Page last updated: 2024-08-23

lithium and Cognitive Decline

lithium has been researched along with Cognitive Decline in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's9 (45.00)24.3611
2020's11 (55.00)2.80

Authors

AuthorsStudies
Huang, Y; Li, Y; Luo, X; Ren, S; Wang, L; Wu, G; Wu, J; Wu, Q1
Li, S; Luo, X; Ma, M; Wu, Y; Xiang, T; Zeng, C1
Honyashiki, M; Inoue, T; Terao, I1
Bezerra, GAM; Corradi, MM; Damiano, RF; Di Santi, T; Forlenza, OV; Loureiro, JC; Pais, MV; Pereira, RF; Radanovic, M; Talib, LL1
Cai, Z; Chen, G; Chen, J; Li, Q; Li, R; Ma, X; Song, X; Tian, H; Xu, Y; Yang, L; Zhang, Q; Zhou, C; Zhuo, C1
Bachu, A; Madangarli, N; Patel, RS; Youssef, NA1
Chen, C; Chen, G; Cheng, L; Fang, T; Ping, J; Sun, Y; Tian, H; Wang, L; Zhu, J; Zhuo, C1
Dyomina, AV; Smolensky, IV; Zaitsev, AV1
Crocco, E; Deliyannides, DA; Devanand, DP; Forester, BP; Graff, JA; Husain, MM; Lee, S; Niño, I; Vahia, IV1
Bang, J; Jeon, WK; Kim, MS1
Ahmad, M; Taweel, GMA1
Blomgren, K; Culmsee, C; Dolga, AM; Kogner, P; Li, T; Wickström, M; Xie, C; Xu, Y; Zhang, Y; Zhou, K; Zhu, C1
Clotet, B; Díez-Quevedo, C; Ferrer, MJ; Fumaz, CR; Garolera, M; Miranda, C; Moltó, J; Muñoz-Moreno, JA; Pérez-Álvarez, N; Prats, A1
Cai, Q; Gan, J; Li, S; Luo, R; Mu, D; Qu, Y; Wan, C1
Fan, Z; Feng, X; Yin, S; Zhu, X1
Forlenza, OV; Gattaz, WF; Radanovic, M; Talib, LL1
Aprahamian, I; Diniz, BS; dos Santos, B; Forlenza, OV; Gattaz, WF; Radanovic, M; Santos, FS; Talib, L1
Lozano, R1
Aprahamian, I; Forlenza, OV1
Kalemenev, SV; Kim, KK; Lavrent'eva, VV; Lukomskaya, NY; Magazanik, LG; Sizov, VV; Zaitsev, AV; Zubareva, OE1

Reviews

1 review(s) available for lithium and Cognitive Decline

ArticleYear
Comparative efficacy of lithium and aducanumab for cognitive decline in patients with mild cognitive impairment or Alzheimer's disease: A systematic review and network meta-analysis.
    Ageing research reviews, 2022, Volume: 81

    Topics: Acetylcholinesterase; Alzheimer Disease; Antibodies, Monoclonal, Humanized; Cholinesterase Inhibitors; Cognitive Dysfunction; Humans; Lithium; Network Meta-Analysis; United States

2022

Trials

5 trial(s) available for lithium and Cognitive Decline

ArticleYear
Revisiting global cognitive and functional state 13 years after a clinical trial of lithium for mild cognitive impairment.
    Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999), 2023, Mar-11, Volume: 45, Issue:1

    Topics: Aged; Alzheimer Disease; Cognition; Cognitive Dysfunction; Cross-Sectional Studies; Humans; Lithium

2023
Effects of lithium on serum Brain-Derived Neurotrophic Factor in Alzheimer's patients with agitation.
    International journal of geriatric psychiatry, 2023, Volume: 38, Issue:9

    Topics: Alzheimer Disease; Animals; Brain-Derived Neurotrophic Factor; Cognition; Cognitive Dysfunction; Humans; Lithium

2023
Transdermal rivastigmine for HIV-associated cognitive impairment: A randomized pilot study.
    PloS one, 2017, Volume: 12, Issue:8

    Topics: Administration, Cutaneous; Adult; Anti-Retroviral Agents; Cognitive Dysfunction; Executive Function; Female; HIV Infections; Humans; Lithium; Male; Middle Aged; Neuroprotective Agents; Neuropsychological Tests; Pilot Projects; Rivastigmine; Treatment Outcome

2017
Clinical and biological effects of long-term lithium treatment in older adults with amnestic mild cognitive impairment: randomised clinical trial.
    The British journal of psychiatry : the journal of mental science, 2019, Volume: 215, Issue:5

    Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Biomarkers; Cognitive Dysfunction; Disease Progression; Humans; Lithium; Neuropsychological Tests

2019
Long-term, low-dose lithium treatment does not impair renal function in the elderly: a 2-year randomized, placebo-controlled trial followed by single-blind extension.
    The Journal of clinical psychiatry, 2014, Volume: 75, Issue:7

    Topics: Aged; Antipsychotic Agents; Cognitive Dysfunction; Double-Blind Method; Female; Humans; Kidney Diseases; Lithium; Long-Term Care; Longitudinal Studies; Male; Placebos; Single-Blind Method; Treatment Outcome

2014

Other Studies

14 other study(ies) available for lithium and Cognitive Decline

ArticleYear
Cognitive Impairment and Mossy Fiber Sprouting in a Rat Model of Drug-resistant Epilepsy Induced by Lithium-pilocarpine.
    Current neurovascular research, 2021, Volume: 18, Issue:4

    Topics: Animals; Cognitive Dysfunction; Epilepsy; Humans; Lithium; Mossy Fibers, Hippocampal; Pilocarpine; Rats

