke, TJ; Conger, JD; Falk, SA; Guggenheim, SJ1
Coombes, J; Coombes, S; Parker, LA; Revusky, S1
Akiskal, HS; McKinney, WT1
Cepelová, L; Kohút, A; Nicák, A1
Frazer, A; Mendels, J1
Jope, RS; Kolasa, K; Ormandy, GC; Song, L1
Doly, M; Droy-Lefaix, MT; Jung, H; Munz, K; Remé, C; Wei, Q1
Gale, K; Pazos, A; Peterson, CJ; Vinayak, S1
Driscoll, JL; Eisenberg, MS; Lacouture, PG; Lewander, WJ; Linakis, JG; Maher, TJ; Woolf, A1
Keck, PE; McElroy, SL; Pope, HG; Seeler, DC1
Cappeliez, P; Moore, E1
Ratcliffe, F; Vale, AL1
Durkot, MJ; Francesconi, RP; Hubbard, RW; Matthew, CB1
Hilton, PJ1
Clifford, DB; Collins, RC; Maniotis, A; Olney, JW; Zorumski, CF1
Foulks, JG; Godolphin, WJ; Hansen, S; Ito, M; Kish, SJ; Perry, TL; Sutter, M; Yong, VW1
Hishida, A; Honda, N; Kumagai, H1
Mashita, K; Suzuki, K1
Davies, C; Sanger, DJ; Steinberg, H; Tomkiewicz, M; U'Prichard, DC1
Steinberg, H; Tomkiewicz, M1
Gershon, S; Geyer, H; Sanghvi, I1
Benkert, O; Hippius, H1
Dudgeon, KL; Steele, TH; Underwood, JL1
Carroll, BJ; Sharp, PT1

Reviews

28 review(s) available for lithium and Disease Models, Animal

ArticleYear
Lithium and Erectile Dysfunction: An Overview.
    Cells, 2022, 01-05, Volume: 11, Issue:1

    Topics: Animals; Disease Models, Animal; Erectile Dysfunction; Humans; Lithium; Male; Models, Biological

2022
Missing a beat: assessment of circadian rhythm abnormalities in bipolar disorder in the genomic era.
    Psychiatric genetics, 2019, Volume: 29, Issue:2

    Topics: Animals; Bipolar Disorder; Chronobiology Disorders; Circadian Rhythm; Disease Models, Animal; Genome-Wide Association Study; Genomics; Humans; Lithium; Sleep

2019
Endogenous lithium clearance: a diagnostic method of assessing sodium sensitivity in hypertension. Methodological and clinical implications.
    Kardiologia polska, 2014, Volume: 72, Issue:1

    Topics: Absorption; Animals; Disease Models, Animal; Humans; Hypertension; Kidney; Lithium; Metabolic Clearance Rate; Sodium, Dietary; Ventricular Remodeling

2014
Single versus combinatorial therapies in status epilepticus: Novel data from preclinical models.
    Epilepsy & behavior : E&B, 2015, Volume: 49

    Topics: Animals; Anticonvulsants; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Ketamine; Lithium; Phenobarbital; Pilocarpine; Rats; Seizures; Status Epilepticus

2015
Is the Modulation of Autophagy the Future in the Treatment of Neurodegenerative Diseases?
    Current topics in medicinal chemistry, 2015, Volume: 15, Issue:21

    Topics: Animals; Autophagy; Disease Models, Animal; Food; Humans; Isothiocyanates; Lithium; Neurodegenerative Diseases; Resveratrol; Sirolimus; Spermidine; Stilbenes; Sulfoxides; Trehalose; Valproic Acid

2015
Glucocorticoids and lithium in adult hippocampal neurogenesis.
    Vitamins and hormones, 2010, Volume: 82

    Topics: Animals; Antimanic Agents; Disease Models, Animal; Glucocorticoids; Hippocampus; Humans; Lithium; Mood Disorders; Neurogenesis; Rats; Stress, Psychological

2010
[Investigation on the mechanisms for the suppression of cell proliferation in the dentate gyrus of the hippocampus in ACTH treated rats].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2012, Volume: 132, Issue:2

    Topics: Adrenocorticotropic Hormone; Animals; Brain-Derived Neurotrophic Factor; Cell Proliferation; Dentate Gyrus; Depression, Chemical; Depressive Disorder, Treatment-Resistant; Disease Models, Animal; Electroconvulsive Therapy; Hippocampus; Imipramine; Lithium; Neurogenesis; Rats

2012
Neurotrophic factors and CNS disorders: findings in rodent models of depression and schizophrenia.
    Progress in brain research, 2004, Volume: 146

    Topics: Animals; Antipsychotic Agents; Brain; Brain Chemistry; Brain-Derived Neurotrophic Factor; Depression; Disease Models, Animal; Electroshock; Humans; Lithium; Nerve Growth Factor; Nerve Growth Factors; Rats; Rodentia; Schizophrenia

2004
Glycogen synthase kinase-3: a putative molecular target for lithium mimetic drugs.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2005, Volume: 30, Issue:7

    Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Circadian Rhythm; Disease Models, Animal; Electroconvulsive Therapy; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Humans; Lithium; Models, Biological; Mood Disorders; Neurotransmitter Agents; Signal Transduction; Valproic Acid

2005
Cellular plasticity cascades: genes-to-behavior pathways in animal models of bipolar disorder.
    Biological psychiatry, 2006, Jun-15, Volume: 59, Issue:12

    Topics: Animals; Antimanic Agents; Behavior, Animal; Bipolar Disorder; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Glycogen Synthase Kinases; Lithium; Mice; Neuronal Plasticity; Protein Kinase C; Proto-Oncogene Proteins c-bcl-2; Receptors, Glucocorticoid; Receptors, Glutamate; Signal Transduction; Valproic Acid

2006
Glycogen synthase kinase-3beta, or a link between amyloid and tau pathology?
    Genes, brain, and behavior, 2008, Volume: 7 Suppl 1

    Topics: Alzheimer Disease; Amyloid; Animals; Disease Models, Animal; Glycogen Synthase Kinase 3; Humans; Isoenzymes; Lithium; Mice; Mice, Transgenic; Phosphorylation; tau Proteins; Tauopathies

2008
Animal models of tardive dyskinesia: their use in the search for new treatment methods.
    Modern problems of pharmacopsychiatry, 1983, Volume: 21

    Topics: Age Factors; Amphetamine; Animals; Antipsychotic Agents; Apomorphine; Carbidopa; Corpus Striatum; Disease Models, Animal; Dopamine; Drug Combinations; Drug Interactions; Dyskinesia, Drug-Induced; Guinea Pigs; Haloperidol; Haplorhini; Humans; Levodopa; Lithium; Male; Parasympatholytics; Rats; Receptors, Dopamine; Stereotyped Behavior

1983
[Drug-induced glomerular nephropathies].
    Nephrologie, 1983, Volume: 4, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Anticonvulsants; Daunorubicin; Disease Models, Animal; Doxorubicin; Drug-Related Side Effects and Adverse Reactions; Gold; Humans; Kidney Diseases; Kidney Glomerulus; Lithium; Mercury; Mitomycin; Mitomycins; Rats; Rats, Inbred Strains; Sulfhydryl Compounds

1983
Role of lithium-ADH interaction in lithium-induced polyuria.
    Advances in nephrology from the Necker Hospital, 1984, Volume: 13

    Topics: Animals; Disease Models, Animal; Epithelium; Humans; Kidney Tubules, Collecting; Lithium; Models, Biological; Osmolar Concentration; Polyuria; Rabbits; Rats; Vasopressins

1984
Pathogenesis of distal renal tubular acidosis.
    Kidney international, 1981, Volume: 19, Issue:1

    Topics: Acidosis, Renal Tubular; Amiloride; Amphibians; Amphotericin B; Animals; Biological Transport, Active; Carbonates; Disease Models, Animal; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Kidney Tubules; Kidney Tubules, Distal; Lithium; Membrane Potentials; Rats; Turtles

1981
Lithium-pilocarpine neurotoxicity: a potential model of status epilepticus.
    Methods and findings in experimental and clinical pharmacology, 1995, Volume: 17, Issue:8

    Topics: Animals; Disease Models, Animal; Lithium; Pilocarpine; Status Epilepticus

1995
Recurrent seizures in the developing brain are harmful.
    Epilepsia, 1997, Volume: 38, Issue:6

    Topics: Adult; Animals; Brain; Brain Injuries; Child; Disease Models, Animal; Entorhinal Cortex; Epilepsy; Hippocampus; Humans; Lithium; Neural Pathways; Pilocarpine; Rats; Rats, Wistar; Recurrence; Status Epilepticus

1997
The effect of lithium administration in animal models of depression: a short review.
    Fundamental & clinical pharmacology, 1999, Volume: 13, Issue:3

    Topics: Animals; Behavior, Animal; Depression; Disease Models, Animal; Dogs; Lithium; Mice; Motor Activity; Polypharmacy; Rats

1999
Ziskind-Somerfeld Research Award. Protein kinase C signaling in the brain: molecular transduction of mood stabilization in the treatment of manic-depressive illness.
    Biological psychiatry, 1999, Nov-15, Volume: 46, Issue:10

    Topics: Animals; Antimanic Agents; Awards and Prizes; Binding, Competitive; Bipolar Disorder; Blotting, Western; Brain; Calcium-Calmodulin-Dependent Protein Kinases; Disease Models, Animal; Enzyme Activators; Glycogen Synthase Kinase 3; Humans; Lithium; Male; Protein Kinase C; Rats; Rats, Sprague-Dawley; Research; Signal Transduction; Transcription Factor AP-1; Transcription, Genetic; Valproic Acid

1999
The nature of bipolar disorder.
    The Journal of clinical psychiatry, 2000, Volume: 61 Supp 13

    Topics: Bipolar Disorder; Cell Death; Circadian Rhythm; Corticotropin-Releasing Hormone; Disease Models, Animal; Dopamine; GTP-Binding Proteins; Humans; Lithium; Neurotransmitter Agents; Norepinephrine; Phosphatidylinositols; Protein Kinase C; Serotonin; Signal Transduction; Valproic Acid

2000
Lithium: occurrence, dietary intakes, nutritional essentiality.
    Journal of the American College of Nutrition, 2002, Volume: 21, Issue:1

    Topics: Animals; Behavior; Disease Models, Animal; Female; Humans; Lithium; Male; Nutrition Policy; Nutritional Requirements; Tissue Distribution; United States; Water Supply

2002
Conceptual issues in the use of drugs for the treatment of aggression in man.
    The Journal of nervous and mental disease, 1975, Volume: 160, Issue:2-1

    Topics: Adolescent; Adult; Aggression; Alcoholic Intoxication; Animals; Anti-Anxiety Agents; Anticonvulsants; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Butyrophenones; Cannabis; Chlordiazepoxide; Disease Models, Animal; Epilepsy; Gonadal Steroid Hormones; Humans; Hyperkinesis; Impulsive Behavior; Lithium; Male; Methadone; Paranoid Disorders; Phenothiazines; Phenytoin; Psychopharmacology; Psychosurgery; Schizophrenia; Thiothixene; Violence

1975
Commentary. Depression and antidepressant drugs.
    Clinical pharmacology and therapeutics, 1975, Volume: 18, Issue:3

    Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Antidepressive Agents, Tricyclic; Depression; Disease Models, Animal; Humans; Lithium; Monoamine Oxidase Inhibitors; Serotonin; Sympathomimetics

1975
Overview of recent research in depression. Integration of ten conceptual models into a comprehensive clinical frame.
    Archives of general psychiatry, 1975, Volume: 32, Issue:3

    Topics: Anger; Animals; Anxiety, Separation; Behavior; Bipolar Disorder; Cognition; Depression; Depressive Disorder, Major; Diagnosis, Differential; Disease Models, Animal; Feedback; Happiness; Humans; Lithium; Models, Psychological; Monoamine Oxidase Inhibitors; Prognosis; Research; Self Concept; Stress, Psychological; Terminology as Topic

1975
Novel approaches to the pathophysiology of heatstroke: the energy depletion model.
    Annals of emergency medicine, 1987, Volume: 16, Issue:9

    Topics: Adaptation, Physiological; Animals; Body Temperature Regulation; Choline; Cholinergic Fibers; Disease Models, Animal; Energy Metabolism; Heat Exhaustion; Humans; Ion Channels; Lithium; Physical Endurance; Potassium; Sodium; Sweating; Vasodilation

1987
Cellular sodium transport in essential hypertension.
    The New England journal of medicine, 1986, Jan-23, Volume: 314, Issue:4

    Topics: Animals; Biological Transport; Disease Models, Animal; Drug Resistance; Erythrocytes; Humans; Hypertension; Leukocytes; Lithium; Models, Biological; Natriuretic Agents; Ouabain; Sodium; Sodium-Potassium-Exchanging ATPase

1986
[An experimental model of renal tubular acidosis--with special reference to distal renal tubular acidosis].
    Nihon rinsho. Japanese journal of clinical medicine, 1985, Volume: 43, Issue:9

    Topics: Acidosis, Renal Tubular; Aldosterone; Amiloride; Amphotericin B; Animals; Carbon Dioxide; Disease Models, Animal; Hydrogen; Hydrogen-Ion Concentration; Kidney Tubules, Distal; Lithium; Partial Pressure; Ureteral Obstruction

1985
[Goiter].
    Nihon rinsho. Japanese journal of clinical medicine, 1972, Volume: 30, Issue:1

    Topics: Aminosalicylic Acids; Animals; Antithyroid Agents; Bromides; Chickens; Deficiency Diseases; Disease Models, Animal; Fluorides; Goiter; Guinea Pigs; Humans; Iodine; Lithium; Mice; Rats; Resorcinols; Sulfonylurea Compounds; Thiocyanates; Thiourea; Thyroid Gland

1972

Other Studies

288 other study(ies) available for lithium and Disease Models, Animal

ArticleYear
Effects of lithium administration on vertebral bone disease in mucopolysaccharidosis I dogs.
    Bone, 2022, Volume: 154

    Topics: Animals; Bone Diseases; Disease Models, Animal; Dogs; Humans; Lithium; Mucopolysaccharidosis I; Thoracic Vertebrae; X-Ray Microtomography

2022
Predicting signaling pathways regulating demyelination in a rat model of lithium-pilocarpine-induced acute epilepsy: A proteomics study.
    International journal of biological macromolecules, 2021, Dec-15, Volume: 193, Issue:Pt B

    Topics: Animals; Cell Differentiation; Demyelinating Diseases; Disease Models, Animal; Epilepsy; Hippocampus; Lithium; Male; MAP Kinase Signaling System; Myelin Sheath; p38 Mitogen-Activated Protein Kinases; Pilocarpine; Proteomics; Rats; Rats, Sprague-Dawley; Signal Transduction; Thymosin

2021
Impairments of Long-Term Synaptic Plasticity in the Hippocampus of Young Rats during the Latent Phase of the Lithium-Pilocarpine Model of Temporal Lobe Epilepsy.
    International journal of molecular sciences, 2021, Dec-12, Volume: 22, Issue:24

    Topics: Animals; Disease Models, Animal; Epilepsy, Temporal Lobe; Hippocampus; Lithium; Long-Term Potentiation; Male; Pilocarpine; Rats; Rats, Wistar

2021
MTEP, a Selective mGluR5 Antagonist, Had a Neuroprotective Effect but Did Not Prevent the Development of Spontaneous Recurrent Seizures and Behavioral Comorbidities in the Rat Lithium-Pilocarpine Model of Epilepsy.
    International journal of molecular sciences, 2022, Jan-02, Volume: 23, Issue:1

    Topics: Animals; Behavior, Animal; Disease Models, Animal; Epilepsy; Hippocampus; Lithium; Male; Neurons; Neuroprotective Agents; Pilocarpine; Pyridines; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Seizures; Thiazoles

2022
Lithium Enhances Hippocampal Glucose Metabolism in an In Vitro Mice Model of Alzheimer's Disease.
    International journal of molecular sciences, 2022, Aug-05, Volume: 23, Issue:15

    Topics: Adenosine Triphosphate; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Disease Models, Animal; Glucose; Hippocampus; Lithium; Mice; Mice, Transgenic; Presenilin-1

2022
Lithium produces bi-directionally regulation of mood disturbance, acts synergistically with anti-depressive/-manic agents, and did not deteriorate the cognitive impairment in murine model of bipolar disorder.
    Translational psychiatry, 2022, 09-02, Volume: 12, Issue:1

    Topics: Animals; Anticonvulsants; Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Cognitive Dysfunction; Disease Models, Animal; Lamotrigine; Lithium; Mice; Valproic Acid

2022
Effect of morphine administration after status epilepticus on epileptogenesis in rats.
    Epilepsy & behavior : E&B, 2022, Volume: 135

    Topics: Animals; Disease Models, Animal; Epilepsy; Lithium; Morphine; Naloxone; Pilocarpine; Rats; Seizures; Status Epilepticus

2022
Lithium Provides Broad Therapeutic Benefits in an Alzheimer's Disease Mouse Model.
    Journal of Alzheimer's disease : JAD, 2023, Volume: 91, Issue:1

    Topics: Alzheimer Disease; Animals; Calcium; Disease Models, Animal; Hippocampus; Lithium; Mice; Mice, Transgenic; Nitric Oxide Synthase Type I; tau Proteins

2023
The vasodilator naftidrofuryl attenuates short-term brain glucose hypometabolism in the lithium-pilocarpine rat model of status epilepticus without providing neuroprotection.
    European journal of pharmacology, 2023, Jan-15, Volume: 939

    Topics: Animals; Brain; Disease Models, Animal; Glucose; Hippocampus; Humans; Lithium; Nafronyl; Neuroprotection; Pilocarpine; Rats; Seizures; Status Epilepticus; Vasodilator Agents

2023
Evaluation of in vivo lithium chloride effects as a GSK3-β inhibitor on human adipose derived stem cells differentiation into oligodendrocytes and re-myelination in an animal model of multiple sclerosis.
    Molecular biology reports, 2023, Volume: 50, Issue:2

    Topics: Animals; beta Catenin; Cell Differentiation; Disease Models, Animal; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Humans; Lithium; Lithium Chloride; Mice; Mice, Inbred C57BL; Multiple Sclerosis; Oligodendroglia; Stem Cells; Tolonium Chloride

2023
Evaluation of the therapeutic potential of cerebrolysin and/or lithium in the male Wistar rat model of Parkinson's disease induced by reserpine.
    Metabolic brain disease, 2023, Volume: 38, Issue:5

    Topics: Acetylcholinesterase; Animals; Disease Models, Animal; Lithium; Male; Neurodegenerative Diseases; Parkinson Disease; Rats; Rats, Wistar; Reserpine

