Page last updated: 2024-08-23

lithium and Acute Confusional Senile Dementia

lithium has been researched along with Acute Confusional Senile Dementia in 80 studies

Research

Studies (80)

Timeframe	Studies, this research(%)	All Research%
pre-1990	12 (15.00)	18.7374
1990's	7 (8.75)	18.2507
2000's	20 (25.00)	29.6817
2010's	19 (23.75)	24.3611
2020's	22 (27.50)	2.80

Authors

Authors	Studies
Cardinal, RN; Chen, S; Jones, PB; Lewis, JR; Underwood, BR	1
Anchipolovsky, S; Chuang, DM; Liang, G; Vera, R; Wei, HF	1
Majidazar, R; Naseri, A; Rezazadeh-Gavgani, E; Sadigh-Eteghad, S	1
Cisternas, P; Gherardelli, C; Inestrosa, NC	1
Honyashiki, M; Inoue, T; Terao, I	1
Bezerra, GAM; Corradi, MM; Damiano, RF; Di Santi, T; Forlenza, OV; Loureiro, JC; Pais, MV; Pereira, RF; Radanovic, M; Talib, LL	1
Etoh, M; Hirakawa, H; Izumi, T; Kohno, K; Muronaga, M; Terao, T	1
Ding, X; Jiang, L; Lei, P; Li, T; Wang, W; Yang, X	1
Luca, A; Luca, M	1
Briggs, CA; Kapecki, N; Peritt, A; Peterson, DA; Shim, SS; Stutzmann, GE; Wiseman, AL	1
Fajardo, VA; Fenech, RK; Finch, MS; Hamstra, SI; MacPherson, REK; Marko, DM; Roy, BD; Ryan, CR	1
Berglund, K; Shim, SS; Yu, SP	1
Crocco, E; Deliyannides, DA; Devanand, DP; Forester, BP; Graff, JA; Husain, MM; Lee, S; Niño, I; Vahia, IV	1
Gauthier, S; Guilliot, S; Soto, ME; Touchon, J	1
Guttuso, T	1
Kanzawa, MM; Priebe, GA	1
Gruber, J; Kaur, P; Kibat, C; Lam, VYM; Lim, CH; Mathuru, AS; Teo, E; Tolwinski, NS; Zhu, F	1
Datta, LP; Govindaraju, T; Samanta, S	1
Agam, G; Damri, O; Shemesh, N	1
Barth, A; Berntsson, E; Gräslund, A; Jarvet, J; Paul, S; Roos, PM; Sholts, SB; Vosough, F; Wärmländer, S	1
Andrews, H; Crocco, E; Deliyannides, DA; Devanand, DP; Forester, BP; Huey, ED; Husain, MM; Imran, N; Lee, S; Luca, L; Pelton, GH; Simon-Pearson, L; Vahia, IV	1
Burhanullah, MH; Rosenberg, P	1
Hirakawa, H; Ishii, N; Terao, T	1
Allard, S; Cuello, AC; Do Carmo, S; Ducatenzeiler, A; Hall, H; Iulita, MF; Jia, DT; Marks, AR; Wilson, EN; Windheim, J	1
Andersen, PK; Ernstsen, V; Ersbøll, AK; Gerds, TA; Hansen, B; Jørgensen, LF; Kessing, LV; Knudsen, NN; Kristiansen, SM; Schullehner, J; Voutchkova, D	1
Fajardo, VA; LeBlanc, PJ; MacPherson, REK	1
Baranowski, BJ; Fajardo, VA; Hayward, GC; MacPherson, REK	1
Austin, GL; Butterfield, DA; Cuello, AC; Do Carmo, S; Foret, MK; Hall, H; Iulita, MF; Jia, DT; Malcolm, JC; Marks, AR; Wilson, EN	1
Horn, AHC; Huraskin, D	1
Forlenza, OV; Gattaz, WF; Radanovic, M; Talib, LL	1
Wallace, J	1
Altenhofen, S; Bonan, CD; Eltz, NS; Fonseca, R; Freitas, VM; Guerra, HN; Hackman, C; Nery, LR; Vianna, MR	1
Goossens, JL; Leverson, BD; Mota de Freitas, D	1
Appukuttan, AT; Ayton, S; Berger, G; Bush, AI; Cherny, R; Duce, JA; Finkelstein, DI; Greenough, M; Lei, P; McGorry, P; Moon, S; Pantelis, C; Volitakis, I; Wood, SJ; Yung, A	1
