Page last updated: 2024-08-24

lisofylline and Autoimmune Diabetes

lisofylline has been researched along with Autoimmune Diabetes in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (66.67)29.6817
2010's1 (11.11)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Chen, M; Cui, P; Macdonald, TL; Nadler, JL1
Chitkara, D; Italiya, KS; Mittal, A; Narisepalli, S; Singh, AK1
Basak, M; Chitkara, D; Italiya, KS; Mazumdar, S; Mittal, A; Sahel, DK; Shrivastava, R1
Chitkara, D; Italiya, KS; Mittal, A; Singh, AK1
Chen, M; McDuffie, M; Nadler, JL; Wu, R; Yang, ZD1
Chen, M; Ellett, JD; Fialkow, LB; Nadler, JL; Wu, R; Yang, Z1
Carter, JD; Chen, M; Ellett, JD; Fialkow, LB; Nadler, JL; Yang, Z1
Chen, M; Nadler, JL; Yang, Z1
Carter, JD; Chen, M; Garmey, JC; Kimble, SD; Nadler, JL; Nunemaker, CS; Yang, Z1

Reviews

1 review(s) available for lisofylline and Autoimmune Diabetes

ArticleYear
Lisofylline: a potential lead for the treatment of diabetes.
    Biochemical pharmacology, 2005, Jan-01, Volume: 69, Issue:1

    Topics: Animals; Diabetes Mellitus, Type 1; Humans; Islets of Langerhans; Pentoxifylline

2005

Other Studies

8 other study(ies) available for lisofylline and Autoimmune Diabetes

ArticleYear
Synthesis and biological evaluation of lisofylline (LSF) analogs as a potential treatment for Type 1 diabetes.
    Bioorganic & medicinal chemistry letters, 2006, Jul-01, Volume: 16, Issue:13

    Topics: Animals; Apoptosis; Cell Line; Chemoprevention; Cytokines; Diabetes Mellitus, Type 1; Drug Evaluation, Preclinical; Hypoglycemic Agents; Insulin; Insulin Secretion; Insulin-Secreting Cells; Mice; Molecular Structure; Pentoxifylline; Stereoisomerism

2006
Role of Chain Length and Degree of Unsaturation of Fatty Acids in the Physicochemical and Pharmacological Behavior of Drug-Fatty Acid Conjugates in Diabetes.
    Journal of medicinal chemistry, 2021, 10-14, Volume: 64, Issue:19

    Topics: Animals; Cell Line; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Fatty Acids; Hypoglycemic Agents; Mice; Molecular Structure; Prodrugs; Rats; Rats, Wistar; Streptozocin; Structure-Activity Relationship

2021
Scalable Self-Assembling Micellar System for Enhanced Oral Bioavailability and Efficacy of Lisofylline for Treatment of Type-I Diabetes.
    Molecular pharmaceutics, 2019, 12-02, Volume: 16, Issue:12

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Diabetes Mellitus, Type 1; Freeze Drying; Interferon-gamma; Male; Mice; Micelles; Pentoxifylline; Rats; Rats, Wistar; Treatment Outcome; Tumor Necrosis Factor-alpha

2019
Nanoparticulate tablet dosage form of lisofylline-linoleic acid conjugate for type 1 diabetes: in situ single-pass intestinal perfusion (SPIP) studies and pharmacokinetics in rat.
    AAPS PharmSciTech, 2021, Mar-24, Volume: 22, Issue:3

    Topics: Administration, Oral; Animals; Cell Line; Cell Survival; Diabetes Mellitus, Type 1; Dosage Forms; Jejunum; Linoleic Acid; Male; Mice; Nanoparticles; Pentoxifylline; Perfusion; Rats; Rats, Wistar; Tablets

2021
The anti-inflammatory compound lisofylline prevents Type I diabetes in non-obese diabetic mice.
    Diabetologia, 2002, Volume: 45, Issue:9

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Glucose; Cytokines; Diabetes Mellitus, Type 1; DNA Damage; Female; Incidence; Insulin; Insulin Secretion; Islets of Langerhans; Lymphocyte Transfusion; Mice; Mice, Inbred NOD; Mice, SCID; Pentoxifylline; Spleen

2002
Inhibition of STAT4 activation by lisofylline is associated with the protection of autoimmune diabetes.
    Annals of the New York Academy of Sciences, 2003, Volume: 1005

    Topics: Diabetes Mellitus, Type 1; DNA-Binding Proteins; Humans; Immunosuppressive Agents; Interleukin-12; Pentoxifylline; Phosphorylation; Signal Transduction; STAT4 Transcription Factor; Trans-Activators

2003
The novel anti-inflammatory agent lisofylline prevents autoimmune diabetic recurrence after islet transplantation.
    Transplantation, 2004, Jan-15, Volume: 77, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cytokines; Diabetes Mellitus, Type 1; Female; Graft Survival; Inflammation Mediators; Insulin; Insulin Secretion; Islets of Langerhans; Islets of Langerhans Transplantation; Mice; Mice, Inbred NOD; Mice, SCID; Pentoxifylline; Secondary Prevention; Time Factors; Transplantation, Homologous

2004
Combined treatment with lisofylline and exendin-4 reverses autoimmune diabetes.
    Biochemical and biophysical research communications, 2006, Jun-09, Volume: 344, Issue:3

    Topics: Animals; Diabetes Mellitus, Type 1; Drug Combinations; Exenatide; Insulin-Secreting Cells; Mice; Mice, Inbred C57BL; Pentoxifylline; Peptides; Treatment Outcome; Venoms

2006