2023
Thalidomide Attenuates Epileptogenesis and Seizures by Decreasing Brain Inflammation in Lithium Pilocarpine Rat Model.
    International journal of molecular sciences, 2023, Mar-30, Volume: 24, Issue:7

    Topics: Animals; Disease Models, Animal; Encephalitis; Epilepsy, Temporal Lobe; Hippocampus; Lithium; Male; Pilocarpine; Rats; Rats, Sprague-Dawley; Seizures; Status Epilepticus; Thalidomide; Tumor Necrosis Factor-alpha

2023
Expression of Cytokines and Neurodegeneration in the Rat Hippocampus and Cortex in the Lithium-Pilocarpine Model of Status Epilepticus and the Role of Modulation of Endocannabinoid System.
    International journal of molecular sciences, 2023, Mar-30, Volume: 24, Issue:7

    Topics: Animals; Cytokines; Disease Models, Animal; Endocannabinoids; Hippocampus; Interleukin-6; Lithium; Neocortex; Neuroinflammatory Diseases; Pilocarpine; Rats; Status Epilepticus

2023
Alterations in the Properties of the Rat Hippocampus Glutamatergic System in the Lithium-Pilocarpine Model of Temporal Lobe Epilepsy.
    Biochemistry. Biokhimiia, 2023, Volume: 88, Issue:3

    Topics: Animals; Disease Models, Animal; Epilepsy; Epilepsy, Temporal Lobe; Hippocampus; Lithium; Pilocarpine; Rats; Receptors, AMPA; Status Epilepticus

2023
Folic acid does not have an anti-manic effect but protect the brain against oxidative stress in an animal model of mania induced by ouabain.
    Journal of affective disorders, 2023, 08-01, Volume: 334

    Topics: Animals; Antimanic Agents; Behavior, Animal; Brain; Disease Models, Animal; Folic Acid; Lithium; Male; Mania; Ouabain; Oxidative Stress; Rats; Rats, Wistar

2023
A Single High Dose of Flufenamic Acid in Rats does not Reduce the Damage Associated with the Rat Lithium-Pilocarpine Model of Status Epilepticus but Leads to Deleterious Outcomes.
    Journal of integrative neuroscience, 2023, May-16, Volume: 22, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Disease Models, Animal; Epilepsy; Epilepsy, Temporal Lobe; Flufenamic Acid; Fluorodeoxyglucose F18; Gliosis; Glucose; Hippocampus; Lithium; Male; Neuroinflammatory Diseases; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus

2023
Different pharmacokinetics of lithium orotate inform why it is more potent, effective, and less toxic than lithium carbonate in a mouse model of mania.
    Journal of psychiatric research, 2023, Volume: 164

    Topics: Amphetamine; Animals; Antimanic Agents; Bipolar Disorder; Disease Models, Animal; Female; Lithium; Lithium Carbonate; Male; Mania; Mice

2023
Low-dose lithium adjunct to quetiapine improves cognitive task performance in mice with MK801-induced long-term cognitive impairment: Evidence from a pilot study.
    Journal of affective disorders, 2023, 11-01, Volume: 340

    Topics: Animals; Cognition; Cognitive Dysfunction; Disease Models, Animal; Dizocilpine Maleate; Humans; Lithium; Mice; Pilot Projects; Quetiapine Fumarate; Task Performance and Analysis

2023
Innovative Animal Models Of Cardiac Remodeling: Development And Evaluation.
    Journal of visualized experiments : JoVE, 2023, 03-03, Issue:193

    Topics: Animals; Disease Models, Animal; Heart; Heart Failure; Lithium; Swine; Swine, Miniature; Ventricular Remodeling

2023
Refinement of the Barnes and Morris water maze protocols improves characterization of spatial cognitive deficits in the lithium-pilocarpine rat model of epilepsy.
    Epilepsy & behavior : E&B, 2023, Volume: 147

    Topics: Animals; Cognition; Cognitive Dysfunction; Disease Models, Animal; Epilepsy; Epilepsy, Temporal Lobe; Lithium; Maze Learning; Morris Water Maze Test; Pilocarpine; Rats; Rats, Wistar; Spatial Learning

2023
Dendritic reorganization in the hippocampus, anterior temporal lobe, and frontal neocortex of lithium-pilocarpine induced Status Epilepticus (SE).
    Journal of chemical neuroanatomy, 2023, Volume: 133

    Topics: Animals; Disease Models, Animal; Hippocampus; Lithium; Neocortex; Pilocarpine; Rats; Status Epilepticus; Temporal Lobe

2023
Effect of U50488, a selective kappa opioid receptor agonist and levetiracetam against lithium-pilocarpine-induced status epilepticus, spontaneous convulsive seizures and related cognitive impairment.
    Neuroscience letters, 2023, 10-15, Volume: 815

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Anticonvulsants; Disease Models, Animal; Levetiracetam; Lithium; Male; Pilocarpine; Rats; Rats, Wistar; Receptors, Opioid, kappa; Seizures; Status Epilepticus

2023
Antiepileptogenic Effects of Anakinra, Lamotrigine and Their Combination in a Lithium-Pilocarpine Model of Temporal Lobe Epilepsy in Rats.
    International journal of molecular sciences, 2023, Oct-20, Volume: 24, Issue:20

    Topics: Animals; Anticonvulsants; Disease Models, Animal; Epilepsy, Temporal Lobe; Hippocampus; Interleukin 1 Receptor Antagonist Protein; Lamotrigine; Lithium; Pilocarpine; Rats; Seizures

2023
Efficacy of folic acid as an adjunct to lithium therapy on manic-like behaviors, oxidative stress and inflammatory parameters in an animal model of mania.
    Metabolic brain disease, 2020, Volume: 35, Issue:2

    Topics: Amphetamine; Animals; Antimanic Agents; Central Nervous System Stimulants; Disease Models, Animal; Drug Therapy, Combination; Folic Acid; Inflammation Mediators; Lithium; Male; Mania; Oxidative Stress; Rats; Rats, Wistar; Treatment Outcome

2020
Differential effects of lithium isotopes in a ketamine-induced hyperactivity model of mania.
    Pharmacology, biochemistry, and behavior, 2020, Volume: 190

    Topics: Animals; Antimanic Agents; Behavior, Animal; Disease Models, Animal; Isotopes; Ketamine; Lithium; Lithium Chloride; Locomotion; Male; Mania; Rats; Rats, Sprague-Dawley; Treatment Outcome

2020
A potential post-removal pH neutralization strategy to mitigate nasal button battery injuries.
    International journal of pediatric otorhinolaryngology, 2020, Volume: 133

    Topics: Acetic Acid; Animals; Cadaver; Disease Models, Animal; Electric Power Supplies; Facial Injuries; Foreign Bodies; Hydrogen-Ion Concentration; Lithium; Nasal Cartilages; Nasal Septum; Necrosis; Sheep; Temperature; Therapeutic Irrigation

2020
Astrocytic BDNF and TrkB regulate severity and neuronal activity in mouse models of temporal lobe epilepsy.
    Cell death & disease, 2020, 06-01, Volume: 11, Issue:6

    Topics: Animals; Astrocytes; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Epilepsy, Temporal Lobe; Gene Deletion; Hippocampus; Kainic Acid; Lithium; Locomotion; Mice, Inbred C57BL; Neurons; Neuroprotection; Phenotype; Pilocarpine; Receptor, trkB; Severity of Illness Index; Spatial Learning

2020
Injury Mechanism of Button Batteries in the Nasal Cavity and Possible Mitigation Strategies During Impaction.
    The Laryngoscope, 2020, Volume: 130, Issue:10

    Topics: Animals; Cadaver; Disease Models, Animal; Electric Power Supplies; Foreign Bodies; Hydrogen-Ion Concentration; Lithium; Nasal Cavity; Necrosis; Sheep

2020
In-vivo efficacy of biodegradable ultrahigh ductility Mg-Li-Zn alloy tracheal stents for pediatric airway obstruction.
    Communications biology, 2020, 12-18, Volume: 3, Issue:1

    Topics: Airway Obstruction; Alloys; Animals; Biocompatible Materials; Biopsy; Child; Disease Models, Animal; Humans; Imaging, Three-Dimensional; Immunohistochemistry; Lithium; Magnesium; Nanotechnology; Rabbits; Radiography; Stents; Tracheal Stenosis; Treatment Outcome; X-Ray Microtomography; Zinc

2020
Gastrodin alleviates seizure severity and neuronal excitotoxicities in the rat lithium-pilocarpine model of temporal lobe epilepsy via enhancing GABAergic transmission.
    Journal of ethnopharmacology, 2021, Apr-06, Volume: 269

    Topics: Animals; Anticonvulsants; Benzyl Alcohols; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; Gastrodia; Glucosides; Hippocampus; Lithium; Male; Medicine, Chinese Traditional; Neurons; Neuroprotective Agents; Pilocarpine; Rats, Sprague-Dawley; Receptors, GABA-A; Rhizome; Seizures; Status Epilepticus

2021
Gallic acid protects cerebral cortex, hippocampus, and striatum against oxidative damage and cholinergic dysfunction in an experimental model of manic-like behavior: Comparison with lithium effects.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2021, Volume: 81, Issue:2

    Topics: Animals; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Gallic Acid; Hippocampus; Lithium; Male; Mania; Motor Activity; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species

2021
Lithium alleviated spinal cord injury (SCI)-induced apoptosis and inflammation in rats via BDNF-AS/miR-9-5p axis.
    Cell and tissue research, 2021, Volume: 384, Issue:2

    Topics: Animals; Apoptosis; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Inflammation; Lithium; Male; MicroRNAs; Rats; Spinal Cord Injuries; Transfection

2021
Transcriptome Changes in Three Brain Regions during Chronic Lithium Administration in the Rat Models of Mania and Depression.
    International journal of molecular sciences, 2021, Jan-24, Volume: 22, Issue:3

    Topics: Animals; Antidepressive Agents; Antimanic Agents; Brain; Depression; Disease Models, Animal; Lithium; Male; Mania; Rats; Rats, Wistar; Transcriptome

2021
Repair of segmental bone defect using tissue engineered heterogeneous deproteinized bone doped with lithium.
    Scientific reports, 2021, 03-01, Volume: 11, Issue:1

    Topics: Animals; Bone and Bones; Bone Development; Bone Diseases; Cell Differentiation; Cell Proliferation; Disease Models, Animal; Humans; Lithium; Mesenchymal Stem Cells; Osteogenesis; Rats; RNA, Messenger; Tissue Engineering; Tissue Scaffolds; Wnt Signaling Pathway; X-Ray Microtomography

2021
Citral Effects on the Expression Profile of
    Journal of medicinal food, 2021, Volume: 24, Issue:9

    Topics: Acyclic Monoterpenes; Animals; Brain-Derived Neurotrophic Factor; Cytokines; Disease Models, Animal; Hippocampus; Lithium; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus

2021
A mouse model of Bardet-Biedl Syndrome has impaired fear memory, which is rescued by lithium treatment.
    PLoS genetics, 2021, Volume: 17, Issue:4

    Topics: Animals; Bardet-Biedl Syndrome; Cell Proliferation; Cilia; Disease Models, Animal; Fear; Hippocampus; Humans; Lithium; Memory Disorders; Mice; Microtubule-Associated Proteins; Neurogenesis; Neurons

2021
Genetic background determines renal response to chronic lithium treatment in female mice.
    Physiological genomics, 2021, 09-01, Volume: 53, Issue:9

    Topics: Animals; beta 2-Microglobulin; Biomarkers; Bipolar Disorder; Diabetes Insipidus, Nephrogenic; Disease Models, Animal; Female; Genetic Background; Immunoglobulin G; Lithium; Mice; Mice, Inbred Strains; Renal Insufficiency, Chronic

2021
Lithium protects hippocampal progenitors, cognitive performance and hypothalamus-pituitary function after irradiation to the juvenile rat brain.
    Oncotarget, 2017, May-23, Volume: 8, Issue:21

    Topics: Animals; Anxiety; Cell Line, Tumor; Cell Proliferation; Cognitive Dysfunction; Cranial Irradiation; Disease Models, Animal; Hippocampus; Humans; Hyperkinesis; Lithium; Mice; Neurogenesis; Rats; Stem Cells

2017
Early morphological and functional changes in the GABAergic system of hippocampus in the rat lithium-pilocarpine model of epilepsy.
    Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections, 2017, Volume: 472, Issue:1

    Topics: Animals; CA1 Region, Hippocampal; Disease Models, Animal; Epilepsy; GABA Plasma Membrane Transport Proteins; Glutamate Decarboxylase; Lithium; Male; Pilocarpine; Rats; Rats, Wistar

2017
Phase-Dependent Astroglial Alterations in Li-Pilocarpine-Induced Status Epilepticus in Young Rats.
    Neurochemical research, 2017, Volume: 42, Issue:10

    Topics: Animals; Astrocytes; Disease Models, Animal; Epilepsy, Temporal Lobe; Hippocampus; Lithium; Nerve Degeneration; Neurons; Pilocarpine; Rats, Wistar; Status Epilepticus

2017
4,4'-Diisothiocyanatostilbene-2,2'-disulfonic acid attenuates spontaneous recurrent seizures and vasogenic edema following lithium-pilocarpine induced status epilepticus.
    Neuroscience letters, 2017, 07-13, Volume: 653

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Anticonvulsants; Apoptosis; Blood-Brain Barrier; Brain Edema; Disease Models, Animal; Epilepsy, Temporal Lobe; Lithium; Male; Pilocarpine; Rats, Sprague-Dawley; Status Epilepticus

2017
Antimanic activity of minocycline in a GBR12909-induced model of mania in mice: Possible role of antioxidant and neurotrophic mechanisms.
    Journal of affective disorders, 2018, 01-01, Volume: 225

    Topics: Animals; Antimanic Agents; Antioxidants; Bipolar Disorder; Brain; Disease Models, Animal; Hippocampus; Lipid Peroxidation; Lithium; Male; Mice; Minocycline; Valproic Acid

2018
Disease Modifying Effects of the Spider Toxin Parawixin2 in the Experimental Epilepsy Model.
    Toxins, 2017, 08-25, Volume: 9, Issue:9

    Topics: Animals; Anticonvulsants; Disease Models, Animal; Epilepsy, Temporal Lobe; Hippocampus; Lithium; Male; Neurons; Neuroprotective Agents; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Pilocarpine; Rats, Wistar; Spider Venoms; Tiagabine; Urea

2017
Genetic disruption of ankyrin-G in adult mouse forebrain causes cortical synapse alteration and behavior reminiscent of bipolar disorder.
    Proceedings of the National Academy of Sciences of the United States of America, 2017, 09-26, Volume: 114, Issue:39

    Topics: Animals; Ankyrins; Bipolar Disorder; Disease Models, Animal; GABAergic Neurons; Lithium; Methylphenidate; Mice; Mice, Inbred C57BL; Mice, Knockout; Potassium Channels, Voltage-Gated; Prosencephalon; Proto-Oncogene Proteins c-fyn; Synapses; Valproic Acid; Voltage-Gated Sodium Channels

2017
Lithium and Tamoxifen Modulate Behavior and Protein Kinase C Activity in the Animal Model of Mania Induced by Ouabain.
    The international journal of neuropsychopharmacology, 2017, 11-01, Volume: 20, Issue:11

    Topics: Analysis of Variance; Animals; Antidepressive Agents; Bipolar Disorder; Brain; Disease Models, Animal; Drug Administration Routes; Enzyme Inhibitors; Lithium; Locomotion; Male; Ouabain; Protein Kinase C; Rats; Rats, Wistar; Tamoxifen

2017
Analyzing test batteries in animal models of psychopathology with multivariate analysis of variance (MANOVA): One possible approach to increase external validity.
    Pharmacology, biochemistry, and behavior, 2019, Volume: 178

    Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Antimanic Agents; Anxiety; Behavior Rating Scale; Behavior, Animal; Bipolar Disorder; Dibenzocycloheptenes; Disease Models, Animal; Female; Heterocyclic Compounds, 4 or More Rings; Lithium; Luria-Nebraska Neuropsychological Battery; Male; Mice; Multivariate Analysis; Psychopathology; Reproducibility of Results; Sex Factors

2019
Prevention of Memory Impairment and Neurotrophic Factors Increased by Lithium in Wistar Rats Submitted to Pneumococcal Meningitis Model.
    Mediators of inflammation, 2017, Volume: 2017

    Topics: Animals; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Glial Cell Line-Derived Neurotrophic Factor; Hippocampus; Lithium; Male; Memory Disorders; Meningitis, Pneumococcal; Neuroprotective Agents; Rats; Rats, Wistar

2017
Intravenous infusion of mesenchymal stem cells reduces epileptogenesis in a rat model of status epilepticus.
    Epilepsy research, 2018, Volume: 141

    Topics: Animals; Disease Models, Animal; Glutamate Decarboxylase; Green Fluorescent Proteins; Hippocampus; Infusions, Intravenous; Lithium; Magnetic Resonance Imaging; Male; Maze Learning; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Muscarinic Agonists; Neurons; Phosphopyruvate Hydratase; Pilocarpine; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Status Epilepticus; Time Factors

2018
Effects of dexamethasone on the Li-pilocarpine model of epilepsy: protection against hippocampal inflammation and astrogliosis.
    Journal of neuroinflammation, 2018, Mar-05, Volume: 15, Issue:1

    Topics: Analysis of Variance; Animals; Anticonvulsants; Cytokines; Dexamethasone; Dinoprostone; Disease Models, Animal; Encephalitis; Epilepsy; Glial Fibrillary Acidic Protein; Gliosis; Glutamate-Ammonia Ligase; Glutathione; Hippocampus; In Vitro Techniques; L-Lactate Dehydrogenase; Lithium; Male; Pilocarpine; Rats; Rats, Wistar; S100 Calcium Binding Protein beta Subunit

2018
Post-treatment with the GLP-1 analogue liraglutide alleviate chronic inflammation and mitochondrial stress induced by Status epilepticus.
    Epilepsy research, 2018, Volume: 142

    Topics: Animals; Anti-Inflammatory Agents; bcl-2-Associated X Protein; Blood Glucose; Convulsants; Cytokines; Disease Models, Animal; Gene Expression Regulation; Hippocampus; Inflammation; Liraglutide; Lithium; Male; Mitochondria; Nerve Tissue Proteins; Pilocarpine; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Status Epilepticus; Time Factors

2018
Folate homeostasis in epileptic rats.
    Epilepsy research, 2018, Volume: 142

    Topics: Animals; Brain; CD11b Antigen; Convulsants; Disease Models, Animal; Folate Receptor 1; Folic Acid; Glial Fibrillary Acidic Protein; Hippocampus; Homeostasis; Lithium; Male; Phosphopyruvate Hydratase; Pilocarpine; Proton-Coupled Folate Transporter; Rats; Rats, Wistar; Reduced Folate Carrier Protein; RNA, Messenger; Statistics, Nonparametric; Status Epilepticus