Dawson, HN; Fan, Q; Ghosal, K; Pimplikar, SW	1
Alberto, FL; de Sá Moreira, E; Dias-Neto, E; Forlenza, OV; Gattaz, WF; Mendes, CT; Mury, FB	1
Allen, MJ; Augustin, H; Gandy, C; Hardy, J; Kerr, F; Killick, R; Lovestone, S; Partridge, L; Rogers, I; Sofola, O	1
Cao, X; Liang, Z; Su, Y; Sun, S; Xiao, H	1
Cheng, D; Kitazawa, M; Laferla, FM; Lane, TE; Medeiros, R; Sy, M; Whitman, L	1
Colton, CA; Everhart, A; Sudduth, TL; Wilcock, DM; Wilson, JG	1
Jing, P; Ouyang, Q; Wu, J; Zhang, JY; Zhang, XJ	1
Caldaralo, V; Ciavardelli, D; Consalvo, A; Corona, C; Di Ilio, C; Di Vacri, ML; Frazzini, V; Nisi, S; Sacchetta, P; Sensi, SL; Urbani, A	1
Alvarez, G; Avila, J; Bogónez, E; Díaz-Nido, J; Muñoz-Montaño, JR; Satrústegui, J	1
Loy, R; Tariot, PN	1
Alvarez, A; Barría, MI; Bronfman, M; Chacón, MA; De Ferrari, GV; Garrido, JL; Godoy, JA; Inestrosa, NC; Olivares, G; Reyes, AE	1
De Strooper, B; Woodgett, J	1
Klein, PS; Lee, VM; Phiel, CJ; Wilson, CA	1
Pilcher, HR	1
Ghribi, O; Herman, MM; Prammonjago, P; Savory, J; Spaulding, NK	1
Avila, J; Cuadros, R; Hernández, F; Lucas, JJ	1
Li, B; Liu, F; Ni, B; Ryder, J; Su, Y; Zhou, Y	1
Abad, X; Avila, J; Bhat, R; Gómez-Ramos, A; López Fanarraga, M; Zabala, JC	1
Brune, K; Fox, N; Li, B; Liu, F; Ni, B; Paul, S; Ryder, J; Solenberg, P; Su, Y; Wu, X; Zhou, Y	1
Avila, J; Bhat, RV; Budd Haeberlein, SL	1
Bartenstein, P; Dahmen, N; Tonn, P	1
Esclaire, F; Rametti, A; Terro, F; Yardin, C	1
Inoue, Y; Iwata, N; Nakamura, J; Nakano, H; Okamoto, T; Terao, T	1
Borghgraef, P; Croes, S; Devijver, H; Dewachter, I; Jaworski, T; Kremer, A; Muyllaert, D; Van Leuven, F	1
Banay-Schwartz, M; Block, R; Gershon, S; Pomara, N; Stanley, M	1
Barnett, N; Block, R; Brinkman, SD; Domino, EF; Gershon, S; Pomara, N	1
Block, R; Domino, EF; Gershon, S; Pomara, N	1
Gershon, S; Kelwala, S; Pomara, N; Sitaram, N; Stanley, M	1
Ford, DI; Marco, LA; Mitchell, R; Plesnarski, J; Randels, PM; Scholl, M	1
Hanspal, NS; Marco, LA; Randels, PM; Robinson, B	1
Diamond, JM; Jarvik, LF; Matsuyama, SS; Meier, K	1
Bowen, DM; Clarke, NA; Francis, PT; Hodgkiss, AD; Procter, AW; Webster, MT	1
Grossberg, GT; Sky, AJ	1
Hales, RE; Kunik, ME; Silver, JM; Yudofsky, SC	1
Chen, G; Dou, L; Little, J; Manji, H; Molchan, SE; Potter, WZ; Sunderland, T	1
Ma, CM; Maesaka, JK; Piccione, JM; Wolf-Klein, G	1
Avila, J; Diaz-Nido, J; Moreno, FJ; Muñoz-Montaño, JR	1
Johnson, GV; Stoothoff, WH	1
Daya, S; Lack, B; Nyokong, T	1
Bymaster, FP; Calligaro, DO; Carter, PA; DeLapp, NW; Felder, CC	1
Schneider, LS; Sobin, PB	1
Maletta, GJ	1
Barnes, R; Risse, SC	1
Amiri, Z; Ebstein, BS; Ebstein, RP; Oppenheim, G; Stessman, J	1
Coffey, CE; Ross, DR	1
Asnes, DP	1

