lipid-a has been researched along with Pneumonia--Pneumococcal* in 1 studies
1 other study(ies) available for lipid-a and Pneumonia--Pneumococcal
Article | Year |
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The Biosynthetic Monophosphoryl Lipid A Enhances the Therapeutic Outcome of Antibiotic Therapy in Pneumococcal Pneumonia.
Alternative treatment strategies against bacterial infections are required to decrease the use of antibiotics. This study tested the hypothesis that stimulation of the innate immune receptor Toll-like receptor 4 can be combined with antibiotics to improve the treatment of invasive pneumonia. The efficacy of the biosynthetic monophosphoryl lipid A (MPLA), a clinically approved Toll-like receptor 4 activator, was tested in a mouse model of Topics: Animals; Anti-Bacterial Agents; Lipid A; Mice; Pneumonia, Pneumococcal; Treatment Outcome | 2021 |