2018
Inhibition of the dopamine transporter as an animal model of bipolar disorder mania: Locomotor response, neuroimmunological profile and pharmacological modulation.
    Journal of psychiatric research, 2018, Volume: 102

    Topics: Animals; Antidepressive Agents; Aripiprazole; Bipolar Disorder; Brain; Cytokines; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Lithium; Locomotion; Male; Mice; Nerve Growth Factors; Piperazines; Time Factors; Valproic Acid

2018
Alterations in the Neurobehavioral Phenotype and ZnT3/CB-D28k Expression in the Cerebral Cortex Following Lithium-Pilocarpine-Induced Status Epilepticus: the Ameliorative Effect of Leptin.
    Biological trace element research, 2019, Volume: 187, Issue:1

    Topics: Animals; Behavior, Animal; Cation Transport Proteins; Cerebral Cortex; Disease Models, Animal; Female; Gene Expression Regulation; Lithium; Male; Phenotype; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus

2019
Immunotherapy by targeting of VGKC complex for seizure control and prevention of cognitive impairment in a mouse model of epilepsy.
    Molecular medicine reports, 2018, Volume: 18, Issue:1

    Topics: Animals; Antibodies; Cognitive Dysfunction; Disease Models, Animal; Humans; Immunotherapy; Lithium; Mice; Pilocarpine; Potassium Channels, Voltage-Gated; Seizures

2018
Inhibition of MyD88 Signaling Skews Microglia/Macrophage Polarization and Attenuates Neuronal Apoptosis in the Hippocampus After Status Epilepticus in Mice.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2018, Volume: 15, Issue:4

    Topics: Animals; Apoptosis; Cell Polarity; Cytokines; Disease Models, Animal; Female; Gene Expression Regulation, Archaeal; Hippocampus; In Situ Nick-End Labeling; Lithium; Macrophages; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Myeloid Differentiation Factor 88; Neurons; Peptides; Pilocarpine; Signal Transduction; Status Epilepticus; Toll-Like Receptor 4

2018
Nociceptin/orphanin FQ receptor agonists increase aggressiveness in the mouse resident-intruder test.
    Behavioural brain research, 2019, 01-01, Volume: 356

    Topics: Aggression; Agonistic Behavior; Animals; Anxiety; Bipolar Disorder; Carbamazepine; Cycloheptanes; Depression; Depressive Disorder; Disease Models, Animal; Fenclonine; Lithium; Male; Mice; Mice, Knockout; Nociceptin; Nociceptin Receptor; Opioid Peptides; Piperidines; Receptors, Opioid; Valproic Acid

2019
ErbB4 deletion in noradrenergic neurons in the locus coeruleus induces mania-like behavior via elevated catecholamines.
    eLife, 2018, 09-04, Volume: 7

    Topics: Action Potentials; Adrenergic Neurons; Animals; Behavior, Animal; Bipolar Disorder; Body Weight; Catechol O-Methyltransferase; Catecholamines; Disease Models, Animal; Dopamine; Excitatory Postsynaptic Potentials; Gene Deletion; Green Fluorescent Proteins; Integrases; Lithium; Locus Coeruleus; Mice; Norepinephrine; Phosphorylation; Receptor, ErbB-4; Receptors, N-Methyl-D-Aspartate; Tyrosine 3-Monooxygenase

2018
Microdose Lithium NP03 Diminishes Pre-Plaque Oxidative Damage and Neuroinflammation in a Rat Model of Alzheimer's-like Amyloidosis.
    Current Alzheimer research, 2018, Volume: 15, Issue:13

    Topics: Aldehydes; Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloidosis; Animals; CA1 Region, Hippocampal; Cytokines; Disease Models, Animal; Encephalitis; Humans; Lithium; Mice, Transgenic; Mutation; Plaque, Amyloid; Rats; Tyrosine

2018
Neuroprotective effects of levetiracetam, both alone and combined with propylparaben, in the long-term consequences induced by lithium-pilocarpine status epilepticus.
    Neurochemistry international, 2018, Volume: 120

    Topics: Animals; Anticonvulsants; Behavior, Animal; Disease Models, Animal; Hippocampus; Levetiracetam; Lithium; Male; Neurons; Neuroprotective Agents; Parabens; Pilocarpine; Rats, Wistar; Seizures; Status Epilepticus; Time

2018
Inhibition of protease-activated receptor 1 ameliorates behavioral deficits and restores hippocampal synaptic plasticity in a rat model of status epilepticus.
    Neuroscience letters, 2019, 01-23, Volume: 692

    Topics: Animals; Behavior, Animal; CA1 Region, Hippocampal; Disease Models, Animal; Epilepsy, Temporal Lobe; Lithium; Long-Term Potentiation; Male; Pilocarpine; Pyrroles; Quinazolines; Rats, Wistar; Receptor, PAR-1; Status Epilepticus

2019
Glycyrrhizin, an HMGB1 inhibitor, exhibits neuroprotective effects in rats after lithium-pilocarpine-induced status epilepticus.
    The Journal of pharmacy and pharmacology, 2019, Volume: 71, Issue:3

    Topics: Animals; Apoptosis; Blood-Brain Barrier; Disease Models, Animal; Glycyrrhizic Acid; Hippocampus; HMGB1 Protein; Lithium; Male; Neurons; Neuroprotective Agents; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus

2019
The Effects of Minocycline on the Hippocampus in Lithium- Pilocarpine Induced Status Epilepticus in Rat: Relations with Microglial/Astrocytic Activation and Serum S100B Level.
    Turkish neurosurgery, 2019, Volume: 29, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Astrocytes; Biomarkers; Convulsants; Disease Models, Animal; Hippocampus; Lithium; Male; Microglia; Minocycline; Pilocarpine; Rats; Rats, Sprague-Dawley; S100 Calcium Binding Protein beta Subunit; Status Epilepticus

2019
Aucubin Alleviates Seizures Activity in Li-Pilocarpine-Induced Epileptic Mice: Involvement of Inhibition of Neuroinflammation and Regulation of Neurotransmission.
    Neurochemical research, 2019, Volume: 44, Issue:2

    Topics: Animals; Astrocytes; Disease Models, Animal; Epilepsy; Hippocampus; Iridoid Glucosides; Lithium; Male; Mice; Microglia; Pilocarpine; Seizures; Synaptic Transmission

2019
CRMP2 mediates GSK3β actions in the striatum on regulating neuronal structure and mania-like behavior.
    Journal of affective disorders, 2019, 02-15, Volume: 245

    Topics: Amphetamine; Animals; Bipolar Disorder; Cells, Cultured; Corpus Striatum; Dendrites; Depression; Disease Models, Animal; Glycogen Synthase Kinase 3 beta; Humans; Lithium; Locomotion; Mice; Mice, Inbred C57BL; Mice, Knockout; Neostriatum; Neurons

2019
The effects of lamotrigine and ethosuximide on seizure frequency, neuronal loss, and astrogliosis in a model of temporal-lobe epilepsy.
    Brain research, 2019, 06-01, Volume: 1712

    Topics: Animals; Anticonvulsants; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; Ethosuximide; Female; Gliosis; Hippocampus; Lamotrigine; Lithium; Neurons; Neuroprotective Agents; Pilocarpine; Rats; Rats, Sprague-Dawley; Seizures; Status Epilepticus

2019
(-)-Epigallocatechin-3-Gallate Protects Against Lithium-Pilocarpine-Induced Epilepsy by Inhibiting the Toll-Like Receptor 4 (TLR4)/Nuclear Factor-κB (NF-κB) Signaling Pathway.
    Medical science monitor : international medical journal of experimental and clinical research, 2019, Mar-07, Volume: 25

    Topics: Animals; Catechin; Disease Models, Animal; Epilepsy; Epilepsy, Temporal Lobe; Hippocampus; Lithium; Long-Term Potentiation; Male; Neurons; Neuroprotective Agents; NF-kappa B; Pilocarpine; Rats; Rats, Sprague-Dawley; Seizures; Signal Transduction; Toll-Like Receptor 4

2019
Effects of lithium on inflammatory and neurotrophic factors after an immune challenge in a lisdexamfetamine animal model of mania.
    Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999), 2019, Volume: 41, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Bipolar Disorder; Brain-Derived Neurotrophic Factor; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Lipopolysaccharides; Lisdexamfetamine Dimesylate; Lithium; Locomotion; Male; Nerve Growth Factors; Nitric Oxide Synthase Type II; Rats, Wistar; Reproducibility of Results; Time Factors; Treatment Outcome

2019
Lithium counteracts depressive behavior and augments the treatment effect of selective serotonin reuptake inhibitor in treatment-resistant depressed rats.
    Brain research, 2019, 08-15, Volume: 1717

    Topics: Animals; Antidepressive Agents; Depression; Depressive Disorder, Treatment-Resistant; Disease Models, Animal; Fluoxetine; Hippocampus; Lithium; Male; Neurogenesis; Rats; Rats, Inbred WKY; Selective Serotonin Reuptake Inhibitors; Serotonin

2019
Combinational therapy of lithium and human neural stem cells in rat spinal cord contusion model.
    Journal of cellular physiology, 2019, Volume: 234, Issue:11

    Topics: Animals; Behavior, Animal; Cell Differentiation; Cell Movement; Cell Survival; Combined Modality Therapy; Disease Models, Animal; Evoked Potentials, Motor; Humans; Lithium; Macrophages; Male; Motor Activity; Neural Stem Cells; Rats, Wistar; Spinal Cord Injuries; Stem Cell Transplantation; Wound Healing

2019
Neuroprotective effects of lithium on a chronic MPTP mouse model of Parkinson's disease via regulation of α‑synuclein methylation.
    Molecular medicine reports, 2019, Volume: 19, Issue:6

    Topics: alpha-Synuclein; Animals; Behavior, Animal; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferase 1; Introns; Lithium; Male; Methylation; Mice; Mice, Inbred C57BL; MicroRNAs; MPTP Poisoning; Neuroprotective Agents; Substantia Nigra

2019
Hydrogen Alleviates Necroptosis and Cognitive Deficits in Lithium-Pilocarpine Model of Status Epilepticus.
    Cellular and molecular neurobiology, 2019, Volume: 39, Issue:6

    Topics: Animals; Apoptosis; CA1 Region, Hippocampal; Cognition Disorders; Disease Models, Animal; Hydrogen; Inflammation; Lithium; Male; Memory; Necrosis; Neurons; Neuroprotective Agents; Pilocarpine; Rats, Sprague-Dawley; Spatial Learning; Status Epilepticus

2019
Solid Stress in Brain Tumors.
    Trends in cancer, 2019, Volume: 5, Issue:5

    Topics: Animals; Brain; Brain Neoplasms; Disease Models, Animal; Humans; Lithium; Mice; Quality of Life

2019
GSK3β-mediated Keap1-independent regulation of Nrf2 antioxidant response: A molecular rheostat of acute kidney injury to chronic kidney disease transition.
    Redox biology, 2019, Volume: 26

    Topics: Acute Kidney Injury; Animals; Antioxidants; Biomarkers; Biopsy; Disease Models, Animal; Disease Progression; Disease Susceptibility; Folic Acid; Glycogen Synthase Kinase 3 beta; Immunohistochemistry; Kelch-Like ECH-Associated Protein 1; Lithium; Male; Mice; NF-E2-Related Factor 2; Renal Insufficiency, Chronic

2019
Effects of lithium and carbamazepine on spatial learning and depressive behavior in a rat model of bipolar disorder induced by ouabain.
    Pharmacology, biochemistry, and behavior, 2013, Volume: 105

    Topics: Animals; Bipolar Disorder; Carbamazepine; Depression; Disease Models, Animal; Learning; Lithium; Male; Ouabain; Rats; Rats, Wistar

2013
A comprehensive behavioral evaluation in the lithium-pilocarpine model in rats: effects of carisbamate administration during status epilepticus.
    Epilepsia, 2013, Volume: 54, Issue:7

    Topics: Animals; Anticonvulsants; Antipsychotic Agents; Behavior, Animal; Brain; Carbamates; Cell Count; Disease Models, Animal; Lithium; Male; Maze Learning; Memory; Mossy Fibers, Hippocampal; Muscarinic Agonists; Neurons; Phosphopyruvate Hydratase; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus; Visual Perception

2013
Altered hippocampal myelinated fiber integrity in a lithium-pilocarpine model of temporal lobe epilepsy: a histopathological and stereological investigation.
    Brain research, 2013, Jul-19, Volume: 1522

    Topics: Animals; Blotting, Western; Convulsants; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; Hippocampus; Immunohistochemistry; Lithium; Male; Microscopy, Electron, Transmission; Nerve Fibers, Myelinated; Pilocarpine; Rats; Rats, Sprague-Dawley

2013
Posttrauma cotreatment with lithium and valproate: reduction of lesion volume, attenuation of blood-brain barrier disruption, and improvement in motor coordination in mice with traumatic brain injury.
    Journal of neurosurgery, 2013, Volume: 119, Issue:3

    Topics: Animals; Antimanic Agents; Blood-Brain Barrier; Brain Injuries; Disease Models, Animal; Drug Therapy, Combination; Lithium; Male; Mice; Mice, Inbred C57BL; Movement Disorders; Valproic Acid

2013
Neuronal degeneration is observed in multiple regions outside the hippocampus after lithium pilocarpine-induced status epilepticus in the immature rat.
    Neuroscience, 2013, Nov-12, Volume: 252

    Topics: Animals; Brain; Convulsants; Disease Models, Animal; Hippocampus; Lithium; Nerve Degeneration; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus

2013
Pharmacometabolomic signature of ataxia SCA1 mouse model and lithium effects.
    PloS one, 2013, Volume: 8, Issue:8

    Topics: Animals; Antigens, Ly; Antipsychotic Agents; Biomarkers; Cerebellum; Disease Models, Animal; Female; Gas Chromatography-Mass Spectrometry; Lithium; Male; Membrane Proteins; Metabolome; Metabolomics; Mice; Mice, Inbred C57BL; Mice, Knockout

2013
Pharmacological blockade of IL-1β/IL-1 receptor type 1 axis during epileptogenesis provides neuroprotection in two rat models of temporal lobe epilepsy.
    Neurobiology of disease, 2013, Volume: 59

    Topics: Animals; Cell Death; Cerebral Cortex; Dipeptides; Disease Models, Animal; Electric Stimulation; Epilepsy, Temporal Lobe; Female; Glial Fibrillary Acidic Protein; Hippocampus; Humans; Interleukin 1 Receptor Antagonist Protein; Interleukin-1beta; Lithium; Male; para-Aminobenzoates; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, Interleukin-1 Type I

2013
Lithium treatment alleviates impaired cognition in a mouse model of fragile X syndrome.
    Genes, brain, and behavior, 2013, Volume: 12, Issue:7

    Topics: Age Factors; Animals; Cognition; Disease Models, Animal; Fragile X Mental Retardation Protein; Fragile X Syndrome; Lithium; Male; Mice; Mice, Inbred C57BL; Mice, Knockout

2013
Fenproporex increases locomotor activity and alters energy metabolism, and mood stabilizers reverse these changes: a proposal for a new animal model of mania.
    Molecular neurobiology, 2014, Volume: 49, Issue:2

    Topics: Amphetamines; Animals; Antimanic Agents; Bipolar Disorder; Disease Models, Animal; Dose-Response Relationship, Drug; Energy Metabolism; Lithium; Male; Motor Activity; Rats; Rats, Wistar; Valproic Acid

2014
SHANK3 overexpression causes manic-like behaviour with unique pharmacogenetic properties.
    Nature, 2013, Nov-07, Volume: 503, Issue:7474

    Topics: Actin-Related Protein 2-3 Complex; Actins; Adult; Animals; Behavior, Animal; Bipolar Disorder; Chromosomes, Human, Pair 22; Disease Models, Animal; Excitatory Postsynaptic Potentials; Female; Gene Dosage; Gene Expression; Genes, Duplicate; Humans; Hyperkinesis; Inhibitory Postsynaptic Potentials; Lithium; Male; Mice; Mice, Transgenic; Microfilament Proteins; Nerve Tissue Proteins; Seizures; Valproic Acid

2013
Effect of lithium-pilocarpine-induced status epilepticus on ultrasonic vocalizations in the infant rat pup.
    Epilepsy & behavior : E&B, 2014, Volume: 31

    Topics: Age Factors; Animals; Animals, Newborn; Chi-Square Distribution; Convulsants; Disease Models, Animal; Female; Lithium; Male; Maternal Deprivation; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus; Vocalization, Animal

2014
Dexamethasone exacerbates cerebral edema and brain injury following lithium-pilocarpine induced status epilepticus.
    Neurobiology of disease, 2014, Volume: 63

    Topics: Animals; Anti-Inflammatory Agents; Brain Edema; Brain Injuries; Cerebral Cortex; Dexamethasone; Disease Models, Animal; Image Processing, Computer-Assisted; Linear Models; Lithium; Magnetic Resonance Imaging; Male; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus; Time Factors

2014
Delayed administration of a single dose of lithium promotes recovery from AKI.
    Journal of the American Society of Nephrology : JASN, 2014, Volume: 25, Issue:3

    Topics: Acute Kidney Injury; Animals; Antimanic Agents; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cisplatin; Disease Models, Animal; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Kidney Tubules; Lithium; Male; Mice; Regeneration; Reperfusion Injury

2014
Lithium promotes neuronal repair and ameliorates depression-like behavior following trimethyltin-induced neuronal loss in the dentate gyrus.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: Animals; Behavior, Animal; beta Catenin; Bromodeoxyuridine; Cell Survival; Dentate Gyrus; Depression; Disease Models, Animal; Hippocampus; Lithium; Male; Mice; Neurons; Neuroprotective Agents; Trimethyltin Compounds

2014
Defective craniofacial development and brain function in a mouse model for depletion of intracellular inositol synthesis.
    The Journal of biological chemistry, 2014, Apr-11, Volume: 289, Issue:15

    Topics: Amino Acid Sequence; Animals; Behavior, Animal; Bipolar Disorder; Brain; Brain Diseases; Circadian Rhythm; Disease Models, Animal; Ethylnitrosourea; Female; Gene Library; Genotype; Homozygote; Humans; Inositol; Lithium; Male; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Mutagenesis; Mutation; Mutation, Missense; Phosphoric Monoester Hydrolases; Recombinant Proteins; Sequence Homology, Amino Acid; Time Factors

2014
Melatonin protects testes against lithium-pilocarpine-induced temporal lobe epilepsy in rats: a time course study.
    Andrologia, 2015, Volume: 47, Issue:3

    Topics: Animals; Apoptosis; Disease Models, Animal; Epilepsy, Temporal Lobe; Lithium; Male; Melatonin; Pilocarpine; Rats; Rats, Wistar; Sperm Motility; Spermatozoa; Testis