Reviews

17 review(s) available for lithium and Acute Confusional Senile Dementia

Article	Year
Potential mechanisms underlying lithium treatment for Alzheimer's disease and COVID-19. European review for medical and pharmacological sciences, 2022, Volume: 26, Issue:6 Topics: Alzheimer Disease; COVID-19 Drug Treatment; Humans; Lithium; Lithium Compounds; SARS-CoV-2	2022
Pharmacotherapy of Alzheimer's disease: an overview of systematic reviews. European journal of clinical pharmacology, 2022, Volume: 78, Issue:10 Topics: Alzheimer Disease; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Cholinesterase Inhibitors; Donepezil; Galantamine; Glycogen Synthase Kinase 3; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Indans; Lithium; Melatonin; Memantine; Neurodegenerative Diseases; Rivastigmine; Systematic Reviews as Topic	2022
Comparative efficacy of lithium and aducanumab for cognitive decline in patients with mild cognitive impairment or Alzheimer's disease: A systematic review and network meta-analysis. Ageing research reviews, 2022, Volume: 81 Topics: Acetylcholinesterase; Alzheimer Disease; Antibodies, Monoclonal, Humanized; Cholinesterase Inhibitors; Cognitive Dysfunction; Humans; Lithium; Network Meta-Analysis; United States	2022
Lithium: An Old Drug for New Therapeutic Strategy for Alzheimer's Disease and Related Dementia. Neuro-degenerative diseases, 2023, Volume: 23, Issue:1-2 Topics: Alzheimer Disease; Amyloid beta-Peptides; Calcium; Cognition Disorders; Humans; Lithium	2023
Lithium, a Treatment Option for Alzheimer's Disease? A Review of Existing Evidence and Discussion on Future Perspectives. Journal of Alzheimer's disease : JAD, 2023, Volume: 96, Issue:2 Topics: Alzheimer Disease; Antimanic Agents; Glycogen Synthase Kinase 3 beta; Humans; Lithium; Salts	2023
High lithium levels in tobacco may account for reduced incidences of both Parkinson's disease and melanoma in smokers through enhanced β-catenin-mediated activity. Medical hypotheses, 2019, Volume: 131 Topics: alpha-Synuclein; Alzheimer Disease; Autophagy; beta Catenin; beta-Glucosidase; Brain Chemistry; Drug Evaluation, Preclinical; Glycogen Synthase Kinase 3 beta; Humans; Incidence; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Lithium; Lithium Carbonate; Melanoma; Models, Biological; Mutation; Neuroprotective Agents; Nicotiana; Nuclear Receptor Subfamily 4, Group A, Member 2; Parkinson Disease; Parkinsonian Disorders; Smokers; Water; Wnt Signaling Pathway	2019
Is There Justification to Treat Neurodegenerative Disorders by Repurposing Drugs? The Case of Alzheimer's Disease, Lithium, and Autophagy. International journal of molecular sciences, 2020, Dec-27, Volume: 22, Issue:1 Topics: Alzheimer Disease; Animals; Apoptosis; Autophagy; Bipolar Disorder; Drug Repositioning; Glycogen Synthase Kinase 3; Homeostasis; Humans; Lithium; Neurodegenerative Diseases; Neuroprotective Agents; Oxidative Stress; Phosphoric Monoester Hydrolases	2020
The Present State of Lithium for the Prevention of Dementia Related to Alzheimer's Dementia in Clinical and Epidemiological Studies: A Critical Review. International journal of environmental research and public health, 2021, 07-22, Volume: 18, Issue:15 Topics: Alzheimer Disease; Amyloid beta-Peptides; Bipolar Disorder; Glycogen Synthase Kinase 3; Humans; Lithium	2021
A meta-analysis of mood stabilizers for Alzheimer's disease. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2010, Volume: 30, Issue:5 Topics: Aged; Alzheimer Disease; Antimanic Agents; Carbamazepine; Female; Humans; Lithium; Male; Middle Aged; Randomized Controlled Trials as Topic; Valproic Acid	2010
Regulation of tau phosphorylation and protection against beta-amyloid-induced neurodegeneration by lithium. Possible implications for Alzheimer's disease. Bipolar disorders, 2002, Volume: 4, Issue:3 Topics: Alzheimer Disease; Amyloid beta-Peptides; Apoptosis; Brain; Glycogen Synthase Kinase 3; Humans; Lithium; Nerve Degeneration; Neurofibrillary Tangles; Neurons; Phosphorylation; tau Proteins	2002
Glycogen synthase kinase 3: a drug target for CNS therapies. Journal of neurochemistry, 2004, Volume: 89, Issue:6 Topics: Alzheimer Disease; Animals; Central Nervous System Diseases; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Humans; Insulin Resistance; Lithium; Neuronal Plasticity; Neurons; Phosphorylation	2004
Glycogen synthase kinase-3beta, or a link between amyloid and tau pathology? Genes, brain, and behavior, 2008, Volume: 7 Suppl 1 Topics: Alzheimer Disease; Amyloid; Animals; Disease Models, Animal; Glycogen Synthase Kinase 3; Humans; Isoenzymes; Lithium; Mice; Mice, Transgenic; Phosphorylation; tau Proteins; Tauopathies	2008
The use of psychotropic medication in the management of problem behaviors in the patient with Alzheimer's disease. The Medical clinics of North America, 1994, Volume: 78, Issue:4 Topics: Adrenergic beta-Antagonists; Aged; Alzheimer Disease; Anticonvulsants; Benzodiazepines; Humans; Lithium; Mental Disorders; Psychotropic Drugs; Serotonin Receptor Agonists	1994
Pharmacologic approach to management of agitation associated with dementia. The Journal of clinical psychiatry, 1994, Volume: 55 Suppl Topics: Adrenergic beta-Antagonists; Aged; Aggression; Alzheimer Disease; Antipsychotic Agents; Benzodiazepines; Dementia; Drug Administration Schedule; Humans; Lithium; Psychomotor Agitation; Selective Serotonin Reuptake Inhibitors	1994
Non-neuroleptic treatment of behavioral symptoms and agitation in Alzheimer's disease and other dementia. Psychopharmacology bulletin, 1992, Volume: 28, Issue:1 Topics: Adrenergic beta-Antagonists; Alzheimer Disease; Buspirone; Carbamazepine; Dementia; Humans; Lithium; Neurotransmitter Uptake Inhibitors; Selegiline; Serotonin; Trazodone	1992
Pharmacologic treatment of agitation associated with dementia. Journal of the American Geriatrics Society, 1986, Volume: 34, Issue:5 Topics: Affective Symptoms; Aged; Aggression; Alzheimer Disease; Anti-Anxiety Agents; Antipsychotic Agents; Anxiety; Benzodiazepines; Bipolar Disorder; Carbamazepine; Dementia; Humans; Lithium; Lithium Carbonate; Propranolol; Psychotropic Drugs	1986
The cyclic AMP second messenger system in man: the effects of heredity, hormones, drugs, aluminum, age and disease on signal amplification. Progress in neuro-psychopharmacology & biological psychiatry, 1986, Volume: 10, Issue:3-5 Topics: Adenylyl Cyclases; Aging; Aluminum; Alzheimer Disease; Cyclic AMP; Female; Genetics; Homeostasis; Hormones; Humans; Lithium; Lymphocytes; Male; Receptors, Adrenergic, beta	1986

