lipoxin-b4 has been researched along with Diabetes-Mellitus--Type-2* in 1 studies
1 other study(ies) available for lipoxin-b4 and Diabetes-Mellitus--Type-2
| Article | Year |
|---|---|
Modulation of lipid mediator profile may contribute to amelioration of chronic inflammation in adipose tissue of obese mice by pioglitazone.
Thiazolidinediones exert their antidiabetic effect in part by ameliorating chronic inflammation in adipose tissue. However, the precise mechanism of this anti-inflammatory action has remained unclear. We here investigated the effects of the TZD pioglitazone on the lipid mediator profile of adipose tissue in obese diabetic KKAy mice by metabololipidomics analysis based on liquid chromatography and tandem mass spectrometry. Pioglitazone treatment increased the amounts of pro-resolving lipid mediators including lipoxin B Topics: 3T3-L1 Cells; Adipocytes; Adipose Tissue; Animals; Chronic Disease; Cytokines; Diabetes Mellitus, Type 2; Gene Expression Profiling; Hypoglycemic Agents; Inflammation; Lipid Metabolism; Lipoxins; Male; Mice; Mice, Obese; Obesity; Pioglitazone | 2018 |