2015
Effective suppression of acrylamide neurotoxicity by lithium in mouse.
    Neurochemical research, 2014, Volume: 39, Issue:11

    Topics: Acrylamide; Animals; Behavior, Animal; Disease Models, Animal; Hippocampus; Lithium; Male; Mice; Neurogenesis; Neurotoxicity Syndromes; Oxidative Stress

2014
Brain intraventricular injection of amyloid-β in zebrafish embryo impairs cognition and increases tau phosphorylation, effects reversed by lithium.
    PloS one, 2014, Volume: 9, Issue:9

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; Brain; Cognition; Cognition Disorders; Disease Models, Animal; Female; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Injections, Intraventricular; Lithium; Male; Peptide Fragments; Phosphorylation; tau Proteins; Zebrafish; Zebrafish Proteins

2014
Lithium attenuates cannabinoid-induced dependence in the animal model: involvement of phosphorylated ERK1/2 and GSK-3β signaling pathways.
    Acta medica Iranica, 2014, Volume: 52, Issue:9

    Topics: Animals; Benzoxazines; Cannabinoids; Disease Models, Animal; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Lithium; Male; Morpholines; Naphthalenes; Phosphorylation; Rats; Rats, Wistar; Signal Transduction; Up-Regulation

2014
Persistent reduction of hippocampal glutamine synthetase expression after status epilepticus in immature rats.
    The European journal of neuroscience, 2014, Volume: 40, Issue:12

    Topics: Animals; Disease Models, Animal; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Glutamate-Ammonia Ligase; Hippocampus; Immunohistochemistry; Lithium; Male; Neurons; Parvalbumins; Pilocarpine; Rats, Wistar; Seizures; Status Epilepticus; Vesicular Glutamate Transport Protein 1

2014
Ameliorating effects of proglumide on neurobehavioral and biochemical deficits in animal model of status epilepticus.
    Pakistan journal of pharmaceutical sciences, 2014, Volume: 27, Issue:6

    Topics: Animals; Cognition; Disease Models, Animal; Glutathione; Lithium; Male; Motor Activity; Oxidative Stress; Pilocarpine; Proglumide; Rats; Rats, Sprague-Dawley; Status Epilepticus

2014
Histone deacetylase inhibitors reverse manic-like behaviors and protect the rat brain from energetic metabolic alterations induced by ouabain.
    Pharmacology, biochemistry, and behavior, 2015, Volume: 128

    Topics: Animals; Antimanic Agents; Behavior, Animal; Bipolar Disorder; Brain; Butyric Acid; Citric Acid Cycle; Disease Models, Animal; Energy Metabolism; Exploratory Behavior; Histone Deacetylase Inhibitors; Lithium; Male; Motor Activity; Ouabain; Rats; Rats, Wistar; Valproic Acid

2015
Bumetanide is not capable of terminating status epilepticus but enhances phenobarbital efficacy in different rat models.
    European journal of pharmacology, 2015, Jan-05, Volume: 746

    Topics: Animals; Anticonvulsants; Basolateral Nuclear Complex; Bumetanide; Disease Models, Animal; Drug Synergism; Electric Stimulation; Kainic Acid; Lithium; Male; Phenobarbital; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus

2015
Lithium prevents parkinsonian behavioral and striatal phenotypes in an aged parkin mutant transgenic mouse model.
    Brain research, 2014, Dec-03, Volume: 1591

    Topics: Aging; Animals; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Dopamine; Lithium; Mice, Transgenic; Motor Activity; Neostriatum; Neuroprotective Agents; Parkinson Disease; Substantia Nigra

2014
Systemic administration of lithium improves distracted bone regeneration in rats.
    Calcified tissue international, 2015, Volume: 96, Issue:6

    Topics: Animals; Bone Density; Bone Regeneration; Disease Models, Animal; Lithium; Male; Osteogenesis; Osteogenesis, Distraction; Rats; Rats, Sprague-Dawley; X-Ray Microtomography

2015
Serotonin Depletion Does not Modify the Short-Term Brain Hypometabolism and Hippocampal Neurodegeneration Induced by the Lithium-Pilocarpine Model of Status Epilepticus in Rats.
    Cellular and molecular neurobiology, 2016, Volume: 36, Issue:4

    Topics: Animals; Disease Models, Animal; Fenclonine; Gliosis; Hippocampus; Lithium; Magnetic Resonance Imaging; Male; Nerve Degeneration; Pilocarpine; Positron-Emission Tomography; Rats, Sprague-Dawley; Serotonin; Status Epilepticus; Time Factors

2016
Mice lacking circadian clock components display different mood-related behaviors and do not respond uniformly to chronic lithium treatment.
    Chronobiology international, 2015, Volume: 32, Issue:8

    Topics: Animals; Behavior, Animal; Bipolar Disorder; Circadian Clocks; Circadian Rhythm; CLOCK Proteins; Depression; Disease Models, Animal; Dopamine; Lithium; Mice, Knockout; Mice, Transgenic

2015
Dock3 Participate in Epileptogenesis Through rac1 Pathway in Animal Models.
    Molecular neurobiology, 2016, Volume: 53, Issue:4

    Topics: Action Potentials; Adolescent; Adult; Animals; Blotting, Western; Disease Models, Animal; Down-Regulation; Epilepsy; Excitatory Postsynaptic Potentials; Female; Green Fluorescent Proteins; Guanine Nucleotide Exchange Factors; Guanosine Triphosphate; Humans; Immunohistochemistry; Lithium; Male; Mice, Inbred C57BL; Mossy Fibers, Hippocampal; Nerve Tissue Proteins; Neurons; Pilocarpine; rac1 GTP-Binding Protein; Rats, Sprague-Dawley; RNA, Small Interfering; Signal Transduction; Young Adult

2016
Early metabolic responses to lithium/pilocarpine-induced status epilepticus in rat brain.
    Journal of neurochemistry, 2015, Volume: 135, Issue:5

    Topics: Animals; Brain; Choline; Convulsants; Disease Models, Animal; Electrochemistry; Electron Transport Chain Complex Proteins; Glucose; Lactic Acid; Lithium; Male; Microdialysis; Oxidative Stress; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus

2015
Lithium Decreases Glial Fibrillary Acidic Protein in a Mouse Model of Alexander Disease.
    PloS one, 2015, Volume: 10, Issue:9

    Topics: Alexander Disease; alpha-Crystallin B Chain; Animals; Astrocytes; Autophagy; Brain; Disease Models, Animal; Female; Gene Knock-In Techniques; Glial Fibrillary Acidic Protein; Lithium; Male; Mice; STAT3 Transcription Factor

2015
Effects of Acute Lithium Treatment on Brain Levels of Inflammatory Mediators in Poststroke Rats.
    BioMed research international, 2015, Volume: 2015

    Topics: Animals; Brain; Cytokines; Disease Models, Animal; Inflammation Mediators; Lithium; Male; Neuroprotective Agents; Rats; Rats, Wistar; Stroke

2015
The frequency of spontaneous seizures in rats correlates with alterations in sensorimotor gating, spatial working memory, and parvalbumin expression throughout limbic regions.
    Neuroscience, 2016, Jan-15, Volume: 312

    Topics: Animals; Behavior, Animal; Disease Models, Animal; Epilepsy, Temporal Lobe; Limbic System; Lithium; Male; Memory, Short-Term; Muscarinic Agonists; Parvalbumins; Pilocarpine; Prefrontal Cortex; Rats; Rats, Wistar; Seizures; Sensory Gating; Spatial Memory

2016
Advanced Sulfur Cathode Enabled by Highly Crumpled Nitrogen-Doped Graphene Sheets for High-Energy-Density Lithium-Sulfur Batteries.
    Nano letters, 2016, Feb-10, Volume: 16, Issue:2

    Topics: Animals; Disease Models, Animal; Electric Conductivity; Electric Power Supplies; Electrodes; Graphite; Hindlimb; Humans; Ischemia; Lithium; Mice; Nitrogen; Rats; Sulfur

2016
Mitochondrial dysfunction and lipid peroxidation in rat frontal cortex by chronic NMDA administration can be partially prevented by lithium treatment.
    Journal of psychiatric research, 2016, Volume: 76

    Topics: Aldehydes; Animals; Antidepressive Agents; Dinoprost; Disease Models, Animal; Excitatory Amino Acid Agonists; Frontal Lobe; Gene Expression Regulation; Lipid Peroxidation; Lithium; Male; Mitochondrial Diseases; Multienzyme Complexes; N-Methylaspartate; Rats; Rats, Inbred F344; Statistics, Nonparametric

2016
Pluronic P85-coated poly(butylcyanoacrylate) nanoparticles overcome phenytoin resistance in P-glycoprotein overexpressing rats with lithium-pilocarpine-induced chronic temporal lobe epilepsy.
    Biomaterials, 2016, Volume: 97

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chronic Disease; Disease Models, Animal; Drug Resistance; Enbucrilate; Epilepsy, Temporal Lobe; Female; Hippocampus; Lithium; Nanoparticles; Phenytoin; Pilocarpine; Poloxalene; Rats, Sprague-Dawley; Reproducibility of Results; Seizures; Tissue Distribution

2016
Hippocampal distribution of IL-1β and IL-1RI following lithium-pilocarpine-induced status epilepticus in the developing rat.
    Anais da Academia Brasileira de Ciencias, 2016, Volume: 88 Suppl 1

    Topics: Animals; Convulsants; Disease Models, Animal; Hippocampus; Interleukin-1beta; Lithium; Pilocarpine; Rats; Receptors, Interleukin-1; RNA, Messenger; Status Epilepticus

2016
Omega-3 Fatty Acids and Mood Stabilizers Alter Behavioural and Energy Metabolism Parameters in Animals Subjected to an Animal Model of Mania Induced by Fenproporex.
    Molecular neurobiology, 2017, Volume: 54, Issue:6

    Topics: Amphetamines; Animals; Antimanic Agents; Behavior, Animal; Bipolar Disorder; Citrate (si)-Synthase; Creatine Kinase; Disease Models, Animal; Energy Metabolism; Fatty Acids, Omega-3; Gene Expression Regulation; Lithium; Male; Rats, Wistar; Succinate Dehydrogenase; Valproic Acid

2017
Lithium and valproate prevent methylphenidate-induced mania-like behaviors in the hole board test.
    Neuroscience letters, 2016, 08-26, Volume: 629

    Topics: Animals; Antimanic Agents; Behavior, Animal; Bipolar Disorder; Central Nervous System Stimulants; Disease Models, Animal; Exploratory Behavior; Lithium; Locomotion; Male; Methylphenidate; Mice; Neuropsychological Tests; Valproic Acid

2016
Antinociceptive and Anti-Inflammatory Effects of Ketamine and the Relationship to Its Antidepressant Action and GSK3 Inhibition.
    Basic & clinical pharmacology & toxicology, 2016, Volume: 119, Issue:6

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Behavior, Animal; Cyclooxygenase 2; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Glycogen Synthase Kinase 3 beta; Immunohistochemistry; Ketamine; Lithium; Male; Mice; Nitric Oxide Synthase Type II; Protein Kinase Inhibitors; Receptors, N-Methyl-D-Aspartate; Subcutaneous Tissue; Tumor Necrosis Factor-alpha

2016
Immediate and delayed treatment with gabapentin, carbamazepine and CNQX have almost similar impact on cognitive functions and behavior in the lithium-pilocarpine model in rats.
    Pharmacology, biochemistry, and behavior, 2016, Volume: 148

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amines; Animals; Behavior, Animal; Carbamazepine; Cognition; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Lithium; Male; Maze Learning; Motor Activity; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus

2016
Tau Protein Mediates APP Intracellular Domain (AICD)-Induced Alzheimer's-Like Pathological Features in Mice.
    PloS one, 2016, Volume: 11, Issue:7

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Disease Models, Animal; Female; Gene Expression; Gene Knockout Techniques; Humans; Kainic Acid; Lithium; Male; Maze Learning; Memory, Short-Term; Mice; Mice, Transgenic; Neurogenesis; Neurons; Phenotype; Phosphorylation; Protein Interaction Domains and Motifs; Receptors, N-Methyl-D-Aspartate; Seizures; tau Proteins

2016
Lithium Restores Age-related Olfactory Impairment in the Ts65Dn Mouse Model of Down Syndrome.
    CNS & neurological disorders drug targets, 2017, Volume: 16, Issue:7

    Topics: Age Factors; Animals; Cell Proliferation; Dentate Gyrus; Disease Models, Animal; Down Syndrome; Female; Lateral Ventricles; Lithium; Mice; Mutation; Neurogenesis; Olfaction Disorders; Olfactory Bulb; Smell

2017
Status epilepticus alters hippocampal long-term synaptic potentiation in a rat lithium-pilocarpine model.
    Neuroreport, 2016, Nov-09, Volume: 27, Issue:16

    Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Convulsants; Disease Models, Animal; Hippocampus; In Vitro Techniques; Lithium; Long-Term Potentiation; Patch-Clamp Techniques; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus; Time Factors

2016
Pharmacologic Activation of Wnt Signaling by Lithium Normalizes Retinal Vasculature in a Murine Model of Familial Exudative Vitreoretinopathy.
    The American journal of pathology, 2016, Volume: 186, Issue:10

    Topics: Animals; Disease Models, Animal; Eye Diseases, Hereditary; Familial Exudative Vitreoretinopathies; Female; Humans; Lithium; Low Density Lipoprotein Receptor-Related Protein-5; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Retina; Retinal Diseases; Retinal Vessels; Vascular Endothelial Growth Factor A; Wnt Signaling Pathway

2016
The effects of reduced dopamine transporter function and chronic lithium on motivation, probabilistic learning, and neurochemistry in mice: Modeling bipolar mania.
    Neuropharmacology, 2017, Volume: 113, Issue:Pt A

    Topics: Animals; Bipolar Disorder; Brain Chemistry; Conditioning, Operant; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Drug Administration Schedule; Homovanillic Acid; Lithium; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motivation; Problem Solving

2017
Lithium promotes DNA stability and survival of ischemic retinal neurocytes by upregulating DNA ligase IV.
    Cell death & disease, 2016, 11-17, Volume: 7, Issue:11

    Topics: Animals; Base Sequence; Binding Sites; Blotting, Western; Cell Survival; Cells, Cultured; Chromatin Immunoprecipitation; Culture Media, Serum-Free; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; DNA; DNA Damage; DNA End-Joining Repair; DNA Ligase ATP; Electroretinography; Gene Silencing; Ischemia; Light; Lithium; NF-E2-Related Factor 1; Promoter Regions, Genetic; Rats; Reperfusion Injury; Retinal Neurons; RNA, Small Interfering; Transcription, Genetic; Up-Regulation

2016
Long-term lithium treatment increases intracellular and extracellular brain-derived neurotrophic factor (BDNF) in cortical and hippocampal neurons at subtherapeutic concentrations.
    Bipolar disorders, 2016, Volume: 18, Issue:8

    Topics: Animals; Antimanic Agents; Bipolar Disorder; Brain-Derived Neurotrophic Factor; Cells, Cultured; Cerebral Cortex; Depressive Disorder, Major; Disease Models, Animal; Hippocampus; Lithium; Long Term Adverse Effects; Neurons; Neuroprotective Agents; Rats

2016
Intranasal Delivery of miR-146a Mimics Delayed Seizure Onset in the Lithium-Pilocarpine Mouse Model.
    Mediators of inflammation, 2017, Volume: 2017

    Topics: Administration, Intranasal; Animals; Behavior, Animal; Disease Models, Animal; Epilepsy, Temporal Lobe; Hippocampus; Inflammation; Lithium; Mice; Mice, Inbred C57BL; MicroRNAs; Pilocarpine; Seizures; Time Factors

2017
Lithium treatment decreases activities of tau kinases in a murine model of senescence.
    Journal of neuropathology and experimental neurology, 2008, Volume: 67, Issue:6

    Topics: Aging; Animals; Apoptosis; Blotting, Western; Brain; Cyclin-Dependent Kinase 5; Disease Models, Animal; Enzyme Activation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Immunohistochemistry; Lithium; Mice; Neuroprotective Agents; Phosphorylation; Reverse Transcriptase Polymerase Chain Reaction; tau Proteins

2008
Inactivation of glycogen synthase kinase 3 promotes axonal growth and recovery in the CNS.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, Sep-03, Volume: 28, Issue:36

    Topics: Aminophenols; Animals; Axons; Behavior, Animal; Cells, Cultured; Central Nervous System; Cerebellum; Chondroitin Sulfate Proteoglycans; Disease Models, Animal; Enzyme Inhibitors; Ganglia, Spinal; Glycogen Synthase Kinase 3; Lithium; Locomotion; Maleimides; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neurons; Proto-Oncogene Proteins c-akt; Rats; Recovery of Function; Serotonin; Spinal Cord Injuries; Time Factors

2008
Zinc improves antioxidative enzymes in red blood cells and hematology in lithium-treated rats.
    Nutrition research (New York, N.Y.), 2008, Volume: 28, Issue:1

    Topics: Animals; Antioxidants; Catalase; Disease Models, Animal; Erythrocytes; Female; Glutathione Transferase; Lipid Peroxidation; Lithium; Random Allocation; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Superoxide Dismutase; Transaminases; Zinc; Zinc Radioisotopes

2008
Neurobehavioral maturation of offspring from epileptic dams: study in the rat lithium-pilocarpine model.
    Experimental neurology, 2009, Volume: 219, Issue:2

    Topics: Age Factors; Animals; Animals, Newborn; Antipsychotic Agents; Behavior, Animal; Body Weight; Chi-Square Distribution; Disease Models, Animal; Epilepsy; Exploratory Behavior; Eyelids; Female; Lithium; Locomotion; Male; Maternal Exposure; Maze Learning; Muscarinic Agonists; Pilocarpine; Pregnancy; Prenatal Exposure Delayed Effects; Psychomotor Performance; Random Allocation; Rats; Rats, Sprague-Dawley; Reflex; Social Behavior

2009
Uptake and retention of 65Zn in lithium-treated rat liver: role of zinc.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2010, Volume: 42, Issue:6

    Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Biological Transport; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Female; Lithium; Liver; Microsomes, Liver; Mitochondria, Liver; Rats; Rats, Wistar; Zinc; Zinc Radioisotopes

2010
A systematic study of brainstem motor nuclei in a mouse model of ALS, the effects of lithium.
    Neurobiology of disease, 2010, Volume: 37, Issue:2

    Topics: Amyotrophic Lateral Sclerosis; Animals; Axons; Biomarkers; Brain Mapping; Brain Stem; Choline O-Acetyltransferase; Cranial Nerves; Cytoprotection; Disease Models, Animal; Drug Administration Schedule; Facial Nerve; Humans; Hypoglossal Nerve; Lithium; Male; Mice; Mice, Transgenic; Motor Neurons; Nerve Degeneration; Neuroprotective Agents; Treatment Outcome; Trigeminal Nerve; Vagus Nerve