Trials

4 trial(s) available for lithium and Acute Confusional Senile Dementia

Article	Year
Revisiting global cognitive and functional state 13 years after a clinical trial of lithium for mild cognitive impairment. Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999), 2023, Mar-11, Volume: 45, Issue:1 Topics: Aged; Alzheimer Disease; Cognition; Cognitive Dysfunction; Cross-Sectional Studies; Humans; Lithium	2023
Effects of lithium on serum Brain-Derived Neurotrophic Factor in Alzheimer's patients with agitation. International journal of geriatric psychiatry, 2023, Volume: 38, Issue:9 Topics: Alzheimer Disease; Animals; Brain-Derived Neurotrophic Factor; Cognition; Cognitive Dysfunction; Humans; Lithium	2023
Low Dose Lithium Treatment of Behavioral Complications in Alzheimer's Disease: Lit-AD Randomized Clinical Trial. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2022, Volume: 30, Issue:1 Topics: Alzheimer Disease; Double-Blind Method; Humans; Lithium; Lithium Compounds; Psychomotor Agitation; Treatment Outcome	2022
Clinical and biological effects of long-term lithium treatment in older adults with amnestic mild cognitive impairment: randomised clinical trial. The British journal of psychiatry : the journal of mental science, 2019, Volume: 215, Issue:5 Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Biomarkers; Cognitive Dysfunction; Disease Progression; Humans; Lithium; Neuropsychological Tests	2019

