liproxstatin-1 and Ototoxicity

liproxstatin-1 has been researched along with Ototoxicity* in 1 studies

Other Studies

1 other study(ies) available for liproxstatin-1 and Ototoxicity

Article	Year
Liproxstatin-1 Protects Hair Cell-Like HEI-OC1 Cells and Cochlear Hair Cells against Neomycin Ototoxicity. Oxidative medicine and cellular longevity, 2020, Volume: 2020 Ferroptosis is a recently discovered iron-dependent form of oxidative programmed cell death distinct from caspase-dependent apoptosis. In this study, we investigated the effect of ferroptosis in neomycin-induced hair cell loss by using selective ferroptosis inhibitor liproxstatin-1 (Lip-1). Cell viability was identified by CCK8 assay. The levels of reactive oxygen species (ROS) were determined by DCFH-DA and cellROX green staining. The mitochondrial membrane potential (ΔΨ Topics: Animals; Cell Line; Hair Cells, Auditory; Mice; Neomycin; Ototoxicity; Quinoxalines; Reactive Oxygen Species; Spiro Compounds	2020

Article

Year

Liproxstatin-1 Protects Hair Cell-Like HEI-OC1 Cells and Cochlear Hair Cells against Neomycin Ototoxicity.

Oxidative medicine and cellular longevity, 2020, Volume: 2020

Ferroptosis is a recently discovered iron-dependent form of oxidative programmed cell death distinct from caspase-dependent apoptosis. In this study, we investigated the effect of ferroptosis in neomycin-induced hair cell loss by using selective ferroptosis inhibitor liproxstatin-1 (Lip-1). Cell viability was identified by CCK8 assay. The levels of reactive oxygen species (ROS) were determined by DCFH-DA and cellROX green staining. The mitochondrial membrane potential (ΔΨ

Topics: Animals; Cell Line; Hair Cells, Auditory; Mice; Neomycin; Ototoxicity; Quinoxalines; Reactive Oxygen Species; Spiro Compounds

2020