2010
Vulnerability of postnatal hippocampal neurons to seizures varies regionally with their maturational stage.
    Neurobiology of disease, 2010, Volume: 37, Issue:2

    Topics: Aging; Animals; Animals, Newborn; Antimanic Agents; Apoptosis; Apoptosis Regulatory Proteins; Calbindins; Caspase Inhibitors; Caspases; Cell Differentiation; Convulsants; Disease Models, Animal; Doublecortin Domain Proteins; Doublecortin Protein; Enzyme Inhibitors; Epilepsy; Female; Hippocampus; Lithium; Male; Microtubule-Associated Proteins; Nerve Degeneration; Neurogenesis; Neurons; Neuropeptides; Neuroprotective Agents; Pilocarpine; Rats; Rats, Wistar; S100 Calcium Binding Protein G

2010
Remarkable increase in 14C-acetate uptake in an epilepsy model rat brain induced by lithium-pilocarpine.
    Brain research, 2010, Jan-22, Volume: 1311

    Topics: Acetates; Acute Disease; Animals; Brain; Carbon Radioisotopes; Deoxyglucose; Disease Models, Animal; Epilepsy; Glucose; Iofetamine; Lithium; Male; Neuroglia; Pilocarpine; Rats; Rats, Wistar; Seizures; Time Factors

2010
Molecular basis of self-sustaining seizures and pharmacoresistance during status epilepticus: The receptor trafficking hypothesis revisited.
    Epilepsia, 2009, Volume: 50 Suppl 12

    Topics: Animals; Anticonvulsants; Disease Models, Animal; Drug Resistance; Epilepsy; Hippocampus; Humans; Immunohistochemistry; Lithium; Models, Neurological; Pilocarpine; Rats; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Status Epilepticus; Synapses

2009
Intrarenal aminopeptidase N inhibition restores defective angiontesin II type 2-mediated natriuresis in spontaneously hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:2

    Topics: Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; CD13 Antigens; Disease Models, Animal; Female; Glomerular Filtration Rate; Hypertension; Imidazoles; Lithium; Natriuresis; Probability; Pyridines; Random Allocation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 2; Sodium; Tetrazoles

2010
Nuclear translocation of mitochondrial cytochrome c, lysosomal cathepsins B and D, and three other death-promoting proteins within the first 60 minutes of generalized seizures.
    Journal of neuroscience research, 2010, Volume: 88, Issue:8

    Topics: Analysis of Variance; Animals; Apoptosis Inducing Factor; Apoptosis Regulatory Proteins; Cathepsin D; Cytochromes c; Deoxyribonucleases; Disease Models, Animal; Electroencephalography; Epilepsy, Generalized; Epoxy Compounds; Glycoside Hydrolases; Lithium; Lysosomes; Male; Mitochondria; Neurons; Pilocarpine; Protein Transport; Rats; Rats, Wistar; Tyrosine

2010
Prevention of seizures and reorganization of hippocampal functions by transplantation of bone marrow cells in the acute phase of experimental epilepsy.
    Seizure, 2010, Volume: 19, Issue:2

    Topics: Analysis of Variance; Animals; Antigens, CD; Bone Marrow Transplantation; Cell Movement; Disease Models, Animal; Electric Stimulation; Excitatory Postsynaptic Potentials; Flow Cytometry; Glial Fibrillary Acidic Protein; Green Fluorescent Proteins; Hippocampus; In Vitro Techniques; Lithium; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Patch-Clamp Techniques; Pilocarpine; Rats; Rats, Wistar; Seizures; Status Epilepticus; Time Factors

2010
GSK3 influences social preference and anxiety-related behaviors during social interaction in a mouse model of fragile X syndrome and autism.
    PloS one, 2010, Mar-16, Volume: 5, Issue:3

    Topics: Animals; Anxiety; Autistic Disorder; Behavior, Animal; Choice Behavior; Disease Models, Animal; Fragile X Mental Retardation Protein; Fragile X Syndrome; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Lithium; Male; Mice; Mice, Knockout; Social Behavior

2010
Time-dependent changes in learning ability and induction of long-term potentiation in the lithium-pilocarpine-induced epileptic mouse model.
    Epilepsy & behavior : E&B, 2010, Volume: 17, Issue:4

    Topics: Animals; Biophysics; Conditioning, Classical; Disease Models, Animal; Electric Stimulation; Excitatory Postsynaptic Potentials; Fear; GABA Antagonists; Hippocampus; In Vitro Techniques; Learning Disabilities; Lithium; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; Patch-Clamp Techniques; Picrotoxin; Pilocarpine; Status Epilepticus; Time Factors

2010
Endogenous neurosteroid synthesis modulates seizure frequency.
    Annals of neurology, 2010, Volume: 67, Issue:5

    Topics: Animals; Disease Models, Animal; Electroencephalography; Enzyme Inhibitors; Epilepsy; Female; Finasteride; Gonadotropins; Lithium; Neurotransmitter Agents; Pilocarpus; Pregnanolone; Rats

2010
Effect of ketogenic diet on nucleotide hydrolysis and hepatic enzymes in blood serum of rats in a lithium-pilocarpine-induced status epilepticus.
    Metabolic brain disease, 2010, Volume: 25, Issue:2

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Convulsants; Diet, Ketogenic; Disease Models, Animal; Enzymes; Female; Hydrolysis; Lithium; Liver; Nucleotides; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus

2010
[Expression of IL-1 mRNA in the dentate gyrus of adult rats following lithium-pilocarione-induced seizures].
    Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2010, Volume: 26, Issue:3

    Topics: Animals; Dentate Gyrus; Disease Models, Animal; Humans; Interleukin 1 Receptor Antagonist Protein; Interleukin-1beta; Lithium; Male; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, Interleukin-1; Seizures

2010
Effects of imipramine and lithium on the suppression of cell proliferation in the dentate gyrus of the hippocampus in adrenocorticotropic hormone-treated rats.
    Acta medica Okayama, 2010, Volume: 64, Issue:4

    Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents, Tricyclic; Antimanic Agents; Cell Proliferation; Dentate Gyrus; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance; Imipramine; Lithium; Male; Rats; Rats, Wistar; Sodium Chloride

2010
Inhibition of GSK-3 ameliorates Abeta pathology in an adult-onset Drosophila model of Alzheimer's disease.
    PLoS genetics, 2010, Sep-02, Volume: 6, Issue:9

    Topics: Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; Genes, Dominant; Glycogen Synthase Kinase 3; Humans; Lithium; Mutant Proteins; Nervous System; Neurons; Peptides; Phosphorylation; Phosphoserine; tau Proteins

2010
Lithium ameliorates nucleus accumbens phase-signaling dysfunction in a genetic mouse model of mania.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, Dec-01, Volume: 30, Issue:48

    Topics: Animals; Biological Clocks; Bipolar Disorder; Circadian Rhythm; CLOCK Proteins; Disease Models, Animal; Lithium; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; Nerve Net; Nucleus Accumbens; Signal Transduction

2010
Lithium fails to protect dopaminergic neurons in the 6-OHDA model of Parkinson's disease.
    Neurochemical research, 2011, Volume: 36, Issue:3

    Topics: Animals; Antipsychotic Agents; Disease Models, Animal; Dopamine; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Lithium; Male; Neurons; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Sympatholytics

2011
Persistent impairment of mitochondrial and tissue redox status during lithium-pilocarpine-induced epileptogenesis.
    Journal of neurochemistry, 2010, Volume: 115, Issue:5

    Topics: Animals; Brain; Brain Chemistry; Disease Models, Animal; DNA, Mitochondrial; Energy Metabolism; Epilepsy, Temporal Lobe; Genomic Instability; Lithium; Male; Mitochondria; Oxidation-Reduction; Oxidative Stress; Pilocarpine; Rats; Rats, Sprague-Dawley; Time

2010
Chronic lithium administration ameliorates 2,4,6-trinitrobenzene sulfonic acid-induced colitis in rats; potential role for adenosine triphosphate sensitive potassium channels.
    Journal of gastroenterology and hepatology, 2011, Volume: 26, Issue:7

    Topics: Adenosine Triphosphate; Animals; Colitis; Disease Models, Animal; Dose-Response Relationship, Drug; Follow-Up Studies; Intestinal Mucosa; Lithium; Male; Potassium Channels; Rats; Rats, Wistar; Time Factors; Trinitrobenzenesulfonic Acid

2011
Familial or genetic primary aldosteronism and Gordon syndrome.
    Endocrinology and metabolism clinics of North America, 2011, Volume: 40, Issue:2

    Topics: Animals; Arthrogryposis; Cleft Palate; Clubfoot; Diagnosis, Differential; Disease Models, Animal; Genetic Variation; Hand Deformities, Congenital; Humans; Hyperaldosteronism; Lithium; Metabolic Clearance Rate; Sodium Chloride, Dietary

2011
Defective Wnt-dependent cerebellar midline fusion in a mouse model of Joubert syndrome.
    Nature medicine, 2011, Volume: 17, Issue:6

    Topics: Abnormalities, Multiple; Adaptor Proteins, Vesicular Transport; Animals; Antigens, Neoplasm; Cell Cycle Proteins; Cerebellar Diseases; Cerebellum; Cytoskeletal Proteins; Disease Models, Animal; Eye Abnormalities; Humans; Kidney Diseases, Cystic; Lithium; Magnetic Resonance Imaging; Mice; Mice, Mutant Strains; Nuclear Proteins; Phenotype; Proto-Oncogene Proteins; Retina; Signal Transduction; Wnt Proteins

2011
Bone marrow mononuclear cells reduce seizure frequency and improve cognitive outcome in chronic epileptic rats.
    Life sciences, 2011, Aug-15, Volume: 89, Issue:7-8

    Topics: Animals; Bone Marrow Cells; Cell Transplantation; Chronic Disease; Cognition Disorders; Diazepam; Disease Models, Animal; Epilepsy; Lithium; Male; Maze Learning; Memory Disorders; Mice; Mice, Inbred C57BL; Monocytes; Pilocarpine; Rats; Rats, Wistar; Seizures; Swimming

2011
Combined treatment with the mood stabilizers lithium and valproate produces multiple beneficial effects in transgenic mouse models of Huntington's disease.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2011, Volume: 36, Issue:12

    Topics: Affect; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Huntington Disease; Lithium; Male; Mice; Mice, Transgenic; Valproic Acid

2011
An experimental study on dynamic morphological changes and expression pattern of GFAP and synapsin i in the hippocampus of MTLE models for immature rats.
    The International journal of neuroscience, 2011, Volume: 121, Issue:10

    Topics: Animals; Animals, Newborn; Cell Death; Disease Models, Animal; Epilepsy, Temporal Lobe; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Hippocampus; Lithium; Neurons; Pilocarpine; Rats; Rats, Sprague-Dawley; Synapsins; Time Factors

2011
Up-regulation of apelin in brain tissue of patients with epilepsy and an epileptic rat model.
    Peptides, 2011, Volume: 32, Issue:9

    Topics: Adolescent; Adult; Animals; Apelin; Blotting, Western; Brain; Case-Control Studies; Child; Disease Models, Animal; Epilepsy, Temporal Lobe; Female; Humans; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Lithium; Male; Neuroglia; Neurons; Pilocarpine; Rats; Rats, Sprague-Dawley; Up-Regulation; Young Adult

2011
Lithium, phenserine, memantine and pioglitazone reverse memory deficit and restore phospho-GSK3β decreased in hippocampus in intracerebroventricular streptozotocin induced memory deficit model.
    Brain research, 2011, Dec-02, Volume: 1426

    Topics: Animals; Conditioning, Classical; Disease Models, Animal; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Hippocampus; Hypoglycemic Agents; Infusions, Intraventricular; Lithium; Male; Memantine; Memory Disorders; Neuroprotective Agents; Physostigmine; Pioglitazone; Prefrontal Cortex; Rats; Rats, Wistar; Statistics, Nonparametric; Streptozocin; Thiazolidinediones

2011
Successful combined therapy with tamoxifen and lithium in a paradoxical sleep deprivation-induced mania model.
    CNS neuroscience & therapeutics, 2012, Volume: 18, Issue:2

    Topics: Animals; Antimanic Agents; Bipolar Disorder; Disease Models, Animal; Drug Therapy, Combination; Lithium; Male; Mice; Mice, Inbred C57BL; Psychomotor Agitation; Random Allocation; Sleep Deprivation; Sleep, REM; Tamoxifen

2012
Behavioral differences in black Swiss mice from separate colonies: implications for modeling domains of mania.
    Behavioural pharmacology, 2012, Volume: 23, Issue:2

    Topics: Animals; Behavior, Animal; Bipolar Disorder; Disease Models, Animal; Lithium; Male; Mice; Mice, Inbred Strains

2012
Lithium reverses increased rates of cerebral protein synthesis in a mouse model of fragile X syndrome.
    Neurobiology of disease, 2012, Volume: 45, Issue:3

    Topics: Analysis of Variance; Animals; Cerebral Cortex; Diet; Disease Models, Animal; Fragile X Mental Retardation Protein; Fragile X Syndrome; Hippocampus; Lithium; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Protein Biosynthesis; Signal Transduction; TOR Serine-Threonine Kinases

2012
Methylene blue administration fails to confer neuroprotection in two amyotrophic lateral sclerosis mouse models.
    Neuroscience, 2012, May-03, Volume: 209

    Topics: Amyotrophic Lateral Sclerosis; Animals; Antioxidants; Blotting, Western; Disease Models, Animal; DNA-Binding Proteins; Drug Therapy, Combination; Enzyme Inhibitors; Immunohistochemistry; Lithium; Methylene Blue; Mice; Mice, Inbred C57BL; Mice, Transgenic; Spinal Cord; Superoxide Dismutase; Superoxide Dismutase-1

2012
Lithium and valproate prevent olfactory discrimination and short-term memory impairments in the intranasal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) rat model of Parkinson's disease.
    Behavioural brain research, 2012, Apr-01, Volume: 229, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Administration, Intranasal; Age Factors; Animals; Animals, Newborn; Avoidance Learning; Chromatography, High Pressure Liquid; Discrimination, Psychological; Disease Models, Animal; Dopamine; Drug Administration Schedule; Drug Interactions; Exploratory Behavior; Lithium; Male; Memory Disorders; Memory, Short-Term; Neuroprotective Agents; Neurotoxins; Olfaction Disorders; Parkinsonian Disorders; Rats; Rats, Wistar; Recognition, Psychology; Serotonin; Statistics, Nonparametric; Swimming; Valproic Acid

2012
Lithium pretreatment reduces brain injury after intracerebral hemorrhage in rats.
    Neurological research, 2012, Volume: 34, Issue:5

    Topics: Animals; Brain Edema; Brain Injuries; Cell Death; Cerebral Hemorrhage; Collagen Type IV; Cyclooxygenase 2; Disease Models, Animal; Hematoma; Lithium; Male; Neuroprotective Agents; Peroxidase; Rats; Rats, Sprague-Dawley; Single-Blind Method

2012
Do proconvulsants modify or halt epileptogenesis? Pentylenetetrazole is ineffective in two rat models of temporal lobe epilepsy.
    The European journal of neuroscience, 2012, Volume: 36, Issue:4

    Topics: Animals; Convulsants; Disease Models, Animal; Epilepsy, Temporal Lobe; Female; GABA-A Receptor Agonists; Kainic Acid; Lithium; Pentylenetetrazole; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Seizures

2012
NP03, a novel low-dose lithium formulation, is neuroprotective in the YAC128 mouse model of Huntington disease.
    Neurobiology of disease, 2012, Volume: 48, Issue:3

    Topics: Animals; Brain; Disease Models, Animal; Female; Humans; Huntington Disease; Immunoblotting; Lithium; Male; Mice; Motor Activity; Neuroprotective Agents; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction

2012
Functional network changes in hippocampal CA1 after status epilepticus predict spatial memory deficits in rats.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Aug-15, Volume: 32, Issue:33

    Topics: Animals; CA1 Region, Hippocampal; Disease Models, Animal; Electrodes, Implanted; Entropy; Image Processing, Computer-Assisted; Lithium; Male; Maze Learning; Memory Disorders; Models, Neurological; Muscarinic Agonists; Nerve Net; Neurons; Pilocarpine; Predictive Value of Tests; Probability; Rats; Rats, Sprague-Dawley; Space Perception; Statistics as Topic; Statistics, Nonparametric; Status Epilepticus

2012
MicroRNA expression profile of the hippocampus in a rat model of temporal lobe epilepsy and miR-34a-targeted neuroprotection against hippocampal neurone cell apoptosis post-status epilepticus.
    BMC neuroscience, 2012, Sep-22, Volume: 13

    Topics: Analysis of Variance; Animals; Apoptosis; Caspase 3; Cell Death; Computational Biology; Disease Models, Animal; Epilepsy, Temporal Lobe; Hippocampus; In Situ Nick-End Labeling; Lithium; Male; Microarray Analysis; MicroRNAs; Neurons; Oligonucleotides; Pilocarpine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Status Epilepticus; Up-Regulation

2012
Evaluation of behavioral and neurochemical changes induced by ketamine in rats: implications as an animal model of mania.
    Journal of psychiatric research, 2012, Volume: 46, Issue:12

    Topics: Animals; Antimanic Agents; Behavior, Animal; Bipolar Disorder; Disease Models, Animal; Drug Interactions; Ketamine; Lithium; Male; Protein Carbonylation; Rats; Rats, Wistar; Valproic Acid

2012
Lithium and tamoxifen modulate cellular plasticity cascades in animal model of mania.
    Journal of psychopharmacology (Oxford, England), 2012, Volume: 26, Issue:12

    Topics: Animals; Antimanic Agents; Apoptosis; Behavior, Animal; Bipolar Disorder; Blotting, Western; Dextroamphetamine; Disease Models, Animal; Injections, Intraperitoneal; Lithium; Male; Motor Activity; Neuronal Plasticity; Protein Kinase C; Rats; Rats, Wistar; Tamoxifen

2012
Characterisation of element profile changes induced by long-term dietary supplementation of zinc in the brain and cerebellum of 3xTg-AD mice by alternated cool and normal plasma ICP-MS.
    Metallomics : integrated biometal science, 2012, Volume: 4, Issue:12

    Topics: Aluminum; Alzheimer Disease; Animals; Brain; Brain Chemistry; Cerebellum; Chromium; Cobalt; Dietary Supplements; Disease Models, Animal; Homeostasis; Lithium; Male; Mass Spectrometry; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Transgenic; Time Factors; Trace Elements; Zinc