Other Studies

59 other study(ies) available for lithium and Acute Confusional Senile Dementia

Article	Year
Association between lithium use and the incidence of dementia and its subtypes: A retrospective cohort study. PLoS medicine, 2022, Volume: 19, Issue:3 Topics: Aged; Alzheimer Disease; Cohort Studies; Dementia, Vascular; Humans; Incidence; Lithium; Male; Middle Aged	2022
Lithium Enhances Hippocampal Glucose Metabolism in an In Vitro Mice Model of Alzheimer's Disease. International journal of molecular sciences, 2022, Aug-05, Volume: 23, Issue:15 Topics: Adenosine Triphosphate; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Disease Models, Animal; Glucose; Hippocampus; Lithium; Mice; Mice, Transgenic; Presenilin-1	2022
Lithium in drinking water and Alzheimer's dementia: Epidemiological Findings from National Data Base of Japan. Bipolar disorders, 2022, Volume: 24, Issue:8 Topics: Aged; Alzheimer Disease; Bipolar Disorder; Drinking Water; Female; Humans; Japan; Lithium	2022
Head-to-Head Comparison of Different Blood Collecting Tubes for Quantification of Alzheimer's Disease Biomarkers in Plasma. Biomolecules, 2022, 08-28, Volume: 12, Issue:9 Topics: Adult; Alzheimer Disease; Amyloid beta-Peptides; Biomarkers; Edetic Acid; Female; Heparin; Humans; Lithium; Male; Peptide Fragments; tau Proteins; Young Adult	2022
Lithium in Alzheimer's disease: from prevention to treatment. Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society, 2023, Volume: 23, Issue:1 Topics: Alzheimer Disease; Humans; Lithium	2023
Lithium Provides Broad Therapeutic Benefits in an Alzheimer's Disease Mouse Model. Journal of Alzheimer's disease : JAD, 2023, Volume: 91, Issue:1 Topics: Alzheimer Disease; Animals; Calcium; Disease Models, Animal; Hippocampus; Lithium; Mice; Mice, Transgenic; Nitric Oxide Synthase Type I; tau Proteins	2023
Low-Dose Lithium Supplementation Influences GSK3β Activity in a Brain Region Specific Manner in C57BL6 Male Mice. Journal of Alzheimer's disease : JAD, 2023, Volume: 91, Issue:2 Topics: Alzheimer Disease; Animals; Brain; Dietary Supplements; Drinking Water; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Lithium; Male; Mice; Mice, Inbred C57BL; Phosphorylation	2023
Reducing the progression of Alzheimer's disease in Down syndrome patients with micro-dose lithium. Medical hypotheses, 2020, Volume: 137 Topics: Alzheimer Disease; Amyloid beta-Peptides; Down Syndrome; Glycogen Synthase Kinase 3; Humans; Lithium	2020
Application of optogenetic Amyloid-β distinguishes between metabolic and physical damages in neurodegeneration. eLife, 2020, 03-31, Volume: 9 Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Caenorhabditis elegans; Disease Progression; Drosophila; Female; HEK293 Cells; Humans; Light; Lithium; Male; Neurodegenerative Diseases; Optogenetics; Plaque, Amyloid; Zebrafish	2020
Polyampholyte-Based Synthetic Chaperone Modulate Amyloid Aggregation and Lithium Delivery. ACS chemical neuroscience, 2020, 09-16, Volume: 11, Issue:18 Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloidosis; Humans; Lithium; Plaque, Amyloid	2020
Lithium ions display weak interaction with amyloid-beta (Aβ) peptides and have minor effects on their aggregation. Acta biochimica Polonica, 2021, Apr-28, Volume: 68, Issue:2 Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Animals; Brain; Copper; Humans; Ions; Lithium; Magnetic Resonance Spectroscopy; Metals; Mice; Protein Aggregates; Protein Aggregation, Pathological	2021
Low-Dose Lithium for Management of Neuropsychiatric Symptoms in Alzheimer Disease. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2022, Volume: 30, Issue:1 Topics: Alzheimer Disease; Humans; Lithium; Neuropsychological Tests	2022
BACE1 inhibition by microdose lithium formulation NP03 rescues memory loss and early stage amyloid neuropathology. Translational psychiatry, 2017, 08-01, Volume: 7, Issue:8 Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Female; Hippocampus; Lithium; Male; Memory; Memory Disorders; Neurogenesis; Neuroprotective Agents; Rats; Rats, Transgenic	2017
Association of Lithium in Drinking Water With the Incidence of Dementia. JAMA psychiatry, 2017, 10-01, Volume: 74, Issue:10 Topics: Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Dementia; Dementia, Vascular; Denmark; Drinking Water; Environmental Exposure; Female; Humans; Incidence; Lithium; Male; Statistics as Topic; Time	2017
Examining the Relationship between Trace Lithium in Drinking Water and the Rising Rates of Age-Adjusted Alzheimer's Disease Mortality in Texas. Journal of Alzheimer's disease : JAD, 2018, Volume: 61, Issue:1 Topics: Adult; Age Factors; Alzheimer Disease; Drinking Water; Female; Humans; Lithium; Longitudinal Studies; Male; Obesity; Prevalence; Risk Factors; Statistics as Topic; Texas; Young Adult	2018
Increased Prevalence of Obesity/Type 2 Diabetes and Lower Levels of Lithium in Rural Texas Counties May Explain Greater Alzheimer's Disease Risk. Journal of Alzheimer's disease : JAD, 2018, Volume: 64, Issue:1 Topics: Alzheimer Disease; Diabetes Mellitus, Type 2; Female; Humans; Lithium; Male; Obesity; Prevalence; Retrospective Studies; Risk Factors; Rural Population; Texas; Urban Population	2018
Microdose Lithium NP03 Diminishes Pre-Plaque Oxidative Damage and Neuroinflammation in a Rat Model of Alzheimer's-like Amyloidosis. Current Alzheimer research, 2018, Volume: 15, Issue:13 Topics: Aldehydes; Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloidosis; Animals; CA1 Region, Hippocampal; Cytokines; Disease Models, Animal; Encephalitis; Humans; Lithium; Mice, Transgenic; Mutation; Plaque, Amyloid; Rats; Tyrosine	2018