2021
Klotho ameliorated cognitive deficits in a temporal lobe epilepsy rat model by inhibiting ferroptosis.
    Brain research, 2021, 12-01, Volume: 1772

    Topics: Animals; Antioxidants; Cognitive Dysfunction; Convulsants; Epilepsy, Temporal Lobe; Ferroptosis; Genetic Therapy; Hippocampus; Iron Overload; Klotho Proteins; Lithium; Male; Neuroprotection; Pilocarpine; Rats; Rats, Sprague-Dawley

2021
Lithium produces bi-directionally regulation of mood disturbance, acts synergistically with anti-depressive/-manic agents, and did not deteriorate the cognitive impairment in murine model of bipolar disorder.
    Translational psychiatry, 2022, 09-02, Volume: 12, Issue:1

    Topics: Animals; Anticonvulsants; Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Cognitive Dysfunction; Disease Models, Animal; Lamotrigine; Lithium; Mice; Valproic Acid

2022
Electroconvulsive therapy plus lithium is associated with less cognitive impairment and drug-induced delirium in bipolar depression compared to unipolar depression.
    Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 2023, Volume: 35, Issue:2

    Topics: Adult; Bipolar Disorder; Cognitive Dysfunction; Delirium; Depressive Disorder, Major; Electroconvulsive Therapy; Humans; Lithium; Treatment Outcome

2023
Low-dose lithium adjunct to quetiapine improves cognitive task performance in mice with MK801-induced long-term cognitive impairment: Evidence from a pilot study.
    Journal of affective disorders, 2023, 11-01, Volume: 340

    Topics: Animals; Cognition; Cognitive Dysfunction; Disease Models, Animal; Dizocilpine Maleate; Humans; Lithium; Mice; Pilot Projects; Quetiapine Fumarate; Task Performance and Analysis

2023
Refinement of the Barnes and Morris water maze protocols improves characterization of spatial cognitive deficits in the lithium-pilocarpine rat model of epilepsy.
    Epilepsy & behavior : E&B, 2023, Volume: 147

    Topics: Animals; Cognition; Cognitive Dysfunction; Disease Models, Animal; Epilepsy; Epilepsy, Temporal Lobe; Lithium; Maze Learning; Morris Water Maze Test; Pilocarpine; Rats; Rats, Wistar; Spatial Learning

2023
The Involvement of Canonical Wnt Signaling in Memory Impairment Induced by Chronic Cerebral Hypoperfusion in Mice.
    Translational stroke research, 2020, Volume: 11, Issue:4

    Topics: Animals; Cerebrovascular Circulation; Cerebrovascular Disorders; Cognitive Dysfunction; Hippocampus; Lithium; Male; Memory; Memory Disorders; Mice, Inbred C57BL; Wnt Signaling Pathway

2020
Ameliorating Effects of Lithium on the Perinatal Ethanol-Induced Behavioral and Cognitive Dysfunction and Brain Oxidative Stress in Postnatal Developing Mice Pups.
    Current pharmaceutical biotechnology, 2020, Volume: 21, Issue:13

    Topics: Animals; Animals, Newborn; Behavior, Animal; Brain; Cognitive Dysfunction; Dose-Response Relationship, Drug; Ethanol; Female; Lithium; Male; Mice; Oxidative Stress; Pregnancy; Prenatal Exposure Delayed Effects; Protective Agents

2020
Lithium protects hippocampal progenitors, cognitive performance and hypothalamus-pituitary function after irradiation to the juvenile rat brain.
    Oncotarget, 2017, May-23, Volume: 8, Issue:21

    Topics: Animals; Anxiety; Cell Line, Tumor; Cell Proliferation; Cognitive Dysfunction; Cranial Irradiation; Disease Models, Animal; Hippocampus; Humans; Hyperkinesis; Lithium; Mice; Neurogenesis; Rats; Stem Cells

2017
The role of necroptosis in status epilepticus-induced brain injury in juvenile rats.
    Epilepsy & behavior : E&B, 2017, Volume: 75

    Topics: Amygdala; Animals; Biomarkers; Brain Injuries; Cognitive Dysfunction; Lithium; Male; Necrosis; Neurons; Pilocarpine; Piriform Cortex; Random Allocation; Rats; Rats, Sprague-Dawley; Status Epilepticus

2017
Immunotherapy by targeting of VGKC complex for seizure control and prevention of cognitive impairment in a mouse model of epilepsy.
    Molecular medicine reports, 2018, Volume: 18, Issue:1

    Topics: Animals; Antibodies; Cognitive Dysfunction; Disease Models, Animal; Humans; Immunotherapy; Lithium; Mice; Pilocarpine; Potassium Channels, Voltage-Gated; Seizures

2018
Renal toxicity of long-term lithium treatment for mild cognitive impairment.
    The Journal of clinical psychiatry, 2015, Volume: 76, Issue:2

    Topics: Antipsychotic Agents; Cognitive Dysfunction; Female; Humans; Kidney Diseases; Lithium; Male

2015
Drs Aprahamian and Forlenza reply.
    The Journal of clinical psychiatry, 2015, Volume: 76, Issue:2

    Topics: Antipsychotic Agents; Cognitive Dysfunction; Female; Humans; Kidney Diseases; Lithium; Male

2015
Memantine attenuates cognitive impairments after status epilepticus induced in a lithium-pilocarpine model.
    Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections, 2016, Volume: 470, Issue:1

    Topics: Animals; Cognition; Cognitive Dysfunction; Exploratory Behavior; Extinction, Psychological; Lithium; Male; Memantine; Orientation; Pilocarpine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spatial Memory; Status Epilepticus; Treatment Outcome

2016