2012
Chronic interstitial fibrosis in the rat kidney induced by long-term (6-mo) exposure to lithium.
    American journal of physiology. Renal physiology, 2013, Feb-01, Volume: 304, Issue:3

    Topics: Animals; Chronic Disease; Collagen; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrosis; Kidney; Lithium; Male; Nephritis, Interstitial; Rats; Rats, Wistar; Time Factors; Transforming Growth Factor beta1

2013
Lithium controls central nervous system autoimmunity through modulation of IFN-γ signaling.
    PloS one, 2012, Volume: 7, Issue:12

    Topics: Animals; Autoimmunity; Central Nervous System; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Glycogen Synthase Kinase 3; Interferon-gamma; Interleukins; Lithium; Male; Mice; Mice, Knockout; Multiple Sclerosis; Phosphorylation; Signal Transduction; STAT1 Transcription Factor; Th1 Cells; Th17 Cells

2012
Lithium's gene expression profile, relevance to neuroprotection A cDNA microarray study.
    Cellular and molecular neurobiology, 2013, Volume: 33, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Disease Models, Animal; Gene Expression Regulation; Lithium; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neuroprotective Agents; Oligonucleotide Array Sequence Analysis; Transcriptome

2013
Post-seizure drug treatment in young rats determines clear incremental losses of frontal cortical and hippocampal neurons: the resultant damage is similar to very old brains.
    Epilepsy & behavior : E&B, 2013, Volume: 27, Issue:1

    Topics: Age Factors; Animals; Anticonvulsants; Case-Control Studies; Cell Count; Disease Models, Animal; Drug Administration Schedule; Female; Frontal Lobe; Hippocampus; Lithium; Neurons; Pilocarpine; Rats; Seizures

2013
Status epilepticus induced by lithium-pilocarpine in the immature rat does not change the long-term susceptibility to seizures.
    Epilepsy research, 2002, Volume: 51, Issue:1-2

    Topics: Aging; Animals; Animals, Newborn; Cerebellar Cortex; Disease Models, Animal; Disease Susceptibility; Dose-Response Relationship, Drug; Electroencephalography; Excitatory Amino Acid Agonists; Female; GABA Antagonists; GABA-A Receptor Antagonists; Kainic Acid; Lithium; Male; Muscarinic Agonists; Pentylenetetrazole; Picrotoxin; Pilocarpine; Rats; Rats, Sprague-Dawley; Reaction Time; Status Epilepticus

2002
Effect of topiramate following recurrent and prolonged seizures during early development.
    Epilepsy research, 2002, Volume: 51, Issue:3

    Topics: Animals; Animals, Newborn; Anticonvulsants; Body Weight; Cell Death; Cognition; Convulsants; Disease Models, Animal; Epilepsy; Flurothyl; Fructose; Hippocampus; Lithium; Maze Learning; Mossy Fibers, Hippocampal; Muscarinic Agonists; Nerve Degeneration; Pilocarpine; Rats; Rats, Sprague-Dawley; Reaction Time; Recurrence; Research Design; Topiramate

2002
The brain matrix and multifocal brain damage following a single injection of ketamine in young adult rats: conspicuous changes in old age.
    Perceptual and motor skills, 2002, Volume: 95, Issue:3 Pt 1

    Topics: Acepromazine; Age Factors; Animals; Brain; Brain Damage, Chronic; Disease Models, Animal; Ketamine; Lithium; Male; Neurons; Pilocarpine; Rats; Rats, Wistar; Seizures

2002
Effects of cannabinoids on lithium-induced conditioned rejection reactions in a rat model of nausea.
    Psychopharmacology, 2003, Volume: 166, Issue:2

    Topics: Animals; Antiemetics; Avoidance Learning; Behavior, Animal; Cannabinoids; Conditioning, Psychological; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Lithium; Male; Nausea; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Rimonabant

2003
Neuroprotective properties of valproate: potential benefit for AD and tauopathies.
    Journal of molecular neuroscience : MN, 2002, Volume: 19, Issue:3

    Topics: Alzheimer Disease; Animals; Anticonvulsants; Clinical Trials as Topic; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Lithium; Mice; Neuroprotective Agents; Phosphorylation; Research Design; Tauopathies; Valproic Acid

2002
Effects of a glycogen synthase kinase-3 inhibitor, lithium, in adenomatous polyposis coli mutant mice.
    Pharmacological research, 2003, Volume: 48, Issue:1

    Topics: Adenomatous Polyposis Coli; Animals; Disease Models, Animal; Genes, APC; Glycogen Synthase Kinase 3; Intestinal Neoplasms; Lithium; Male; Mice; Mice, Mutant Strains; Mutation; Proto-Oncogene Proteins; Signal Transduction; Wnt Proteins; Zebrafish Proteins

2003
Development of temporal lobe epilepsy in 21-day-old rats.
    Epilepsia, 2003, Volume: 44, Issue:6

    Topics: Age Factors; Animals; Brain; Disease Models, Animal; Epilepsy, Temporal Lobe; Lithium; Magnetic Resonance Imaging; Pilocarpine; Rats; Status Epilepticus

2003
In the lithium-pilocarpine model of epilepsy, brain lesions are not linked to changes in blood-brain barrier permeability: an autoradiographic study in adult and developing rats.
    Experimental neurology, 2003, Volume: 182, Issue:2

    Topics: Age Factors; Animals; Autoradiography; Behavior, Animal; Blood Volume; Blood-Brain Barrier; Brain; Disease Models, Animal; Epilepsy; Lithium; Male; Neurons; Permeability; Pilocarpine; Rats; Rats, Sprague-Dawley

2003
Intracerebroventricular administration of ouabain as a model of mania in rats.
    Bipolar disorders, 2003, Volume: 5, Issue:5

    Topics: Animals; Bipolar Disorder; Disease Models, Animal; Drug Administration Routes; Drug Interactions; Enzyme Inhibitors; Injections, Intraventricular; Lithium; Locomotion; Male; Ouabain; Rats; Rats, Sprague-Dawley; Time Factors

2003
Pharmacological plasticity of GABA(A) receptors at dentate gyrus synapses in a rat model of temporal lobe epilepsy.
    The Journal of physiology, 2004, Jun-01, Volume: 557, Issue:Pt 2

    Topics: Animals; Anticonvulsants; Dentate Gyrus; Diazepam; Disease Models, Animal; Electric Conductivity; Epilepsy, Temporal Lobe; Flumazenil; GABA Modulators; Lithium; Male; Neural Inhibition; Patch-Clamp Techniques; Pilocarpine; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Status Epilepticus; Synapses

2004
Spontaneous recurrent seizure following status epilepticus enhances dentate gyrus neurogenesis.
    Brain & development, 2004, Volume: 26, Issue:6

    Topics: Animals; Bromodeoxyuridine; Cell Differentiation; Cell Division; Dentate Gyrus; Disease Models, Animal; Lithium; Neuronal Plasticity; Neurons; Pilocarpine; Rats; Rats, Sprague-Dawley; Recurrence; Seizures; Status Epilepticus; Stem Cells

2004
Lipopolysaccharide-induced febrile convulsions in the rat: short-term sequelae.
    Epilepsia, 2004, Volume: 45, Issue:11

    Topics: Animals; Animals, Newborn; Body Temperature; Brain; Cell Death; Disease Models, Animal; Female; Fever; Humans; Immunohistochemistry; Kainic Acid; Lipopolysaccharides; Lithium; Pentylenetetrazole; Pilocarpine; Proto-Oncogene Proteins c-fos; Random Allocation; Rats; Rats, Sprague-Dawley; Seizures, Febrile

2004
Lithium ion "cyclotron resonance" magnetic fields decrease seizure onset times in lithium-pilocarpine seized rats.
    The International journal of neuroscience, 2004, Volume: 114, Issue:8

    Topics: Analysis of Variance; Animals; Cyclotrons; Disease Models, Animal; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electromagnetic Fields; Lithium; Lithium Chloride; Magnetic Resonance Spectroscopy; Male; Pilocarpine; Rats; Rats, Wistar; Seizures; Time Factors

2004
Identification, quantification and comparison of major non-polar lipids in normal and dry eye tear lipidomes by electrospray tandem mass spectrometry.
    Journal of mass spectrometry : JMS, 2004, Volume: 39, Issue:11

    Topics: Animals; Diglycerides; Disease Models, Animal; Esters; Female; Glycerides; Keratoconjunctivitis Sicca; Lipids; Lithium; Rabbits; Spectrometry, Mass, Electrospray Ionization; Tears; Waxes

2004
N-Acetylcysteine ameliorates lithium-induced renal failure in rats.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2005, Volume: 20, Issue:1

    Topics: Acetylcysteine; Animals; Biopsy, Needle; Disease Models, Animal; Dose-Response Relationship, Drug; Glomerular Filtration Rate; Immunohistochemistry; Injections, Intraperitoneal; Kidney Function Tests; Lithium; Male; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Renal Insufficiency; Sensitivity and Specificity

2005
In vivo 1H magnetic resonance spectroscopy, T2-weighted and diffusion-weighted MRI during lithium-pilocarpine-induced status epilepticus in the rat.
    Brain research, 2004, Dec-24, Volume: 1030, Issue:1

    Topics: Animals; Brain; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Lithium; Male; Muscarinic Agonists; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus

2004
Temporal patterns of the cerebral inflammatory response in the rat lithium-pilocarpine model of temporal lobe epilepsy.
    Neurobiology of disease, 2004, Volume: 17, Issue:3

    Topics: Animals; Cyclooxygenase 2; Disease Models, Animal; Epilepsy, Temporal Lobe; Inflammation; Interleukin-1; Kinetics; Lithium; NF-kappa B; Pilocarpine; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Status Epilepticus

2004
Changes in phosphorylation of the NMDA receptor in the rat hippocampus induced by status epilepticus.
    Journal of neurochemistry, 2005, Volume: 92, Issue:6

    Topics: Animals; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Drug Synergism; Epilepsy; Focal Adhesion Kinase 2; Hippocampus; Lithium; Male; Muscarinic Agonists; Neurons; Phosphorylation; Pilocarpine; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Serine; src-Family Kinases; Status Epilepticus; Tyrosine

2005
Pharmacological rescue of synaptic plasticity, courtship behavior, and mushroom body defects in a Drosophila model of fragile X syndrome.
    Neuron, 2005, Mar-03, Volume: 45, Issue:5

    Topics: Animals; Courtship; Disease Models, Animal; Drosophila; Excitatory Amino Acid Antagonists; Female; Fragile X Syndrome; Lithium; Male; Memory; Mushroom Bodies; Neuronal Plasticity; Synapses

2005
A 5-month period of epilepsy impairs spatial memory, decreases anxiety, but spares object recognition in the lithium-pilocarpine model in adult rats.
    Epilepsia, 2005, Volume: 46, Issue:4

    Topics: Animals; Anxiety; Behavior, Animal; Cell Count; Disease Models, Animal; Entorhinal Cortex; Epilepsy, Temporal Lobe; Exploratory Behavior; Hippocampus; Lithium; Maze Learning; Memory Disorders; Neurons; Parahippocampal Gyrus; Pilocarpine; Rats; Rats, Sprague-Dawley; Seizures; Spatial Behavior

2005
Comparison of neuroprotective effects induced by alpha-phenyl-N-tert-butyl nitrone (PBN) and N-tert-butyl-alpha-(2 sulfophenyl) nitrone (S-PBN) in lithium-pilocarpine status epilepticus.
    Neurotoxicology, 2005, Volume: 26, Issue:6

    Topics: Animals; Benzenesulfonates; Brain; Cyclic N-Oxides; Disease Models, Animal; Electroencephalography; Free Radical Scavengers; Lithium; Male; Neuroprotective Agents; Nitrogen Oxides; Pilocarpine; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Status Epilepticus

2005
Sucrose ingestion decreases seizure onset time in female rats treated with lithium and pilocarpine.
    Epilepsy & behavior : E&B, 2005, Volume: 6, Issue:4

    Topics: Animals; Disease Models, Animal; Female; Lithium; Male; Muscarinic Agonists; Pilocarpine; Rats; Seizures; Sex Factors; Sucrose; Sweetening Agents; Time Factors

2005
Na+,K(+)-ATPase activity is reduced in hippocampus of rats submitted to an experimental model of depression: effect of chronic lithium treatment and possible involvement in learning deficits.
    Neurobiology of learning and memory, 2005, Volume: 84, Issue:2

    Topics: Analysis of Variance; Animals; Antidepressive Agents; Chronic Disease; Depression; Disease Models, Animal; Drug Administration Schedule; Hippocampus; Learning Disabilities; Lithium; Male; Neurons; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Stress, Psychological; Synaptic Membranes

2005
Neuroprotective mechanisms of lithium in murine human immunodeficiency virus-1 encephalitis.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Sep-14, Volume: 25, Issue:37

    Topics: Abortion, Induced; Animals; Brain; Cells, Cultured; Disease Models, Animal; Encephalitis, Viral; Fetus; HIV Infections; HIV-1; HIV-2; Humans; Lithium; Macrophages; Male; Mice; Mice, SCID; Monocytes; Neurons

2005
Chronic lithium treatment decreases tau lesions by promoting ubiquitination in a mouse model of tauopathies.
    Acta neuropathologica, 2005, Volume: 110, Issue:6

    Topics: Animals; Blotting, Western; Brain; Disease Models, Animal; Electrophoresis, Polyacrylamide Gel; Glycogen Synthase Kinase 3; Humans; Immunohistochemistry; Lithium; Mice; Mice, Transgenic; Microscopy, Confocal; Phosphorylation; tau Proteins; Tauopathies; Time Factors; Ubiquitin

2005
Lithium increases bcl-2 expression in chick cochlear nucleus and protects against deafferentation-induced cell death.
    Neuroscience, 2006, Volume: 138, Issue:4

    Topics: Afferent Pathways; Animals; Cell Count; Cell Death; Cell Size; Cell Survival; Chickens; Cochlea; Cochlear Nerve; Cochlear Nucleus; Denervation; Disease Models, Animal; Hearing Loss, Sensorineural; Lithium; Nerve Degeneration; Neuroprotective Agents; Proto-Oncogene Proteins c-bcl-2; Treatment Outcome; Up-Regulation

2006
Lithium treatment induces a marked proliferation of primarily principal cells in rat kidney inner medullary collecting duct.
    American journal of physiology. Renal physiology, 2006, Volume: 291, Issue:1

    Topics: Animals; Anion Exchange Protein 1, Erythrocyte; Apoptosis; Apoptosis Inducing Factor; Aquaporin 2; Aquaporin 4; Cell Differentiation; Cell Proliferation; Diabetes Insipidus; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Immunohistochemistry; Kidney Medulla; Kidney Tubules, Collecting; Lithium; Male; Mitosis; Polyuria; Proliferating Cell Nuclear Antigen; Proton-Translocating ATPases; Rats; Rats, Wistar; Time Factors

2006
Effects of mood stabilizers on hippocampus BDNF levels in an animal model of mania.
    Life sciences, 2006, Jun-13, Volume: 79, Issue:3

    Topics: Affect; Amphetamine; Animals; Antimanic Agents; Bipolar Disorder; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Hippocampus; Lithium; Male; Rats; Rats, Wistar; Valproic Acid

2006
Development of lithium-induced nephrogenic diabetes insipidus is dissociated from adenylyl cyclase activity.
    Journal of the American Society of Nephrology : JASN, 2006, Volume: 17, Issue:4

    Topics: Adenylyl Cyclases; Animals; Aquaporin 2; Clone Cells; Deamino Arginine Vasopressin; Diabetes Insipidus, Nephrogenic; Disease Models, Animal; Down-Regulation; In Vitro Techniques; Kidney Tubules, Collecting; Lithium; Male; Mice; Rats; Rats, Brattleboro; Rats, Wistar

2006
Lithium treatment and remodeling of the collecting duct.
    American journal of physiology. Renal physiology, 2006, Volume: 291, Issue:1

    Topics: Animals; Apoptosis; Cell Differentiation; Cell Proliferation; Diabetes Insipidus; Disease Models, Animal; Kidney Tubules, Collecting; Lithium; Male; Rats; Rats, Wistar

2006
Increase in tyrosine phosphorylation of the NMDA receptor following the induction of status epilepticus.
    Neuroscience letters, 2006, Jul-03, Volume: 401, Issue:3

    Topics: Animals; Blotting, Western; Disease Models, Animal; Enzyme Activation; Focal Adhesion Kinase 2; Guanine Nucleotide Exchange Factors; Hippocampus; Lithium; Male; Phosphorylation; Pilocarpine; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; src-Family Kinases; Status Epilepticus; Time Factors; Tyrosine

2006
Effects of uridine in models of epileptogenesis and seizures.
    Epilepsy research, 2006, Volume: 70, Issue:1

    Topics: Animals; Anticonvulsants; Behavior, Animal; Disease Models, Animal; Electroencephalography; Hippocampus; Kindling, Neurologic; Lithium; Male; Maze Learning; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus; Uridine; Water

2006
Exposure to a lithium-paired context elicits gaping in rats: A model of anticipatory nausea.
    Physiology & behavior, 2006, Jul-30, Volume: 88, Issue:4-5

    Topics: Animals; Antiemetics; Conditioning, Operant; Disease Models, Animal; Dronabinol; Infusions, Intravenous; Lithium; Male; Nausea; Ondansetron; Rats; Rats, Sprague-Dawley; Taste

2006
Lithium administration to preadolescent rats causes long-lasting increases in anxiety-like behavior and has molecular consequences.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, May-31, Volume: 26, Issue:22

    Topics: Administration, Oral; Adult; Animals; Anxiety; Bipolar Disorder; Brain; Child; Disease Models, Animal; Fear; Gene Expression Regulation; Humans; Lithium; Male; Maze Learning; Motor Activity; Oligonucleotide Array Sequence Analysis; Rats; Rats, Sprague-Dawley; Reflex, Startle; RNA

2006
Enhancement of neuroprotection and heat shock protein induction by combined prostaglandin A1 and lithium in rodent models of focal ischemia.
    Brain research, 2006, Aug-02, Volume: 1102, Issue:1

    Topics: Analysis of Variance; Animals; Blotting, Western; Brain Edema; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Heat-Shock Proteins; HSP72 Heat-Shock Proteins; Immunohistochemistry; Infarction, Middle Cerebral Artery; Lithium; Male; Molecular Chaperones; Neurologic Examination; Neuroprotective Agents; Prostaglandins A; Rats; Rats, Sprague-Dawley; Time Factors; Transcription Factor CHOP

2006
Status epilepticus differentially alters AMPA and kainate receptor subunit expression in mature and immature dentate granule neurons.
    The European journal of neuroscience, 2006, Volume: 23, Issue:11