Alkali ion influence on structure and stability of fibrillar amyloid-β oligomers. Journal of molecular modeling, 2019, Jan-12, Volume: 25, Issue:2 Topics: Alzheimer Disease; Amyloid beta-Peptides; Humans; Ions; Lithium; Metals, Alkali; Molecular Dynamics Simulation; Potassium; Protein Aggregates; Protein Aggregation, Pathological; Protein Conformation; Protein Multimerization; Protein Stability; Sodium	2019
Calcium dysregulation, and lithium treatment to forestall Alzheimer's disease - a merging of hypotheses. Cell calcium, 2014, Volume: 55, Issue:3 Topics: Alzheimer Disease; Calcium; Calcium Signaling; Glycogen Synthase Kinase 3; Humans; Lithium; Models, Theoretical; Neuronal Plasticity; Phosphoric Monoester Hydrolases; Receptors, N-Methyl-D-Aspartate	2014
Brain intraventricular injection of amyloid-β in zebrafish embryo impairs cognition and increases tau phosphorylation, effects reversed by lithium. PloS one, 2014, Volume: 9, Issue:9 Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; Brain; Cognition; Cognition Disorders; Disease Models, Animal; Female; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Injections, Intraventricular; Lithium; Male; Peptide Fragments; Phosphorylation; tau Proteins; Zebrafish; Zebrafish Proteins	2014
Lithium in Medicine: Mechanisms of Action. Metal ions in life sciences, 2016, Volume: 16 Topics: Alzheimer Disease; Antineoplastic Agents; Bipolar Disorder; Central Nervous System Agents; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Humans; Lithium; Magnetic Resonance Spectroscopy; Thyroid Neoplasms	2016
Lithium suppression of tau induces brain iron accumulation and neurodegeneration. Molecular psychiatry, 2017, Volume: 22, Issue:3 Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain; Humans; Iron; Lithium; Male; Mice; Mice, Knockout; Neurons; Parkinsonian Disorders; tau Proteins	2017
Tau Protein Mediates APP Intracellular Domain (AICD)-Induced Alzheimer's-Like Pathological Features in Mice. PloS one, 2016, Volume: 11, Issue:7 Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Disease Models, Animal; Female; Gene Expression; Gene Knockout Techniques; Humans; Kainic Acid; Lithium; Male; Maze Learning; Memory, Short-Term; Mice; Mice, Transgenic; Neurogenesis; Neurons; Phenotype; Phosphorylation; Protein Interaction Domains and Motifs; Receptors, N-Methyl-D-Aspartate; Seizures; tau Proteins	2016
Lithium reduces Gsk3b mRNA levels: implications for Alzheimer Disease. European archives of psychiatry and clinical neuroscience, 2009, Volume: 259, Issue:1 Topics: Alzheimer Disease; Animals; Brain; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Down-Regulation; Female; Gene Expression; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; Leukocytes; Lithium; Neurons; Polymerase Chain Reaction; Pregnancy; Rats; Rats, Wistar; RNA, Messenger	2009
Inhibition of GSK-3 ameliorates Abeta pathology in an adult-onset Drosophila model of Alzheimer's disease. PLoS genetics, 2010, Sep-02, Volume: 6, Issue:9 Topics: Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; Genes, Dominant; Glycogen Synthase Kinase 3; Humans; Lithium; Mutant Proteins; Nervous System; Neurons; Peptides; Phosphorylation; Phosphoserine; tau Proteins	2010
Inflammation induced by infection potentiates tau pathological features in transgenic mice. The American journal of pathology, 2011, Volume: 178, Issue:6 Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Animals; Cognition; Cytokines; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Inflammation; Injections; Lipopolysaccharides; Lithium; Memory; Mice; Mice, Transgenic; Murine hepatitis virus; Phosphorylation; Solubility; tau Proteins	2011
Lithium treatment of APPSwDI/NOS2-/- mice leads to reduced hyperphosphorylated tau, increased amyloid deposition and altered inflammatory phenotype. PloS one, 2012, Volume: 7, Issue:2 Topics: Alzheimer Disease; Amyloid; Amyloid beta-Protein Precursor; Animals; Humans; Inflammation; Learning; Lithium; Memory; Mice; Mice, Knockout; Mice, Transgenic; Nitric Oxide Synthase Type II; Phosphorylation; tau Proteins; Tauopathies; Treatment Outcome	2012
Lithium treatment induces proteasomal degradation of over-expressed acetylcholinesterase (AChE-S) and inhibit GSK3β. Chemico-biological interactions, 2013, Mar-25, Volume: 203, Issue:1 Topics: Acetylcholinesterase; Alzheimer Disease; Amino Acid Substitution; Animals; Enzyme Inhibitors; Enzyme Stability; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; GPI-Linked Proteins; HEK293 Cells; Humans; Leupeptins; Lithium; Mutagenesis, Site-Directed; PC12 Cells; Proteasome Endopeptidase Complex; Rats; Recombinant Proteins	2013
Characterisation of element profile changes induced by long-term dietary supplementation of zinc in the brain and cerebellum of 3xTg-AD mice by alternated cool and normal plasma ICP-MS. Metallomics : integrated biometal science, 2012, Volume: 4, Issue:12 Topics: Aluminum; Alzheimer Disease; Animals; Brain; Brain Chemistry; Cerebellum; Chromium; Cobalt; Dietary Supplements; Disease Models, Animal; Homeostasis; Lithium; Male; Mass Spectrometry; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Transgenic; Time Factors; Trace Elements; Zinc	2012
Neuroprotective properties of valproate: potential benefit for AD and tauopathies. Journal of molecular neuroscience : MN, 2002, Volume: 19, Issue:3 Topics: Alzheimer Disease; Animals; Anticonvulsants; Clinical Trials as Topic; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Lithium; Mice; Neuroprotective Agents; Phosphorylation; Research Design; Tauopathies; Valproic Acid	2002
Activation of Wnt signaling rescues neurodegeneration and behavioral impairments induced by beta-amyloid fibrils. Molecular psychiatry, 2003, Volume: 8, Issue:2 Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Behavior, Animal; beta Catenin; Cell Death; Cells, Cultured; Culture Media, Conditioned; Cytoskeletal Proteins; Humans; Isoenzymes; Kidney; Lithium; Memory Disorders; Mice; Nerve Degeneration; Neurons; Protein Kinase C; Proteins; Rats; Rats, Sprague-Dawley; Signal Transduction; Trans-Activators; Transfection; Wnt Proteins; Wnt3 Protein; Wnt3A Protein	2003
Alzheimer's disease: Mental plaque removal. Nature, 2003, May-22, Volume: 423, Issue:6938 Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Brain; Endopeptidases; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Lithium; Mice; Neurofibrillary Tangles; Peptide Fragments; Phosphorylation; Plaque, Amyloid	2003
GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides. Nature, 2003, May-22, Volume: 423, Issue:6938 Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Brain; Cells, Cultured; CHO Cells; Cricetinae; Endopeptidases; Glycogen Synthase Kinase 3; Lithium; Membrane Proteins; Mice; Neurons; Peptide Fragments; Phosphorylation; Receptors, Notch	2003
Drug research: the ups and downs of lithium. Nature, 2003, Sep-11, Volume: 425, Issue:6954 Topics: Affect; Alzheimer Disease; Animals; Bipolar Disorder; Brain; Glycogen Synthase Kinase 3; Humans; Inositol; Lithium; Male; Neurons; Second Messenger Systems; Stem Cells	2003
Abeta(1-42)-induced JNK and ERK activation in rabbit hippocampus is differentially regulated by lithium but is not involved in the phosphorylation of tau. Brain research. Molecular brain research, 2003, Nov-26, Volume: 119, Issue:2 Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; Enzyme Activation; Female; Hippocampus; JNK Mitogen-Activated Protein Kinases; Lithium; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Neurons; Peptide Fragments; Phosphorylation; Rabbits; tau Proteins	2003
GSK-3 dependent phosphoepitopes recognized by PHF-1 and AT-8 antibodies are present in different tau isoforms. Neurobiology of aging, 2003, Volume: 24, Issue:8 Topics: Alzheimer Disease; Amino Acid Sequence; Antibodies; Antibodies, Monoclonal; Brain; Brain Chemistry; Cell Compartmentation; Cell Line, Tumor; Epitopes; Glycogen Synthase Kinase 3; Humans; Lithium; Molecular Sequence Data; Neurons; Phosphorylation; Protein Isoforms; tau Proteins	2003
Divergent roles of GSK3 and CDK5 in APP processing. Biochemical and biophysical research communications, 2003, Dec-26, Volume: 312, Issue:4 Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cell Line; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Dose-Response Relationship, Drug; Glycogen Synthase Kinase 3; Lithium; Mice; Mice, Transgenic; Purines; Roscovitine	2003
Expression of an altered form of tau in Sf9 insect cells results in the assembly of polymers resembling Alzheimer's paired helical filaments. Brain research, 2004, May-08, Volume: 1007, Issue:1-2 Topics: Actin Cytoskeleton; Alzheimer Disease; Animals; Baculoviridae; Blotting, Western; Cell Line; Female; Fluorescent Antibody Technique; Gene Expression Regulation; Humans; Insecta; Lithium; Microscopy, Immunoelectron; Microtubule-Associated Proteins; Microtubules; Mutagenesis, Site-Directed; Mutation; Neurofibrillary Tangles; Ovary; Phosphorylation; tau Proteins; Transfection	2004
Lithium, a common drug for bipolar disorder treatment, regulates amyloid-beta precursor protein processing. Biochemistry, 2004, Jun-08, Volume: 43, Issue:22 Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Bipolar Disorder; Brain; Cells, Cultured; Enzyme Inhibitors; Genes, Dominant; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Lithium; Mice; Mice, Transgenic; Oligonucleotides, Antisense; Protein Processing, Post-Translational; Valproic Acid	2004
[Lithium intoxication mimics Alzheimer's disease in PET and clinical findings]. Der Nervenarzt, 2005, Volume: 76, Issue:5 Topics: Aged; Alzheimer Disease; Brain; Diagnosis, Differential; Diagnostic Errors; Female; Fluorodeoxyglucose F18; Humans; Lithium; Neuropsychological Tests; Positron-Emission Tomography; Radiopharmaceuticals	2005
Linking alterations in tau phosphorylation and cleavage during neuronal apoptosis. The Journal of biological chemistry, 2004, Dec-24, Volume: 279, Issue:52 Topics: Alzheimer Disease; Animals; Apoptosis; Caspase Inhibitors; Cells, Cultured; Cerebral Cortex; Colchicine; Embryo, Mammalian; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Lithium; Neurons; Okadaic Acid; Peptide Fragments; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 2; Rats; Rats, Wistar; Staurosporine; tau Proteins	2004
Lithium and dementia: a preliminary study. Progress in neuro-psychopharmacology & biological psychiatry, 2006, Aug-30, Volume: 30, Issue:6 Topics: Aged; Alzheimer Disease; Bipolar Disorder; Cognition; Cohort Studies; Dementia; Female; Humans; Lithium; Male; Middle Aged; Neuropsychological Tests; Psychiatric Status Rating Scales	2006
Elevation of RBC glycine and choline levels in geriatric patients treated with lithium. The American journal of psychiatry, 1983, Volume: 140, Issue:7 Topics: Aged; Alzheimer Disease; Choline; Cognition Disorders; Dementia; Erythrocytes; Female; Glycine; Humans; Lithium; Lithium Carbonate; Male	1983
Lithium-induced increases in red blood cell choline and memory performance in Alzheimer-type dementia. Biological psychiatry, 1984, Volume: 19, Issue:2 Topics: Aged; Alzheimer Disease; Choline; Erythrocytes; Humans; Lithium; Lithium Carbonate; Memory; Middle Aged	1984