    Topics: Animals; Animals, Newborn; Blotting, Northern; Blotting, Western; Dentate Gyrus; Disease Models, Animal; Gene Expression Regulation, Developmental; Immunohistochemistry; Lithium; Neural Cell Adhesion Molecule L1; Neurons; Phosphopyruvate Hydratase; Pilocarpine; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Reverse Transcriptase Polymerase Chain Reaction; Sialic Acids; Status Epilepticus

2006
Citicoline and lithium rescue retinal ganglion cells following partial optic nerve crush in the rat.
    Experimental eye research, 2006, Volume: 83, Issue:5

    Topics: Animals; Apoptosis; Cell Count; Cytidine Diphosphate Choline; Disease Models, Animal; Female; Immunohistochemistry; Lithium; Microscopy, Fluorescence; Neuroprotective Agents; Optic Nerve Injuries; Pharmaceutical Vehicles; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Inbred BN; Retinal Ganglion Cells

2006
The combination of topiramate and diazepam is partially neuroprotective in the hippocampus but not antiepileptogenic in the lithium-pilocarpine model of temporal lobe epilepsy.
    Epilepsy research, 2006, Volume: 72, Issue:2-3

    Topics: Animals; Anticonvulsants; Diazepam; Disease Models, Animal; Drug Therapy, Combination; Electroencephalography; Epilepsy, Temporal Lobe; Fructose; Hippocampus; Lithium; Magnetic Resonance Imaging; Male; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus; Topiramate

2006
Cch1 mediates calcium entry in Cryptococcus neoformans and is essential in low-calcium environments.
    Eukaryotic cell, 2006, Volume: 5, Issue:10

    Topics: Amino Acid Sequence; Animals; Calcium; Calcium Channels, L-Type; Cell Wall; Cryptococcosis; Cryptococcus neoformans; Disease Models, Animal; Eukaryotic Cells; Fungal Proteins; Inhalation; Lithium; Mice; Molecular Sequence Data; Mutant Proteins; Saccharomyces cerevisiae; Sequence Alignment; Temperature; Virulence

2006
Caspase-dependent programmed cell death pathways are not activated in generalized seizure-induced neuronal death.
    Brain research, 2007, Mar-02, Volume: 1135, Issue:1

    Topics: Analysis of Variance; Animals; Caspase 8; Caspase 9; Cell Count; Cell Death; Disease Models, Animal; Enzyme Activation; Immunohistochemistry; In Situ Nick-End Labeling; Lithium; Male; Neurons; Pilocarpine; Rats; Rats, Wistar; Seizures

2007
Dissociation of the immunoreactivity of synaptophysin and GAP-43 during the acute and latent phases of the lithium-pilocarpine model in the immature and adult rat.
    Experimental neurology, 2007, Volume: 204, Issue:2

    Topics: Age Factors; Animals; Animals, Newborn; Behavior, Animal; Brain; Disease Models, Animal; GAP-43 Protein; Gene Expression Regulation, Developmental; Immunohistochemistry; Lithium; Male; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus; Synaptophysin; Time Factors

2007
Beta-catenin overexpression in the mouse brain phenocopies lithium-sensitive behaviors.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2007, Volume: 32, Issue:10

    Topics: Animals; Antimanic Agents; Behavior, Animal; beta Catenin; Brain; Disease Models, Animal; Genetic Predisposition to Disease; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Lithium; Mice; Mice, Transgenic; Mood Disorders; Phenotype; Psychomotor Agitation; Up-Regulation

2007
Proteome changes associated with hippocampal MRI abnormalities in the lithium pilocarpine-induced model of convulsive status epilepticus.
    Proteomics, 2007, Volume: 7, Issue:8

    Topics: Animals; Disease Models, Animal; Electrophoresis, Gel, Two-Dimensional; Hippocampus; Humans; Lithium; Magnetic Resonance Imaging; Male; Mass Spectrometry; Muscarinic Agonists; Pilocarpine; Proteome; Rats; Rats, Sprague-Dawley; Status Epilepticus

2007
Analysis of the extracellular matrix protein SC1 during reactive gliosis in the rat lithium-pilocarpine seizure model.
    Brain research, 2007, Aug-13, Volume: 1163

    Topics: Animals; Astrocytes; Brain; Calcium-Binding Proteins; Disease Models, Animal; Extracellular Matrix Proteins; Glial Fibrillary Acidic Protein; Gliosis; Lithium; Male; Neurons; Phosphopyruvate Hydratase; Pilocarpine; Proliferating Cell Nuclear Antigen; Rats; Rats, Wistar; Seizures; Time Factors

2007
Greater stress protein expression enhanced by combined prostaglandin A1 and lithium in a rat model of focal ischemia.
    Acta pharmacologica Sinica, 2007, Volume: 28, Issue:8

    Topics: Animals; Apoptotic Protease-Activating Factor 1; Brain Ischemia; Disease Models, Animal; DNA-Binding Proteins; Heat Shock Transcription Factors; Heme Oxygenase (Decyclizing); HSP90 Heat-Shock Proteins; Lithium; Male; Prostaglandins A; Rats; Rats, Sprague-Dawley; Transcription Factors

2007
Lithium prevents stress-induced reduction of vascular endothelium growth factor levels.
    Neuroscience letters, 2007, Dec-11, Volume: 429, Issue:1

    Topics: Animals; Antimanic Agents; beta Catenin; Disease Models, Animal; Gene Expression Regulation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; Lithium; Male; Nerve Tissue Proteins; Rats; Rats, Wistar; Stress, Physiological; Vascular Endothelial Growth Factors

2007
Pentoxifylline ameliorates lithium-pilocarpine induced status epilepticus in young rats.
    Epilepsy & behavior : E&B, 2008, Volume: 12, Issue:3

    Topics: Animals; Animals, Newborn; Behavior, Animal; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Female; Functional Laterality; Glutathione; Hippocampus; Lithium; Male; Maze Learning; Motor Activity; Neurons; Pentoxifylline; Phosphodiesterase Inhibitors; Pilocarpine; Rats; Rats, Sprague-Dawley; Rotarod Performance Test; Serotonin; Status Epilepticus; Thiobarbituric Acid Reactive Substances

2008
Amiloride restores renal medullary osmolytes in lithium-induced nephrogenic diabetes insipidus.
    American journal of physiology. Renal physiology, 2008, Volume: 294, Issue:4

    Topics: Amiloride; Animals; Aquaporin 1; Diabetes Insipidus, Nephrogenic; Disease Models, Animal; Kidney Medulla; Lithium; Lithium Carbonate; Male; Potassium; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium

2008
Alterations of GABA A-receptor function and allosteric modulation during development of status epilepticus.
    Journal of neurophysiology, 2008, Volume: 99, Issue:3

    Topics: Allosteric Regulation; Animals; Anticonvulsants; Benzodiazepines; Diazepam; Disease Models, Animal; Hippocampus; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Lithium; Male; Neurons; Patch-Clamp Techniques; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, GABA; Status Epilepticus; Zinc

2008
Activation of cerebral peroxisome proliferator-activated receptors gamma exerts neuroprotection by inhibiting oxidative stress following pilocarpine-induced status epilepticus.
    Brain research, 2008, Mar-20, Volume: 1200

    Topics: Animals; Benzamides; Cell Death; Convulsants; Disease Models, Animal; Glutathione; Heme Oxygenase (Decyclizing); Hippocampus; Lipid Peroxidation; Lithium; Male; Muscarinic Agonists; Nerve Degeneration; Neuroprotective Agents; Oxidative Stress; Pilocarpine; PPAR gamma; Pyridines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Rosiglitazone; Status Epilepticus; Superoxide Dismutase; Superoxide Dismutase-1; Thiazolidinediones

2008
Programmed cell death in the lithium pilocarpine model: evidence for NMDA receptor and ceramide-mediated mechanisms.
    Brain & development, 2008, Volume: 30, Issue:8

    Topics: Animals; Cell Death; Ceramides; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Humans; In Situ Nick-End Labeling; Kainic Acid; Lithium; Male; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Seizures

2008
Zinc modulates lithium-induced hepatotoxicity in rats.
    Liver international : official journal of the International Association for the Study of the Liver, 2008, Volume: 28, Issue:4

    Topics: Analysis of Variance; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Female; Glutathione Reductase; Immunohistochemistry; Lipid Peroxidation; Lithium; Liver; Liver Diseases; Probability; Random Allocation; Rats; Rats, Wistar; Superoxide Dismutase; Zinc Sulfate

2008
[Urinary-blood delta PCO2 in renal tubular acidosis (author's transl)].
    Journal de physiologie, 1980, Volume: 76, Issue:8

    Topics: Acetazolamide; Acidosis, Renal Tubular; Amiloride; Animals; Carbon Dioxide; Chlorides; Disease Models, Animal; Lithium; Lithium Chloride; Maleates; Partial Pressure; Rats

1980
[Influence of lithium hydroxybutyrate on the electroencephalographic effects of fenamin].
    Biulleten' eksperimental'noi biologii i meditsiny, 1982, Volume: 94, Issue:7

    Topics: Amphetamine; Animals; Bipolar Disorder; Cerebral Cortex; Chlorides; Disease Models, Animal; Drug Interactions; Electroencephalography; Humans; Hydroxybutyrates; Lithium; Lithium Chloride; Organometallic Compounds; Rabbits; Schizophrenia

1982
Lithium chloride: protective and antisecretory properties in rats.
    Gastroenterology, 1984, Volume: 87, Issue:2

    Topics: Animals; Chlorides; Dinoprostone; Disease Models, Animal; Drug Evaluation; Ethanol; Gastric Acid; Gastric Mucosa; Gastritis; Gastrointestinal Hemorrhage; Indomethacin; Lithium; Lithium Chloride; Prostaglandins E; Rats; Rats, Inbred Strains

1984
A pharmacologically pertinent animal model of mania.
    Journal of affective disorders, 1981, Volume: 3, Issue:4

    Topics: Affective Disorders, Psychotic; Animals; Bipolar Disorder; Disease Models, Animal; Electroshock; Humans; Hydroxydopamines; Imipramine; Injections, Intraventricular; Lactates; Lactic Acid; Lithium; Male; Motor Activity; Oxidopamine; Rats; Rats, Inbred Strains

1981
[Comparative study of several preparations in different models of cerebral hypoxia].
    Biulleten' eksperimental'noi biologii i meditsiny, 1984, Volume: 98, Issue:11

    Topics: Animals; Asphyxia; Brain Ischemia; Disease Models, Animal; Drug Evaluation, Preclinical; Electrocardiography; Electroencephalography; Guanylthiourea; Hydroxybutyrates; Hypoxia, Brain; Lithium; Male; Organometallic Compounds; Piracetam; Rats; Sodium Nitrite; Sodium Oxybate

1984
Lithium-induced uremia in rats - a new model of chronic renal failure.
    Pflugers Archiv : European journal of physiology, 1983, Volume: 399, Issue:3

    Topics: Animals; Creatinine; Disease Models, Animal; Female; Glomerular Filtration Rate; Kidney Concentrating Ability; Kidney Failure, Chronic; Lithium; Male; Rats; Rats, Inbred Strains; Sodium; Urea; Uremia

1983
[Influence of the sex factor in weight gain caused by chronic use of lithium].
    Acta psiquiatrica y psicologica de America latina, 1983, Volume: 29, Issue:3

    Topics: Adult; Animals; Body Weight; Disease Models, Animal; Female; Humans; Hypothyroidism; Lithium; Male; Middle Aged; Rats; Rats, Inbred Strains; Sex Factors; Triiodothyronine

1983
Haloperidol-induced hyperactivity in neonatal rats: effect of lithium and stimulants.
    Pharmacology, biochemistry, and behavior, 1982, Volume: 16, Issue:1

    Topics: Animals; Animals, Newborn; Dextroamphetamine; Disease Models, Animal; Female; Haloperidol; Humans; Hyperkinesis; Lithium; Lithium Carbonate; Male; Methylphenidate; Motor Activity; Rats; Rats, Inbred Strains

1982
Cyclic Hematopoiesis: animal models.
    Experimental hematology, 1983, Volume: 11, Issue:7

    Topics: Anemia; Animals; Bone Marrow; Bone Marrow Cells; Disease Models, Animal; Dog Diseases; Dogs; Erythropoiesis; Erythropoietin; Hematopoiesis; Humans; Hypoxia; Lithium; Mice; Mice, Inbred Strains; Mink; Neutropenia; Periodicity; Prednisolone; Strontium Radioisotopes

1983
Factors affecting the sodium permeability of rat erythrocytes.
    Clinical and experimental hypertension, 1981, Volume: 3, Issue:4

    Topics: Animals; Cell Membrane Permeability; Disease Models, Animal; Erythrocytes; Female; Hypertension; Lithium; Male; Osmotic Fragility; Phloretin; Rats; Rats, Inbred Strains; Sodium; Species Specificity; Splenomegaly

1981
Red cell sodium and potassium in hemorrhagic shock measured by lithium substitution analysis.
    The Journal of trauma, 1980, Volume: 20, Issue:1

    Topics: Animals; Disease Models, Animal; Erythrocyte Membrane; Erythrocytes; Ion Channels; Lithium; Male; Potassium; Rats; Shock, Hemorrhagic; Sodium

1980
Functional mapping of the early stages of status epilepticus: a 14C-2-deoxyglucose study in the lithium-pilocarpine model in rat.
    Neuroscience, 1995, Volume: 64, Issue:4

    Topics: Animals; Autoradiography; Brain; Carbon Radioisotopes; Deoxyglucose; Disease Models, Animal; Electroencephalography; Lithium; Male; Pilocarpine; Rats; Rats, Sprague-Dawley; Seizures; Status Epilepticus

1995
Lithiuretic and natriuretic dose-response curves following constant intravenous administration of furosemide to euvolaemic rats.
    Pharmacology & toxicology, 1994, Volume: 75, Issue:6

    Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Furosemide; Glomerular Filtration Rate; Infusions, Intravenous; Lithium; Natriuresis; Rats; Rats, Wistar; Renal Circulation; Urination

1994
Effect of lithium on plasma glucose, insulin and glucagon in normal and streptozotocin-diabetic rats: role of glucagon in the hyperglycaemic response.
    British journal of pharmacology, 1994, Volume: 111, Issue:3

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucagon; Hyperglycemia; Insulin; Lithium; Male; Rats; Rats, Wistar

1994
The effect of peripheral inositol injection on rat motor activity models of depression.
    Israel journal of medical sciences, 1993, Volume: 29, Issue:9

    Topics: Amphetamine; Analysis of Variance; Animals; Apomorphine; Depression; Disease Models, Animal; Drug Synergism; Glucose; Inositol; Lithium; Male; Motor Activity; Pilocarpine; Rats; Rats, Sprague-Dawley; Seizures; Stereotyped Behavior

1993
Effects of felbamate and other anticonvulsant drugs in two models of status epilepticus in the rat.
    Research communications in chemical pathology and pharmacology, 1993, Volume: 79, Issue:3

    Topics: Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy; Felbamate; Lithium; Male; Phenylcarbamates; Pilocarpine; Propylene Glycols; Rats; Rats, Sprague-Dawley; Seizures; Status Epilepticus

1993
Chronic but not acute Li+ treatment prevents behavioral depression in rats.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1995, Volume: 28, Issue:9

    Topics: Analysis of Variance; Animals; Depression; Disease Models, Animal; Escape Reaction; Female; Lithium; Potassium; Rats; Rats, Wistar

1995
A compartmental model predicts that dietary potassium affects lithium dynamics in rats.
    The Journal of nutrition, 1996, Volume: 126, Issue:5

    Topics: Absorption; Animals; Biological Transport; Computer Simulation; Diabetes Insipidus; Diet; Disease Models, Animal; Eating; Kidney; Lithium; Male; Models, Biological; Potassium Deficiency; Potassium, Dietary; Rats; Rats, Sprague-Dawley; Time Factors

1996
Sleep deprivation in the rat: an animal model of mania.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1995, Volume: 5 Suppl

    Topics: Animals; Bipolar Disorder; Disease Models, Animal; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Ergolines; Lithium; Narcotics; Quinpirole; Rats; Sleep Deprivation

1995
Mechanism of lithium-induced polyuria in the rat.
    Kidney international, 1996, Volume: 50, Issue:2

    Topics: Animals; Arginine Vasopressin; Calcium; Diabetes Insipidus; Disease Models, Animal; Diuresis; Female; In Vitro Techniques; Kidney Medulla; Kidney Tubules, Collecting; Lithium; Male; Osmosis; Parathyroid Hormone; Parathyroidectomy; Polyuria; Punctures; Rats; Rats, Wistar; Syndrome

1996
Sodium polystyrene sulfonate treatment for lithium toxicity: effects on serum potassium concentrations.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 1996, Volume: 3, Issue:4

    Topics: Analysis of Variance; Animals; Disease Models, Animal; Drug Overdose; Hypokalemia; Lithium; Male; Mice; Mice, Inbred Strains; Polystyrenes; Potassium; Treatment Outcome

1996
Lithium distribution in experimental inflammation of brain and spinal cord.
    Progress in neuro-psychopharmacology & biological psychiatry, 1996, Volume: 20, Issue:6

    Topics: Animals; Brain; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Lithium; Rats; Rats, Inbred Lew; Spinal Cord

1996
Effects of perindopril and hydrochlorothiazide on the long-term progression of lithium-induced chronic renal failure in rats.
    Pharmacology & toxicology, 1997, Volume: 80, Issue:3

    Topics: Animals; Animals, Newborn; Antihypertensive Agents; Blood Pressure; Body Weight; Creatinine; Disease Models, Animal; Drug Interactions; Female; Glomerular Filtration Rate; Hydrochlorothiazide; Indoles; Kidney; Kidney Failure, Chronic; Kidney Function Tests; Kidney Tubules, Proximal; Lithium; Male; Perindopril; Pregnancy; Rats; Sodium; Spectrophotometry, Atomic; Urea; Uremia

1997
Acute ureteral obstruction and glomerulotubular function in rats.
    Renal failure, 1997, Volume: 19, Issue:2

    Topics: Acute Kidney Injury; Analysis of Variance; Animals; Disease Models, Animal; Glomerular Filtration Rate; Kidney Glomerulus; Kidney Tubules; Lithium; Male; Nephrectomy; Rats; Rats, Wistar; Ureteral Obstruction

1997
Emergent properties following brain injury: the claustrum as a major component of a pathway that influences nociceptive thresholds to foot shock in rats.
    Perceptual and motor skills, 1997, Volume: 85, Issue:2

    Topics: Animals; Basal Ganglia; Behavior, Animal; Brain; Brain Injuries; Disease Models, Animal; Electroshock; Foot; Lithium; Neural Pathways; Nociceptors; Pain Threshold; Pilocarpine; Rats; Seizures

1997
Modulation of lithium-pilocarpine-induced status epilepticus by adenosinergic agents.
    Methods and findings in experimental and clinical pharmacology, 1997, Volume: 19, Issue:5

    Topics: 2-Chloroadenosine; Adenosine; Animals; Anticonvulsants; Carbamazepine; Dipyridamole; Disease Models, Animal; Dose-Response Relationship, Drug; Lithium; Male; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus; Theophylline; Vasodilator Agents

1997
Dopaminergic modulation of lithium/pilocarpine-induced status epilepticus in rats.
    Methods and findings in experimental and clinical pharmacology, 1997, Volume: 19, Issue:7

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Azepines; Benzazepines; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Haloperidol; Lipid Peroxidation; Lithium; Male; Muscarinic Agonists; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus; Sulpiride

1997
The cytochrome P-450 inhibitor cobalt chloride prevents inhibition of renal Na,K-ATPase and redistribution of apical NHE-3 during acute hypertension.
    Journal of the American Society of Nephrology : JASN, 1998, Volume: 9, Issue:4

    Topics: Acute Disease; Analysis of Variance; Animals; Cobalt; Culture Techniques; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Disease Models, Animal; Hypertension; Immunoblotting; Kidney Cortex; Lithium; Male; Rats; Rats, Sprague-Dawley; Reference Values; Renal Circulation; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase; Urine

1998
The effects of lithium on a potential cycling model of bipolar disorder.
    Progress in neuro-psychopharmacology & biological psychiatry, 1998, Volume: 22, Issue:3

    Topics: Amphetamine; Animals; Antipsychotic Agents; Bipolar Disorder; Cocaine; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Drug Therapy, Combination; Lithium; Male; Models, Biological; Nucleus Accumbens; Pain; Rats; Rats, Sprague-Dawley; Stress, Psychological

1998
Esophageal electrochemical burns due to button type lithium batteries in dogs.
    Veterinary and human toxicology, 1998, Volume: 40, Issue:4

    Topics: Animals; Burns, Chemical; Burns, Electric; Disease Models, Animal; Dog Diseases; Dogs; Electric Power Supplies; Epithelium; Esophageal Diseases; Esophagus; Lithium; Mucous Membrane; Necrosis

1998
Development of self-sustaining limbic status epilepticus by continuous ventral hippocampal stimulation followed by low dose pilocarpine in rats.
    Indian journal of physiology and pharmacology, 1998, Volume: 42, Issue:3

    Topics: Animals; Anticonvulsants; Disease Models, Animal; Dizocilpine Maleate; Electroencephalography; Hippocampus; Limbic System; Lithium; Male; Neuroprotective Agents; Phenobarbital; Pilocarpine; Rats; Rats, Wistar; Seizures; Status Epilepticus; Stereotyped Behavior

1998
Progressive metabolic changes underlying the chronic reorganization of brain circuits during the silent phase of the lithium-pilocarpine model of epilepsy in the immature and adult Rat.
    Experimental neurology, 2000, Volume: 162, Issue:1

    Topics: Age Factors; Animals; Behavior, Animal; Benzoxazines; Brain Stem; Carbon Radioisotopes; Cell Death; Cerebral Cortex; Coloring Agents; Deoxyglucose; Disease Models, Animal; Epilepsy, Temporal Lobe; Female; Glucose; Lithium; Male; Muscarinic Agonists; Nerve Degeneration; Neural Pathways; Oxazines; Pilocarpine; Pregnancy; Rats; Rats, Sprague-Dawley; Silver Staining; Synapses; Time Factors

2000
Brain myo-inositol level is elevated in Ts65Dn mouse and reduced after lithium treatment.
    Neuroreport, 2000, Feb-28, Volume: 11, Issue:3

    Topics: Animals; Aspartic Acid; Brain; Choline; Creatine; Disease Models, Animal; Down Syndrome; Female; Inositol; Lithium; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Mutant Strains; Protons

2000
Long-term lithium administration abolishes the resistance to stress in rats sensitized to morphine.
    Brain research, 2000, Sep-22, Volume: 877, Issue:2

    Topics: Animals; Bipolar Disorder; Depression; Disease Models, Animal; Dopamine; Drug Administration Schedule; Drug Interactions; Escape Reaction; Lithium; Male; Morphine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Stress, Physiological

2000
The lesional and epileptogenic consequences of lithium-pilocarpine-induced status epilepticus are affected by previous exposure to isolated seizures: effects of amygdala kindling and maximal electroshocks.
    Neuroscience, 2000, Volume: 99, Issue:3

    Topics: Amygdala; Animals; Disease Models, Animal; Electroencephalography; Electroshock; Kindling, Neurologic; Lithium; Male; Muscarinic Agonists; Nerve Degeneration; Pilocarpine; Rats; Rats, Wistar; Seizures; Status Epilepticus

2000
Effects of L-arginine on prevention and treatment of lithium-pilocarpine-induced status epilepticus.
    Physiological research, 2000, Volume: 49, Issue:3

    Topics: Animals; Arginine; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy, Temporal Lobe; Lithium; Male; Muscarinic Agonists; Nitric Oxide; Pilocarpine; Rats; Rats, Wistar; Seizures; Status Epilepticus; Survival Rate

2000
Nonconvulsive status epilepticus in rats: impaired responsiveness to exteroceptive stimuli.
    Behavioural brain research, 2000, Dec-20, Volume: 117, Issue:1-2

    Topics: Animals; Behavior, Animal; Brain; Disease Models, Animal; Electroencephalography; Epilepsia Partialis Continua; Epilepsy, Complex Partial; Lithium; Male; Maze Learning; Motor Cortex; Muscarinic Agonists; Pilocarpine; Postural Balance; Random Allocation; Rats; Rats, Wistar; Social Behavior; Status Epilepticus

2000
Relationship between neuronal loss and interictal glucose metabolism during the chronic phase of the lithium-pilocarpine model of epilepsy in the immature and adult rat.
    Experimental neurology, 2001, Volume: 167, Issue:2

    Topics: Action Potentials; Age Factors; Animals; Behavior, Animal; Cell Count; Chronic Disease; Dentate Gyrus; Disease Models, Animal; Electroencephalography; Entorhinal Cortex; Epilepsy, Temporal Lobe; Glucose; Lithium; Male; Neurons; Pilocarpine; Prosencephalon; Rats; Rats, Sprague-Dawley; Seizures; Status Epilepticus; Thalamus

2001
Sodium-lithium countertransport activity is linked to chromosome 5 in baboons.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 37, Issue:2 Pt 2

    Topics: Animals; Antiporters; Disease Models, Animal; Erythrocytes; Female; Genetic Linkage; Genotype; Hypertension; Lithium; Male; Papio; Pedigree; Quantitative Trait, Heritable; Sodium

2001
Lithium suppresses excitotoxicity-induced striatal lesions in a rat model of Huntington's disease.
    Neuroscience, 2001, Volume: 106, Issue:3

    Topics: Animals; Antimanic Agents; Benzazepines; Cell Death; Cyclin D1; Disease Models, Animal; Dopamine Antagonists; Glutamate Decarboxylase; Huntington Disease; Immunohistochemistry; In Situ Nick-End Labeling; Isoenzymes; Lithium; Lithium Chloride; Male; Neostriatum; Neurons; Neuroprotective Agents; Neurotoxins; Quinolinic Acid; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; RNA, Messenger

2001
Lithium-pilocarpine-induced status epilepticus in immature rats result in long-term deficits in spatial learning and hippocampal cell loss.
    Neuroscience letters, 2001, Oct-19, Volume: 312, Issue:2

    Topics: Aging; Animals; Disease Models, Animal; Epilepsy, Temporal Lobe; Female; Hippocampus; Lithium; Male; Maze Learning; Memory Disorders; Motor Activity; Movement Disorders; Muscarinic Agonists; Nerve Degeneration; Neurons; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus

2001
Ionic mechanism of delayed afterdepolarizations in ventricular cells isolated from human end-stage failing hearts.
    Circulation, 2001, Nov-27, Volume: 104, Issue:22

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adult; Animals; Calcium; Cell Separation; Chloride Channels; Disease Models, Animal; Electric Stimulation; Female; Heart Failure; Heart Ventricles; Humans; In Vitro Techniques; Lithium; Male; Membrane Potentials; Middle Aged; Norepinephrine; Patch-Clamp Techniques; Rabbits; Sodium-Calcium Exchanger

2001
Effect of lithium and other drugs on the amphetamine chlordiazeposice hyperactivity in mice.
    Experientia, 1975, Jan-15, Volume: 31, Issue:1

    Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Bipolar Disorder; Brain Chemistry; Chlordiazepoxide; Disease Models, Animal; Dopamine beta-Hydroxylase; Enzyme Inhibitors; Female; Fenclonine; Humans; Hyperkinesis; Lithium; Mice; Motor Activity; Norepinephrine; Serotonin; Tryptophan

1975
The effects of lithium chloride on response to salient and nonsalient stimuli in Carassius auratus.
    The International journal of neuroscience, 1979, Volume: 9, Issue:3

    Topics: Animals; Bipolar Disorder; Disease Models, Animal; Exploratory Behavior; Goldfish; Humans; Lithium

1979
Selective breeding of rats for differences in reactivity to alcohol: an approach to an animal model of alcoholism. III. Some physical and behavioral measures.
    Advances in experimental medicine and biology, 1977, Volume: 85A

    Topics: Alcoholism; Animals; Body Weight; Breeding; Disease Models, Animal; Ethanol; Female; Humans; Lithium; Male; Motor Activity; Organ Size; Rats; Self Administration

1977
The effect of lithium on an animal model of tardive dyskinesia.
    Progress in neuro-psychopharmacology, 1977, Volume: 1, Issue:1-2

    Topics: Animals; Apomorphine; Dextroamphetamine; Disease Models, Animal; Dyskinesia, Drug-Induced; Guinea Pigs; Haloperidol; Humans; Lithium; Male; Receptors, Dopamine; Stereotyped Behavior

1977
Magnesium in affective disorders.
    Biological psychiatry, 1979, Volume: 14, Issue:4

    Topics: Animals; Bipolar Disorder; Calcium; Disease Models, Animal; Female; Humans; Lithium; Magnesium; Rats

1979
[Pathogenesis of stereotyped behavior].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1979, Volume: 79, Issue:9

    Topics: Animals; Behavior; Caudate Nucleus; Diazepam; Disease Models, Animal; gamma-Aminobutyric Acid; Haloperidol; Humans; Lithium; Penicillins; Picrotoxin; Rats; Schizophrenia; Stereotyped Behavior; Syndrome; Tetanus Toxin

1979
Comparative effects of dihydroergotoxine (DHET) on CBF and metabolism changes produced by experimental cerebral edema, hypoxia and hypertension.
    Gerontology, 1978, Volume: 24 Suppl 1

    Topics: Anemia; Animals; Blood Gas Analysis; Blood Glucose; Brain; Brain Edema; Cerebrovascular Circulation; Dihydroergotoxine; Disease Models, Animal; Dogs; Electroencephalography; Electrolytes; Hypertension, Renal; Hyperventilation; Hypoxia, Brain; Lactates; Lithium; Oxygen Consumption; Rabbits; Triethyltin Compounds

1978
A micropuncture study of the early phase of acute urate nephropathy.
    The Journal of clinical investigation, 1976, Volume: 58, Issue:3

    Topics: Absorption; Acute Disease; Acute Kidney Injury; Animals; Carbonates; Disease Models, Animal; Glomerular Filtration Rate; Kidney; Kidney Tubules, Distal; Kidney Tubules, Proximal; Lithium; Male; Punctures; Rats; Regional Blood Flow; Uric Acid

1976
Rat data which suggest alcoholic beverages should be swallowed during chemical aversion therapy, not just tasted.
    Behaviour research and therapy, 1976, Volume: 14, Issue:3

    Topics: Alcohol Drinking; Alcoholism; Animals; Aversive Therapy; Avoidance Learning; Disease Models, Animal; Generalization, Stimulus; Humans; Lithium; Rats; Taste

1976
[Oedema caused by polysaccharide complex (authors transl)].
    Bratislavske lekarske listy, 1975, Volume: 63, Issue:6

    Topics: Animals; Candida albicans; Carrageenan; Disease Models, Animal; Edema; Female; Lithium; Male; Phenylbutazone; Polysaccharides; Rats

1975
Reduced central serotonergic activity in mania: implications for the relationship between depression and mania.
    The British journal of psychiatry : the journal of mental science, 1975, Volume: 126

    Topics: Bipolar Disorder; Brain; Depression; Disease Models, Animal; Humans; Hydroxyindoleacetic Acid; Hypnotics and Sedatives; Imipramine; Lithium; Methysergide; Monoamine Oxidase Inhibitors; Phenylalanine; Probenecid; Serotonin; Tryptophan

1975
Seizures selectively impair agonist-stimulated phosphoinositide hydrolysis without affecting protein kinase C activity in rat brain.
    Neurotoxicology, 1992,Summer, Volume: 13, Issue:2

    Topics: Animals; Brain; Disease Models, Animal; Hippocampus; Hydrolysis; In Vitro Techniques; Lithium; Male; Norepinephrine; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Pilocarpine; Protein Kinase C; Rats; Rats, Sprague-Dawley; Status Epilepticus

1992
Light and lithium effects in the rat retina: modification by the PAF antagonist BN 52021.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 1992, Volume: 230, Issue:6

    Topics: Analysis of Variance; Animals; Disease Models, Animal; Diterpenes; Ginkgolides; Image Processing, Computer-Assisted; Lactones; Light; Lithium; Male; Phagosomes; Platelet Activating Factor; Rats; Retina; Retinal Diseases; Rod Cell Outer Segment

1992
A rodent model of focally evoked self-sustaining status epilepticus.
    European journal of pharmacology, 1992, Oct-06, Volume: 221, Issue:1

    Topics: Animals; Bicuculline; Diazepam; Disease Models, Animal; Electroencephalography; Lithium; Male; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus

1992
Multiple-dose sodium polystyrene sulfonate in lithium intoxication: an animal model.
    Pharmacology & toxicology, 1992, Volume: 70, Issue:1

    Topics: Animals; Cation Exchange Resins; Disease Models, Animal; Lithium; Male; Mice; Mice, Inbred Strains; Polystyrenes; Resins, Synthetic

1992
Porcine stress syndrome: an animal model for the neuroleptic malignant syndrome?
    Biological psychiatry, 1990, Jul-01, Volume: 28, Issue:1

    Topics: Animals; Brain; Bromocriptine; Disease Models, Animal; Haloperidol; Halothane; Hyperthermia, Induced; Lithium; Lithium Carbonate; Neuroleptic Malignant Syndrome; Pilot Projects; Receptors, Dopamine; Swine; Swine Diseases

1990
Effects of lithium on an amphetamine animal model of bipolar disorder.
    Progress in neuro-psychopharmacology & biological psychiatry, 1990, Volume: 14, Issue:3

    Topics: Animals; Bipolar Disorder; Chlorides; Dextroamphetamine; Disease Models, Animal; Lithium; Lithium Chloride; Male; Motor Activity; Rats; Rats, Inbred Strains; Reference Values; Substance Withdrawal Syndrome

1990
Effect of lithium administration on rat brain 5-hydroxyindole levels in a possible animal model for mania.
    Psychopharmacology, 1987, Volume: 91, Issue:3

    Topics: Animals; Bipolar Disorder; Brain; Chlordiazepoxide; Disease Models, Animal; Female; Hydroxyindoleacetic Acid; Lithium; Motor Activity; Rats; Rats, Inbred Strains; Serotonin

1987
The functional anatomy and pathology of lithium-pilocarpine and high-dose pilocarpine seizures.
    Neuroscience, 1987, Volume: 23, Issue:3

    Topics: Animals; Behavior, Animal; Brain; Deoxyglucose; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Injections, Subcutaneous; Lithium; Male; Pilocarpine; Rats; Rats, Inbred Strains; Seizures

1987
Inability to produce a model of dialysis encephalopathy in the rat by aluminum administration.
    Neurochemical research, 1987, Volume: 12, Issue:4

    Topics: Aluminum Hydroxide; Animals; Brain Chemistry; Brain Diseases; Choline O-Acetyltransferase; Disease Models, Animal; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Kidney Diseases; Lithium; Male; Rats; Rats, Inbred Strains; Renal Dialysis

1987
Lithium and alpha-methyl-p-tyrosine prevent "manic" activity in rodents.
    Psychopharmacologia, 1974, Apr-23, Volume: 36, Issue:3

    Topics: Animals; Bipolar Disorder; Chlordiazepoxide; Dextroamphetamine; Disease Models, Animal; Drug Combinations; Exploratory Behavior; Female; Humans; Hyperkinesis; Injections, Intraperitoneal; Lithium; Methyltyrosines; Mice; Premedication; Rats; Tyrosine 3-Monooxygenase

1974
Lithium treatment reduces morphine self-adminstration in addict rats.
    Nature, 1974, Nov-15, Volume: 252, Issue:5480

    Topics: Animals; Conditioning, Operant; Disease Models, Animal; Drinking; Drinking Behavior; Humans; Lithium; Male; Morphine; Morphine Dependence; Rats; Sucrose; Taste

1974
Exploration of the anti-depressant potential of lithium.
    Psychopharmacologia, 1973, Jan-01, Volume: 28, Issue:2

    Topics: Animals; Antidepressive Agents; Autonomic Nervous System; Behavior, Animal; Bipolar Disorder; Blood Pressure; Disease Models, Animal; Dogs; Drug Synergism; Female; Humans; Imipramine; Lithium; Male; Yohimbine

1973
[Significance of pharmaco-psychiatric findings for basic biological psychiatric research].
    Munchener medizinische Wochenschrift (1950), 1973, Apr-20, Volume: 115, Issue:16

    Topics: Antidepressive Agents; Bipolar Disorder; Catecholamines; Chlorpromazine; Deficiency Diseases; Disease Models, Animal; Humans; Imipramine; Lithium; Models, Psychological; Monoamine Oxidase Inhibitors; Psychopharmacology; Psychotic Disorders; Receptors, Drug; Structure-Activity Relationship; Tranquilizing Agents

1973
Urate excretion and urine flow in a lithium-induced diabetes insipidus rat model.
    Pflugers Archiv : European journal of physiology, 1974, Volume: 346, Issue:3

    Topics: Animals; Diabetes Insipidus; Disease Models, Animal; Injections, Intraperitoneal; Lithium; Male; Rats; Uric Acid

1974
Rubidium and lithium: opposite effects on amine-mediated excitement.
    Science (New York, N.Y.), 1971, Jun-25, Volume: 172, Issue:3990

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Disease Models, Animal; Drug Antagonism; Drug Synergism; Humans; Lithium; Male; Mice; Models, Psychological; Morphine; Motor Activity; Psychomotor Disorders; Rubidium

1971