Decay in plasma lithium and normalization in red blood cell choline following cessation of lithium treatment in two elderly individuals with Alzheimer-type dementia. Biological psychiatry, 1984, Volume: 19, Issue:6 Topics: Aged; Alzheimer Disease; Choline; Erythrocytes; Humans; Lithium; Lithium Carbonate; Male; Substance Withdrawal Syndrome	1984
Lithium-induced accentuation of extrapyramidal symptoms in individuals with Alzheimer's disease. The Journal of clinical psychiatry, 1984, Volume: 45, Issue:8 Topics: Acute Disease; Aged; Alzheimer Disease; Basal Ganglia Diseases; Erythrocytes; Female; Humans; Lithium; Lithium Carbonate; Male; Middle Aged	1984
Lithium and lecithin treatment in Alzheimer's disease: a pilot study. The Hillside journal of clinical psychiatry, 1984, Volume: 6, Issue:2 Topics: Aged; Alzheimer Disease; Basal Ganglia Diseases; Cognition; Drug Therapy, Combination; Humans; Lithium; Lithium Carbonate; Male; Middle Aged; Phosphatidylcholines; Pilot Projects	1984
Possible lithium-induced extrapyramidal effects in Alzheimer's disease. The Hillside journal of clinical psychiatry, 1984, Volume: 6, Issue:1 Topics: Alzheimer Disease; Basal Ganglia Diseases; Humans; Lithium; Male; Middle Aged	1984
Elevation of erythrocyte countertransport rates in Alzheimer's dementia. The New England journal of medicine, 1983, Oct-27, Volume: 309, Issue:17 Topics: Aged; Alzheimer Disease; Biological Transport, Active; Erythrocytes; Female; Humans; Lithium; Middle Aged; Sodium	1983
Effect of Li+ therapy and site of origin on cerebrospinal fluid beta-amyloid precursor protein derivatives. Biochemical Society transactions, 1993, Volume: 21 ( Pt 3), Issue:3 Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Antidepressive Agents; Antipsychotic Agents; Atrophy; Bipolar Disorder; Brain; Depressive Disorder; Female; Humans; Lithium; Male; Middle Aged	1993
Effects of chronic lithium treatment on platelet PKC isozymes in Alzheimer's and elderly control subjects. Neuroscience letters, 1993, Nov-12, Volume: 162, Issue:1-2 Topics: Aged; Alzheimer Disease; Blood Platelets; Blotting, Western; Cytosol; Humans; Isoenzymes; Lithium; Protein Kinase C	1993
Hypouricemia, abnormal renal tubular urate transport, and plasma natriuretic factor(s) in patients with Alzheimer's disease. Journal of the American Geriatrics Society, 1993, Volume: 41, Issue:5 Topics: Aged; Alzheimer Disease; Animals; Biological Assay; Case-Control Studies; Creatinine; Cross-Sectional Studies; Dementia, Multi-Infarct; Female; Humans; Kidney Function Tests; Kidney Tubules; Lithium; Male; Mental Status Schedule; Metabolic Clearance Rate; Natriuretic Agents; Phosphorus; Potassium; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Sodium; Uric Acid; Water-Electrolyte Imbalance	1993
Lithium inhibits Alzheimer's disease-like tau protein phosphorylation in neurons. FEBS letters, 1997, Jul-14, Volume: 411, Issue:2-3 Topics: Alzheimer Disease; Animals; Blotting, Western; Brain; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cyclin-Dependent Kinases; Enzyme Inhibitors; Flavonoids; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Humans; Kinetin; Lithium; Neurons; Okadaic Acid; Phosphorylation; Proline; Purines; Rats; tau Proteins	1997
Hyperosmotic stress-induced apoptosis and tau phosphorylation in human neuroblastoma cells. Journal of neuroscience research, 2001, Sep-15, Volume: 65, Issue:6 Topics: Alzheimer Disease; Apoptosis; Brain; Calcium-Calmodulin-Dependent Protein Kinases; Cysteine Proteinase Inhibitors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Humans; Lithium; Neuroblastoma; Neurons; Oligopeptides; Osmotic Pressure; Phosphorylation; Sorbitol; tau Proteins; Tumor Cells, Cultured	2001
Interaction of serotonin and melatonin with sodium, potassium, calcium, lithium and aluminium. Journal of pineal research, 2001, Volume: 31, Issue:2 Topics: Aluminum; Alzheimer Disease; Animals; Brain; Calcium; Electrochemistry; Humans; In Vitro Techniques; Lithium; Melatonin; Metals; Potassium; Psychopharmacology; Serotonin; Sodium	2001
Receptor reserve of phosphoinositide-coupled muscarinic receptors in mouse hippocampus in vivo. Brain research, 2001, Oct-19, Volume: 916, Issue:1-2 Topics: Acetylcholine; Alzheimer Disease; Animals; Cholinergic Fibers; Dioxolanes; Dose-Response Relationship, Drug; Drug Interactions; Hippocampus; Hydrolysis; Lithium; Male; Mice; Muscarinic Agonists; Muscarinic Antagonists; Oxotremorine; Phosphatidylinositols; Pilocarpine; Pirenzepine; Receptors, Muscarinic; Synaptic Transmission	2001
Medications to modify at-home behavior of Alzheimer's patients. Geriatrics, 1985, Volume: 40, Issue:12 Topics: Aged; Alzheimer Disease; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents; Behavior; Benzodiazepines; Electroconvulsive Therapy; Humans; Lithium; Maprotiline; Middle Aged; Monoamine Oxidase Inhibitors; Nomifensine; Psychotropic Drugs; Trazodone	1985
Lithium neurotoxicity in patients with degenerative brain disease. The Journal of clinical psychiatry, 1985, Volume: 46, Issue:8 Topics: Alzheimer Disease; Basal Ganglia Diseases; Dyskinesia, Drug-Induced; Hallucinations; Humans; Lithium; Receptors, Cholinergic; Receptors, Dopamine	1985
Psychopharmacology in the aged. Use of major psychotropic medications in treatment of the elderly: case examples. Journal of geriatric psychiatry, 1974, Volume: 7, Issue:2 Topics: Adjustment Disorders; Aged; Alzheimer Disease; Amitriptyline; Benztropine; Bipolar Disorder; Catatonia; Chlorpromazine; Dementia; Female; Humans; Lithium; Male; Mental Disorders; Psychopharmacology; Psychoses, Substance-Induced; Thioridazine; Tranquilizing Agents; Trifluoperazine	1974